BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is fabG [H]

Identifier: 73537674

GI number: 73537674

Start: 452305

End: 453063

Strand: Reverse

Name: fabG [H]

Synonym: Reut_B3839

Alternate gene names: 73537674

Gene position: 453063-452305 (Counterclockwise)

Preceding gene: 73537675

Following gene: 73537666

Centisome position: 16.62

GC content: 65.35

Gene sequence:

>759_bases
ATGGACCTGAAGTTGAAAGGCAAGCGTGCAATCGTGACCGGCGGCAGCCGCGGCATTGGCAAGACGATTGCGCTGCAACT
CGCACAGGAAGGCGTGGATGTCGTGCTCGCCGCGCGCGGGAAAGACGCGCTGGAAGCGACCGCAGCGGAACTTGCGACGC
TGACCGGCCGCCGGATTGTGCCGCTCACGGTCGACACTGCCGACAAGGCTTCTGTCGACGCCATGGTGGAGCAAGCGATC
GAAGCGCTGGGCGGCATCGACATCCTGGTCAACGCCGCGGCGCTGCCGGGCGGCATCTCGCCGGCCACGCAACTGGATCA
GATCGTCGATGCGCAGGCACTCGAAGATATCGATATCAAGGTCATCGGCTATCTGCGCACCGCTCGGGCGCTGGCACCAC
ATCTGGCCAGCAATGGCTGGGGCCGCATCATCAATATCGGTGGCCTGGCGATCTACCATACGGGCCGGCCCGTCGCCACG
CTGCGCAATGTCGGCGTGGCGGCCATCACCAAGAACCTCGCTGATGAACTCGGCCCGAAGGGCATCAATGTCACGGTGGT
CCATCCCGGACCGACACGCACCGAGAAGACCGATGCGGCAACCGAGGCGTGGGCGGCGACGAAGAGCAGCCTCGGCCGCA
TGGTCGATGCCAGCGAGGTTGCCTGCGTGGTGACTTTCCTCGCTTCACCGCTGAGCGTGGCCATCAACGGCGAGGCCATC
CCGGTCGGCGGCGGAACCCCGGGCATCATCCACTACTGA

Upstream 100 bases:

>100_bases
CGCGGGCACCGCCGCCAGTGCGCCAGCCGCATCACGATCAACGGGGCGACGTGTTTATGGCACGATCGCCCCAAAGCCAT
TGCTGGATATCGGAGAAATC

Downstream 100 bases:

>100_bases
ACGTGCCCTGAACTGCTGACAGCTGCCTTGCCGCGCTGGCCCGCTTCAGAAGGGGCCAGGCCGGCGAGGCTGCCAGTTGC
GCTGTACTCAGTGAGCCTGA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MDLKLKGKRAIVTGGSRGIGKTIALQLAQEGVDVVLAARGKDALEATAAELATLTGRRIVPLTVDTADKASVDAMVEQAI
EALGGIDILVNAAALPGGISPATQLDQIVDAQALEDIDIKVIGYLRTARALAPHLASNGWGRIINIGGLAIYHTGRPVAT
LRNVGVAAITKNLADELGPKGINVTVVHPGPTRTEKTDAATEAWAATKSSLGRMVDASEVACVVTFLASPLSVAINGEAI
PVGGGTPGIIHY

Sequences:

>Translated_252_residues
MDLKLKGKRAIVTGGSRGIGKTIALQLAQEGVDVVLAARGKDALEATAAELATLTGRRIVPLTVDTADKASVDAMVEQAI
EALGGIDILVNAAALPGGISPATQLDQIVDAQALEDIDIKVIGYLRTARALAPHLASNGWGRIINIGGLAIYHTGRPVAT
LRNVGVAAITKNLADELGPKGINVTVVHPGPTRTEKTDAATEAWAATKSSLGRMVDASEVACVVTFLASPLSVAINGEAI
PVGGGTPGIIHY
>Mature_252_residues
MDLKLKGKRAIVTGGSRGIGKTIALQLAQEGVDVVLAARGKDALEATAAELATLTGRRIVPLTVDTADKASVDAMVEQAI
EALGGIDILVNAAALPGGISPATQLDQIVDAQALEDIDIKVIGYLRTARALAPHLASNGWGRIINIGGLAIYHTGRPVAT
LRNVGVAAITKNLADELGPKGINVTVVHPGPTRTEKTDAATEAWAATKSSLGRMVDASEVACVVTFLASPLSVAINGEAI
PVGGGTPGIIHY

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=32.9501915708812, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=30.0380228136882, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=32.2834645669291, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=30.9803921568627, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=29.1497975708502, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI4557649, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI40254986, Length=149, Percent_Identity=35.5704697986577, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI209862901, Length=264, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI19923983, Length=264, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4503301, Length=260, Percent_Identity=28.0769230769231, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI166795268, Length=210, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=31.8548387096774, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=32.9365079365079, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=29.6875, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=30.7392996108949, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=27.5193798449612, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=27.34375, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=28.0155642023346, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787545, Length=257, Percent_Identity=28.0155642023346, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=30.5882352941176, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=32.3076923076923, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71982365, Length=197, Percent_Identity=31.4720812182741, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=30.7984790874525, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=31.4393939393939, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=26.615969581749, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=30.1115241635688, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=276, Percent_Identity=27.8985507246377, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=25.6, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=27.037037037037, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=26.8774703557312, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=27.3408239700375, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=27.8810408921933, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=201, Percent_Identity=28.3582089552239, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=31.9230769230769, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=28.5171102661597, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=27.3408239700375, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=26.0223048327138, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=25.5102040816327, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=30.1204819277108, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=32.3076923076923, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=33.0739299610895, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=28.2352941176471, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=28.5140562248996, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=29.9212598425197, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=25.7936507936508, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25756; Mature: 25756

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKLKGKRAIVTGGSRGIGKTIALQLAQEGVDVVLAARGKDALEATAAELATLTGRRIV
CCCEECCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEE
PLTVDTADKASVDAMVEQAIEALGGIDILVNAAALPGGISPATQLDQIVDAQALEDIDIK
EEEECCCCHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHCCCCEE
VIGYLRTARALAPHLASNGWGRIINIGGLAIYHTGRPVATLRNVGVAAITKNLADELGPK
EEHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCHHHHHHCCHHHHHHHHHHHHCCC
GINVTVVHPGPTRTEKTDAATEAWAATKSSLGRMVDASEVACVVTFLASPLSVAINGEAI
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCEE
PVGGGTPGIIHY
ECCCCCCCCCCC
>Mature Secondary Structure
MDLKLKGKRAIVTGGSRGIGKTIALQLAQEGVDVVLAARGKDALEATAAELATLTGRRIV
CCCEECCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEE
PLTVDTADKASVDAMVEQAIEALGGIDILVNAAALPGGISPATQLDQIVDAQALEDIDIK
EEEECCCCHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCHHHHHHHHHHHHHCCCCEE
VIGYLRTARALAPHLASNGWGRIINIGGLAIYHTGRPVATLRNVGVAAITKNLADELGPK
EEHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCHHHHHHCCHHHHHHHHHHHHCCC
GINVTVVHPGPTRTEKTDAATEAWAATKSSLGRMVDASEVACVVTFLASPLSVAINGEAI
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCEE
PVGGGTPGIIHY
ECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]