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The map label for this gene is yfbG [C]

Identifier: 73538220

GI number: 73538220

Start: 1047924

End: 1048976

Strand: Direct

Name: yfbG [C]

Synonym: Reut_B4391

Alternate gene names: 73538220

Gene position: 1047924-1048976 (Clockwise)

Preceding gene: 73538219

Following gene: 73538221

Centisome position: 38.44

GC content: 64.29

Gene sequence:

>1053_bases
ATGCGGGAAGCCGATCGCAAGCGCGTCCTGGTAACCGGAGGTGCCGGGTTTCTGGGTTCGCACCTGTGCGAGCGCCTGGT
CGAACTCGGCCACGATGTACTTTGTGTTGATAATTTCTACACGGGCTCGAAGGAGAACATCTCCCACCTGTTGCCTCTCT
ACAATTTCGAGCTGCTGCGCCACGACGTGACGTTCCCGCTTTATGTCGAGGTGGACCAGATCTACAACCTCGCGTGCCCG
GCATCGCCCGTCCACTACCAGAGCGATCCGGTGCAGACCACCAAGACCAGCGTGCATGGCGCGATCAACATGCTCGGACT
GGCCAAGCGGGTGAAAGCGCGCATCCTGCAGGCATCCACCAGCGAGGTCTACGGCGACCCGGACAACCATCCGCAGCGCG
AAAGCTACTGGGGCCATGTCAACCCTGTCGGGCGGCGCGCCTGCTACGACGAGGGCAAGCGCTGCGCCGAAACGCTGTTC
ATGGATTACCACCGCCAGCACGGCGTCGATGTGCGTATTGCACGCATTTTCAACACCTACGGGCCGCGCATGCATCCGGC
CGACGGACGCGTAGTGTCGAACTTCATTTCGCAGGCGCTGGATGGCGAGCCGCTGACGCTCTACGGTGACGGGTCGCAGA
CGCGTTCGTTCTGCTTTGTCGATGATCTCGTCGACGGACTGATGCGGTTGATGGAGTCCGACGCCGCGGCAACGCCCGTG
AATCTCGGCAACCCGTGCGAATGCACGATGCATGCAATCGCGAACGAGATCCTGCAGGCGACCGGGTCGGCTTCGGCCAT
CGAGACGCGCCCGCTGCCGGAGGACGATCCGCGCCAGCGCTGCCCCGACATCACACTGGCACGCACGTTGCTGCAGTGGA
ACCCGGCGACAACCTTGACGGAGGGCCTGCGGCTGACAGTGGCGTATTTCGTCTCGCGTCGGGCCGAACGCGCGCGGCGG
CAGAAGGCCGCCAATCGCGCCGCGCCACTGGCGAAGTCCGCGGAAGCATCGCGGCAGGCGCCACAGCCATCGCCCGCTCC
CGACGTCTCCTGA

Upstream 100 bases:

>100_bases
AGCGTCGCGCGAACCATGGAACAGGTCTACGCGCGCGTCATGCGTGCCGAGCGCCCGGCACGCCGGGTCGCGGCCTGAAC
GTAACAACAAGGAGCCAGCC

Downstream 100 bases:

>100_bases
AGCCTTCAAGCCTTCCAAGGAACGATGCCGACTTCCCATGCTCCGGAGCGGATGACGATCCTCTCCCCGCACCTCGACGA
CGCGGTCTTCAGCTGCGGGT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MREADRKRVLVTGGAGFLGSHLCERLVELGHDVLCVDNFYTGSKENISHLLPLYNFELLRHDVTFPLYVEVDQIYNLACP
ASPVHYQSDPVQTTKTSVHGAINMLGLAKRVKARILQASTSEVYGDPDNHPQRESYWGHVNPVGRRACYDEGKRCAETLF
MDYHRQHGVDVRIARIFNTYGPRMHPADGRVVSNFISQALDGEPLTLYGDGSQTRSFCFVDDLVDGLMRLMESDAAATPV
NLGNPCECTMHAIANEILQATGSASAIETRPLPEDDPRQRCPDITLARTLLQWNPATTLTEGLRLTVAYFVSRRAERARR
QKAANRAAPLAKSAEASRQAPQPSPAPDVS

Sequences:

>Translated_350_residues
MREADRKRVLVTGGAGFLGSHLCERLVELGHDVLCVDNFYTGSKENISHLLPLYNFELLRHDVTFPLYVEVDQIYNLACP
ASPVHYQSDPVQTTKTSVHGAINMLGLAKRVKARILQASTSEVYGDPDNHPQRESYWGHVNPVGRRACYDEGKRCAETLF
MDYHRQHGVDVRIARIFNTYGPRMHPADGRVVSNFISQALDGEPLTLYGDGSQTRSFCFVDDLVDGLMRLMESDAAATPV
NLGNPCECTMHAIANEILQATGSASAIETRPLPEDDPRQRCPDITLARTLLQWNPATTLTEGLRLTVAYFVSRRAERARR
QKAANRAAPLAKSAEASRQAPQPSPAPDVS
>Mature_350_residues
MREADRKRVLVTGGAGFLGSHLCERLVELGHDVLCVDNFYTGSKENISHLLPLYNFELLRHDVTFPLYVEVDQIYNLACP
ASPVHYQSDPVQTTKTSVHGAINMLGLAKRVKARILQASTSEVYGDPDNHPQRESYWGHVNPVGRRACYDEGKRCAETLF
MDYHRQHGVDVRIARIFNTYGPRMHPADGRVVSNFISQALDGEPLTLYGDGSQTRSFCFVDDLVDGLMRLMESDAAATPV
NLGNPCECTMHAIANEILQATGSASAIETRPLPEDDPRQRCPDITLARTLLQWNPATTLTEGLRLTVAYFVSRRAERARR
QKAANRAAPLAKSAEASRQAPQPSPAPDVS

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=321, Percent_Identity=58.5669781931464, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI7657641, Length=323, Percent_Identity=26.9349845201238, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1788589, Length=346, Percent_Identity=25.1445086705202, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=24.4117647058824, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=25.748502994012, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994969, Length=360, Percent_Identity=23.6111111111111, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=323, Percent_Identity=56.3467492260062, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17568069, Length=343, Percent_Identity=27.1137026239067, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=332, Percent_Identity=26.8072289156627, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=334, Percent_Identity=24.251497005988, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=301, Percent_Identity=24.2524916943522, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356223, Length=322, Percent_Identity=57.7639751552795, Blast_Score=393, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38786; Mature: 38786

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREADRKRVLVTGGAGFLGSHLCERLVELGHDVLCVDNFYTGSKENISHLLPLYNFELLR
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
HDVTFPLYVEVDQIYNLACPASPVHYQSDPVQTTKTSVHGAINMLGLAKRVKARILQAST
HCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEVYGDPDNHPQRESYWGHVNPVGRRACYDEGKRCAETLFMDYHRQHGVDVRIARIFNTY
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHC
GPRMHPADGRVVSNFISQALDGEPLTLYGDGSQTRSFCFVDDLVDGLMRLMESDAAATPV
CCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCC
NLGNPCECTMHAIANEILQATGSASAIETRPLPEDDPRQRCPDITLARTLLQWNPATTLT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHH
EGLRLTVAYFVSRRAERARRQKAANRAAPLAKSAEASRQAPQPSPAPDVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MREADRKRVLVTGGAGFLGSHLCERLVELGHDVLCVDNFYTGSKENISHLLPLYNFELLR
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
HDVTFPLYVEVDQIYNLACPASPVHYQSDPVQTTKTSVHGAINMLGLAKRVKARILQAST
HCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEVYGDPDNHPQRESYWGHVNPVGRRACYDEGKRCAETLFMDYHRQHGVDVRIARIFNTY
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHC
GPRMHPADGRVVSNFISQALDGEPLTLYGDGSQTRSFCFVDDLVDGLMRLMESDAAATPV
CCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCC
NLGNPCECTMHAIANEILQATGSASAIETRPLPEDDPRQRCPDITLARTLLQWNPATTLT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHH
EGLRLTVAYFVSRRAERARRQKAANRAAPLAKSAEASRQAPQPSPAPDVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]