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The map label for this gene is etfA [H]

Identifier: 73538642

GI number: 73538642

Start: 1517704

End: 1518870

Strand: Reverse

Name: etfA [H]

Synonym: Reut_B4817

Alternate gene names: 73538642

Gene position: 1518870-1517704 (Counterclockwise)

Preceding gene: 73538643

Following gene: 73538641

Centisome position: 55.71

GC content: 69.07

Gene sequence:

>1167_bases
ATGAACCAGATCCCACGTATCGATCCACGTCGGCCGTTCGTGATCACAGCGGCCGGCCTGAGAAGGATTACACTCGGCGA
GACCGGCAGCGCGGATCCGAACGCTGCACACTGGTCCGCGCACGGCCACGGCACGGCGGCAAGGCCGCGCCGCGCCGTCA
GCGATCCGCGGCACGTGCTGCTCGTTGTCGCGCACAGCGAGCGCGGCGCGCTGGACGACCATGCGTGCCAGGCGCTCGCC
GCGGCGGCGCTGCTTGCCGATGCGCAGACCGAGGTCGCGCTGCTGGTGTTCGGCGAACTGAAGGACGACGCGGCACCGCT
CGGCGCCGACAAGGTCATTGCCCTGCCCACCTTCGATCGCCGCGCCTTTGCGCCCGATGCCGAACTGCGGGCGCTGCTGG
CCTGCGCGGCCGCGCTGTCGCCTAAACATCTTTTCCTGCCGGATAACGCGACCGGCGATGGCGATCTGGGCCGCCGCTAC
GCGGCCGCAACCGGTGCGAGCGTCGCGACGCACGTGGTCGAGATCGACGCGGGCCACGTCGGCACCTACGCACAGGTGAA
ACGCGCCTTTGCGACACGCTCGCTGCCCGACGTGATCCTGCTTGCGCCGGGCGCGGTCGACACGAAGCTCCCGTTCACCG
GCGCGGGCGAGTCGTTGTCAGGCGACTTCCTGCTCGGCATTGGCGATGGTGCGCAGCCGTATCGCGACCTGGGCCTCGAG
GAGATCGATGCCGCACAGGTCGCGCTCGAGGAGGCGGACTTCATCGTGTCTGCCGGCAATGGCGTGGCCGATATCGGCGC
GTTCGAGCAGCTTGCCGGCGTGTTCGGCGCAGCAATCGCCGCGAGCCGCGTCGCCGTCGACAATGGCCATTTCACGCGCG
ACAAGCAGGTCGGCGCGACCGGCAAGACCGTAGAGGCGAGTGTCTATATCGCGTTTGGCATCTCTGGCGCCGTGCAGCAC
CTGCAGGGCATCAAGGACTGCCGTCACGTGATCGCCGTCAATCTGGACGGCAGCGCGCCCATTGCCAAGCGCGCGAACCT
GACCATCGTCGGCGATGCGAACGAGACGATCGCGGCGCTGATGGCAGCGGTGCAGGCCGCACGCCGCACCAACGGAAGGG
CGCCGGCAGCGGCCAGCGTCCGCGAACCGCTAGGAGCCGCAGCATGA

Upstream 100 bases:

>100_bases
GGATGCCCGAACTGCACGGCAATGCTCGAAGGCGTCGTCGGTCCACGCCCGGATGTGCTGGATGTGGCCGAACTTGTTGC
GGCCTCGCTGGAGTGACTCG

Downstream 100 bases:

>100_bases
ACGCCCCCCAACAAATCCGGCGCATCGCGGTGCTCGTGTCTATTGGCCGTCATCCGGTCAGCGGCGCTACGCGCTATAGC
CGCAACGATGCCGCGGCGCT

Product: electron transfer flavoprotein subunit beta:electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNQIPRIDPRRPFVITAAGLRRITLGETGSADPNAAHWSAHGHGTAARPRRAVSDPRHVLLVVAHSERGALDDHACQALA
AAALLADAQTEVALLVFGELKDDAAPLGADKVIALPTFDRRAFAPDAELRALLACAAALSPKHLFLPDNATGDGDLGRRY
AAATGASVATHVVEIDAGHVGTYAQVKRAFATRSLPDVILLAPGAVDTKLPFTGAGESLSGDFLLGIGDGAQPYRDLGLE
EIDAAQVALEEADFIVSAGNGVADIGAFEQLAGVFGAAIAASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISGAVQH
LQGIKDCRHVIAVNLDGSAPIAKRANLTIVGDANETIAALMAAVQAARRTNGRAPAAASVREPLGAAA

Sequences:

>Translated_388_residues
MNQIPRIDPRRPFVITAAGLRRITLGETGSADPNAAHWSAHGHGTAARPRRAVSDPRHVLLVVAHSERGALDDHACQALA
AAALLADAQTEVALLVFGELKDDAAPLGADKVIALPTFDRRAFAPDAELRALLACAAALSPKHLFLPDNATGDGDLGRRY
AAATGASVATHVVEIDAGHVGTYAQVKRAFATRSLPDVILLAPGAVDTKLPFTGAGESLSGDFLLGIGDGAQPYRDLGLE
EIDAAQVALEEADFIVSAGNGVADIGAFEQLAGVFGAAIAASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISGAVQH
LQGIKDCRHVIAVNLDGSAPIAKRANLTIVGDANETIAALMAAVQAARRTNGRAPAAASVREPLGAAA
>Mature_388_residues
MNQIPRIDPRRPFVITAAGLRRITLGETGSADPNAAHWSAHGHGTAARPRRAVSDPRHVLLVVAHSERGALDDHACQALA
AAALLADAQTEVALLVFGELKDDAAPLGADKVIALPTFDRRAFAPDAELRALLACAAALSPKHLFLPDNATGDGDLGRRY
AAATGASVATHVVEIDAGHVGTYAQVKRAFATRSLPDVILLAPGAVDTKLPFTGAGESLSGDFLLGIGDGAQPYRDLGLE
EIDAAQVALEEADFIVSAGNGVADIGAFEQLAGVFGAAIAASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISGAVQH
LQGIKDCRHVIAVNLDGSAPIAKRANLTIVGDANETIAALMAAVQAARRTNGRAPAAASVREPLGAAA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=115, Percent_Identity=43.4782608695652, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4503607, Length=107, Percent_Identity=46.7289719626168, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786226, Length=122, Percent_Identity=36.0655737704918, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787990, Length=125, Percent_Identity=31.2, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=131, Percent_Identity=41.2213740458015, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6325261, Length=116, Percent_Identity=42.2413793103448, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17136898, Length=137, Percent_Identity=41.6058394160584, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652801, Length=137, Percent_Identity=41.6058394160584, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 39839; Mature: 39839

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIPRIDPRRPFVITAAGLRRITLGETGSADPNAAHWSAHGHGTAARPRRAVSDPRHVL
CCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHCCCCCEEE
LVVAHSERGALDDHACQALAAAALLADAQTEVALLVFGELKDDAAPLGADKVIALPTFDR
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCC
RAFAPDAELRALLACAAALSPKHLFLPDNATGDGDLGRRYAAATGASVATHVVEIDAGHV
CCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCC
GTYAQVKRAFATRSLPDVILLAPGAVDTKLPFTGAGESLSGDFLLGIGDGAQPYRDLGLE
CHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCH
EIDAAQVALEEADFIVSAGNGVADIGAFEQLAGVFGAAIAASRVAVDNGHFTRDKQVGAT
HHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCC
GKTVEASVYIAFGISGAVQHLQGIKDCRHVIAVNLDGSAPIAKRANLTIVGDANETIAAL
CCEEEEEEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHH
MAAVQAARRTNGRAPAAASVREPLGAAA
HHHHHHHHHCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MNQIPRIDPRRPFVITAAGLRRITLGETGSADPNAAHWSAHGHGTAARPRRAVSDPRHVL
CCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHCCCCCEEE
LVVAHSERGALDDHACQALAAAALLADAQTEVALLVFGELKDDAAPLGADKVIALPTFDR
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCC
RAFAPDAELRALLACAAALSPKHLFLPDNATGDGDLGRRYAAATGASVATHVVEIDAGHV
CCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCC
GTYAQVKRAFATRSLPDVILLAPGAVDTKLPFTGAGESLSGDFLLGIGDGAQPYRDLGLE
CHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCH
EIDAAQVALEEADFIVSAGNGVADIGAFEQLAGVFGAAIAASRVAVDNGHFTRDKQVGAT
HHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCC
GKTVEASVYIAFGISGAVQHLQGIKDCRHVIAVNLDGSAPIAKRANLTIVGDANETIAAL
CCEEEEEEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHH
MAAVQAARRTNGRAPAAASVREPLGAAA
HHHHHHHHHCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]