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The map label for this gene is pgl [H]

Identifier: 73537919

GI number: 73537919

Start: 727369

End: 728064

Strand: Reverse

Name: pgl [H]

Synonym: Reut_B4086

Alternate gene names: 73537919

Gene position: 728064-727369 (Counterclockwise)

Preceding gene: 73537920

Following gene: 73537918

Centisome position: 26.71

GC content: 66.09

Gene sequence:

>696_bases
ATGCGCCAAATCGAACTGAACGATGCCTGCGCGCACGCCGATGCCATGGCGCGCGCCGTGGCGTGCGAGCTGGAACGCAC
GCTGGCCAGCAAGGAGGAAGCTTGCCTGGCCATCTCGGGGGACCGTTTGCCGCTGCCGCTGTTCGCGGCATTGCAACAGC
GCCCCTTGCCATGGGATCGCATCAGCGTCATGCTCGTTGACGAGCGCATGGTCCCCATCGATCACACAGACAGCAATGCA
CGGCTCGTCTGCGACGTGCTGTTGCGCCAGGCCGCTTCGCGCGCGACGTTCCAGCCGCCCGTGCCGACGTTCTGTACGGA
GATCGAAGAGATCGACACTTCGGCCGTCGTGGCCGAACTGAACCGCAATTACCGCCAGCCTGACGTGGTCGTGCTCGGCA
TGGGCGACGATGGCCATACCGCGTCGCTGTTTGCGGATGCGCCCGAACTGTCCGTAGGCCTGTCGCTGAACGAGCCCCCG
GGCTACCTCGCCATGAGCCCGCGCGCGGCACCGCACCGCCGCGTCAGCCTGAACCTGCGTGCGTTGCTGGGCGCGCGGCG
TGTGCTGCTGAGCTTCAGCGGGCCGTGGAAGAAACAGGTATTCGATGCCGCCACCATGGAGCCCACGCCGATGCTGCCGG
TCAGCTACCTGCTGCACCAGGACAGCACGCCCGTGGATGTCTACTGGACCCAATAG

Upstream 100 bases:

>100_bases
ACCGGAATACCGGCATGAGCATGCCGTCCGGCCGCACGCGAGCCAGGCGTTGCACCCCGCCGTGGATCGCCTTGCCGCCA
CCTGCAGGGAGGAAGAGCCA

Downstream 100 bases:

>100_bases
GCGTCTCGTTCTGGCACCCTGATTCCCGCAATGCAAATACAGGCCTTGTTGCGCCGTAGGACAACGCCTGACAACAATCG
GCACCGCCGCGCGCTACAGT

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRQIELNDACAHADAMARAVACELERTLASKEEACLAISGDRLPLPLFAALQQRPLPWDRISVMLVDERMVPIDHTDSNA
RLVCDVLLRQAASRATFQPPVPTFCTEIEEIDTSAVVAELNRNYRQPDVVVLGMGDDGHTASLFADAPELSVGLSLNEPP
GYLAMSPRAAPHRRVSLNLRALLGARRVLLSFSGPWKKQVFDAATMEPTPMLPVSYLLHQDSTPVDVYWTQ

Sequences:

>Translated_231_residues
MRQIELNDACAHADAMARAVACELERTLASKEEACLAISGDRLPLPLFAALQQRPLPWDRISVMLVDERMVPIDHTDSNA
RLVCDVLLRQAASRATFQPPVPTFCTEIEEIDTSAVVAELNRNYRQPDVVVLGMGDDGHTASLFADAPELSVGLSLNEPP
GYLAMSPRAAPHRRVSLNLRALLGARRVLLSFSGPWKKQVFDAATMEPTPMLPVSYLLHQDSTPVDVYWTQ
>Mature_231_residues
MRQIELNDACAHADAMARAVACELERTLASKEEACLAISGDRLPLPLFAALQQRPLPWDRISVMLVDERMVPIDHTDSNA
RLVCDVLLRQAASRATFQPPVPTFCTEIEEIDTSAVVAELNRNYRQPDVVVLGMGDDGHTASLFADAPELSVGLSLNEPP
GYLAMSPRAAPHRRVSLNLRALLGARRVLLSFSGPWKKQVFDAATMEPTPMLPVSYLLHQDSTPVDVYWTQ

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=178, Percent_Identity=35.3932584269663, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25472; Mature: 25472

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIELNDACAHADAMARAVACELERTLASKEEACLAISGDRLPLPLFAALQQRPLPWDR
CCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHH
ISVMLVDERMVPIDHTDSNARLVCDVLLRQAASRATFQPPVPTFCTEIEEIDTSAVVAEL
EEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHH
NRNYRQPDVVVLGMGDDGHTASLFADAPELSVGLSLNEPPGYLAMSPRAAPHRRVSLNLR
HCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEEEHHH
ALLGARRVLLSFSGPWKKQVFDAATMEPTPMLPVSYLLHQDSTPVDVYWTQ
HHHHHHHEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MRQIELNDACAHADAMARAVACELERTLASKEEACLAISGDRLPLPLFAALQQRPLPWDR
CCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHH
ISVMLVDERMVPIDHTDSNARLVCDVLLRQAASRATFQPPVPTFCTEIEEIDTSAVVAEL
EEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHH
NRNYRQPDVVVLGMGDDGHTASLFADAPELSVGLSLNEPPGYLAMSPRAAPHRRVSLNLR
HCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEEEHHH
ALLGARRVLLSFSGPWKKQVFDAATMEPTPMLPVSYLLHQDSTPVDVYWTQ
HHHHHHHEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]