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The map label for this gene is gbpR [H]

Identifier: 73537797

GI number: 73537797

Start: 597444

End: 598391

Strand: Reverse

Name: gbpR [H]

Synonym: Reut_B3964

Alternate gene names: 73537797

Gene position: 598391-597444 (Counterclockwise)

Preceding gene: 73537801

Following gene: 73537793

Centisome position: 21.95

GC content: 67.72

Gene sequence:

>948_bases
ATGTCCATTGCTTCCGACAAACTGGTCCATCGCGTCATATCGCGGCTGCGCCTGCGGCACATGCCGCTGCTGCTGGCGCT
GGAACAGCAGCGGTCGGTATCGCGCGTCGCCGCGGAAATGAACCTGTCGCAGCCCGCTGTCACCAAGATGCTGCGCGAAA
TCGAAGACATCTTCACGGTGCCGCTGTTCACGCGTACGCGGCAAGGGCTTGAGCCGACCCCAACCGGCCTGAGCGTGCTC
GCGCACGCGCGCCTGGCGCTGGCCGACGCGGACGCGCTTAGCCGCGAACTGGCCGTAATCGAGGCCGGGTTGTCCGGACG
CCTGCGCCTTGGCGTGATCCCGTACATCGCGCGGCCAGTGCTCGATGCCGCCTGCACGTTCGGGCTGGGGCGCTCGCCTC
GCATCTCGGTGCTGGTGCGCGAAGGCACCACGGATGAACTGGTGGCCGCGCTGCGTGCCCACGAACTCGACTGCGTAATC
GCGCGTACGTTTTACGTGCCCGGCGAAGACATCGCGCAACGGCCGCTCTACCGCGAAGAGCCGGTGCTGGTCGTGCCAAG
CAAGGTGGCGACGCGGCTGTCAGGCAGCGCCCTGGACTGGGGCCGGCTGGCCGAGCGCGACTGGATCCTGCCGCCGCCCA
ATACGCCGATCCGGCGCACCATCAACACCATGTTCGCGGTGGCCGGCGTGGCCCAGCCCACGCCAATCGTCGAAACGTAC
TCGATCAAGACCATGGCTACCGTGATGCGTAGCCATCTGGGTGCCATCACCATCGTGCCCAGAGGCGTTGCCGCCGAACT
GGTCGAAGCCGAGGGCGCGACGATGCTGCCGCATCCGCTGAGCTGGGACTTGCCGCCGGTGGGCGTGATGTGGCGAAGGG
AATCCGGCGAGGATGAGAAGATCGCGGCGCTCGTGGCCAGCGTGGCCGCGGTGGGGGGACGCGTCTAG

Upstream 100 bases:

>100_bases
GGTTCAAGCCAGTATAGGAGCATGAAATAACCGCAATGATGTCTTTGGTTATCATTGCATTACCGATTGGTTATACGACT
TCGCTGCGCCCCTACCCCCT

Downstream 100 bases:

>100_bases
TCTGCTCGCTTCTCCACTCTCCCTGAAGCGAGAGAGCGGAGCCGGCCATCAATGATCCGGCATCGGCAACGACTCAATGC
TCGCAATTCACCATCCAGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSIASDKLVHRVISRLRLRHMPLLLALEQQRSVSRVAAEMNLSQPAVTKMLREIEDIFTVPLFTRTRQGLEPTPTGLSVL
AHARLALADADALSRELAVIEAGLSGRLRLGVIPYIARPVLDAACTFGLGRSPRISVLVREGTTDELVAALRAHELDCVI
ARTFYVPGEDIAQRPLYREEPVLVVPSKVATRLSGSALDWGRLAERDWILPPPNTPIRRTINTMFAVAGVAQPTPIVETY
SIKTMATVMRSHLGAITIVPRGVAAELVEAEGATMLPHPLSWDLPPVGVMWRRESGEDEKIAALVASVAAVGGRV

Sequences:

>Translated_315_residues
MSIASDKLVHRVISRLRLRHMPLLLALEQQRSVSRVAAEMNLSQPAVTKMLREIEDIFTVPLFTRTRQGLEPTPTGLSVL
AHARLALADADALSRELAVIEAGLSGRLRLGVIPYIARPVLDAACTFGLGRSPRISVLVREGTTDELVAALRAHELDCVI
ARTFYVPGEDIAQRPLYREEPVLVVPSKVATRLSGSALDWGRLAERDWILPPPNTPIRRTINTMFAVAGVAQPTPIVETY
SIKTMATVMRSHLGAITIVPRGVAAELVEAEGATMLPHPLSWDLPPVGVMWRRESGEDEKIAALVASVAAVGGRV
>Mature_314_residues
SIASDKLVHRVISRLRLRHMPLLLALEQQRSVSRVAAEMNLSQPAVTKMLREIEDIFTVPLFTRTRQGLEPTPTGLSVLA
HARLALADADALSRELAVIEAGLSGRLRLGVIPYIARPVLDAACTFGLGRSPRISVLVREGTTDELVAALRAHELDCVIA
RTFYVPGEDIAQRPLYREEPVLVVPSKVATRLSGSALDWGRLAERDWILPPPNTPIRRTINTMFAVAGVAQPTPIVETYS
IKTMATVMRSHLGAITIVPRGVAAELVEAEGATMLPHPLSWDLPPVGVMWRRESGEDEKIAALVASVAAVGGRV

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=299, Percent_Identity=22.742474916388, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081904, Length=282, Percent_Identity=25.886524822695, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790399, Length=169, Percent_Identity=27.810650887574, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=284, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789506, Length=252, Percent_Identity=24.6031746031746, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788297, Length=262, Percent_Identity=24.0458015267176, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34252; Mature: 34121

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIASDKLVHRVISRLRLRHMPLLLALEQQRSVSRVAAEMNLSQPAVTKMLREIEDIFTV
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
PLFTRTRQGLEPTPTGLSVLAHARLALADADALSRELAVIEAGLSGRLRLGVIPYIARPV
CHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHH
LDAACTFGLGRSPRISVLVREGTTDELVAALRAHELDCVIARTFYVPGEDIAQRPLYREE
HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEEECCCHHHHHCCCCCCC
PVLVVPSKVATRLSGSALDWGRLAERDWILPPPNTPIRRTINTMFAVAGVAQPTPIVETY
CEEEECHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHH
SIKTMATVMRSHLGAITIVPRGVAAELVEAEGATMLPHPLSWDLPPVGVMWRRESGEDEK
HHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCEECCCCCCCCCCCCCEEEECCCCCHHH
IAALVASVAAVGGRV
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIASDKLVHRVISRLRLRHMPLLLALEQQRSVSRVAAEMNLSQPAVTKMLREIEDIFTV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
PLFTRTRQGLEPTPTGLSVLAHARLALADADALSRELAVIEAGLSGRLRLGVIPYIARPV
CHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHH
LDAACTFGLGRSPRISVLVREGTTDELVAALRAHELDCVIARTFYVPGEDIAQRPLYREE
HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEEECCCHHHHHCCCCCCC
PVLVVPSKVATRLSGSALDWGRLAERDWILPPPNTPIRRTINTMFAVAGVAQPTPIVETY
CEEEECHHHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHH
SIKTMATVMRSHLGAITIVPRGVAAELVEAEGATMLPHPLSWDLPPVGVMWRRESGEDEK
HHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCEECCCCCCCCCCCCCEEEECCCCCHHH
IAALVASVAAVGGRV
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]