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The map label for this gene is dasR [H]

Identifier: 73538028

GI number: 73538028

Start: 838513

End: 839301

Strand: Reverse

Name: dasR [H]

Synonym: Reut_B4198

Alternate gene names: 73538028

Gene position: 839301-838513 (Counterclockwise)

Preceding gene: 73538029

Following gene: 73538027

Centisome position: 30.79

GC content: 65.02

Gene sequence:

>789_bases
ATGATTATGGACAGCCCTCGTTCGCCTATGCCCCGTTACCACCAGATCTATGTGGCGTTGCGCCACCAGATCGTCAGCGG
GGTCTATGACAGATCCGGCCTTCCGCCCGAACTCAGGCTGATGGAGCAATACCAGGTGGCCCGCGTGACCGTGCGCCGCG
CCATCATCGAACTGGTCAGGGAGGGGATGGTCTACCGGCGCCCGGGTCAGGGTACCTTTGTGAAGCTTGATCATCCGAGC
CGCGCGGAAAGCCAACCCAGGATTCAGGGCCTCCTGGACAACCTGATCGCCTCGGCCGAGCAGACGTCCGTGCGTCTGAT
CGAGTACGGGCTGCAGCCGTGCACACACGATGCTGCCGCAGGGCTGTCGATGGCCGAGGGGCAGAACGCCTTGCGCGTGG
TGCGCCTGCGCAGTCATCAGGGCAAGCCGGTATCGCTGATCACGACCTATCTGCCGGCCCATTTGTCGCCGTTGCTGACG
CCGGCGGAGCTCGAGCAGCATCCCATGCTGTCGCTGCTGGAAAAAGGCGGCATCCGCATCGGCGCCGCCGAGCAGTCCGT
GTCGAGTTGTCCCGCGGACGCCACGGTGGCCCCATTGCTCGACGAACCCGTAGGGTCCGCGCTGCTGTCAGTGGTGCGCG
TAGTGCGCGATGTCGACGGCTATCCCGTCCAGTGGCTTCATGGCCTGTACCGGCCGCATTGCTATGACTACCGCATGGCG
CTAACGCGCGCGGGCGAGGCAACGACCCGCATCTGGCTGGCCAGCGACATCACGACCGGCCTGCGGTAA

Upstream 100 bases:

>100_bases
CCAGTTTAGGCAACGCAAGCCAGCGTTGGCATGCACTGCCTGTAGTGGTATTGCCGGCGGTCTATGCCGGCATCGGCCTG
ACGCCCTCGGATAACCAAAA

Downstream 100 bases:

>100_bases
CCATTTCCGGGGCAGAAGGGGCGCACAAAATGAGCATTGAACACTCGACACCGTGCACCGGCCGCACCGCGCGTATATAT
GCTGCCAGCGGCGCCAGTCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MIMDSPRSPMPRYHQIYVALRHQIVSGVYDRSGLPPELRLMEQYQVARVTVRRAIIELVREGMVYRRPGQGTFVKLDHPS
RAESQPRIQGLLDNLIASAEQTSVRLIEYGLQPCTHDAAAGLSMAEGQNALRVVRLRSHQGKPVSLITTYLPAHLSPLLT
PAELEQHPMLSLLEKGGIRIGAAEQSVSSCPADATVAPLLDEPVGSALLSVVRVVRDVDGYPVQWLHGLYRPHCYDYRMA
LTRAGEATTRIWLASDITTGLR

Sequences:

>Translated_262_residues
MIMDSPRSPMPRYHQIYVALRHQIVSGVYDRSGLPPELRLMEQYQVARVTVRRAIIELVREGMVYRRPGQGTFVKLDHPS
RAESQPRIQGLLDNLIASAEQTSVRLIEYGLQPCTHDAAAGLSMAEGQNALRVVRLRSHQGKPVSLITTYLPAHLSPLLT
PAELEQHPMLSLLEKGGIRIGAAEQSVSSCPADATVAPLLDEPVGSALLSVVRVVRDVDGYPVQWLHGLYRPHCYDYRMA
LTRAGEATTRIWLASDITTGLR
>Mature_262_residues
MIMDSPRSPMPRYHQIYVALRHQIVSGVYDRSGLPPELRLMEQYQVARVTVRRAIIELVREGMVYRRPGQGTFVKLDHPS
RAESQPRIQGLLDNLIASAEQTSVRLIEYGLQPCTHDAAAGLSMAEGQNALRVVRLRSHQGKPVSLITTYLPAHLSPLLT
PAELEQHPMLSLLEKGGIRIGAAEQSVSSCPADATVAPLLDEPVGSALLSVVRVVRDVDGYPVQWLHGLYRPHCYDYRMA
LTRAGEATTRIWLASDITTGLR

Specific function: Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N- acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790540, Length=239, Percent_Identity=29.7071129707113, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790118, Length=187, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 29060; Mature: 29060

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMDSPRSPMPRYHQIYVALRHQIVSGVYDRSGLPPELRLMEQYQVARVTVRRAIIELVR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EGMVYRRPGQGTFVKLDHPSRAESQPRIQGLLDNLIASAEQTSVRLIEYGLQPCTHDAAA
CCCEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
GLSMAEGQNALRVVRLRSHQGKPVSLITTYLPAHLSPLLTPAELEQHPMLSLLEKGGIRI
CCCHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEE
GAAEQSVSSCPADATVAPLLDEPVGSALLSVVRVVRDVDGYPVQWLHGLYRPHCYDYRMA
ECCHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHH
LTRAGEATTRIWLASDITTGLR
HHHCCCHHEEEEEECCHHCCCC
>Mature Secondary Structure
MIMDSPRSPMPRYHQIYVALRHQIVSGVYDRSGLPPELRLMEQYQVARVTVRRAIIELVR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EGMVYRRPGQGTFVKLDHPSRAESQPRIQGLLDNLIASAEQTSVRLIEYGLQPCTHDAAA
CCCEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
GLSMAEGQNALRVVRLRSHQGKPVSLITTYLPAHLSPLLTPAELEQHPMLSLLEKGGIRI
CCCHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEE
GAAEQSVSSCPADATVAPLLDEPVGSALLSVVRVVRDVDGYPVQWLHGLYRPHCYDYRMA
ECCHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHH
LTRAGEATTRIWLASDITTGLR
HHHCCCHHEEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]