| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
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The map label for this gene is cpg2 [H]
Identifier: 73538198
GI number: 73538198
Start: 1025312
End: 1026586
Strand: Reverse
Name: cpg2 [H]
Synonym: Reut_B4369
Alternate gene names: 73538198
Gene position: 1026586-1025312 (Counterclockwise)
Preceding gene: 73538199
Following gene: 73538196
Centisome position: 37.66
GC content: 67.37
Gene sequence:
>1275_bases ATGCCGCTTGCCCTTCGTCCGTTCGCCGTTGCCGCTGCCGCGGCCATGACCCTTGGTGCCACCGGCTCCGCGCAGGCCGC CGGCAATGCCGGTAACGCCGATACCGCGCTGCTGGATGCCGCGCGCGCCGCGCAGCCCGCGGTCGTGCAATCGCTCAAGG AGATGGTGTCGATCGAATCCGGCAGTGCCAACGCCGAAGGCCTTGCGCAGATGGCCAGCTATACCGAGCGCCGTCTGCAG GCGCTGGGTGCGCAGGTGGAACGGCTGCCGGTTGCGAAGGGGCCGGGCACGATGATCCGTGGCACGCTCCAGGGCACGGG CAAGGCGCGCATCATGCTGATCGCCCACATGGATACGGTCTACCCGGCTGGCATCCTCGCCACGCAGCCCATACGCGAAG ACGGCAACCGGCTCTACGGGCCGGGCATTGCCGACGACAAGGGCGGCATTGCGCTGATCGTCCATTCGCTGGAGATACTC AAGCAGCGCGGCTGGCGCGATTATGCGCAGATCACCGTGCTGTTCAACCCGGATGAGGAAATCGGTTCGGGCGGCTCGGG CCGGACGATTGCCACACTGGCCGACCAGCATGACGTGGTGCTCTCCTTCGAGCCCAACGCGGCGAAGGCGGTTGCCAGAC AAGAATCGCTGCTGCTCGGTGCCAGTGGCACCGCCAGCGCCGTCATGCATGTGCACGGGCGCGCGTCGCATGCCGGCGCG GCACCGGACCTTGGCCGCAATGCCTTGCTGGAACTCGCTTACCAGCTTCAGCAGACGCGTGACACGGCAAAGCTGGTTCC GGGCTCGCAACTCAACTGGACGCAGGCGAGCGCGGGCCAGGTGCGGAACCAGATTCCCGATAGCGCGGTTGCCTACGCCG ATGTCCGTATCAGCGCCGACGGCGCCGACGAGAAGCTGCGCGCCGCGTTGCAGGAGAAGGTCAATGCCAGCCAACTGGTC CCGGACACGCGCACCACGGTGACCATGGAAGCAGGGCGGCCGCCTTACGTTGCCGACGCGCGCGGGCGCGCACTGGCACA GCGTGCCCAGGAAATCTATGCCGAGCTCGATGGCCGCCGGCTGGGGCTCGTCGAAGGTACCGGTGGCGGCACCGATGCGG GCTTTGCGTCGCGATCGGGCAAGGCCGTGGTGGTTGAAAGCTTCGGGCTGTCAGGCTTTGGCTATCACGCCCGCGACGAG TACATCGAGCTCGATTCCATCGTGCCGCGCCTGTACCTCGTGACGCGGATGCTGCAGGAGATCGGCCGGCGCTGA
Upstream 100 bases:
>100_bases ACCGGCCGCCCGCGCAGACTTTGGCGTCCGCCATCTTCCCAGTTCGTCAGGCAACGGCTAGCATCGGCAGGTTTGTGATG ACCTGCCGAGAGGAGACTTC
Downstream 100 bases:
>100_bases GGTTGCATAAATGCTGAAAAGCGGCGCCCGCCCCGCTATGGGCGCCGCGGCAGCCTCACGCCGAACGCCGTCTCTGTACT ATCCGAACGCACGTAGATGG
Product: glutamate carboxypeptidase
Products: NA
Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]
Number of amino acids: Translated: 424; Mature: 423
Protein sequence:
>424_residues MPLALRPFAVAAAAAMTLGATGSAQAAGNAGNADTALLDAARAAQPAVVQSLKEMVSIESGSANAEGLAQMASYTERRLQ ALGAQVERLPVAKGPGTMIRGTLQGTGKARIMLIAHMDTVYPAGILATQPIREDGNRLYGPGIADDKGGIALIVHSLEIL KQRGWRDYAQITVLFNPDEEIGSGGSGRTIATLADQHDVVLSFEPNAAKAVARQESLLLGASGTASAVMHVHGRASHAGA APDLGRNALLELAYQLQQTRDTAKLVPGSQLNWTQASAGQVRNQIPDSAVAYADVRISADGADEKLRAALQEKVNASQLV PDTRTTVTMEAGRPPYVADARGRALAQRAQEIYAELDGRRLGLVEGTGGGTDAGFASRSGKAVVVESFGLSGFGYHARDE YIELDSIVPRLYLVTRMLQEIGRR
Sequences:
>Translated_424_residues MPLALRPFAVAAAAAMTLGATGSAQAAGNAGNADTALLDAARAAQPAVVQSLKEMVSIESGSANAEGLAQMASYTERRLQ ALGAQVERLPVAKGPGTMIRGTLQGTGKARIMLIAHMDTVYPAGILATQPIREDGNRLYGPGIADDKGGIALIVHSLEIL KQRGWRDYAQITVLFNPDEEIGSGGSGRTIATLADQHDVVLSFEPNAAKAVARQESLLLGASGTASAVMHVHGRASHAGA APDLGRNALLELAYQLQQTRDTAKLVPGSQLNWTQASAGQVRNQIPDSAVAYADVRISADGADEKLRAALQEKVNASQLV PDTRTTVTMEAGRPPYVADARGRALAQRAQEIYAELDGRRLGLVEGTGGGTDAGFASRSGKAVVVESFGLSGFGYHARDE YIELDSIVPRLYLVTRMLQEIGRR >Mature_423_residues PLALRPFAVAAAAAMTLGATGSAQAAGNAGNADTALLDAARAAQPAVVQSLKEMVSIESGSANAEGLAQMASYTERRLQA LGAQVERLPVAKGPGTMIRGTLQGTGKARIMLIAHMDTVYPAGILATQPIREDGNRLYGPGIADDKGGIALIVHSLEILK QRGWRDYAQITVLFNPDEEIGSGGSGRTIATLADQHDVVLSFEPNAAKAVARQESLLLGASGTASAVMHVHGRASHAGAA PDLGRNALLELAYQLQQTRDTAKLVPGSQLNWTQASAGQVRNQIPDSAVAYADVRISADGADEKLRAALQEKVNASQLVP DTRTTVTMEAGRPPYVADARGRALAQRAQEIYAELDGRRLGLVEGTGGGTDAGFASRSGKAVVVESFGLSGFGYHARDEY IELDSIVPRLYLVTRMLQEIGRR
Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]
COG id: COG0624
COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase M20A family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001261 - InterPro: IPR017150 - InterPro: IPR002933 - InterPro: IPR011650 [H]
Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]
EC number: =3.4.17.11 [H]
Molecular weight: Translated: 44497; Mature: 44366
Theoretical pI: Translated: 6.91; Mature: 6.91
Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPLALRPFAVAAAAAMTLGATGSAQAAGNAGNADTALLDAARAAQPAVVQSLKEMVSIES CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC GSANAEGLAQMASYTERRLQALGAQVERLPVAKGPGTMIRGTLQGTGKARIMLIAHMDTV CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCC YPAGILATQPIREDGNRLYGPGIADDKGGIALIVHSLEILKQRGWRDYAQITVLFNPDEE CCCCHHCCCCHHHCCCEEECCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEEEEECCCHH IGSGGSGRTIATLADQHDVVLSFEPNAAKAVARQESLLLGASGTASAVMHVHGRASHAGA HCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCC APDLGRNALLELAYQLQQTRDTAKLVPGSQLNWTQASAGQVRNQIPDSAVAYADVRISAD CCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEECC GADEKLRAALQEKVNASQLVPDTRTTVTMEAGRPPYVADARGRALAQRAQEIYAELDGRR CCHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCE LGLVEGTGGGTDAGFASRSGKAVVVESFGLSGFGYHARDEYIELDSIVPRLYLVTRMLQE EEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH IGRR HCCC >Mature Secondary Structure PLALRPFAVAAAAAMTLGATGSAQAAGNAGNADTALLDAARAAQPAVVQSLKEMVSIES CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC GSANAEGLAQMASYTERRLQALGAQVERLPVAKGPGTMIRGTLQGTGKARIMLIAHMDTV CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEECCCC YPAGILATQPIREDGNRLYGPGIADDKGGIALIVHSLEILKQRGWRDYAQITVLFNPDEE CCCCHHCCCCHHHCCCEEECCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEEEEECCCHH IGSGGSGRTIATLADQHDVVLSFEPNAAKAVARQESLLLGASGTASAVMHVHGRASHAGA HCCCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCC APDLGRNALLELAYQLQQTRDTAKLVPGSQLNWTQASAGQVRNQIPDSAVAYADVRISAD CCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEECC GADEKLRAALQEKVNASQLVPDTRTTVTMEAGRPPYVADARGRALAQRAQEIYAELDGRR CCHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCE LGLVEGTGGGTDAGFASRSGKAVVVESFGLSGFGYHARDEYIELDSIVPRLYLVTRMLQE EEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH IGRR HCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 6396165; 3838935; 9083113 [H]