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The map label for this gene is yyaJ [H]

Identifier: 73538968

GI number: 73538968

Start: 1884058

End: 1885506

Strand: Direct

Name: yyaJ [H]

Synonym: Reut_B5143

Alternate gene names: 73538968

Gene position: 1884058-1885506 (Clockwise)

Preceding gene: 73538967

Following gene: 73538969

Centisome position: 69.11

GC content: 62.87

Gene sequence:

>1449_bases
ATGGGCGCAGAAGTGAATGTCCAATCATCGAGTTCGCCCCAGCAGCACGAACTCGACCGGGCAATGGATGGCATCGGCGT
CACCGCCGCACACAAGAAGATCATCTTCCTGATCATGCTGGGCGTGATGTTCGATGTCTTTGAACAGAACGCCGTGGGCC
TGGTGGGGCCCATTTTGCGCGAGCAATGGGGCATATCGGTCGCGCATATCGGCTTTCTCAATACGCTGACGTTCAGCGCA
GCGGCACTGGGCCGCGTCGCATCGGGCTATATCGCCGATCGCTACGGCCGTCGCGCGATGCTGAATGCGAACCTGCTGCT
GTTCACGCTCGGTGCGGTCATCTGCGCGCTGGCGCCGAACTATACGGTGCTGGCCGCGGGCCGGTTCATCGTCGGCATCG
GCCTGGGTGGTGAAATCTCGGTGGCCGTGACAATCCTTGCCGAGCTGTGCTCGACCCGTTTCCGCGGCACCGCGGTCGGC
ATGGTCAGCGTGGGCAGCGGCGGTCTGGGCAATATGCTGGCACCCGCGTTCGGCTTGGCCGTGTTCGCGCTGTTCCCCGG
ACCGGACAGCTGGCGGTGGCTGTTCGGCTGCCTGGTCGTGCCCGCCATCTTCGTCGTGTTCTACCGTCGCTTTATTCCCG
AGACGCCTCGCTTCCTGCTGTCGAAGGGCCGCGTGGACGAGGCGAACCGTGTGCTCTCCGGCCTCGCTTCCGGGCGTCTG
GGCAAGCTGCGCGGAGAACCGACACAGTACATCCGGGAGGCCGTTCAGGACGATTCGCCACGGGCCAGGGTACGGTTGCG
CGATGTGTTCCAGGGTCGCTTGGGCCGGCGCACGGTCGCGTTGGGTATCGCGGTCTCGATGACATACGGCGCGCAGATTT
CAGTGCTGACGTTGATGCCCACGATCCTGATGTCGCAGGGATACACCATCTCGAAAAGCCTGTTGTTCACCATGGTGATG
CAAAGCGGAAGCCTGTTCGGCGCGCTGGCAGCTTCGTATTGCGGCTACCACTTTCCGCGCAAGCGCGTGCTGACCATTGG
TGCGGGACTGGCATGCGCGGCAGGGCTGAGTTTCGGCTTCCTGACGTTCAATGTGGGATTGGTGCTGTTGTTCGGGGCGT
GCTTTACGTTCTGCGTGGTGCTGCTGAACACCTCGATCTGGATCTTTGCCCCCGAGCAATATCCCACCGATGTCCGTGCT
TTCGGCACCTCGCTCATTCTCGCGCTGGGTACGCTGGCCGGTGCGTTGACACCGCTGATCAGTGGCCGCGTGTTCGAAAG
CTACGGCGTGGGTGGCATGTTCAGCATGCTGGCCGCCATGTACGCTGTGTTCGCGCTAAGCGTACAGTTTGCGCCTGAGA
CCTTCGGCCGCCCCATGGGTGAACCCGAACCGGAAGACACGGCAGAGTTGGCAGTCGGCACGGGTACCGCCAGTGCCAGC
GGATCCTGA

Upstream 100 bases:

>100_bases
GCCGCACTTTCATGACTGCTCTGTTCCAATGCCGGCCAGCGATGCCGGCAGCAAGTTTGCGGACACACCGTAACTGACCT
CATTTCGAGGAGGAGACAAG

Downstream 100 bases:

>100_bases
CTCAAGCAATGACATGAATCCGATCCTGTTAATCAACCCTAATACGTCGCAGGCAACCACGCAGATGATGGTGGAGATTG
CGCGTTCCAGCCTGGGCGGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MGAEVNVQSSSSPQQHELDRAMDGIGVTAAHKKIIFLIMLGVMFDVFEQNAVGLVGPILREQWGISVAHIGFLNTLTFSA
AALGRVASGYIADRYGRRAMLNANLLLFTLGAVICALAPNYTVLAAGRFIVGIGLGGEISVAVTILAELCSTRFRGTAVG
MVSVGSGGLGNMLAPAFGLAVFALFPGPDSWRWLFGCLVVPAIFVVFYRRFIPETPRFLLSKGRVDEANRVLSGLASGRL
GKLRGEPTQYIREAVQDDSPRARVRLRDVFQGRLGRRTVALGIAVSMTYGAQISVLTLMPTILMSQGYTISKSLLFTMVM
QSGSLFGALAASYCGYHFPRKRVLTIGAGLACAAGLSFGFLTFNVGLVLLFGACFTFCVVLLNTSIWIFAPEQYPTDVRA
FGTSLILALGTLAGALTPLISGRVFESYGVGGMFSMLAAMYAVFALSVQFAPETFGRPMGEPEPEDTAELAVGTGTASAS
GS

Sequences:

>Translated_482_residues
MGAEVNVQSSSSPQQHELDRAMDGIGVTAAHKKIIFLIMLGVMFDVFEQNAVGLVGPILREQWGISVAHIGFLNTLTFSA
AALGRVASGYIADRYGRRAMLNANLLLFTLGAVICALAPNYTVLAAGRFIVGIGLGGEISVAVTILAELCSTRFRGTAVG
MVSVGSGGLGNMLAPAFGLAVFALFPGPDSWRWLFGCLVVPAIFVVFYRRFIPETPRFLLSKGRVDEANRVLSGLASGRL
GKLRGEPTQYIREAVQDDSPRARVRLRDVFQGRLGRRTVALGIAVSMTYGAQISVLTLMPTILMSQGYTISKSLLFTMVM
QSGSLFGALAASYCGYHFPRKRVLTIGAGLACAAGLSFGFLTFNVGLVLLFGACFTFCVVLLNTSIWIFAPEQYPTDVRA
FGTSLILALGTLAGALTPLISGRVFESYGVGGMFSMLAAMYAVFALSVQFAPETFGRPMGEPEPEDTAELAVGTGTASAS
GS
>Mature_481_residues
GAEVNVQSSSSPQQHELDRAMDGIGVTAAHKKIIFLIMLGVMFDVFEQNAVGLVGPILREQWGISVAHIGFLNTLTFSAA
ALGRVASGYIADRYGRRAMLNANLLLFTLGAVICALAPNYTVLAAGRFIVGIGLGGEISVAVTILAELCSTRFRGTAVGM
VSVGSGGLGNMLAPAFGLAVFALFPGPDSWRWLFGCLVVPAIFVVFYRRFIPETPRFLLSKGRVDEANRVLSGLASGRLG
KLRGEPTQYIREAVQDDSPRARVRLRDVFQGRLGRRTVALGIAVSMTYGAQISVLTLMPTILMSQGYTISKSLLFTMVMQ
SGSLFGALAASYCGYHFPRKRVLTIGAGLACAAGLSFGFLTFNVGLVLLFGACFTFCVVLLNTSIWIFAPEQYPTDVRAF
GTSLILALGTLAGALTPLISGRVFESYGVGGMFSMLAAMYAVFALSVQFAPETFGRPMGEPEPEDTAELAVGTGTASASG
S

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=496, Percent_Identity=24.7983870967742, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI24308167, Length=518, Percent_Identity=22.2007722007722, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI203098995, Length=179, Percent_Identity=34.0782122905028, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4506999, Length=391, Percent_Identity=24.8081841432225, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI90669191, Length=376, Percent_Identity=26.8617021276596, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI21553331, Length=299, Percent_Identity=25.0836120401338, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI24497497, Length=376, Percent_Identity=26.5957446808511, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI302148518, Length=352, Percent_Identity=24.1477272727273, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI166064021, Length=164, Percent_Identity=34.1463414634146, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI23510410, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI166795299, Length=241, Percent_Identity=28.6307053941909, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4507005, Length=395, Percent_Identity=23.5443037974684, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI7662270, Length=243, Percent_Identity=24.6913580246914, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI166197673, Length=416, Percent_Identity=25.7211538461538, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI216548223, Length=323, Percent_Identity=23.8390092879257, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788074, Length=438, Percent_Identity=28.5388127853881, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786229, Length=451, Percent_Identity=24.1685144124169, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788068, Length=476, Percent_Identity=26.0504201680672, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789207, Length=476, Percent_Identity=25.6302521008403, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082159, Length=379, Percent_Identity=27.1767810026385, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789312, Length=390, Percent_Identity=25.8974358974359, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082404, Length=434, Percent_Identity=24.1935483870968, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082231, Length=179, Percent_Identity=27.9329608938547, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790463, Length=444, Percent_Identity=24.0990990990991, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081723, Length=347, Percent_Identity=25.6484149855908, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565978, Length=206, Percent_Identity=32.5242718446602, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32564663, Length=497, Percent_Identity=23.3400402414487, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17565976, Length=191, Percent_Identity=31.413612565445, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25148667, Length=232, Percent_Identity=25.4310344827586, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=137, Percent_Identity=32.8467153284672, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324469, Length=395, Percent_Identity=22.5316455696203, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922616, Length=406, Percent_Identity=25.1231527093596, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19922874, Length=458, Percent_Identity=23.5807860262009, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649616, Length=186, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649618, Length=440, Percent_Identity=25.2272727272727, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161077756, Length=478, Percent_Identity=23.2217573221757, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573097, Length=240, Percent_Identity=21.6666666666667, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24663515, Length=406, Percent_Identity=23.6453201970443, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24663519, Length=406, Percent_Identity=23.6453201970443, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24663511, Length=406, Percent_Identity=23.6453201970443, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI62484254, Length=444, Percent_Identity=23.8738738738739, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51122; Mature: 50990

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAEVNVQSSSSPQQHELDRAMDGIGVTAAHKKIIFLIMLGVMFDVFEQNAVGLVGPILR
CCCEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EQWGISVAHIGFLNTLTFSAAALGRVASGYIADRYGRRAMLNANLLLFTLGAVICALAPN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCC
YTVLAAGRFIVGIGLGGEISVAVTILAELCSTRFRGTAVGMVSVGSGGLGNMLAPAFGLA
CEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHH
VFALFPGPDSWRWLFGCLVVPAIFVVFYRRFIPETPRFLLSKGRVDEANRVLSGLASGRL
HEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCC
GKLRGEPTQYIREAVQDDSPRARVRLRDVFQGRLGRRTVALGIAVSMTYGAQISVLTLMP
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCHHHHHHH
TILMSQGYTISKSLLFTMVMQSGSLFGALAASYCGYHFPRKRVLTIGAGLACAAGLSFGF
HHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHH
LTFNVGLVLLFGACFTFCVVLLNTSIWIFAPEQYPTDVRAFGTSLILALGTLAGALTPLI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGRVFESYGVGGMFSMLAAMYAVFALSVQFAPETFGRPMGEPEPEDTAELAVGTGTASAS
CCCHHHHCCCCHHHHHHHHHHHHHHHHHEECHHHHCCCCCCCCCCCCHHEEEECCCCCCC
GS
CC
>Mature Secondary Structure 
GAEVNVQSSSSPQQHELDRAMDGIGVTAAHKKIIFLIMLGVMFDVFEQNAVGLVGPILR
CCEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EQWGISVAHIGFLNTLTFSAAALGRVASGYIADRYGRRAMLNANLLLFTLGAVICALAPN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCC
YTVLAAGRFIVGIGLGGEISVAVTILAELCSTRFRGTAVGMVSVGSGGLGNMLAPAFGLA
CEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHH
VFALFPGPDSWRWLFGCLVVPAIFVVFYRRFIPETPRFLLSKGRVDEANRVLSGLASGRL
HEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCC
GKLRGEPTQYIREAVQDDSPRARVRLRDVFQGRLGRRTVALGIAVSMTYGAQISVLTLMP
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCHHHHHHH
TILMSQGYTISKSLLFTMVMQSGSLFGALAASYCGYHFPRKRVLTIGAGLACAAGLSFGF
HHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHH
LTFNVGLVLLFGACFTFCVVLLNTSIWIFAPEQYPTDVRAFGTSLILALGTLAGALTPLI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGRVFESYGVGGMFSMLAAMYAVFALSVQFAPETFGRPMGEPEPEDTAELAVGTGTASAS
CCCHHHHCCCCHHHHHHHHHHHHHHHHHEECHHHHCCCCCCCCCCCCHHEEEECCCCCCC
GS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]