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The map label for this gene is mcl1 [H]

Identifier: 73537979

GI number: 73537979

Start: 787062

End: 788057

Strand: Reverse

Name: mcl1 [H]

Synonym: Reut_B4148

Alternate gene names: 73537979

Gene position: 788057-787062 (Counterclockwise)

Preceding gene: 73537980

Following gene: 73537978

Centisome position: 28.91

GC content: 66.77

Gene sequence:

>996_bases
ATGACCACCGCAACGCATCCGAACGACGCCCTGTTTGCCGGCGAAAAATCCTTCCCGGTGCTGGCCGCCTGCGAGCACTT
CGCCGGCAGCGAAAAGCTGATCGGCAAGGCTATGGACCTGCAGGTCGAGTACGGCCCGGTCTTCGACGTGACCTGCGACT
GCGAAGACGGCGCCGCCGCCGGCCAGGAACGCGAGCACGCCGAGATGGTTGCGCGCATGATCGCCTCGGACCGCAACGTC
CACGGCCGTGCCGGTGCCCGTATCCATGACCCGTCGCATCCGGCTTGGCGCCAGGATGTGGACATCATCGTGAACGGCGC
TGGCGGCCGGCTCGCCTATATCACGGTGCCCAAGGCAACCAACAGCGGGCAGGTCGCGGAAGTCATCCGCTATATCGGCG
ACGTCGCCAAGCGCGCCGGCCTGGACAAGCCCGTGCCGGTGCACGTGCTGATCGAAACCCACGGCGCGTTGCGCGACGTG
TTCCAGATCGCGGAACTGCCCAACATCGAAGTGCTCGACTTCGGCCTGATGGACTTCGTCAGCGGCCACCACGGCGCGAT
TCCGGCCGCCGCCATGCGCAGCCCGGGCCAGTTCGAGCACGCGCTGCTCGTGCGCGCGAAGGCCGACATGGTTGCGGCGG
CACTGGCCAACGGCATCGTGCCGGCGCACAACGTGTGCCTGAACCTGAAGGACGCCGAGGTCATCGCCAGCGACGCGTGC
CGTGCACGCAACGAGTTCGGCTTCCTGCGCATGTGGAGCATCTATCCGGCGCAGATCCAGCCGATCGTCAACGCCATGCG
GCCGGACTTCACCGAAGTGGAAGATGCCGCCGGCATCCTGGTGGCCGCGCAGGACGCCGACTGGGGCCCCATCCAGTACA
AGGGCGAACTGCACGACCGCGCCACCTACCGCTACTTCTGGGAAGTGCTGCAGAAGGCGAAGGTGACCGGCATGGCGGTG
CCGGCCGAAGCGGAGCGGCGCTTTTTTGTCAACTGA

Upstream 100 bases:

>100_bases
CGTGCTGGACCTCGACTACACCATCGCCATCCCGAAACGCCAGCGGTAAGCCCCACGCGCGGCCTGCCTCAATGCACATC
ACTTATCAGCGAGACAAGAC

Downstream 100 bases:

>100_bases
CTTCGCCAACTGAAGGCGCAGGAGCGGGACCGCACCGGCATCGTAAAATGTGCACACCCTCCGATTTCCCCCCCCGCCGC
CATGACCGCCGCGCCCCTGA

Product: putative citrate lyase

Products: NA

Alternate protein names: (3S)-malyl-CoA/beta-methylmalyl-CoA lyase; L-malyl-CoA/beta-methylmalyl-CoA lyase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTTATHPNDALFAGEKSFPVLAACEHFAGSEKLIGKAMDLQVEYGPVFDVTCDCEDGAAAGQEREHAEMVARMIASDRNV
HGRAGARIHDPSHPAWRQDVDIIVNGAGGRLAYITVPKATNSGQVAEVIRYIGDVAKRAGLDKPVPVHVLIETHGALRDV
FQIAELPNIEVLDFGLMDFVSGHHGAIPAAAMRSPGQFEHALLVRAKADMVAAALANGIVPAHNVCLNLKDAEVIASDAC
RARNEFGFLRMWSIYPAQIQPIVNAMRPDFTEVEDAAGILVAAQDADWGPIQYKGELHDRATYRYFWEVLQKAKVTGMAV
PAEAERRFFVN

Sequences:

>Translated_331_residues
MTTATHPNDALFAGEKSFPVLAACEHFAGSEKLIGKAMDLQVEYGPVFDVTCDCEDGAAAGQEREHAEMVARMIASDRNV
HGRAGARIHDPSHPAWRQDVDIIVNGAGGRLAYITVPKATNSGQVAEVIRYIGDVAKRAGLDKPVPVHVLIETHGALRDV
FQIAELPNIEVLDFGLMDFVSGHHGAIPAAAMRSPGQFEHALLVRAKADMVAAALANGIVPAHNVCLNLKDAEVIASDAC
RARNEFGFLRMWSIYPAQIQPIVNAMRPDFTEVEDAAGILVAAQDADWGPIQYKGELHDRATYRYFWEVLQKAKVTGMAV
PAEAERRFFVN
>Mature_330_residues
TTATHPNDALFAGEKSFPVLAACEHFAGSEKLIGKAMDLQVEYGPVFDVTCDCEDGAAAGQEREHAEMVARMIASDRNVH
GRAGARIHDPSHPAWRQDVDIIVNGAGGRLAYITVPKATNSGQVAEVIRYIGDVAKRAGLDKPVPVHVLIETHGALRDVF
QIAELPNIEVLDFGLMDFVSGHHGAIPAAAMRSPGQFEHALLVRAKADMVAAALANGIVPAHNVCLNLKDAEVIASDACR
ARNEFGFLRMWSIYPAQIQPIVNAMRPDFTEVEDAAGILVAAQDADWGPIQYKGELHDRATYRYFWEVLQKAKVTGMAVP
AEAERRFFVN

Specific function: Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to beta-methylmalyl-CoA [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.24 [H]

Molecular weight: Translated: 35973; Mature: 35842

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTATHPNDALFAGEKSFPVLAACEHFAGSEKLIGKAMDLQVEYGPVFDVTCDCEDGAAA
CCCCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHCCEEEEEEECCCEEEEEECCCCCCCC
GQEREHAEMVARMIASDRNVHGRAGARIHDPSHPAWRQDVDIIVNGAGGRLAYITVPKAT
CCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCEEEEEEECCCC
NSGQVAEVIRYIGDVAKRAGLDKPVPVHVLIETHGALRDVFQIAELPNIEVLDFGLMDFV
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEECCHHHHH
SGHHGAIPAAAMRSPGQFEHALLVRAKADMVAAALANGIVPAHNVCLNLKDAEVIASDAC
CCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHEEEECCHHHHHHHHHH
RARNEFGFLRMWSIYPAQIQPIVNAMRPDFTEVEDAAGILVAAQDADWGPIQYKGELHDR
HHHCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCHH
ATYRYFWEVLQKAKVTGMAVPAEAERRFFVN
HHHHHHHHHHHHHHHCCEECCCCCCCCCCCC
>Mature Secondary Structure 
TTATHPNDALFAGEKSFPVLAACEHFAGSEKLIGKAMDLQVEYGPVFDVTCDCEDGAAA
CCCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHCCEEEEEEECCCEEEEEECCCCCCCC
GQEREHAEMVARMIASDRNVHGRAGARIHDPSHPAWRQDVDIIVNGAGGRLAYITVPKAT
CCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCEEEEEEECCCC
NSGQVAEVIRYIGDVAKRAGLDKPVPVHVLIETHGALRDVFQIAELPNIEVLDFGLMDFV
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEECCHHHHH
SGHHGAIPAAAMRSPGQFEHALLVRAKADMVAAALANGIVPAHNVCLNLKDAEVIASDAC
CCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHEEEECCHHHHHHHHHH
RARNEFGFLRMWSIYPAQIQPIVNAMRPDFTEVEDAAGILVAAQDADWGPIQYKGELHDR
HHHCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCHH
ATYRYFWEVLQKAKVTGMAVPAEAERRFFVN
HHHHHHHHHHHHHHHCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA