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The map label for this gene is hexR [H]

Identifier: 73537854

GI number: 73537854

Start: 661336

End: 662256

Strand: Reverse

Name: hexR [H]

Synonym: Reut_B4021

Alternate gene names: 73537854

Gene position: 662256-661336 (Counterclockwise)

Preceding gene: 73537858

Following gene: 73537853

Centisome position: 24.29

GC content: 69.49

Gene sequence:

>921_bases
ATGACCGCGCCTTTCGATATCCTGACCCGCATCGCCGAGCGCGGCCCCGCGTTGCGCCTGGCCGAGCAGAAAGTGGCGCA
GGTGGTACTGGAAGACCTGGCCGGCGCAGCAGCAGCCAGCATCAATGAACTGGCGCGCAAGGCCGGCGTGAGCGAAGCGA
GCGTGACGCGCTTTGCCAAGGCCATCGGCTGCCGCGACGTGCGCGACCTCAAGCTGCGGTTAGCGCAAGCGACTGCGGTT
GGCATGCGCTTCCTTGACCCCGATGGCGTGCCGGCACCCGCCGATGCCCCCGCCACCGTGGCGGACCGCATCCATGCCGA
CGTGCTCACCGCGCTCGAGGTCAATCGCAAGCTCATCGACACCGACCGCATGGAACAGGCTGCGCGCCTGTTGCTCGGCG
CACGCATGGTCTACGCTTTTGGCATGGGCGGCGGCTCGTCGATCATGGCCGACGAAGCGCGCCACCGCCTGGCGCGTCTG
GGGCAACCCGTGGCCAGCTACCAGGACGGGCTGCTGCAGAAGATGGTGGCCGCGACGCTCAGCCGCGACGACGTGGTGCT
CGCGTTTTCGGCCAGCGGCAGCGTGCCGGAGATGCTGGCGAGCTGCGATATCGCGCGCGAATACGGCGCGAAGCTGGTGG
CCGTGACCGCGCTCGGTTCGCCGCTGGCTGCGCGTGCCGACGTGCTGCTGCCGGTGCGCACGCTCGAGACCGACTTCATT
TTCAAGCCGTCGGCCTCGCGCTACGCGATGCTGCTGGTGCTCGATGTCCTGGCCACGCAATGCGCGCTGCTGCAGCAGGA
CCAGAGCAAGGAACGGCTGCGCCGCCTGAAATATGTGCTCGACGCCCACCGCGGTCCCGCTGGTGAGCGCGGCCCGGACA
GCGGCGCCGGCCCGGACGGCCGCCAGCCGCTGGGAGACTGA

Upstream 100 bases:

>100_bases
GAGCGACAACCGGATGCGATCAGCGCCCCGCTGCGGCAACGCGACAGGGCCGGCATTACCAGTTATAGCCCTTCGCCAGC
CCACGGACCCTCCCTCAGCC

Downstream 100 bases:

>100_bases
CCTATGCCACACCTGTTTGATACCCTGATCCGCTGCGTCATGCTGATCGACGGCTCGGGCGCCGCGGCGCGCATGGCCGA
CGTGGCGCTGCGCGATGGCC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTAPFDILTRIAERGPALRLAEQKVAQVVLEDLAGAAAASINELARKAGVSEASVTRFAKAIGCRDVRDLKLRLAQATAV
GMRFLDPDGVPAPADAPATVADRIHADVLTALEVNRKLIDTDRMEQAARLLLGARMVYAFGMGGGSSIMADEARHRLARL
GQPVASYQDGLLQKMVAATLSRDDVVLAFSASGSVPEMLASCDIAREYGAKLVAVTALGSPLAARADVLLPVRTLETDFI
FKPSASRYAMLLVLDVLATQCALLQQDQSKERLRRLKYVLDAHRGPAGERGPDSGAGPDGRQPLGD

Sequences:

>Translated_306_residues
MTAPFDILTRIAERGPALRLAEQKVAQVVLEDLAGAAAASINELARKAGVSEASVTRFAKAIGCRDVRDLKLRLAQATAV
GMRFLDPDGVPAPADAPATVADRIHADVLTALEVNRKLIDTDRMEQAARLLLGARMVYAFGMGGGSSIMADEARHRLARL
GQPVASYQDGLLQKMVAATLSRDDVVLAFSASGSVPEMLASCDIAREYGAKLVAVTALGSPLAARADVLLPVRTLETDFI
FKPSASRYAMLLVLDVLATQCALLQQDQSKERLRRLKYVLDAHRGPAGERGPDSGAGPDGRQPLGD
>Mature_305_residues
TAPFDILTRIAERGPALRLAEQKVAQVVLEDLAGAAAASINELARKAGVSEASVTRFAKAIGCRDVRDLKLRLAQATAVG
MRFLDPDGVPAPADAPATVADRIHADVLTALEVNRKLIDTDRMEQAARLLLGARMVYAFGMGGGSSIMADEARHRLARLG
QPVASYQDGLLQKMVAATLSRDDVVLAFSASGSVPEMLASCDIAREYGAKLVAVTALGSPLAARADVLLPVRTLETDFIF
KPSASRYAMLLVLDVLATQCALLQQDQSKERLRRLKYVLDAHRGPAGERGPDSGAGPDGRQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=279, Percent_Identity=30.8243727598566, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082369, Length=261, Percent_Identity=25.6704980842912, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788767, Length=256, Percent_Identity=26.5625, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32510; Mature: 32379

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS51071 HTH_RPIR ; PS00579 RIBOSOMAL_L29

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPFDILTRIAERGPALRLAEQKVAQVVLEDLAGAAAASINELARKAGVSEASVTRFAK
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AIGCRDVRDLKLRLAQATAVGMRFLDPDGVPAPADAPATVADRIHADVLTALEVNRKLID
HHCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TDRMEQAARLLLGARMVYAFGMGGGSSIMADEARHRLARLGQPVASYQDGLLQKMVAATL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
SRDDVVLAFSASGSVPEMLASCDIAREYGAKLVAVTALGSPLAARADVLLPVRTLETDFI
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHCHHEEEHHHHCCCEE
FKPSASRYAMLLVLDVLATQCALLQQDQSKERLRRLKYVLDAHRGPAGERGPDSGAGPDG
ECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RQPLGD
CCCCCC
>Mature Secondary Structure 
TAPFDILTRIAERGPALRLAEQKVAQVVLEDLAGAAAASINELARKAGVSEASVTRFAK
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AIGCRDVRDLKLRLAQATAVGMRFLDPDGVPAPADAPATVADRIHADVLTALEVNRKLID
HHCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TDRMEQAARLLLGARMVYAFGMGGGSSIMADEARHRLARLGQPVASYQDGLLQKMVAATL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
SRDDVVLAFSASGSVPEMLASCDIAREYGAKLVAVTALGSPLAARADVLLPVRTLETDFI
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHCHHEEEHHHHCCCEE
FKPSASRYAMLLVLDVLATQCALLQQDQSKERLRRLKYVLDAHRGPAGERGPDSGAGPDG
ECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RQPLGD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]