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The map label for this gene is lig [H]

Identifier: 73537730

GI number: 73537730

Start: 524523

End: 525629

Strand: Reverse

Name: lig [H]

Synonym: Reut_B3896

Alternate gene names: 73537730

Gene position: 525629-524523 (Counterclockwise)

Preceding gene: 73537732

Following gene: 73537729

Centisome position: 19.28

GC content: 69.29

Gene sequence:

>1107_bases
TTGGACCACCCACGGCCGCCCACATCCGAATCCCGCCACGCCCACGACCTTATCATCGCCCGCCCCGAGGGCCTTTACTG
CCCGCCCGGTGACTTCTACATCGACCCGTGGCGCCCGGTAGATCGCGCCGTCATTACCCACGCTCATTCCGACCACGCCC
GTTTCGGCCACGCGCACTACCTGTGCGCTGAACCCGGTCGCGGCGTGCTGCTGGCACGGCTGCCTGGCATTCAGCTCGAC
ACCCTGCCGTACGGCCAGCGCATCACGCACCACGGCGTCACGCTGAGCCTGCATCCGGCCGGCCATGTGCTTGGCTCCGC
GCAGGTGCGACTCGAATTCGGCGGCCAGGTATGGGTGGCCTCCGGCGACTACAAGCTGGAATCCGATGGCACTTGCGACC
CGTTCGAGCCGGTGCCGTGCGACACCTTCATCACCGAAAGCACCTTCGGCCTGCCGATCTACCGCTGGCCGCCGCAGGCG
GCACTGATGGCGGAGGTTTTCCACTGGTGGCAGGCCAACGCGCAGGCAGGACGCGCCAGCATCGTTTACGCCTACACCTT
CGGCAAGGCACAGCGCATCCTGCACGGCCTGCTGCGCCATGCCGGCGATGACGGCCTGCCAGGGCCAGTCATCGCACACG
GCGCGCTGACCACGCTCAACGGCGCCTATGCCGAAGCCGGCGTGGCGCTGCCGCCGATGATGCTCGCCACCGAACTGCCG
CCACGCAGCCCGCTGCTGCGGCAGGCACTGGTGGTAGCGCCGCCGTCGGCGCAGCGCTCGCCTTGGCTGCGCCGCTTTGG
CGATGCGTCCGATGCGTTCGCCAGCGGCTGGATGCAGTTGCGCGGCACGCGCAGGCGCCGCGGCGTGGACCGCGGCTTCG
CGCTGTCCGATCATGCCGACTGGCCCGGGCTGCTGAAAGCGATCGAAGCGACCGGCGCCGGCCGCGTGATCGTGACGCAC
GGCAATGTGCCGGTGATGGTGCGCTACCTCAGCGAGCGCGGCTGGCAGGCGCAGGCGTTCGATACCGAATACGGCGACGA
CGACGAATCCGCACGCGCCGATGAGCAGGCTGAGCCAGCCGCCGCCAGTGAGGATACGGCGCCATGA

Upstream 100 bases:

>100_bases
GCGAATCGGCCGCAACCGGCTCCACAACCCGTAAGCGCACGAAGTATGATGCTCGCGTCTTCATGGCGGCTTGCGGGCCG
CAGTGCGTCAGGAGGCAAGC

Downstream 100 bases:

>100_bases
AGGCCTTTGCCGATCTCTACGCCGCGCTCGACGGCACCACCTCCACCAAGGCGCGGCTGGCCGCGCTGGTGGACTACCTG
CGCGCGGCGCCGCCGCAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MDHPRPPTSESRHAHDLIIARPEGLYCPPGDFYIDPWRPVDRAVITHAHSDHARFGHAHYLCAEPGRGVLLARLPGIQLD
TLPYGQRITHHGVTLSLHPAGHVLGSAQVRLEFGGQVWVASGDYKLESDGTCDPFEPVPCDTFITESTFGLPIYRWPPQA
ALMAEVFHWWQANAQAGRASIVYAYTFGKAQRILHGLLRHAGDDGLPGPVIAHGALTTLNGAYAEAGVALPPMMLATELP
PRSPLLRQALVVAPPSAQRSPWLRRFGDASDAFASGWMQLRGTRRRRGVDRGFALSDHADWPGLLKAIEATGAGRVIVTH
GNVPVMVRYLSERGWQAQAFDTEYGDDDESARADEQAEPAAASEDTAP

Sequences:

>Translated_368_residues
MDHPRPPTSESRHAHDLIIARPEGLYCPPGDFYIDPWRPVDRAVITHAHSDHARFGHAHYLCAEPGRGVLLARLPGIQLD
TLPYGQRITHHGVTLSLHPAGHVLGSAQVRLEFGGQVWVASGDYKLESDGTCDPFEPVPCDTFITESTFGLPIYRWPPQA
ALMAEVFHWWQANAQAGRASIVYAYTFGKAQRILHGLLRHAGDDGLPGPVIAHGALTTLNGAYAEAGVALPPMMLATELP
PRSPLLRQALVVAPPSAQRSPWLRRFGDASDAFASGWMQLRGTRRRRGVDRGFALSDHADWPGLLKAIEATGAGRVIVTH
GNVPVMVRYLSERGWQAQAFDTEYGDDDESARADEQAEPAAASEDTAP
>Mature_368_residues
MDHPRPPTSESRHAHDLIIARPEGLYCPPGDFYIDPWRPVDRAVITHAHSDHARFGHAHYLCAEPGRGVLLARLPGIQLD
TLPYGQRITHHGVTLSLHPAGHVLGSAQVRLEFGGQVWVASGDYKLESDGTCDPFEPVPCDTFITESTFGLPIYRWPPQA
ALMAEVFHWWQANAQAGRASIVYAYTFGKAQRILHGLLRHAGDDGLPGPVIAHGALTTLNGAYAEAGVALPPMMLATELP
PRSPLLRQALVVAPPSAQRSPWLRRFGDASDAFASGWMQLRGTRRRRGVDRGFALSDHADWPGLLKAIEATGAGRVIVTH
GNVPVMVRYLSERGWQAQAFDTEYGDDDESARADEQAEPAAASEDTAP

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 40122; Mature: 40122

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHPRPPTSESRHAHDLIIARPEGLYCPPGDFYIDPWRPVDRAVITHAHSDHARFGHAHY
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCCEEE
LCAEPGRGVLLARLPGIQLDTLPYGQRITHHGVTLSLHPAGHVLGSAQVRLEFGGQVWVA
EECCCCCCEEEEECCCCEEECCCCCCEEEECCEEEEECCCCCEECCEEEEEEECCEEEEE
SGDYKLESDGTCDPFEPVPCDTFITESTFGLPIYRWPPQAALMAEVFHWWQANAQAGRAS
CCCEEECCCCCCCCCCCCCCCCEECCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEE
IVYAYTFGKAQRILHGLLRHAGDDGLPGPVIAHGALTTLNGAYAEAGVALPPMMLATELP
EEEEEECCHHHHHHHHHHHHCCCCCCCCCEEECCHHHHCCCHHHHCCCCCCCHHHHHCCC
PRSPLLRQALVVAPPSAQRSPWLRRFGDASDAFASGWMQLRGTRRRRGVDRGFALSDHAD
CCCHHHHHEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCCCEECCCCC
WPGLLKAIEATGAGRVIVTHGNVPVMVRYLSERGWQAQAFDTEYGDDDESARADEQAEPA
CHHHHHHHHHCCCCEEEEEECCCCEEEEEHHHCCCEEEECCCCCCCCCCHHCCCCCCCCC
AASEDTAP
CCCCCCCC
>Mature Secondary Structure
MDHPRPPTSESRHAHDLIIARPEGLYCPPGDFYIDPWRPVDRAVITHAHSDHARFGHAHY
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCCCEEE
LCAEPGRGVLLARLPGIQLDTLPYGQRITHHGVTLSLHPAGHVLGSAQVRLEFGGQVWVA
EECCCCCCEEEEECCCCEEECCCCCCEEEECCEEEEECCCCCEECCEEEEEEECCEEEEE
SGDYKLESDGTCDPFEPVPCDTFITESTFGLPIYRWPPQAALMAEVFHWWQANAQAGRAS
CCCEEECCCCCCCCCCCCCCCCEECCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEE
IVYAYTFGKAQRILHGLLRHAGDDGLPGPVIAHGALTTLNGAYAEAGVALPPMMLATELP
EEEEEECCHHHHHHHHHHHHCCCCCCCCCEEECCHHHHCCCHHHHCCCCCCCHHHHHCCC
PRSPLLRQALVVAPPSAQRSPWLRRFGDASDAFASGWMQLRGTRRRRGVDRGFALSDHAD
CCCHHHHHEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCCCEECCCCC
WPGLLKAIEATGAGRVIVTHGNVPVMVRYLSERGWQAQAFDTEYGDDDESARADEQAEPA
CHHHHHHHHHCCCCEEEEEECCCCEEEEEHHHCCCEEEECCCCCCCCCCHHCCCCCCCCC
AASEDTAP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA