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The map label for this gene is yhcV [H]

Identifier: 73538224

GI number: 73538224

Start: 1053363

End: 1053857

Strand: Reverse

Name: yhcV [H]

Synonym: Reut_B4395

Alternate gene names: 73538224

Gene position: 1053857-1053363 (Counterclockwise)

Preceding gene: 73538225

Following gene: 73538223

Centisome position: 38.66

GC content: 64.85

Gene sequence:

>495_bases
ATGGCCACCCAGATGCAAACGCAGCGTACGCAGCATAGGCGGCAAGCTGCCACGCCCACCTCGTCGCTGCGGCTGCGCGA
CGTGATGACCCCCAATCCCCAGTACATCACGCCTGACTGCACACTGCAGGAAGCCGCAAAACTCATGGACGACCTCAATG
TCGGCACGCTACCCGTGTGCGTCGACGGACAGTTGCGCGGGATGGTGACGGACCGCGACATCACGTGCCGGTGCATCGCC
GTGGGCAAGGACCCGCAGACCCGGATCGTCGACGCAATGTCCGAGCGGCCGCTGTGGTGCCGCGATGACGACACCATCGA
CGATGCGCTCGCAAAGATGGCCGAACGGCAGATTCGCCGTGTGCCCGTGATCGACAAGGACGACAGGCTGGTCGGCATTG
TGTCGCTCGGCGATATCGCGACCAAGTCTGGCGACATCGCCAAGGCCGGCGATACGCTGACCGAGGTCTCGAACCCGTCC
GAGCCGGACCGCTGA

Upstream 100 bases:

>100_bases
CGTTGCAATGCACATCCGTGCCTCGAGCCGCCCCAAGTGACGGTGACGGCGATCCGACGACCAGACAAAGCGCAGGCAAA
GCGCAGACATGGAGAACCAG

Downstream 100 bases:

>100_bases
TAGCGCCCGGGCTAATCGAATCCCTGAAAGCGGGAATGCCGGGAATAACGCCTCGCGTCTCGCGCCGGAGGATCGCAGGC
GAGCTGTGGCGCGCGATCTG

Product: hypothetical protein

Products: H+; Nicotinamide adenine dinucleotide - reduced; Xanthosine 5'-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MATQMQTQRTQHRRQAATPTSSLRLRDVMTPNPQYITPDCTLQEAAKLMDDLNVGTLPVCVDGQLRGMVTDRDITCRCIA
VGKDPQTRIVDAMSERPLWCRDDDTIDDALAKMAERQIRRVPVIDKDDRLVGIVSLGDIATKSGDIAKAGDTLTEVSNPS
EPDR

Sequences:

>Translated_164_residues
MATQMQTQRTQHRRQAATPTSSLRLRDVMTPNPQYITPDCTLQEAAKLMDDLNVGTLPVCVDGQLRGMVTDRDITCRCIA
VGKDPQTRIVDAMSERPLWCRDDDTIDDALAKMAERQIRRVPVIDKDDRLVGIVSLGDIATKSGDIAKAGDTLTEVSNPS
EPDR
>Mature_163_residues
ATQMQTQRTQHRRQAATPTSSLRLRDVMTPNPQYITPDCTLQEAAKLMDDLNVGTLPVCVDGQLRGMVTDRDITCRCIAV
GKDPQTRIVDAMSERPLWCRDDDTIDDALAKMAERQIRRVPVIDKDDRLVGIVSLGDIATKSGDIAKAGDTLTEVSNPSE
PDR

Specific function: GMP biosynthesis from IMP; first step. [C]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644 [H]

Pfam domain/function: PF00571 CBS [H]

EC number: 1.1.1.205 [C]

Molecular weight: Translated: 18151; Mature: 18020

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQMQTQRTQHRRQAATPTSSLRLRDVMTPNPQYITPDCTLQEAAKLMDDLNVGTLPVC
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHCCCCCEEEE
VDGQLRGMVTDRDITCRCIAVGKDPQTRIVDAMSERPLWCRDDDTIDDALAKMAERQIRR
ECCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHH
VPVIDKDDRLVGIVSLGDIATKSGDIAKAGDTLTEVSNPSEPDR
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure 
ATQMQTQRTQHRRQAATPTSSLRLRDVMTPNPQYITPDCTLQEAAKLMDDLNVGTLPVC
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHCCCCCEEEE
VDGQLRGMVTDRDITCRCIAVGKDPQTRIVDAMSERPLWCRDDDTIDDALAKMAERQIRR
ECCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHH
VPVIDKDDRLVGIVSLGDIATKSGDIAKAGDTLTEVSNPSEPDR
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; IMP; Nicotinamide adenine dinucleotide [C]

Specific reaction: H2O + IMP + Nicotinamide adenine dinucleotide --> H+ + Nicotinamide adenine dinucleotide - reduced + Xanthosine 5'-phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]