BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is fabG [H]

Identifier: 73538001

GI number: 73538001

Start: 813654

End: 814478

Strand: Direct

Name: fabG [H]

Synonym: Reut_B4170

Alternate gene names: 73538001

Gene position: 813654-814478 (Clockwise)

Preceding gene: 73538000

Following gene: 73538002

Centisome position: 29.85

GC content: 63.39

Gene sequence:

>825_bases
ATGGGAGCACTTGAAGGCAAGGTAGCACTGGTCACCGGTTCGGGTCGCGGCATTGGCAACGCGATCGCACTGCGGCTGGC
CCGCGAAGGCGCACGCCTGGTCATCAACGACCTGGACGCCGAGCCAGCGCAACAGACCGTGGAAGAACTGAAGGCCATGG
GCGTGGACGCCGTGGCCTGCGTCGGCAACGTCGCCGCGCCGGACTTCGCCGAGCGTTTCATTGGCACTGCCATGAACACG
TTCAAGGGCATCGACATCATCGTCAACAACGCCGGCTTCACGTGGGATGACGTGGTGCAAAAGATGAGCGACGAGCAGTG
GTACGCGATCCTCGACTGCCATATGACGGCACCGTTCCGCATCCTGCGCGCGGCTTACCCGCACCTCAAGGCGCTGCACG
CCGCCGACAAGGAAGCGGGCCGCGAGGTGTACCGCAAGATCGTCAATATCTCGTCCACGTCGGGCCTGAACGGCAATGCC
GGGCAGATCAACTACTCGGGCGCCAAGGCTGGCGTGATCGGCATGACGCGTGCCATGGCGCGCGAATGGGGCCGCTTCAA
TGTCAACGTGAACGCGGTTGCGTTCGGGCTCATTCATACGCGGATGACCTCTGCCGATGCCAAGGCGGGTGCCACGGTCA
ATATCGAAGGCCGCGAGATCCGCGTGGGGCTCAATCCGGAGATGCTGAAGACGCACGCACAGCGCAACCCGCTGGGACGT
GGCGGTACGCCTGAGGAAGCTGCGGGTGGCGTCTACCTGTTTTGCTCGCCGGATTCGAACTACATCACGGGCCAGGTAGT
GGCTGTCGCGGGTAACGTGCAGTAA

Upstream 100 bases:

>100_bases
TCCGCCTGGAAATCCAGACCGCCAACCAGTATGGCGAAACCAGAATCCTGGGCGACGCAGTCGTCGCCCTGTAAGACCCA
AACATACTCAGGAGTCACAG

Downstream 100 bases:

>100_bases
CCGCGTTTCCGTTCTGAGAGCGCCTGCCGGCGCTCCGTGCGGCCCTACGGCCTTGGGCGCCACCGATGCGGTATGCAAGG
CCGATTTGTTGTCTGCGCGC

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MGALEGKVALVTGSGRGIGNAIALRLAREGARLVINDLDAEPAQQTVEELKAMGVDAVACVGNVAAPDFAERFIGTAMNT
FKGIDIIVNNAGFTWDDVVQKMSDEQWYAILDCHMTAPFRILRAAYPHLKALHAADKEAGREVYRKIVNISSTSGLNGNA
GQINYSGAKAGVIGMTRAMAREWGRFNVNVNAVAFGLIHTRMTSADAKAGATVNIEGREIRVGLNPEMLKTHAQRNPLGR
GGTPEEAAGGVYLFCSPDSNYITGQVVAVAGNVQ

Sequences:

>Translated_274_residues
MGALEGKVALVTGSGRGIGNAIALRLAREGARLVINDLDAEPAQQTVEELKAMGVDAVACVGNVAAPDFAERFIGTAMNT
FKGIDIIVNNAGFTWDDVVQKMSDEQWYAILDCHMTAPFRILRAAYPHLKALHAADKEAGREVYRKIVNISSTSGLNGNA
GQINYSGAKAGVIGMTRAMAREWGRFNVNVNAVAFGLIHTRMTSADAKAGATVNIEGREIRVGLNPEMLKTHAQRNPLGR
GGTPEEAAGGVYLFCSPDSNYITGQVVAVAGNVQ
>Mature_273_residues
GALEGKVALVTGSGRGIGNAIALRLAREGARLVINDLDAEPAQQTVEELKAMGVDAVACVGNVAAPDFAERFIGTAMNTF
KGIDIIVNNAGFTWDDVVQKMSDEQWYAILDCHMTAPFRILRAAYPHLKALHAADKEAGREVYRKIVNISSTSGLNGNAG
QINYSGAKAGVIGMTRAMAREWGRFNVNVNAVAFGLIHTRMTSADAKAGATVNIEGREIRVGLNPEMLKTHAQRNPLGRG
GTPEEAAGGVYLFCSPDSNYITGQVVAVAGNVQ

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=200, Percent_Identity=37, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI15277342, Length=278, Percent_Identity=33.4532374100719, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI32483357, Length=269, Percent_Identity=31.2267657992565, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI5031737, Length=273, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=28.158844765343, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI40254992, Length=270, Percent_Identity=31.1111111111111, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI126723750, Length=276, Percent_Identity=29.7101449275362, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI10190704, Length=269, Percent_Identity=30.1115241635688, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI126723191, Length=203, Percent_Identity=30.5418719211823, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI33667109, Length=223, Percent_Identity=27.3542600896861, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI66933014, Length=273, Percent_Identity=26.3736263736264, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=246, Percent_Identity=27.2357723577236, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4503301, Length=273, Percent_Identity=25.6410256410256, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI83715985, Length=187, Percent_Identity=27.807486631016, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI40254986, Length=236, Percent_Identity=27.9661016949153, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=271, Percent_Identity=35.4243542435424, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789208, Length=270, Percent_Identity=32.5925925925926, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790717, Length=276, Percent_Identity=30.7971014492754, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082100, Length=269, Percent_Identity=30.1115241635688, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787905, Length=272, Percent_Identity=28.6764705882353, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI87082160, Length=269, Percent_Identity=28.2527881040892, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789378, Length=274, Percent_Identity=27.3722627737226, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788459, Length=270, Percent_Identity=30, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI2367175, Length=274, Percent_Identity=28.1021897810219, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=276, Percent_Identity=23.5507246376812, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=274, Percent_Identity=33.2116788321168, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=35.1758793969849, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=268, Percent_Identity=33.2089552238806, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25147288, Length=269, Percent_Identity=33.8289962825279, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17562910, Length=280, Percent_Identity=31.7857142857143, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=270, Percent_Identity=28.8888888888889, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=278, Percent_Identity=28.7769784172662, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=281, Percent_Identity=29.8932384341637, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=284, Percent_Identity=26.056338028169, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=289, Percent_Identity=29.0657439446367, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=287, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=27.536231884058, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=288, Percent_Identity=28.8194444444444, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=280, Percent_Identity=26.7857142857143, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=285, Percent_Identity=27.719298245614, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=268, Percent_Identity=25.7462686567164, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=281, Percent_Identity=28.8256227758007, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=280, Percent_Identity=27.8571428571429, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=269, Percent_Identity=25.6505576208178, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=286, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=279, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=278, Percent_Identity=27.6978417266187, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=284, Percent_Identity=27.4647887323944, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=265, Percent_Identity=24.9056603773585, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=25.9124087591241, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=210, Percent_Identity=33.8095238095238, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24639444, Length=276, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18859837, Length=198, Percent_Identity=35.8585858585859, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21355319, Length=273, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644339, Length=271, Percent_Identity=27.3062730627306, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=273, Percent_Identity=28.2051282051282, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17737361, Length=210, Percent_Identity=29.5238095238095, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=276, Percent_Identity=26.8115942028986, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=276, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640492, Length=200, Percent_Identity=29.5, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281364892, Length=182, Percent_Identity=27.4725274725275, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644337, Length=275, Percent_Identity=26.5454545454545, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29057; Mature: 28926

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALEGKVALVTGSGRGIGNAIALRLAREGARLVINDLDAEPAQQTVEELKAMGVDAVAC
CCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHH
VGNVAAPDFAERFIGTAMNTFKGIDIIVNNAGFTWDDVVQKMSDEQWYAILDCHMTAPFR
HCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
ILRAAYPHLKALHAADKEAGREVYRKIVNISSTSGLNGNAGQINYSGAKAGVIGMTRAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
REWGRFNVNVNAVAFGLIHTRMTSADAKAGATVNIEGREIRVGLNPEMLKTHAQRNPLGR
HHCCCEEEEEHHEEEEHHHHHHCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHCCCCCC
GGTPEEAAGGVYLFCSPDSNYITGQVVAVAGNVQ
CCCCCHHCCCEEEEECCCCCEEEEEEEEEECCCC
>Mature Secondary Structure 
GALEGKVALVTGSGRGIGNAIALRLAREGARLVINDLDAEPAQQTVEELKAMGVDAVAC
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHH
VGNVAAPDFAERFIGTAMNTFKGIDIIVNNAGFTWDDVVQKMSDEQWYAILDCHMTAPFR
HCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
ILRAAYPHLKALHAADKEAGREVYRKIVNISSTSGLNGNAGQINYSGAKAGVIGMTRAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
REWGRFNVNVNAVAFGLIHTRMTSADAKAGATVNIEGREIRVGLNPEMLKTHAQRNPLGR
HHCCCEEEEEHHEEEEHHHHHHCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHCCCCCC
GGTPEEAAGGVYLFCSPDSNYITGQVVAVAGNVQ
CCCCCHHCCCEEEEECCCCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]