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The map label for this gene is apbE [H]

Identifier: 73538988

GI number: 73538988

Start: 1903937

End: 1904920

Strand: Reverse

Name: apbE [H]

Synonym: Reut_B5164

Alternate gene names: 73538988

Gene position: 1904920-1903937 (Counterclockwise)

Preceding gene: 73538989

Following gene: 73538987

Centisome position: 69.88

GC content: 65.14

Gene sequence:

>984_bases
ATGTCGAAGATGTCTATTGAGGGGGCGCCTGACCTGCAGCTCAAGCGCTTCCGGGTGACCGGCGCGACGATGGGCACGCG
GTACTCTGCGACGTTCCACGCGTCCCCGGAGACCGATGAAAGCGAACTTGCTGCGGAGCTTGCTGCTGCCGTAGGCGCGG
TTGACGAGCAGATGTCGAACTGGAAGGACAGTTCCGACCTGTCTCGCCTGAATCGCGCCGAGCCGAACTGCTGGGTGCAG
GTCTCCGGCAATCTCGCGGCTTTGCTCGTGCGTGCGCTGGAGATCGGCCGTGACACCCACAATGCCTTCAACATCGGCGT
CGGTGACCTGGTCGGCATGTGGGGCTTTGGGCCATCGGGGGAACAGCGTGCACATCGTCCGGGCGGAGTGGGCACGTCGC
GGGCAAGCCCGTGCCCGCCTGTGAGCGATCTGATCGACGTGGACGTGCAACAGTGCCGGGTGCGCAAGCGGGAACCCGTT
GCGCTTGATCTGTGCGGCATTGCAAAGGGATTCGGCGTCGACGAACTCGCGCGCGTGTTGAGCGAGCACGGGATCGGCTC
ATGGCTTGTCGGCATCGACGGTGAAATGCGCGCGCGCGGAAGCAAACCGGACGGGCCGCCGTGGGCGATCGCGCTTGAGG
CCCCGGATTACGACCGACACGCAGCAATGGCCGTGATCGAACTGAGTAACGCCGCCATCGCGACGTCCGGCGACTACCGC
CACTGGGCTGACATCGATGGTACACGCGTCTCGCACACAATGGATCCCCGAACTGGCGCGCCACTGTGCGGGTCCGTTGC
GTCCGTGACGGTACTTGCCCCGACATGCGCGGACGCGGACGCCTACGCAACAGCCTTGCTGGTGCTCGGCTTGCAGGCGG
GGCGAGACTATGCGCATTGCCGGCGCCTCGACGCACTCTTCATCGTACGCGACGGCGATGCGCTGCGTGCGATCGGGACT
GGCTGCTTTGCCAATGTGCAATAG

Upstream 100 bases:

>100_bases
TGCGGTGGCCGAAGGATGGCGGAGGGGGTCGCACAGGCGTGGGAACGCATTTTGACGGGTACCGGCTTGTCCGTCGCACA
ACTGAGAGCACAGGGACGTT

Downstream 100 bases:

>100_bases
GACCTTGGCCAATTCTTGCTACCGGTATGAGCTTTAGCCATGCACTCAGCGCGGCGCTGTCTTCCGTGACGGCATTCCGA
TTATGGACATCATCCAGACC

Product: ApbE-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSKMSIEGAPDLQLKRFRVTGATMGTRYSATFHASPETDESELAAELAAAVGAVDEQMSNWKDSSDLSRLNRAEPNCWVQ
VSGNLAALLVRALEIGRDTHNAFNIGVGDLVGMWGFGPSGEQRAHRPGGVGTSRASPCPPVSDLIDVDVQQCRVRKREPV
ALDLCGIAKGFGVDELARVLSEHGIGSWLVGIDGEMRARGSKPDGPPWAIALEAPDYDRHAAMAVIELSNAAIATSGDYR
HWADIDGTRVSHTMDPRTGAPLCGSVASVTVLAPTCADADAYATALLVLGLQAGRDYAHCRRLDALFIVRDGDALRAIGT
GCFANVQ

Sequences:

>Translated_327_residues
MSKMSIEGAPDLQLKRFRVTGATMGTRYSATFHASPETDESELAAELAAAVGAVDEQMSNWKDSSDLSRLNRAEPNCWVQ
VSGNLAALLVRALEIGRDTHNAFNIGVGDLVGMWGFGPSGEQRAHRPGGVGTSRASPCPPVSDLIDVDVQQCRVRKREPV
ALDLCGIAKGFGVDELARVLSEHGIGSWLVGIDGEMRARGSKPDGPPWAIALEAPDYDRHAAMAVIELSNAAIATSGDYR
HWADIDGTRVSHTMDPRTGAPLCGSVASVTVLAPTCADADAYATALLVLGLQAGRDYAHCRRLDALFIVRDGDALRAIGT
GCFANVQ
>Mature_326_residues
SKMSIEGAPDLQLKRFRVTGATMGTRYSATFHASPETDESELAAELAAAVGAVDEQMSNWKDSSDLSRLNRAEPNCWVQV
SGNLAALLVRALEIGRDTHNAFNIGVGDLVGMWGFGPSGEQRAHRPGGVGTSRASPCPPVSDLIDVDVQQCRVRKREPVA
LDLCGIAKGFGVDELARVLSEHGIGSWLVGIDGEMRARGSKPDGPPWAIALEAPDYDRHAAMAVIELSNAAIATSGDYRH
WADIDGTRVSHTMDPRTGAPLCGSVASVTVLAPTCADADAYATALLVLGLQAGRDYAHCRRLDALFIVRDGDALRAIGTG
CFANVQ

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=300, Percent_Identity=32.3333333333333, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34679; Mature: 34548

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKMSIEGAPDLQLKRFRVTGATMGTRYSATFHASPETDESELAAELAAAVGAVDEQMSN
CCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
WKDSSDLSRLNRAEPNCWVQVSGNLAALLVRALEIGRDTHNAFNIGVGDLVGMWGFGPSG
CCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCCC
EQRAHRPGGVGTSRASPCPPVSDLIDVDVQQCRVRKREPVALDLCGIAKGFGVDELARVL
CCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCCCCEEEEHHHHCCCCHHHHHHHH
SEHGIGSWLVGIDGEMRARGSKPDGPPWAIALEAPDYDRHAAMAVIELSNAAIATSGDYR
HHCCCCEEEEECCCHHHCCCCCCCCCCEEEEEECCCCCCHHEEEEEEECCCEEEECCCCC
HWADIDGTRVSHTMDPRTGAPLCGSVASVTVLAPTCADADAYATALLVLGLQAGRDYAHC
EECCCCCCEEEEECCCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHH
RRLDALFIVRDGDALRAIGTGCFANVQ
HCCCEEEEEECCCHHHHHCCCEEECCC
>Mature Secondary Structure 
SKMSIEGAPDLQLKRFRVTGATMGTRYSATFHASPETDESELAAELAAAVGAVDEQMSN
CCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
WKDSSDLSRLNRAEPNCWVQVSGNLAALLVRALEIGRDTHNAFNIGVGDLVGMWGFGPSG
CCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCCC
EQRAHRPGGVGTSRASPCPPVSDLIDVDVQQCRVRKREPVALDLCGIAKGFGVDELARVL
CCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCCCCEEEEHHHHCCCCHHHHHHHH
SEHGIGSWLVGIDGEMRARGSKPDGPPWAIALEAPDYDRHAAMAVIELSNAAIATSGDYR
HHCCCCEEEEECCCHHHCCCCCCCCCCEEEEEECCCCCCHHEEEEEEECCCEEEECCCCC
HWADIDGTRVSHTMDPRTGAPLCGSVASVTVLAPTCADADAYATALLVLGLQAGRDYAHC
EECCCCCCEEEEECCCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHH
RRLDALFIVRDGDALRAIGTGCFANVQ
HCCCEEEEEECCCHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]