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The map label for this gene is yfdZ [H]

Identifier: 73538098

GI number: 73538098

Start: 924777

End: 926033

Strand: Reverse

Name: yfdZ [H]

Synonym: Reut_B4268

Alternate gene names: 73538098

Gene position: 926033-924777 (Counterclockwise)

Preceding gene: 73538099

Following gene: 73538096

Centisome position: 33.97

GC content: 62.69

Gene sequence:

>1257_bases
ATGACTGCCAGCTCTGGCAAGCGCCGCTTTGCGCGCATCGATCGCCTTCCCCCGTACGTTTTCAATATCACCGCCGAGTT
GAAGATGGCCGCCCGCCGCCGTGGCGAGGACATCATCGACATGAGCATGGGCAACCCCGACGGGGCCACGCCGCCGCATA
TCGTCGCCAAGCTGGTGGAAGCCGCGCAGCGCCCCGACACGCATGGCTATTCCGCGTCGAAGGGTATTCCGCGACTGCGC
CGTGCGATTTCGCATTGGTACCGCGAACGCTATGACGTGGAGATTGACCCGGATACCGAGGCCATCGTCACGATCGGCTC
CAAGGAAGGGCTCGCGCACCTGATGCTCGCCACGCTGGATCGTGGCGACAGCGTGCTGGTGCCGGACCCGAGCTATCCGA
TCCACATCTATGGCGCGGTGATCGCCGGTGCGGATATCCGCTCGGTGCCGCTGGTGCCCGGCGTCGATTTCTTCGCGGAA
CTGGAGCGCACGATTCGCGGCAGCTATCCAAAGCCGAAGATGATCGTGCTGGGGTTCCCGTCGAACCCGACCGCGCAATG
CGTGGAGCTGGATTTCTTCGAGCGCGTGATCGCGCTGGCGCGCAAGCATGACATCTTCGTGGTCCATGACCTGGCTTATG
CCGACATCGTCTTCGATGGCTGGAAGGCGCCGTCGATCATGCAGGTGCCCGGAGCGAAGGACATCGCAGTGGAGTTCTTC
ACGCTTTCCAAGAGCTACAACATGGCGGGATGGCGCATCGGCTTCATGGTCGGCAACCCCGATCTCGTCGCCGCGCTCAC
GCGCATCAAGAGCTATCACGACTATGGCACGTTCACGCCGGTGCAGATTGCCGCGATTGCCGCGCTGGAAGGGGACCAGG
AATGCGTGAAGGAAATCGCCGCGCACTACCAGTCGCGTCGCGACGTGCTCGCGAAAGGGTTGATCGAGTCGGGCTGGCTG
GTCGACATCCCAAAGGCCTCGATGTACATCTGGGCCCGCATTCCCGAGCCTTATCGCGCGCTGGGTTCGCTGGAATTCGC
CAAACAGCTGCTGGCGAAGGCGAAGGTTTCAGTCTCGCCCGGCATCGGCTTTGGCGACTACGGCGATGAGTACGTGCGCT
TTGCGTTGATCGAGAACGAAGCGCGCATCCGCCAGGCCGTGCGCGGTATCAAGGCGATGTTCCGTGCGGATGGACTGGTC
AAGGTGCCCGCATCAGAACATGCAGACGGGCACGGCAAAGAGAAGGGCAAGGGCTGA

Upstream 100 bases:

>100_bases
GCAATCCCCCCATCCCCGCTAAGATCATTTCCCGGCAGCCGAGACAGCGGTTGCCGACGTCGCTCGGACGGTTCCGGGCG
CTTACGTAAAGGACTCCTTC

Downstream 100 bases:

>100_bases
GCGGGGTGTTGGATCGCCCGCACGCATAGCCGTGCGGGCTAACCTCGCACCTCGCGCCGGAACCGGCTTGGTGCGTGGCC
GGTCCATCGCAAGAACGCCC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTASSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVEAAQRPDTHGYSASKGIPRLR
RAISHWYRERYDVEIDPDTEAIVTIGSKEGLAHLMLATLDRGDSVLVPDPSYPIHIYGAVIAGADIRSVPLVPGVDFFAE
LERTIRGSYPKPKMIVLGFPSNPTAQCVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPVQIAAIAALEGDQECVKEIAAHYQSRRDVLAKGLIESGWL
VDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSPGIGFGDYGDEYVRFALIENEARIRQAVRGIKAMFRADGLV
KVPASEHADGHGKEKGKG

Sequences:

>Translated_418_residues
MTASSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVEAAQRPDTHGYSASKGIPRLR
RAISHWYRERYDVEIDPDTEAIVTIGSKEGLAHLMLATLDRGDSVLVPDPSYPIHIYGAVIAGADIRSVPLVPGVDFFAE
LERTIRGSYPKPKMIVLGFPSNPTAQCVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPVQIAAIAALEGDQECVKEIAAHYQSRRDVLAKGLIESGWL
VDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSPGIGFGDYGDEYVRFALIENEARIRQAVRGIKAMFRADGLV
KVPASEHADGHGKEKGKG
>Mature_417_residues
TASSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVEAAQRPDTHGYSASKGIPRLRR
AISHWYRERYDVEIDPDTEAIVTIGSKEGLAHLMLATLDRGDSVLVPDPSYPIHIYGAVIAGADIRSVPLVPGVDFFAEL
ERTIRGSYPKPKMIVLGFPSNPTAQCVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFFT
LSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPVQIAAIAALEGDQECVKEIAAHYQSRRDVLAKGLIESGWLV
DIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSPGIGFGDYGDEYVRFALIENEARIRQAVRGIKAMFRADGLVK
VPASEHADGHGKEKGKG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=425, Percent_Identity=23.7647058823529, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI56713256, Length=418, Percent_Identity=23.9234449760766, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI95147551, Length=421, Percent_Identity=23.9904988123515, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI169881279, Length=421, Percent_Identity=23.9904988123515, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI169881281, Length=239, Percent_Identity=23.4309623430962, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=405, Percent_Identity=81.2345679012346, Blast_Score=696, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=25.3333333333333, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788627, Length=241, Percent_Identity=29.045643153527, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=318, Percent_Identity=26.1006289308176, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=318, Percent_Identity=26.1006289308176, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=22.8643216080402, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=18.9393939393939, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=349, Percent_Identity=22.6361031518625, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=25.2427184466019, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=25.2427184466019, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=25.2427184466019, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=25.2427184466019, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI18859735, Length=251, Percent_Identity=23.9043824701195, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 46110; Mature: 45978

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVE
CCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
AAQRPDTHGYSASKGIPRLRRAISHWYRERYDVEIDPDTEAIVTIGSKEGLAHLMLATLD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCHHHHHHHHHC
RGDSVLVPDPSYPIHIYGAVIAGADIRSVPLVPGVDFFAELERTIRGSYPKPKMIVLGFP
CCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECC
SNPTAQCVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
CCCCCHHEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPVQIAAIAALEGDQECVKEIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHEEHHHCCCCHHHHHHHH
AHYQSRRDVLAKGLIESGWLVDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSP
HHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
GIGFGDYGDEYVRFALIENEARIRQAVRGIKAMFRADGLVKVPASEHADGHGKEKGKG
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TASSGKRRFARIDRLPPYVFNITAELKMAARRRGEDIIDMSMGNPDGATPPHIVAKLVE
CCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
AAQRPDTHGYSASKGIPRLRRAISHWYRERYDVEIDPDTEAIVTIGSKEGLAHLMLATLD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCHHHHHHHHHC
RGDSVLVPDPSYPIHIYGAVIAGADIRSVPLVPGVDFFAELERTIRGSYPKPKMIVLGFP
CCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECC
SNPTAQCVELDFFERVIALARKHDIFVVHDLAYADIVFDGWKAPSIMQVPGAKDIAVEFF
CCCCCHHEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPDLVAALTRIKSYHDYGTFTPVQIAAIAALEGDQECVKEIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHEEHHHCCCCHHHHHHHH
AHYQSRRDVLAKGLIESGWLVDIPKASMYIWARIPEPYRALGSLEFAKQLLAKAKVSVSP
HHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
GIGFGDYGDEYVRFALIENEARIRQAVRGIKAMFRADGLVKVPASEHADGHGKEKGKG
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]