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The map label for this gene is czcC [H]

Identifier: 73537637

GI number: 73537637

Start: 404035

End: 405432

Strand: Direct

Name: czcC [H]

Synonym: Reut_B3802

Alternate gene names: 73537637

Gene position: 404035-405432 (Clockwise)

Preceding gene: 73537636

Following gene: 73537638

Centisome position: 14.82

GC content: 68.1

Gene sequence:

>1398_bases
ATGGCGCAGGCAGCCTATGGCTTGCTTTCCCGACTCATGACACACACCAAGCTGACCCTGATCGCGTCGCTTTCGCTGGT
GGCGTTCGCGGCCGTGCCGGCCCAGGCCAGCGACGACATGCGCCCGCCGGCCGCCGTCGTCCTGGCTGGCGGCAACGTTG
CACCGCCCGCATCCGCTGCCCCAGTGACCGGTCCTTCCTATGGCCTGCAGCAACTGCTGGCGCTCGCGCAATCCACCAAC
AAGGGCGTCGAGGCCGCGCAGGCCAATGTCGATGCCGCCAATGCCGCCATCACTAGCGCGCGCGCCTATCCGAACCCGCA
GGTCGAGGTGATGTACGGCCGCCTGCAGGGCAAGCAGCCGGGCGTGACCAGCGGCAACGCGCCCACCTACGCCATCACCC
AGAAGCTCGACTATCCGCACCAGCGCAGCCTGCGCCAGGACATGGCTTCGCGCAGCCTGGAAGCGTCTCAGGCCGTGCGC
CAGGGCTTTCGCGCCGAATTGGCCGCGCGCGTGAAGACGGCGTATTTCGAGGTTCTGCGCCGCGAGAGCGAACTCCAGGC
CGCGTCCGAAGACCTGGCGATGATGCGGCAGATCCATTCGCGCGCGCGCCTTCGCGTGGAAGTGGGCGAGGCCCCGCGCT
ATGAACTGATCAAGGCAGAGACCGAATTGCTCGCGACGCAGAAAAGCGCGCAGACGGCGGAACTGCGCGTGAACCAGGCC
AAGGCCGCGCTGCGCCAGCAGGTTGGCGGCGCCATGCCGGCGCTGTTCTCGCTGGACGGCAATCTCGGCCAAGTGCCCGA
TGTGCCGCCGCTGCCGCAGTTGCGCGGCACGATGAACGCCAGCAACGCCGAACTGACCCAGCGCCGCATGGAACTCGAGC
GCGCGCGCCTCGGCGTGGATTACCAGCGTTCGCTGCGCTGGCCCGAAGTCGCCGTGCGCGCGAGCACGGACCGCCAGCCG
GACAACAACGTCTCGCAGATCGGGCTGGTGGTGACGATTCCGCTGTGGGACCGCCGCAGCGGTCCGGTGGGCGAAGCCAC
CGCGCAGGCCACGCAGGCGCGCACTGCGCTGGAAGCGCGCGAATTCGAGCTGACGCAGGAACTGGAAGCCGCGTACCGCC
AGTACGAAATCACACAGTCGCAGGTGACAGCACTGGAGTCCGGCATCGTGCGCGAAGCCGAGTCCGCGCTGAACGTGGCC
GAGTCCGCCTACCGCTTCGGCGAGCGCGGCATTCTCGATTACCTGGACGCGCAGCGCGTGCTGCGCGGCGCGCGCAATGA
ACTGATCGCGGCGCAGTTCGACCTGCAGGTCGCTGCCATCCAGATCGAAAAGCTCATGTCGACGGCCCTGGGCACCGCGC
CTGCTGCGCTGCCGTCTTCCACCATCCAGAACCGATAA

Upstream 100 bases:

>100_bases
GCCCAGAACTCCCGGCGCGCCTTAACGGTAGCCGGCTGAGTCCGTTGCGGTACGTCTGCCGTCCGTCTCGCGCATCGCGC
GAGGGGGCGGGCGATGACGC

Downstream 100 bases:

>100_bases
TCATGCGCCCCAATTTCCTGCTTTCGCTGACGGCCACTGCCGTCATGGTGTTTGCCCTGGCAGGCTGCTCGAAGGAGCCG
GCCCAAGCGACCGAAGCCCC

Product: Outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MAQAAYGLLSRLMTHTKLTLIASLSLVAFAAVPAQASDDMRPPAAVVLAGGNVAPPASAAPVTGPSYGLQQLLALAQSTN
KGVEAAQANVDAANAAITSARAYPNPQVEVMYGRLQGKQPGVTSGNAPTYAITQKLDYPHQRSLRQDMASRSLEASQAVR
QGFRAELAARVKTAYFEVLRRESELQAASEDLAMMRQIHSRARLRVEVGEAPRYELIKAETELLATQKSAQTAELRVNQA
KAALRQQVGGAMPALFSLDGNLGQVPDVPPLPQLRGTMNASNAELTQRRMELERARLGVDYQRSLRWPEVAVRASTDRQP
DNNVSQIGLVVTIPLWDRRSGPVGEATAQATQARTALEAREFELTQELEAAYRQYEITQSQVTALESGIVREAESALNVA
ESAYRFGERGILDYLDAQRVLRGARNELIAAQFDLQVAAIQIEKLMSTALGTAPAALPSSTIQNR

Sequences:

>Translated_465_residues
MAQAAYGLLSRLMTHTKLTLIASLSLVAFAAVPAQASDDMRPPAAVVLAGGNVAPPASAAPVTGPSYGLQQLLALAQSTN
KGVEAAQANVDAANAAITSARAYPNPQVEVMYGRLQGKQPGVTSGNAPTYAITQKLDYPHQRSLRQDMASRSLEASQAVR
QGFRAELAARVKTAYFEVLRRESELQAASEDLAMMRQIHSRARLRVEVGEAPRYELIKAETELLATQKSAQTAELRVNQA
KAALRQQVGGAMPALFSLDGNLGQVPDVPPLPQLRGTMNASNAELTQRRMELERARLGVDYQRSLRWPEVAVRASTDRQP
DNNVSQIGLVVTIPLWDRRSGPVGEATAQATQARTALEAREFELTQELEAAYRQYEITQSQVTALESGIVREAESALNVA
ESAYRFGERGILDYLDAQRVLRGARNELIAAQFDLQVAAIQIEKLMSTALGTAPAALPSSTIQNR
>Mature_464_residues
AQAAYGLLSRLMTHTKLTLIASLSLVAFAAVPAQASDDMRPPAAVVLAGGNVAPPASAAPVTGPSYGLQQLLALAQSTNK
GVEAAQANVDAANAAITSARAYPNPQVEVMYGRLQGKQPGVTSGNAPTYAITQKLDYPHQRSLRQDMASRSLEASQAVRQ
GFRAELAARVKTAYFEVLRRESELQAASEDLAMMRQIHSRARLRVEVGEAPRYELIKAETELLATQKSAQTAELRVNQAK
AALRQQVGGAMPALFSLDGNLGQVPDVPPLPQLRGTMNASNAELTQRRMELERARLGVDYQRSLRWPEVAVRASTDRQPD
NNVSQIGLVVTIPLWDRRSGPVGEATAQATQARTALEAREFELTQELEAAYRQYEITQSQVTALESGIVREAESALNVAE
SAYRFGERGILDYLDAQRVLRGARNELIAAQFDLQVAAIQIEKLMSTALGTAPAALPSSTIQNR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=313, Percent_Identity=26.517571884984, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50251; Mature: 50119

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAAYGLLSRLMTHTKLTLIASLSLVAFAAVPAQASDDMRPPAAVVLAGGNVAPPASAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCC
PVTGPSYGLQQLLALAQSTNKGVEAAQANVDAANAAITSARAYPNPQVEVMYGRLQGKQP
CCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCC
GVTSGNAPTYAITQKLDYPHQRSLRQDMASRSLEASQAVRQGFRAELAARVKTAYFEVLR
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RESELQAASEDLAMMRQIHSRARLRVEVGEAPRYELIKAETELLATQKSAQTAELRVNQA
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAALRQQVGGAMPALFSLDGNLGQVPDVPPLPQLRGTMNASNAELTQRRMELERARLGVD
HHHHHHHHCCCCCCCEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
YQRSLRWPEVAVRASTDRQPDNNVSQIGLVVTIPLWDRRSGPVGEATAQATQARTALEAR
HHHHCCCCHHEEECCCCCCCCCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EFELTQELEAAYRQYEITQSQVTALESGIVREAESALNVAESAYRFGERGILDYLDAQRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRGARNELIAAQFDLQVAAIQIEKLMSTALGTAPAALPSSTIQNR
HHHHHHHHEEHHHCHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AQAAYGLLSRLMTHTKLTLIASLSLVAFAAVPAQASDDMRPPAAVVLAGGNVAPPASAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCC
PVTGPSYGLQQLLALAQSTNKGVEAAQANVDAANAAITSARAYPNPQVEVMYGRLQGKQP
CCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCC
GVTSGNAPTYAITQKLDYPHQRSLRQDMASRSLEASQAVRQGFRAELAARVKTAYFEVLR
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RESELQAASEDLAMMRQIHSRARLRVEVGEAPRYELIKAETELLATQKSAQTAELRVNQA
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAALRQQVGGAMPALFSLDGNLGQVPDVPPLPQLRGTMNASNAELTQRRMELERARLGVD
HHHHHHHHCCCCCCCEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
YQRSLRWPEVAVRASTDRQPDNNVSQIGLVVTIPLWDRRSGPVGEATAQATQARTALEAR
HHHHCCCCHHEEECCCCCCCCCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EFELTQELEAAYRQYEITQSQVTALESGIVREAESALNVAESAYRFGERGILDYLDAQRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LRGARNELIAAQFDLQVAAIQIEKLMSTALGTAPAALPSSTIQNR
HHHHHHHHEEHHHCHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]