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The map label for this gene is trxB [H]

Identifier: 73538272

GI number: 73538272

Start: 1106396

End: 1107412

Strand: Reverse

Name: trxB [H]

Synonym: Reut_B4445

Alternate gene names: 73538272

Gene position: 1107412-1106396 (Counterclockwise)

Preceding gene: 73538275

Following gene: 73538271

Centisome position: 40.62

GC content: 64.11

Gene sequence:

>1017_bases
ATGGGCAACTTTCTCGCCAGTGCCGAAGCCCTCTGGCCGCGGATCGTCTCAAGCGCTTATCTCCGGACGTTATTGCGCAC
CGGGCCCAGCCACCCCTCTATCCACAACACGGAGCCCATCACCATGAATGACGTCATCATCATCGGCGGCAGCTTTGCCG
GGCTCGCCGCCGCCCTGCAGCTCGGCCGTGCGCGCCGCAAGGTCACCGTGCTCGATACCGGCCGACCGCGCAACCGCTTT
GCCGGCCACTCGCATGGCCTGCTCGGCCACGATCACAAGCCGCCGCTGGACATCCTAGTCGAGGCGCGGCAGCAGCTTGC
GCGCTATCCAACGATCAGGCTGGTCATAGCTCGGGCCGAGAGCGTGTCTGGCGCCATCGACGATTTCTGCGTCGTCACTG
ACGATCAGGAAAGCCTAAGGGCGCGCCGCCTCATCCTGAGCTATGGCGTCGCCGACCAGATGCCTGATGTTCCGGGCTTT
GCCGAAAGCTGGGGCACGTCCATCGTGCCCTGCCCCTATTGCGACGGCTTTGAAGTCGCCGGCCAGCATTGGGGCCTTCT
CTGGTCCGGCCCACAGTCGCACCAGTCTGCCAGGCTGTTCCGCGATTGGACTGACAAGTTGACTGTCTTCGCCGATGGTC
ATGACATTGCGGCCGATATCCAGGCCGATCTGGCGCGCCGCAACATGCCTGTCGTCGATGGCCGGATCGTCGAGATCGCC
CATCACACGGGCCATATCACCACCGTCAATCTCGATACCGGCCGCAATGTCGCGGTCGACGTCCTGTTCGCCCATCCGCG
CAACAAGCCGTCCGCAAGCCTGCATGAATCACTGGGCCTCGCCACGGTCGATACGCCCACTGGCATCGTCCTCAAAGTCG
ACGAGCGCCGCCAAACCAGCATCCCCGGCATCTACGCCGCTGGCGACCTCGCCACGCCCTTCTTGCCCTCGGTCACCCAG
GCATCATCGCAGGGCGCGATGGCGGGTATCTTCGCCCAGCAGTCGATGGTTGTTTGA

Upstream 100 bases:

>100_bases
GAGCAAGCCAAGGGTATGTTTTAACCGGTTGTCCAAATCAGCTTTCCACTGGCCGCCCGGCGATAACGAATGCGGCATTG
TCCGGCCGGTCAATACAGTC

Downstream 100 bases:

>100_bases
GAGTACAGATTCCTTTCTCCCGTTGCGTCGTCGCCTTCGAAAAGGTCGGCGTAGGAGCAACCTATGGATGATGCGTGGAC
GGCTGATGGGCGAGGCCGTT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TR; TRXR [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MGNFLASAEALWPRIVSSAYLRTLLRTGPSHPSIHNTEPITMNDVIIIGGSFAGLAAALQLGRARRKVTVLDTGRPRNRF
AGHSHGLLGHDHKPPLDILVEARQQLARYPTIRLVIARAESVSGAIDDFCVVTDDQESLRARRLILSYGVADQMPDVPGF
AESWGTSIVPCPYCDGFEVAGQHWGLLWSGPQSHQSARLFRDWTDKLTVFADGHDIAADIQADLARRNMPVVDGRIVEIA
HHTGHITTVNLDTGRNVAVDVLFAHPRNKPSASLHESLGLATVDTPTGIVLKVDERRQTSIPGIYAAGDLATPFLPSVTQ
ASSQGAMAGIFAQQSMVV

Sequences:

>Translated_338_residues
MGNFLASAEALWPRIVSSAYLRTLLRTGPSHPSIHNTEPITMNDVIIIGGSFAGLAAALQLGRARRKVTVLDTGRPRNRF
AGHSHGLLGHDHKPPLDILVEARQQLARYPTIRLVIARAESVSGAIDDFCVVTDDQESLRARRLILSYGVADQMPDVPGF
AESWGTSIVPCPYCDGFEVAGQHWGLLWSGPQSHQSARLFRDWTDKLTVFADGHDIAADIQADLARRNMPVVDGRIVEIA
HHTGHITTVNLDTGRNVAVDVLFAHPRNKPSASLHESLGLATVDTPTGIVLKVDERRQTSIPGIYAAGDLATPFLPSVTQ
ASSQGAMAGIFAQQSMVV
>Mature_337_residues
GNFLASAEALWPRIVSSAYLRTLLRTGPSHPSIHNTEPITMNDVIIIGGSFAGLAAALQLGRARRKVTVLDTGRPRNRFA
GHSHGLLGHDHKPPLDILVEARQQLARYPTIRLVIARAESVSGAIDDFCVVTDDQESLRARRLILSYGVADQMPDVPGFA
ESWGTSIVPCPYCDGFEVAGQHWGLLWSGPQSHQSARLFRDWTDKLTVFADGHDIAADIQADLARRNMPVVDGRIVEIAH
HTGHITTVNLDTGRNVAVDVLFAHPRNKPSASLHESLGLATVDTPTGIVLKVDERRQTSIPGIYAAGDLATPFLPSVTQA
SSQGAMAGIFAQQSMVV

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 36535; Mature: 36404

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNFLASAEALWPRIVSSAYLRTLLRTGPSHPSIHNTEPITMNDVIIIGGSFAGLAAALQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEEEECCCHHHHHHHHH
LGRARRKVTVLDTGRPRNRFAGHSHGLLGHDHKPPLDILVEARQQLARYPTIRLVIARAE
HHHHHCEEEEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECC
SVSGAIDDFCVVTDDQESLRARRLILSYGVADQMPDVPGFAESWGTSIVPCPYCDGFEVA
CCCCCCCCEEEEECCHHHHHHHHHHHHHCCHHCCCCCCCHHHHCCCCCCCCCCCCCCCCC
GQHWGLLWSGPQSHQSARLFRDWTDKLTVFADGHDIAADIQADLARRNMPVVDGRIVEIA
CCCCCEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEE
HHTGHITTVNLDTGRNVAVDVLFAHPRNKPSASLHESLGLATVDTPTGIVLKVDERRQTS
ECCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHCCEEEECCCCCEEEEECCCCCCC
IPGIYAAGDLATPFLPSVTQASSQGAMAGIFAQQSMVV
CCCEEECCCCCCCCCCCHHHCCCCCCEEEEHHHCCCCC
>Mature Secondary Structure 
GNFLASAEALWPRIVSSAYLRTLLRTGPSHPSIHNTEPITMNDVIIIGGSFAGLAAALQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEEEECCCHHHHHHHHH
LGRARRKVTVLDTGRPRNRFAGHSHGLLGHDHKPPLDILVEARQQLARYPTIRLVIARAE
HHHHHCEEEEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECC
SVSGAIDDFCVVTDDQESLRARRLILSYGVADQMPDVPGFAESWGTSIVPCPYCDGFEVA
CCCCCCCCEEEEECCHHHHHHHHHHHHHCCHHCCCCCCCHHHHCCCCCCCCCCCCCCCCC
GQHWGLLWSGPQSHQSARLFRDWTDKLTVFADGHDIAADIQADLARRNMPVVDGRIVEIA
CCCCCEEECCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEE
HHTGHITTVNLDTGRNVAVDVLFAHPRNKPSASLHESLGLATVDTPTGIVLKVDERRQTS
ECCCCEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHCCEEEECCCCCEEEEECCCCCCC
IPGIYAAGDLATPFLPSVTQASSQGAMAGIFAQQSMVV
CCCEEECCCCCCCCCCCHHHCCCCCCEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]