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The map label for this gene is kipR [H]

Identifier: 73537714

GI number: 73537714

Start: 501117

End: 501923

Strand: Direct

Name: kipR [H]

Synonym: Reut_B3880

Alternate gene names: 73537714

Gene position: 501117-501923 (Clockwise)

Preceding gene: 73537710

Following gene: 73537715

Centisome position: 18.38

GC content: 63.94

Gene sequence:

>807_bases
ATGACCTCGAATCCACTGCCCGGACTTGCCAGTTCCGACGAACTGGCGACAGATCGCCAGTTCGCCATCAACCTGGCCCG
CGGCCTCGATGTGCTCCGGGCGTTCACGCCGGCGCGGCCGGTGCTGGGCAACCAGGATATCGTGGCCCAGACCGGGCTGC
CGAAGGCAACCGTCTCGCGACTCACCTATACGCTCTCGCTGCTCGGTTTCCTGAGCCGCGTGCCCAATAGCCAGAAATAC
CGGCTCGGTGCCGGGGTGCTGTCGCTCGCCTATCCCATGCTCGCCGGCCTCACGATTCGGCAGATCGCACGGCCATATAT
GGAAGCCATCGCCCAGCAGACAGGTTGCACGGTCAACCTGGGCATGCGTGAGCGCCTGTCTGTGGTGTACGTCGATAGTT
GCCGCGTCGATACCGCCAACATCTATCAGCCCGACATAGGCAGCACGCGTCCGCTGCTCGGCAGCTCGATCGGACGAGCC
ATTCTGCTCGCATGCGACGCGAAGGAGCGCACCGCCGTGCTGAACCGGTTGAGCGTCGGCGACGCCGAGCGCTTCGCCGC
CGAGAAGGTGATGTGGATAGCCGACCAGAAGCACTTCGCCGCGCACGGCTACTGCATCAGCCACGGCGAGTGGCGTACAG
AGATTCATGCAATCGCGGCACCGATCCGGCAGGGTTTGCACAACGATCCGTTCGCGCTGAACTGCACGGTCTCCGCAATG
CGCAACACCGGCGGGTACCTGGAACGGGACGTAGCGCCGCGACTGGTCGCGTGTGTGAAACAGATCGAATTGGCGTGTGC
ACGATAG

Upstream 100 bases:

>100_bases
CGCGGACAATCCTGGTTTCGCACAGCGGAACCGGTTCGCCCTGATATTGACTTCAACCGTCTGCCAAATGAGCATCGCCC
CAATGTTGCAGGATCCCTCC

Downstream 100 bases:

>100_bases
CACGCCGTGCCCGCATCGCAGACCGGCGCGGGCAGTGATTTTCAAAGCGGCCCGCAGCGGTTCGCATTCCAAAACAGGAG
ACTCGCATGGCACGACATGG

Product: regulatory protein IclR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTSNPLPGLASSDELATDRQFAINLARGLDVLRAFTPARPVLGNQDIVAQTGLPKATVSRLTYTLSLLGFLSRVPNSQKY
RLGAGVLSLAYPMLAGLTIRQIARPYMEAIAQQTGCTVNLGMRERLSVVYVDSCRVDTANIYQPDIGSTRPLLGSSIGRA
ILLACDAKERTAVLNRLSVGDAERFAAEKVMWIADQKHFAAHGYCISHGEWRTEIHAIAAPIRQGLHNDPFALNCTVSAM
RNTGGYLERDVAPRLVACVKQIELACAR

Sequences:

>Translated_268_residues
MTSNPLPGLASSDELATDRQFAINLARGLDVLRAFTPARPVLGNQDIVAQTGLPKATVSRLTYTLSLLGFLSRVPNSQKY
RLGAGVLSLAYPMLAGLTIRQIARPYMEAIAQQTGCTVNLGMRERLSVVYVDSCRVDTANIYQPDIGSTRPLLGSSIGRA
ILLACDAKERTAVLNRLSVGDAERFAAEKVMWIADQKHFAAHGYCISHGEWRTEIHAIAAPIRQGLHNDPFALNCTVSAM
RNTGGYLERDVAPRLVACVKQIELACAR
>Mature_267_residues
TSNPLPGLASSDELATDRQFAINLARGLDVLRAFTPARPVLGNQDIVAQTGLPKATVSRLTYTLSLLGFLSRVPNSQKYR
LGAGVLSLAYPMLAGLTIRQIARPYMEAIAQQTGCTVNLGMRERLSVVYVDSCRVDTANIYQPDIGSTRPLLGSSIGRAI
LLACDAKERTAVLNRLSVGDAERFAAEKVMWIADQKHFAAHGYCISHGEWRTEIHAIAAPIRQGLHNDPFALNCTVSAMR
NTGGYLERDVAPRLVACVKQIELACAR

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=152, Percent_Identity=28.2894736842105, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29122; Mature: 28991

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNPLPGLASSDELATDRQFAINLARGLDVLRAFTPARPVLGNQDIVAQTGLPKATVSR
CCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHH
LTYTLSLLGFLSRVPNSQKYRLGAGVLSLAYPMLAGLTIRQIARPYMEAIAQQTGCTVNL
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEC
GMRERLSVVYVDSCRVDTANIYQPDIGSTRPLLGSSIGRAILLACDAKERTAVLNRLSVG
CHHHCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHHHHHCCC
DAERFAAEKVMWIADQKHFAAHGYCISHGEWRTEIHAIAAPIRQGLHNDPFALNCTVSAM
CHHHHHHHHHHHEECCCHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
RNTGGYLERDVAPRLVACVKQIELACAR
HCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSNPLPGLASSDELATDRQFAINLARGLDVLRAFTPARPVLGNQDIVAQTGLPKATVSR
CCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHH
LTYTLSLLGFLSRVPNSQKYRLGAGVLSLAYPMLAGLTIRQIARPYMEAIAQQTGCTVNL
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEC
GMRERLSVVYVDSCRVDTANIYQPDIGSTRPLLGSSIGRAILLACDAKERTAVLNRLSVG
CHHHCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHHHHHCCC
DAERFAAEKVMWIADQKHFAAHGYCISHGEWRTEIHAIAAPIRQGLHNDPFALNCTVSAM
CHHHHHHHHHHHEECCCHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
RNTGGYLERDVAPRLVACVKQIELACAR
HCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]