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The map label for this gene is yfdE [H]

Identifier: 73537709

GI number: 73537709

Start: 494581

End: 495831

Strand: Direct

Name: yfdE [H]

Synonym: Reut_B3874

Alternate gene names: 73537709

Gene position: 494581-495831 (Clockwise)

Preceding gene: 73537708

Following gene: 73537710

Centisome position: 18.14

GC content: 66.43

Gene sequence:

>1251_bases
ATGCAAACAACAACCGAACCATCCCAGGACGTCGACTTCCCGCTGGAGGGCGTGCGTGTGCTGGACCTGTCGCGTGTGTT
CGCGGGGCCGCTGTGCGGCCAGGTCCTGGCCGACTTCGGCGCCGACGTGGTCAAGGTGGAACACCCCGGCCGCGGCGACG
ACACCCGTGACTGGGGCATGCGCATCGGCAAGACCGAGACCACGTACTTCAACAGCATGAACCGCAACAAGCGGTCCATC
ACGCTCGACCTGCAGAGCAAGGAAGGCGTGCAGATCGTCTATGACCTGCTGCCGCAGTTCGACGTGGTCATCCACAACTT
CAAGACCGGCGGCGCCGAAAAGCTGGGCCTCGGCTACGAGCAGCTCAAGGCCATCAAGCCGGACCTGATCTACTGCGCGG
TGTCGGGCTACAACACCAGCGGGCCCGAGGCCAAGCGGCCTGGCTACGACCTGGTGATCCAGGGCGAGGCTGGTCTGATG
GCGCTCAACGGCGAAGCGAACACGCCGCCGCTGAAGTTCGGCGTGGCCGTGGTCGACCTGATGACCGGCATGTATGCCGC
GCAGGCCGTGCTGGCCGCGCTGTTCCGCCGCGAGCGTAAGGGCAAGGGCCAGTTGATCGAGATGGCGCTGTACGACTGCG
GCGTGATGGTCACCGGCTACTACGGCCTGGACGCCATGCTGCTCGGCCATGATCCGGCACGCTACGGCAACGCCCACCCG
TCGATCGTGCCTTACGGCATGTTTGAGTCCGCCGATGGTCCGCTGATCATCGCCGTGGGCAACAACAGCCAGTTCGACAA
GTTTTGCCGCCAGGTCATCGAGCGTCCGGACATTGTCGAGAATCCGCTCTATGCGACCAATGTGGAACGCGCGAAGCACC
GCGAGACGCTGACCCCGCTGATCACCGGCCTGATCCGCAGCTTCAAGCGCGACCTGCTGCTGGAACGCATGACGGCCTGC
GGCATTCCGTGTGGCAAGGTGGCCGGCCTGCATGAGGCGCTGACCAGCGAGCGGACCCGCCAGGGCGGCCTGCTGCGCGA
AATGCCGCATCCGGTGGCAGGCAGCACGCACGTGTTCGCGCCGCCGTACCGCCTGGATGGCCAGCGCCTGCCGATCCGCA
GCGCGCCGCCGACGCTGGGCGAAGGCACGCGGGCCGTGCTGCAGAACCTGCTGGAGATGAGCGACGAGCAACTGCAGGAC
CTGCAGGCGCGCGGCGTACTGACGCTGCCGGAGACACCGGGCAACGCCTGA

Upstream 100 bases:

>100_bases
CTGACATGCCGGCGTCGCGCAGTGCGCGACGCCAGTGTGGCCAGAACAATTCATTGCAGCGAGGCGGCACATGCCTCGCT
GCAGCGCATGGAGACAAGCA

Downstream 100 bases:

>100_bases
GCATTCGCGCCGCGCGAACGCCATGAGTGTGCGCGCGGCCAGGCCCGGCAAGGGGGCCCCATGGAGACCTTGCACTGACT
CAAACCGGAACTAAAAGTGC

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MQTTTEPSQDVDFPLEGVRVLDLSRVFAGPLCGQVLADFGADVVKVEHPGRGDDTRDWGMRIGKTETTYFNSMNRNKRSI
TLDLQSKEGVQIVYDLLPQFDVVIHNFKTGGAEKLGLGYEQLKAIKPDLIYCAVSGYNTSGPEAKRPGYDLVIQGEAGLM
ALNGEANTPPLKFGVAVVDLMTGMYAAQAVLAALFRRERKGKGQLIEMALYDCGVMVTGYYGLDAMLLGHDPARYGNAHP
SIVPYGMFESADGPLIIAVGNNSQFDKFCRQVIERPDIVENPLYATNVERAKHRETLTPLITGLIRSFKRDLLLERMTAC
GIPCGKVAGLHEALTSERTRQGGLLREMPHPVAGSTHVFAPPYRLDGQRLPIRSAPPTLGEGTRAVLQNLLEMSDEQLQD
LQARGVLTLPETPGNA

Sequences:

>Translated_416_residues
MQTTTEPSQDVDFPLEGVRVLDLSRVFAGPLCGQVLADFGADVVKVEHPGRGDDTRDWGMRIGKTETTYFNSMNRNKRSI
TLDLQSKEGVQIVYDLLPQFDVVIHNFKTGGAEKLGLGYEQLKAIKPDLIYCAVSGYNTSGPEAKRPGYDLVIQGEAGLM
ALNGEANTPPLKFGVAVVDLMTGMYAAQAVLAALFRRERKGKGQLIEMALYDCGVMVTGYYGLDAMLLGHDPARYGNAHP
SIVPYGMFESADGPLIIAVGNNSQFDKFCRQVIERPDIVENPLYATNVERAKHRETLTPLITGLIRSFKRDLLLERMTAC
GIPCGKVAGLHEALTSERTRQGGLLREMPHPVAGSTHVFAPPYRLDGQRLPIRSAPPTLGEGTRAVLQNLLEMSDEQLQD
LQARGVLTLPETPGNA
>Mature_416_residues
MQTTTEPSQDVDFPLEGVRVLDLSRVFAGPLCGQVLADFGADVVKVEHPGRGDDTRDWGMRIGKTETTYFNSMNRNKRSI
TLDLQSKEGVQIVYDLLPQFDVVIHNFKTGGAEKLGLGYEQLKAIKPDLIYCAVSGYNTSGPEAKRPGYDLVIQGEAGLM
ALNGEANTPPLKFGVAVVDLMTGMYAAQAVLAALFRRERKGKGQLIEMALYDCGVMVTGYYGLDAMLLGHDPARYGNAHP
SIVPYGMFESADGPLIIAVGNNSQFDKFCRQVIERPDIVENPLYATNVERAKHRETLTPLITGLIRSFKRDLLLERMTAC
GIPCGKVAGLHEALTSERTRQGGLLREMPHPVAGSTHVFAPPYRLDGQRLPIRSAPPTLGEGTRAVLQNLLEMSDEQLQD
LQARGVLTLPETPGNA

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=411, Percent_Identity=36.0097323600973, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI300863124, Length=437, Percent_Identity=34.324942791762, Blast_Score=278, Evalue=5e-75,
Organism=Homo sapiens, GI13376042, Length=437, Percent_Identity=31.5789473684211, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI300863126, Length=412, Percent_Identity=32.5242718446602, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI266456254, Length=401, Percent_Identity=25.6857855361596, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI42794625, Length=401, Percent_Identity=25.6857855361596, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI266458393, Length=257, Percent_Identity=30.3501945525292, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI266458397, Length=253, Percent_Identity=30.4347826086957, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI42822893, Length=161, Percent_Identity=35.4037267080745, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI266458395, Length=154, Percent_Identity=35.7142857142857, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI87082093, Length=354, Percent_Identity=31.9209039548023, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1788717, Length=405, Percent_Identity=30.1234567901235, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786222, Length=413, Percent_Identity=23.728813559322, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32564160, Length=199, Percent_Identity=28.643216080402, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115535051, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648431, Length=403, Percent_Identity=38.9578163771712, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24585488, Length=410, Percent_Identity=26.0975609756098, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 45457; Mature: 45457

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTTEPSQDVDFPLEGVRVLDLSRVFAGPLCGQVLADFGADVVKVEHPGRGDDTRDWGM
CCCCCCCCCCCCCCCCCEEEEEHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCHHHCC
RIGKTETTYFNSMNRNKRSITLDLQSKEGVQIVYDLLPQFDVVIHNFKTGGAEKLGLGYE
CCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHCCCHH
QLKAIKPDLIYCAVSGYNTSGPEAKRPGYDLVIQGEAGLMALNGEANTPPLKFGVAVVDL
HHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
MTGMYAAQAVLAALFRRERKGKGQLIEMALYDCGVMVTGYYGLDAMLLGHDPARYGNAHP
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCEEEEEECCCEEEEECCCCHHCCCCCC
SIVPYGMFESADGPLIIAVGNNSQFDKFCRQVIERPDIVENPLYATNVERAKHRETLTPL
CEEECCCEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
ITGLIRSFKRDLLLERMTACGIPCGKVAGLHEALTSERTRQGGLLREMPHPVAGSTHVFA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEC
PPYRLDGQRLPIRSAPPTLGEGTRAVLQNLLEMSDEQLQDLQARGVLTLPETPGNA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCEEECCCCCCCC
>Mature Secondary Structure
MQTTTEPSQDVDFPLEGVRVLDLSRVFAGPLCGQVLADFGADVVKVEHPGRGDDTRDWGM
CCCCCCCCCCCCCCCCCEEEEEHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCHHHCC
RIGKTETTYFNSMNRNKRSITLDLQSKEGVQIVYDLLPQFDVVIHNFKTGGAEKLGLGYE
CCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHCCCHH
QLKAIKPDLIYCAVSGYNTSGPEAKRPGYDLVIQGEAGLMALNGEANTPPLKFGVAVVDL
HHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
MTGMYAAQAVLAALFRRERKGKGQLIEMALYDCGVMVTGYYGLDAMLLGHDPARYGNAHP
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCEEEEEECCCEEEEECCCCHHCCCCCC
SIVPYGMFESADGPLIIAVGNNSQFDKFCRQVIERPDIVENPLYATNVERAKHRETLTPL
CEEECCCEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
ITGLIRSFKRDLLLERMTACGIPCGKVAGLHEALTSERTRQGGLLREMPHPVAGSTHVFA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEC
PPYRLDGQRLPIRSAPPTLGEGTRAVLQNLLEMSDEQLQDLQARGVLTLPETPGNA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]