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The map label for this gene is cbiO1 [H]

Identifier: 73538026

GI number: 73538026

Start: 837117

End: 838055

Strand: Reverse

Name: cbiO1 [H]

Synonym: Reut_B4196

Alternate gene names: 73538026

Gene position: 838055-837117 (Counterclockwise)

Preceding gene: 73538027

Following gene: 73538025

Centisome position: 30.74

GC content: 67.52

Gene sequence:

>939_bases
ATGAGGCCGGACATCATGCTGGCTGCCCATGGCCTGAGCTTCCGGCCCGGCGCCCATGCTGTGCTGAGTAATGTCTGGAT
GAATCTCGTTCGCGGGCGCATCACTGCGCTGGTAGGCCCCACCGGAGCGGGCAAATCGGCGCTGCTGGGCATCCTGTCGG
GACAGCTGGCGCCGTGCTCGGGCGCCGTGAAACTGGACGGCCACAACATCACCGGCCTGACACCGCATGTCCTGAACCGG
CTCGGCATATGGAGAGTCGGCCCGGCAGTGGCAAAGCCCGACGTGCGGACCGTGCGCGAGCGCATTGCCAGCGCGGCGCA
GTGGCACGTGCGCGGACATCATGTGGCACTCGCCCAGGCCGATGAAGTGGCACGGTGTCTTGGCCTGGAACCGCAACTGC
ACAAGGCGGCGAACGGCCTGCCACCGGCCGCCCGCAGACGGCTGGCACTGGCTTGCGCGCTGGCAGCCCGGCCCCGGTTG
CTGTTGCTCGACGGCCTGCTGGAAGGTCTGGATGCACGGGACACGGCGGCCATGGCGACTGTCATCCGCAGCCTGTGCGC
GGACGGCGTGACAGTGCTGATGGCCGAGCGCTTCACGCAGGCGGTCTCGAAGCTGGCCCATAACGTGGTGGTGCTCGCCG
GCGGCAGCGTGGTCGCGAGCGGTTCCGCGGACATATTGCGCGACCCCGCCATTGCCCACGCCTGCACGGAGCAAGGCGAT
GCCACGGCGGCGCAGGATCCGGGCATATCGCCAGGCGTATCCCTCCACATAGCCCCGCACATATCCCCACGCAAATCCTT
GCCGCATTCCGGCCACACGGCTGCGAAGCCCGCCGCGACAAAGGCGCAGCACCACCACGACACACCCGTGGGCACTGCCA
CCGCGGGTGAAATCACGTCATCGAAAGAACCAGCATCTTCAACGCGAAACGACCCCTGA

Upstream 100 bases:

>100_bases
TTTTTACGTTGTGCTGGCCCGGTGCCGATGCGGGCCATCGTTGCGGGCCTGCCTGGTGCCTCGTGGAAATGTCCAACGGC
GAAGCCGTCGGGAGCCGGGC

Downstream 100 bases:

>100_bases
TGTCCCTGGATGAGAATACCTTGCAACACCCGAAACGCGATGCGGACATTGAGCACGACCGCTACGCATGGTCCCGGCTC
GCCGAACGGCGCCCGGTCGC

Product: ABC transporter-like protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRPDIMLAAHGLSFRPGAHAVLSNVWMNLVRGRITALVGPTGAGKSALLGILSGQLAPCSGAVKLDGHNITGLTPHVLNR
LGIWRVGPAVAKPDVRTVRERIASAAQWHVRGHHVALAQADEVARCLGLEPQLHKAANGLPPAARRRLALACALAARPRL
LLLDGLLEGLDARDTAAMATVIRSLCADGVTVLMAERFTQAVSKLAHNVVVLAGGSVVASGSADILRDPAIAHACTEQGD
ATAAQDPGISPGVSLHIAPHISPRKSLPHSGHTAAKPAATKAQHHHDTPVGTATAGEITSSKEPASSTRNDP

Sequences:

>Translated_312_residues
MRPDIMLAAHGLSFRPGAHAVLSNVWMNLVRGRITALVGPTGAGKSALLGILSGQLAPCSGAVKLDGHNITGLTPHVLNR
LGIWRVGPAVAKPDVRTVRERIASAAQWHVRGHHVALAQADEVARCLGLEPQLHKAANGLPPAARRRLALACALAARPRL
LLLDGLLEGLDARDTAAMATVIRSLCADGVTVLMAERFTQAVSKLAHNVVVLAGGSVVASGSADILRDPAIAHACTEQGD
ATAAQDPGISPGVSLHIAPHISPRKSLPHSGHTAAKPAATKAQHHHDTPVGTATAGEITSSKEPASSTRNDP
>Mature_312_residues
MRPDIMLAAHGLSFRPGAHAVLSNVWMNLVRGRITALVGPTGAGKSALLGILSGQLAPCSGAVKLDGHNITGLTPHVLNR
LGIWRVGPAVAKPDVRTVRERIASAAQWHVRGHHVALAQADEVARCLGLEPQLHKAANGLPPAARRRLALACALAARPRL
LLLDGLLEGLDARDTAAMATVIRSLCADGVTVLMAERFTQAVSKLAHNVVVLAGGSVVASGSADILRDPAIAHACTEQGD
ATAAQDPGISPGVSLHIAPHISPRKSLPHSGHTAAKPAATKAQHHHDTPVGTATAGEITSSKEPASSTRNDP

Specific function: Part of the ABC transporter complex CbiONQ involved in cobalt import. Responsible for energy coupling to the transport system [H]

COG id: COG0411

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=216, Percent_Identity=26.3888888888889, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27436953, Length=218, Percent_Identity=28.4403669724771, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI31657092, Length=217, Percent_Identity=25.3456221198157, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI171184400, Length=221, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI27477115, Length=218, Percent_Identity=27.0642201834862, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI27262624, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI27262626, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789864, Length=239, Percent_Identity=25.5230125523013, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081782, Length=245, Percent_Identity=27.7551020408163, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786319, Length=211, Percent_Identity=25.5924170616114, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790162, Length=241, Percent_Identity=26.5560165975104, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082268, Length=228, Percent_Identity=30.2631578947368, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081709, Length=230, Percent_Identity=25.2173913043478, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081791, Length=234, Percent_Identity=26.4957264957265, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787792, Length=231, Percent_Identity=25.1082251082251, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787029, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786345, Length=230, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI48994943, Length=259, Percent_Identity=26.2548262548263, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789586, Length=237, Percent_Identity=28.6919831223629, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI48995001, Length=217, Percent_Identity=27.1889400921659, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788897, Length=209, Percent_Identity=26.7942583732057, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790190, Length=204, Percent_Identity=24.5098039215686, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788002, Length=223, Percent_Identity=28.2511210762332, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=247, Percent_Identity=25.9109311740891, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324498, Length=212, Percent_Identity=30.188679245283, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24641565, Length=221, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648314, Length=262, Percent_Identity=25.9541984732824, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI221512771, Length=212, Percent_Identity=24.0566037735849, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666092, Length=245, Percent_Identity=24.8979591836735, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015856
- InterPro:   IPR003593
- InterPro:   IPR022112 [H]

Pfam domain/function: PF00005 ABC_tran; PF12370 CoABC_C [H]

EC number: NA

Molecular weight: Translated: 32208; Mature: 32208

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDIMLAAHGLSFRPGAHAVLSNVWMNLVRGRITALVGPTGAGKSALLGILSGQLAPCS
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCCCCC
GAVKLDGHNITGLTPHVLNRLGIWRVGPAVAKPDVRTVRERIASAAQWHVRGHHVALAQA
CEEEECCCCCCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHH
DEVARCLGLEPQLHKAANGLPPAARRRLALACALAARPRLLLLDGLLEGLDARDTAAMAT
HHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
VIRSLCADGVTVLMAERFTQAVSKLAHNVVVLAGGSVVASGSADILRDPAIAHACTEQGD
HHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCCHHHHHCCHHHHHHHCCCC
ATAAQDPGISPGVSLHIAPHISPRKSLPHSGHTAAKPAATKAQHHHDTPVGTATAGEITS
CCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
SKEPASSTRNDP
CCCCCCCCCCCC
>Mature Secondary Structure
MRPDIMLAAHGLSFRPGAHAVLSNVWMNLVRGRITALVGPTGAGKSALLGILSGQLAPCS
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCCCCC
GAVKLDGHNITGLTPHVLNRLGIWRVGPAVAKPDVRTVRERIASAAQWHVRGHHVALAQA
CEEEECCCCCCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHH
DEVARCLGLEPQLHKAANGLPPAARRRLALACALAARPRLLLLDGLLEGLDARDTAAMAT
HHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
VIRSLCADGVTVLMAERFTQAVSKLAHNVVVLAGGSVVASGSADILRDPAIAHACTEQGD
HHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCCHHHHHCCHHHHHHHCCCC
ATAAQDPGISPGVSLHIAPHISPRKSLPHSGHTAAKPAATKAQHHHDTPVGTATAGEITS
CCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
SKEPASSTRNDP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA