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The map label for this gene is cutL [H]

Identifier: 73537625

GI number: 73537625

Start: 391516

End: 393897

Strand: Direct

Name: cutL [H]

Synonym: Reut_B3790

Alternate gene names: 73537625

Gene position: 391516-393897 (Clockwise)

Preceding gene: 73537624

Following gene: 73537626

Centisome position: 14.36

GC content: 65.45

Gene sequence:

>2382_bases
ATGGAACCGAATCATTCAGAGGAAGGGCGGGGCCAGGGGGTCGGCGCGCGTGTCGCGCGCAAGGAAGACGCCCGGCATCT
GCACGGCAAGGGCCGGTTCGTGGCGGATATCGCCATGCCGGACCTGCAGGAAGTGGCATTCCTGCGCAGTCCTGTGGCGC
ATGCAAGGCTGCTCGCGGTGACGAAGCCGCAGGGTCTGGCCGCGTCCGTGATCGTGCGCGAGGACATGCAAGAGGCCAAG
GACATCGTCGCCGACTCGGCGTTTCCGTCCTATCAGCCTTCGGCGCAGCCGCCGCTGGCCAGCGGCAAGGTGCGCTTCGT
CGGCGAACCCGTGGCGATGGCGTTCGCGCCGACCCGCGCCGAGGCGGAGGACATCGCCGAACAAGTCTCGCTTGAACTGG
ACGAGCTGACTGCGCTGACCGAAGTCGCGCAGGCGCAGCAACTGGCGGGCGAGGTCCGCGTGCACGAGCACTGGCGCGAC
AACAACTTCCTGACGCTCACCGCCGACAAGAATTTCGAAGCGCGGCAGCGCGAGGCAACCGTCGTGGTGCACCGCAAGAT
CGACCTGGCGCGCCAGTGCATGGTGCCGATGGAAGGCAAGGCGGTACTGGCCTATTGGGACCACCAGTTCGACCAGCTCG
TCGTGTACAGCGCCACGCAGGTGCCGCATATGATCCGCACGATCCTGAGCCACTGCCTCGGATTGGAGCAGGAACGCGTG
CGCGTGATCTCGCCCGATGTGGGCGGTGCGTTCGGCTACAAGTGTGTGCTGCAGCAGGAGGAGCTCTGCATCGCGTGGCT
GGCCATGACATACAAGCGGCCATTCCGCTTTATCGAGGACCGGCGCGAGCACCTGACCGCCGGGGCCAATTCGCGCGAGC
ACCACTATGAACTGACGGCCTACGCCGATGCGCGCGGCAGGCTGCTGGCGCTGGACGCGAAGATCGCGATCGACGGCGGT
GCCTACTCTGTCTGGCCATTCACCATTGGCCTGGAGCCGGGACAGGCCATCGGCAACCTGCCGGGTCCGTATGCGTTCGA
CGCCTATCGCTGCGAGACTGTTTGCGTCGCCACCAACAAGCCCGGCTTCGTGCCGTACCGCGGCGTGGCGCGCACGGGCG
TGTGCTTTGCGATGGAATTGCTGATCGACGCCATTGCCCGCGAAGTCGGCCGTGAACCTTGGGAAGTCCGTTGCGAGAAC
GTCGTGCCGCCGCAGGCCATGCCCTACGTCAACGTGACCAACAAGCATTTCGACAGCGGCGACTATCCCGCCAGCGTGCG
CAAGGCGATGGAGATGATCGACCTGGCGGGGATCCGCGCGCGCCAGAAGGCCGGCCCGGAAGGAAGTCGTTACGTGGGCG
TGGGCTTCGGCACTTACACCGAACAATCGGCTCACGGTACGTCGGTGTTCGCGGCATGGGGCACGCCGGTGATTCCGGGC
TTCGATTCCGCCACCGTGCGCATCACGCCCGATGGCGGCCTGGAAGTCCGCGTAGGCGTGCATTCGCATGGCCAGGGCAT
GGAAACAACGTTCGCGCAGATTGCCAATGAAATCCTCGGCGTCGATGTCGCACGGATCAAGGTCGTCCATGGCGATACGG
GACTGACGCCGTTTTCGACGGGCACCTACGCATCGCGTTCGCTGGTGATGTCGGGCGGCGCGGTGTCGCGCGCCTGCAAG
GCGCTGCTGCCGCGGCTGCTGAAGATCGGCGCGCACATGCTCGGCCAGCCAGAGGAGTCCGCGCGATTCGAGGCGGGACA
CGTGCGCGCGGGGGAAGCCAGCATCGCCGTCAATCGCATCGCAGACGCCTGGTACATCAACCCACACCTGTTGCCGTCCG
ACGTCGATGCACAAGGGCTGGAAACGACCATGGGCTTCAAGCCGGCCGTCGATACGGGCAGCTTCACCTATGCCACGCAT
GCGGTCGCCGTGGAGGTCGATGTCGATTCCGGCCACGTCGAGATTCTCGACTACGTGGTCGTCGAGGACTGCGGCACCAT
GATCAATCCAATGGTCGTGGAGGGCCAGACCTACGGTGGCGTGGCGCAGGGCATCGGTACCGCGATGTTCGAAGAGATGC
GCTACGACGGCAATGGCCAGCCGCTCGCGTCGACGCTGGCGGACTACATGCTGCCGGGACCGACCGAGATTCCGTCGATC
CGCATCCACCATTTCGAAACGCCGTCGCCGCATACGGAGTTCGGTGCGAAAGGCATGGGCGAGGGCGGTGCCATCGCGCC
GCCGGCCGCGATCTTCAATGCCGTGAACGATGCGCTGCGCGATTTCGGCGTCGAACTCAAGGAAACCCCGCTGACCCCAC
GGAAGGTGTTGGAGGCACTGGATGCCGCTGCCGCACAGTCCGAAAGCAGGAAGGCTGCCTGA

Upstream 100 bases:

>100_bases
GGCCACGGTCCTTAGCATTTTGGTCAGTATGCTGAGTATGTGAAGGGTCGCGGCGGGCACTTCGCCCGCCGTGGCCGCCG
GCCACGAAGACAGGACATCG

Downstream 100 bases:

>100_bases
CCGATGAAAGCCGTCGCTTTTTCCTATCAAGCCCCGGGCTCGCTCGCCGATGCGCTCGCGCGTCTTGGCGCGGGCACCGA
CGTTGCCAAGACCATGGGCG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MEPNHSEEGRGQGVGARVARKEDARHLHGKGRFVADIAMPDLQEVAFLRSPVAHARLLAVTKPQGLAASVIVREDMQEAK
DIVADSAFPSYQPSAQPPLASGKVRFVGEPVAMAFAPTRAEAEDIAEQVSLELDELTALTEVAQAQQLAGEVRVHEHWRD
NNFLTLTADKNFEARQREATVVVHRKIDLARQCMVPMEGKAVLAYWDHQFDQLVVYSATQVPHMIRTILSHCLGLEQERV
RVISPDVGGAFGYKCVLQQEELCIAWLAMTYKRPFRFIEDRREHLTAGANSREHHYELTAYADARGRLLALDAKIAIDGG
AYSVWPFTIGLEPGQAIGNLPGPYAFDAYRCETVCVATNKPGFVPYRGVARTGVCFAMELLIDAIAREVGREPWEVRCEN
VVPPQAMPYVNVTNKHFDSGDYPASVRKAMEMIDLAGIRARQKAGPEGSRYVGVGFGTYTEQSAHGTSVFAAWGTPVIPG
FDSATVRITPDGGLEVRVGVHSHGQGMETTFAQIANEILGVDVARIKVVHGDTGLTPFSTGTYASRSLVMSGGAVSRACK
ALLPRLLKIGAHMLGQPEESARFEAGHVRAGEASIAVNRIADAWYINPHLLPSDVDAQGLETTMGFKPAVDTGSFTYATH
AVAVEVDVDSGHVEILDYVVVEDCGTMINPMVVEGQTYGGVAQGIGTAMFEEMRYDGNGQPLASTLADYMLPGPTEIPSI
RIHHFETPSPHTEFGAKGMGEGGAIAPPAAIFNAVNDALRDFGVELKETPLTPRKVLEALDAAAAQSESRKAA

Sequences:

>Translated_793_residues
MEPNHSEEGRGQGVGARVARKEDARHLHGKGRFVADIAMPDLQEVAFLRSPVAHARLLAVTKPQGLAASVIVREDMQEAK
DIVADSAFPSYQPSAQPPLASGKVRFVGEPVAMAFAPTRAEAEDIAEQVSLELDELTALTEVAQAQQLAGEVRVHEHWRD
NNFLTLTADKNFEARQREATVVVHRKIDLARQCMVPMEGKAVLAYWDHQFDQLVVYSATQVPHMIRTILSHCLGLEQERV
RVISPDVGGAFGYKCVLQQEELCIAWLAMTYKRPFRFIEDRREHLTAGANSREHHYELTAYADARGRLLALDAKIAIDGG
AYSVWPFTIGLEPGQAIGNLPGPYAFDAYRCETVCVATNKPGFVPYRGVARTGVCFAMELLIDAIAREVGREPWEVRCEN
VVPPQAMPYVNVTNKHFDSGDYPASVRKAMEMIDLAGIRARQKAGPEGSRYVGVGFGTYTEQSAHGTSVFAAWGTPVIPG
FDSATVRITPDGGLEVRVGVHSHGQGMETTFAQIANEILGVDVARIKVVHGDTGLTPFSTGTYASRSLVMSGGAVSRACK
ALLPRLLKIGAHMLGQPEESARFEAGHVRAGEASIAVNRIADAWYINPHLLPSDVDAQGLETTMGFKPAVDTGSFTYATH
AVAVEVDVDSGHVEILDYVVVEDCGTMINPMVVEGQTYGGVAQGIGTAMFEEMRYDGNGQPLASTLADYMLPGPTEIPSI
RIHHFETPSPHTEFGAKGMGEGGAIAPPAAIFNAVNDALRDFGVELKETPLTPRKVLEALDAAAAQSESRKAA
>Mature_793_residues
MEPNHSEEGRGQGVGARVARKEDARHLHGKGRFVADIAMPDLQEVAFLRSPVAHARLLAVTKPQGLAASVIVREDMQEAK
DIVADSAFPSYQPSAQPPLASGKVRFVGEPVAMAFAPTRAEAEDIAEQVSLELDELTALTEVAQAQQLAGEVRVHEHWRD
NNFLTLTADKNFEARQREATVVVHRKIDLARQCMVPMEGKAVLAYWDHQFDQLVVYSATQVPHMIRTILSHCLGLEQERV
RVISPDVGGAFGYKCVLQQEELCIAWLAMTYKRPFRFIEDRREHLTAGANSREHHYELTAYADARGRLLALDAKIAIDGG
AYSVWPFTIGLEPGQAIGNLPGPYAFDAYRCETVCVATNKPGFVPYRGVARTGVCFAMELLIDAIAREVGREPWEVRCEN
VVPPQAMPYVNVTNKHFDSGDYPASVRKAMEMIDLAGIRARQKAGPEGSRYVGVGFGTYTEQSAHGTSVFAAWGTPVIPG
FDSATVRITPDGGLEVRVGVHSHGQGMETTFAQIANEILGVDVARIKVVHGDTGLTPFSTGTYASRSLVMSGGAVSRACK
ALLPRLLKIGAHMLGQPEESARFEAGHVRAGEASIAVNRIADAWYINPHLLPSDVDAQGLETTMGFKPAVDTGSFTYATH
AVAVEVDVDSGHVEILDYVVVEDCGTMINPMVVEGQTYGGVAQGIGTAMFEEMRYDGNGQPLASTLADYMLPGPTEIPSI
RIHHFETPSPHTEFGAKGMGEGGAIAPPAAIFNAVNDALRDFGVELKETPLTPRKVLEALDAAAAQSESRKAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=790, Percent_Identity=23.6708860759494, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI91823271, Length=711, Percent_Identity=22.5035161744023, Blast_Score=97, Evalue=5e-20,
Organism=Escherichia coli, GI1789230, Length=773, Percent_Identity=27.0375161707633, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1789246, Length=833, Percent_Identity=26.4105642256903, Blast_Score=193, Evalue=4e-50,
Organism=Escherichia coli, GI1786478, Length=631, Percent_Identity=25.1980982567353, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540638, Length=792, Percent_Identity=22.4747474747475, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24647193, Length=715, Percent_Identity=23.3566433566434, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17737937, Length=678, Percent_Identity=23.598820058997, Blast_Score=101, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85826; Mature: 85826

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPNHSEEGRGQGVGARVARKEDARHLHGKGRFVADIAMPDLQEVAFLRSPVAHARLLAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCHHHEEEEEE
TKPQGLAASVIVREDMQEAKDIVADSAFPSYQPSAQPPLASGKVRFVGEPVAMAFAPTRA
ECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCC
EAEDIAEQVSLELDELTALTEVAQAQQLAGEVRVHEHWRDNNFLTLTADKNFEARQREAT
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCCCCCCEE
VVVHRKIDLARQCMVPMEGKAVLAYWDHQFDQLVVYSATQVPHMIRTILSHCLGLEQERV
EEEEEHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCE
RVISPDVGGAFGYKCVLQQEELCIAWLAMTYKRPFRFIEDRREHLTAGANSREHHYELTA
EEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
YADARGRLLALDAKIAIDGGAYSVWPFTIGLEPGQAIGNLPGPYAFDAYRCETVCVATNK
EECCCCCEEEEEEEEEECCCCEEEEEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECCC
PGFVPYRGVARTGVCFAMELLIDAIAREVGREPWEVRCENVVPPQAMPYVNVTNKHFDSG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCCCCCC
DYPASVRKAMEMIDLAGIRARQKAGPEGSRYVGVGFGTYTEQSAHGTSVFAAWGTPVIPG
CCCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCC
FDSATVRITPDGGLEVRVGVHSHGQGMETTFAQIANEILGVDVARIKVVHGDTGLTPFST
CCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCC
GTYASRSLVMSGGAVSRACKALLPRLLKIGAHMLGQPEESARFEAGHVRAGEASIAVNRI
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCEECCCHHHHHHHH
ADAWYINPHLLPSDVDAQGLETTMGFKPAVDTGSFTYATHAVAVEVDVDSGHVEILDYVV
CCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEEEEEECCCCCEEHHHHHH
VEDCGTMINPMVVEGQTYGGVAQGIGTAMFEEMRYDGNGQPLASTLADYMLPGPTEIPSI
HHHHCHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEE
RIHHFETPSPHTEFGAKGMGEGGAIAPPAAIFNAVNDALRDFGVELKETPLTPRKVLEAL
EEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
DAAAAQSESRKAA
HHHHHHCCCCCCC
>Mature Secondary Structure
MEPNHSEEGRGQGVGARVARKEDARHLHGKGRFVADIAMPDLQEVAFLRSPVAHARLLAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCHHHEEEEEE
TKPQGLAASVIVREDMQEAKDIVADSAFPSYQPSAQPPLASGKVRFVGEPVAMAFAPTRA
ECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCC
EAEDIAEQVSLELDELTALTEVAQAQQLAGEVRVHEHWRDNNFLTLTADKNFEARQREAT
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCCCCCCEE
VVVHRKIDLARQCMVPMEGKAVLAYWDHQFDQLVVYSATQVPHMIRTILSHCLGLEQERV
EEEEEHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCE
RVISPDVGGAFGYKCVLQQEELCIAWLAMTYKRPFRFIEDRREHLTAGANSREHHYELTA
EEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
YADARGRLLALDAKIAIDGGAYSVWPFTIGLEPGQAIGNLPGPYAFDAYRCETVCVATNK
EECCCCCEEEEEEEEEECCCCEEEEEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECCC
PGFVPYRGVARTGVCFAMELLIDAIAREVGREPWEVRCENVVPPQAMPYVNVTNKHFDSG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCCCCCC
DYPASVRKAMEMIDLAGIRARQKAGPEGSRYVGVGFGTYTEQSAHGTSVFAAWGTPVIPG
CCCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCC
FDSATVRITPDGGLEVRVGVHSHGQGMETTFAQIANEILGVDVARIKVVHGDTGLTPFST
CCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCC
GTYASRSLVMSGGAVSRACKALLPRLLKIGAHMLGQPEESARFEAGHVRAGEASIAVNRI
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCEECCCHHHHHHHH
ADAWYINPHLLPSDVDAQGLETTMGFKPAVDTGSFTYATHAVAVEVDVDSGHVEILDYVV
CCEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEEEEEECCCCCEEHHHHHH
VEDCGTMINPMVVEGQTYGGVAQGIGTAMFEEMRYDGNGQPLASTLADYMLPGPTEIPSI
HHHHCHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEE
RIHHFETPSPHTEFGAKGMGEGGAIAPPAAIFNAVNDALRDFGVELKETPLTPRKVLEAL
EEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHH
DAAAAQSESRKAA
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]