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The map label for this gene is ydcR [H]

Identifier: 73537927

GI number: 73537927

Start: 739823

End: 741262

Strand: Direct

Name: ydcR [H]

Synonym: Reut_B4094

Alternate gene names: 73537927

Gene position: 739823-741262 (Clockwise)

Preceding gene: 73537926

Following gene: 73537928

Centisome position: 27.14

GC content: 63.82

Gene sequence:

>1440_bases
GTGAAACTCTATGAAAAACTGGCTGCCGACATCGAAGCGCTGGTGAAGCAGGGGGTGTTGCTGCCCGGCGAGCGGATTCC
GTCCGTGCGCCAGGCCAGCCAGCACCACCGCATGAGCATCACCACGGTGATCCGGGCCTATGTGCTGCTGGAAAGCCGCG
GCATCATCGAAAGCCGGCCGCAATCCGGCTATTTCGTGCGTCCGCGTTCCGGAGAGACCGCGGTCGAGTTGCTGCCGTCG
CGGCCAAGCGCCAAGCCTTCCGCGGTCGACGTCAGCGCACTGGTGCTGTCCACACTGCGCTCGATCCGCTCGGACGACGC
CGTCCCGCTGGGCTCACCCTATCCCGATGCCGCGCTGTTCCCGTGGCAACGCATCAACCAGTACGCGAACAATATCGCGC
GGCGCTATGCCAAGTGGACCATGCTGGACGATCTGCCGCCGGGCAGCCCTGAGCTGATCCGTCAGATTTCCCGCCGCTAC
CTGGAGAACGGCTACGCGGTAAACCCGAACGAGCTGATCGTCACGATCGGCGCCACCGAGGCCATCAACCTCTGTCTGCA
GGCCGTGGCAAAGCCCGGCGACACGATCGCGGTGGAGTCGCCGACTTTCTATGCGATGCTCCACGCGATCGAGCGGCTGG
GCATGCGCGCGATCGAAGTCGCGACCGACCCGGTCGAGGGCATCGACATTGACGCGCTGGCACGGCTGATCGACGAGAAA
AACGTCGCCGCCTGCATGGTCATGCCCAATTTCCAGAATCCGCTCGGCTTCCAGATGCCCGACGAGAAGAAGCGCGCGCT
GGTGGAAATGCTCACGAGCAAGGACATCCCTGTCATCGAGAATGACGTCTATGGCGAGCTGTACTATGGCGAGGCCCATC
CGAGTTCGCTCAAGGCGTTCGACACCGCCGGCATCGTGCTGCACTGCTCGTCGTTTTCCAAGACGCTGACCAACGCCTAC
CGCATCGGCTGGGCGCTGCCGGGCCGCTACCGCGGCGCCGTCGAGCGGCTCAAGTTCCTGAACACGCTGACCACGCCAGC
CATCCCGCAACTGGCGATCGCCGAGTTCCTGAAGAACGACGGCTACGACTTCCACCTGCGGCGCGTGCGCAAGGCCTATG
CGCAGCAGGCCAGCATCATGGCGGCTACGGTGCGCAGGTTTTTCCCGGAGGGCACGACCACATCGCGTCCGGCCGGCGGC
TATGTCCTGTGGGTGCAGCTTCCCGAAGGTATCGATGCCATGGAGATGTACCACGCGGCGCTGGAACACCGTATTACCGT
TGCGCCGGGGCATATGTTTGCACCTGGCGCGACCTACGACAACTGCATCCGGCTGAACTACAGCGCTGAATGGTCGCCAA
GTATCGAATCGGCCGTCCAGACGTTGGGCAAGGTTGCCACGCACCTGCTTGCCAAGCGGTCGAGCGGGCGAGGAGAGTAA

Upstream 100 bases:

>100_bases
TCTCCATCGTTGGCTTGGCTAAGGACTGCCTGCGGACGGAGACCCGGCGCCCAGGTGCCCGGGAAGGCGCAACCAGATCG
GCCAGCGAGGGGAGCGCGGC

Downstream 100 bases:

>100_bases
ACGCGATGTCTGATCCCGGCAACGAACAGAACGGCGACGGCATCGATCCCGCCATTGTGGAAGTCCTGCTCGTCCTGCGG
GAGGCCGGCATCGAGAACGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MKLYEKLAADIEALVKQGVLLPGERIPSVRQASQHHRMSITTVIRAYVLLESRGIIESRPQSGYFVRPRSGETAVELLPS
RPSAKPSAVDVSALVLSTLRSIRSDDAVPLGSPYPDAALFPWQRINQYANNIARRYAKWTMLDDLPPGSPELIRQISRRY
LENGYAVNPNELIVTIGATEAINLCLQAVAKPGDTIAVESPTFYAMLHAIERLGMRAIEVATDPVEGIDIDALARLIDEK
NVAACMVMPNFQNPLGFQMPDEKKRALVEMLTSKDIPVIENDVYGELYYGEAHPSSLKAFDTAGIVLHCSSFSKTLTNAY
RIGWALPGRYRGAVERLKFLNTLTTPAIPQLAIAEFLKNDGYDFHLRRVRKAYAQQASIMAATVRRFFPEGTTTSRPAGG
YVLWVQLPEGIDAMEMYHAALEHRITVAPGHMFAPGATYDNCIRLNYSAEWSPSIESAVQTLGKVATHLLAKRSSGRGE

Sequences:

>Translated_479_residues
MKLYEKLAADIEALVKQGVLLPGERIPSVRQASQHHRMSITTVIRAYVLLESRGIIESRPQSGYFVRPRSGETAVELLPS
RPSAKPSAVDVSALVLSTLRSIRSDDAVPLGSPYPDAALFPWQRINQYANNIARRYAKWTMLDDLPPGSPELIRQISRRY
LENGYAVNPNELIVTIGATEAINLCLQAVAKPGDTIAVESPTFYAMLHAIERLGMRAIEVATDPVEGIDIDALARLIDEK
NVAACMVMPNFQNPLGFQMPDEKKRALVEMLTSKDIPVIENDVYGELYYGEAHPSSLKAFDTAGIVLHCSSFSKTLTNAY
RIGWALPGRYRGAVERLKFLNTLTTPAIPQLAIAEFLKNDGYDFHLRRVRKAYAQQASIMAATVRRFFPEGTTTSRPAGG
YVLWVQLPEGIDAMEMYHAALEHRITVAPGHMFAPGATYDNCIRLNYSAEWSPSIESAVQTLGKVATHLLAKRSSGRGE
>Mature_479_residues
MKLYEKLAADIEALVKQGVLLPGERIPSVRQASQHHRMSITTVIRAYVLLESRGIIESRPQSGYFVRPRSGETAVELLPS
RPSAKPSAVDVSALVLSTLRSIRSDDAVPLGSPYPDAALFPWQRINQYANNIARRYAKWTMLDDLPPGSPELIRQISRRY
LENGYAVNPNELIVTIGATEAINLCLQAVAKPGDTIAVESPTFYAMLHAIERLGMRAIEVATDPVEGIDIDALARLIDEK
NVAACMVMPNFQNPLGFQMPDEKKRALVEMLTSKDIPVIENDVYGELYYGEAHPSSLKAFDTAGIVLHCSSFSKTLTNAY
RIGWALPGRYRGAVERLKFLNTLTTPAIPQLAIAEFLKNDGYDFHLRRVRKAYAQQASIMAATVRRFFPEGTTTSRPAGG
YVLWVQLPEGIDAMEMYHAALEHRITVAPGHMFAPGATYDNCIRLNYSAEWSPSIESAVQTLGKVATHLLAKRSSGRGE

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=24.8407643312102, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=24.8407643312102, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4507369, Length=159, Percent_Identity=28.3018867924528, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1787710, Length=465, Percent_Identity=41.0752688172043, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1790797, Length=465, Percent_Identity=33.9784946236559, Blast_Score=302, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6321000, Length=313, Percent_Identity=21.7252396166134, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356535, Length=327, Percent_Identity=25.0764525993884, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52956; Mature: 52956

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYEKLAADIEALVKQGVLLPGERIPSVRQASQHHRMSITTVIRAYVLLESRGIIESRP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QSGYFVRPRSGETAVELLPSRPSAKPSAVDVSALVLSTLRSIRSDDAVPLGSPYPDAALF
CCCEEEECCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PWQRINQYANNIARRYAKWTMLDDLPPGSPELIRQISRRYLENGYAVNPNELIVTIGATE
CHHHHHHHHHHHHHHHHHHHECCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHH
AINLCLQAVAKPGDTIAVESPTFYAMLHAIERLGMRAIEVATDPVEGIDIDALARLIDEK
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCC
NVAACMVMPNFQNPLGFQMPDEKKRALVEMLTSKDIPVIENDVYGELYYGEAHPSSLKAF
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCHHHHH
DTAGIVLHCSSFSKTLTNAYRIGWALPGRYRGAVERLKFLNTLTTPAIPQLAIAEFLKND
CCCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
GYDFHLRRVRKAYAQQASIMAATVRRFFPEGTTTSRPAGGYVLWVQLPEGIDAMEMYHAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
LEHRITVAPGHMFAPGATYDNCIRLNYSAEWSPSIESAVQTLGKVATHLLAKRSSGRGE
HHCEEEECCCCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLYEKLAADIEALVKQGVLLPGERIPSVRQASQHHRMSITTVIRAYVLLESRGIIESRP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QSGYFVRPRSGETAVELLPSRPSAKPSAVDVSALVLSTLRSIRSDDAVPLGSPYPDAALF
CCCEEEECCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PWQRINQYANNIARRYAKWTMLDDLPPGSPELIRQISRRYLENGYAVNPNELIVTIGATE
CHHHHHHHHHHHHHHHHHHHECCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHH
AINLCLQAVAKPGDTIAVESPTFYAMLHAIERLGMRAIEVATDPVEGIDIDALARLIDEK
HHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCC
NVAACMVMPNFQNPLGFQMPDEKKRALVEMLTSKDIPVIENDVYGELYYGEAHPSSLKAF
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCCHHHHH
DTAGIVLHCSSFSKTLTNAYRIGWALPGRYRGAVERLKFLNTLTTPAIPQLAIAEFLKND
CCCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
GYDFHLRRVRKAYAQQASIMAATVRRFFPEGTTTSRPAGGYVLWVQLPEGIDAMEMYHAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
LEHRITVAPGHMFAPGATYDNCIRLNYSAEWSPSIESAVQTLGKVATHLLAKRSSGRGE
HHCEEEECCCCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]