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The map label for this gene is dnaJ [H]

Identifier: 73538176

GI number: 73538176

Start: 1006578

End: 1007156

Strand: Reverse

Name: dnaJ [H]

Synonym: Reut_B4346

Alternate gene names: 73538176

Gene position: 1007156-1006578 (Counterclockwise)

Preceding gene: 73538178

Following gene: 73538175

Centisome position: 36.94

GC content: 64.42

Gene sequence:

>579_bases
ATGACACTCTATGCGACCCTTGGCGTCGAATCGGACGCCACCTTGGACGAGATCAAGCGCGCCTACCGCCGTGCCGCGAT
GAAGTGGCACCCCGACCGCAACCCCGGCCGCGAGGCCGAGGCACACCTGGCCTTCCAGGAAATCCGCGACGCATACGCCA
TCCTCTCCGATGAGACGCAACGCCGCGTGTACGACGACGTATTCGCGCAGGAAATGCGCCGCTGGCAAGCGGAACACGCC
GCGCAGGAAGAACAGGAGCAAGCGGCGCAGCGCGAAGCGCAACGCCTTGCGCAGGAACACTACGAAAAGATGGTCGTCAT
CGCGATGCGTTTCGCCGACGACGGCCACAACCGTGACGTCCTCTTCGGCGTGCTGCTTGGCCACGATTGCGAGGCAGAAC
TGGCGGGGCGAATCGCCGACAGCGTGTGGGCCTTGCAGGAGTCGCGCAAGGCACAACCGGAGGCTGAAGAAGAGGCTGCA
CCGGAGATCGGGCCTGAGGAAGATGCGGCGAAGCGCACCAGCCGTCACCCCGGGGCTTTCGAGTCGTTCTGGCAGGGCCT
GTTCGGAATTCGTACATAG

Upstream 100 bases:

>100_bases
TCGGAGATGCGCTGAATTGCAGCGCCATGGGCGCGCAAGCGGCGTTTGCGAGGCACTGCCATGCTAGGATGAACGCCAAC
GCAGCAGTCTCCCCCGCACC

Downstream 100 bases:

>100_bases
CGCGTGCGCTGTCTGAGCGGGGCGTGGGCCCGCGACGCCTTTCGCATTCCCTCCGCGCATTTCCTTTTCCAGGTCCTGCA
ACGGGCGAGGGCATTGCAAT

Product: heat shock protein DnaJ, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTLYATLGVESDATLDEIKRAYRRAAMKWHPDRNPGREAEAHLAFQEIRDAYAILSDETQRRVYDDVFAQEMRRWQAEHA
AQEEQEQAAQREAQRLAQEHYEKMVVIAMRFADDGHNRDVLFGVLLGHDCEAELAGRIADSVWALQESRKAQPEAEEEAA
PEIGPEEDAAKRTSRHPGAFESFWQGLFGIRT

Sequences:

>Translated_192_residues
MTLYATLGVESDATLDEIKRAYRRAAMKWHPDRNPGREAEAHLAFQEIRDAYAILSDETQRRVYDDVFAQEMRRWQAEHA
AQEEQEQAAQREAQRLAQEHYEKMVVIAMRFADDGHNRDVLFGVLLGHDCEAELAGRIADSVWALQESRKAQPEAEEEAA
PEIGPEEDAAKRTSRHPGAFESFWQGLFGIRT
>Mature_191_residues
TLYATLGVESDATLDEIKRAYRRAAMKWHPDRNPGREAEAHLAFQEIRDAYAILSDETQRRVYDDVFAQEMRRWQAEHAA
QEEQEQAAQREAQRLAQEHYEKMVVIAMRFADDGHNRDVLFGVLLGHDCEAELAGRIADSVWALQESRKAQPEAEEEAAP
EIGPEEDAAKRTSRHPGAFESFWQGLFGIRT

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI45504382, Length=64, Percent_Identity=50, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI23503241, Length=64, Percent_Identity=43.75, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI17388799, Length=62, Percent_Identity=46.7741935483871, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4885495, Length=62, Percent_Identity=46.7741935483871, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI27151736, Length=64, Percent_Identity=45.3125, Blast_Score=68, Evalue=4e-12,
Organism=Homo sapiens, GI88501736, Length=64, Percent_Identity=45.3125, Blast_Score=68, Evalue=4e-12,
Organism=Homo sapiens, GI21553335, Length=65, Percent_Identity=41.5384615384615, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI56549115, Length=62, Percent_Identity=50, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI201862518, Length=62, Percent_Identity=50, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI201862587, Length=62, Percent_Identity=50, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI47777312, Length=62, Percent_Identity=45.1612903225806, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI68077168, Length=63, Percent_Identity=49.2063492063492, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI68077166, Length=63, Percent_Identity=49.2063492063492, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1786197, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534355, Length=62, Percent_Identity=50, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17568643, Length=67, Percent_Identity=46.2686567164179, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17554644, Length=65, Percent_Identity=50.7692307692308, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507263, Length=62, Percent_Identity=46.7741935483871, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554874, Length=62, Percent_Identity=48.3870967741936, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=62, Percent_Identity=50, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324252, Length=64, Percent_Identity=50, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654066, Length=63, Percent_Identity=50.7936507936508, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24654070, Length=63, Percent_Identity=50.7936507936508, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24654068, Length=63, Percent_Identity=50.7936507936508, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24654072, Length=63, Percent_Identity=50.7936507936508, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17737735, Length=65, Percent_Identity=46.1538461538462, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28574723, Length=65, Percent_Identity=46.1538461538462, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24668523, Length=65, Percent_Identity=46.1538461538462, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161077138, Length=62, Percent_Identity=50, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646562, Length=63, Percent_Identity=50.7936507936508, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646560, Length=63, Percent_Identity=50.7936507936508, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646558, Length=63, Percent_Identity=50.7936507936508, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646556, Length=63, Percent_Identity=50.7936507936508, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357547, Length=63, Percent_Identity=50.7936507936508, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85726398, Length=62, Percent_Identity=48.3870967741936, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658562, Length=64, Percent_Identity=46.875, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658555, Length=64, Percent_Identity=46.875, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24762799, Length=79, Percent_Identity=41.7721518987342, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 21983; Mature: 21852

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLYATLGVESDATLDEIKRAYRRAAMKWHPDRNPGREAEAHLAFQEIRDAYAILSDETQ
CEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRVYDDVFAQEMRRWQAEHAAQEEQEQAAQREAQRLAQEHYEKMVVIAMRFADDGHNRDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LFGVLLGHDCEAELAGRIADSVWALQESRKAQPEAEEEAAPEIGPEEDAAKRTSRHPGAF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHCCCCCHH
ESFWQGLFGIRT
HHHHHHHHHCCC
>Mature Secondary Structure 
TLYATLGVESDATLDEIKRAYRRAAMKWHPDRNPGREAEAHLAFQEIRDAYAILSDETQ
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRVYDDVFAQEMRRWQAEHAAQEEQEQAAQREAQRLAQEHYEKMVVIAMRFADDGHNRDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LFGVLLGHDCEAELAGRIADSVWALQESRKAQPEAEEEAAPEIGPEEDAAKRTSRHPGAF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHCCCCCHH
ESFWQGLFGIRT
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA