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The map label for this gene is actP [H]

Identifier: 73537578

GI number: 73537578

Start: 336114

End: 337778

Strand: Direct

Name: actP [H]

Synonym: Reut_B3743

Alternate gene names: 73537578

Gene position: 336114-337778 (Clockwise)

Preceding gene: 73537577

Following gene: 73537579

Centisome position: 12.33

GC content: 64.8

Gene sequence:

>1665_bases
ATGAAGCCGACTCTTCGCAAACTGCCTCTTCTCATCATGAGCCTGGCAAGTGGCGCTGCGCTGGCGGCGCCTGCCATCCA
GGGCGAGGTCACGCGCCGGCCGCTGAACTGGAGCGCCATCGTGATGTTCATGCTGTTCGTGCTGTTCACGCTCGGCATCA
CGCGCTGGGCCGCGCGGCGCACGAAATCAGCGTCGGACTTCTATGCGGCCGGAGGCGGCCTGACCGGCTTCCAGAACGGC
CTCGCGATTGCGGGCGACATGGTCTCGGCCGCATCGTTCCTCGGCATCTCGGCAATGATGTTCGACAAGGGCTATGACGG
GCTGATCTACGCGCTCGGCGTGGTCGCCGGCTGGCCCATCATCCTGTTCATCGTGGCCGAGCGGCTGCGCAACCTGGGCC
GCTATACGTTTGCCGACGTCGTGTCGTACCGCCTGTCGCAGAAGCCCGTGCGCATCACGGCCGCATTCGGCACGTTGACC
GTCGTGATCATGTACCTGGTCGCGCAGATGGTTGGGGCCGGCAAGCTGATTGAACTGCTGTTCGGCACCAGCTATGAATC
GGCCGTGGTCGTCGTCGGCCTGCTGATGGTGCTGTACGTGCTGTTCGGCGGCATGCTGGCGACGACCTGGGTGCAGATCA
TCAAGGCCGTGCTGCTGCTGGGCGGCGTCACGTTCATGGCGTTCATGGTGCTGGCGTACTTCGACTACAGCCCCGAAGCG
ATGTTCGCGGGCGCGGCGAAGGTGCATGACAAGGGACTCGCCATCCTGTCGCCCGGCGGCCTCGTGTCGAACCCGATCGA
CGCCATTTCGCTGGGCGTGGGCATGATGTTCGGCACGGCCGGTCTGCCGCATATCCTGATGCGCTTCTTCACGGTCGCGG
ATGCGCGTGAAGCGCGCAAGTCGGTGCTCTATGCGACCGGTTTTATCGGCTACTTCTACGTGCTGATCCTCGTGGTGGGC
TTCGGCGCTATCGTCATGGTCGGGAGCGATCCCGCCTACCGCGATGCCGCGGGCAAGCTCATCGGCGGCAGCAATATGGT
GGCGGTGCATCTCGCGCATGCCATCGGTGGTGACCTGTTCCTCGGCTTCATCTCGGCGGTGGCGTTCGCGACCATCCTCG
CGGTGGTGGCGGGCCTGGCGCTTTCGGGGGCCTCGGCGGTGTCGCACGACTTGTACGCCAATGTGTTCCGCAAAGGACAG
GCGAACGAGAAGGACGAGATTCGCGTCTCGAAGGCGGCCACGCTGGTCATCGGCCTGCTGGCGATGGTGCTCGGCGTGCT
GTTCGAGAAGCAGAATATCGCCTTCCTGTCCGGGCTCGTGCTGGCTATTGCCGCTTCGGTCAACTTCCCGGTGCTGTTCC
TGTCGATGTTCTGGAAGGGACTGACCACGAAGGGCGCCGTTGCGGGAAGCCTCGCGGGACTCGCATCGGCGGTGGCGCTG
CTGGTGCTCGGCCCCACGGTGTGGGTCGGCCTGCTGCACCATGACAAGCCGATCTTCCCGTATGCGAATCCGGCGTTGTT
CTCGATGACGCTTGCGTTCGTCTCCGCGTGGCTCGTGTCGGTGCTGGACAACTCGGCGCAGGCTGCTGCGGAGCGGCGTC
GCTTTGGCGCGCAGTTCGTGCGGTCGATGACGGGGATCGGGGCTGCGGGGGCATCGCAGCATTGA

Upstream 100 bases:

>100_bases
GCATCATCGTGGCTGCCATCGTGCTGACTGCGGTCTACGTGCGTCGGGCCAATACCGAGCTGGACCCGATCAACGAACGC
CTGCGCAAGGAGTGCCAAGC

Downstream 100 bases:

>100_bases
GAATTCCCGACGGCGCCAATCATGCATGGGTCGGGTTGCTCCCTCTCCCACTTCTGGAGAGCGGAGTTACGCTTTGCGTA
GTTGTTGCCGGCGCGCTCCC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MKPTLRKLPLLIMSLASGAALAAPAIQGEVTRRPLNWSAIVMFMLFVLFTLGITRWAARRTKSASDFYAAGGGLTGFQNG
LAIAGDMVSAASFLGISAMMFDKGYDGLIYALGVVAGWPIILFIVAERLRNLGRYTFADVVSYRLSQKPVRITAAFGTLT
VVIMYLVAQMVGAGKLIELLFGTSYESAVVVVGLLMVLYVLFGGMLATTWVQIIKAVLLLGGVTFMAFMVLAYFDYSPEA
MFAGAAKVHDKGLAILSPGGLVSNPIDAISLGVGMMFGTAGLPHILMRFFTVADAREARKSVLYATGFIGYFYVLILVVG
FGAIVMVGSDPAYRDAAGKLIGGSNMVAVHLAHAIGGDLFLGFISAVAFATILAVVAGLALSGASAVSHDLYANVFRKGQ
ANEKDEIRVSKAATLVIGLLAMVLGVLFEKQNIAFLSGLVLAIAASVNFPVLFLSMFWKGLTTKGAVAGSLAGLASAVAL
LVLGPTVWVGLLHHDKPIFPYANPALFSMTLAFVSAWLVSVLDNSAQAAAERRRFGAQFVRSMTGIGAAGASQH

Sequences:

>Translated_554_residues
MKPTLRKLPLLIMSLASGAALAAPAIQGEVTRRPLNWSAIVMFMLFVLFTLGITRWAARRTKSASDFYAAGGGLTGFQNG
LAIAGDMVSAASFLGISAMMFDKGYDGLIYALGVVAGWPIILFIVAERLRNLGRYTFADVVSYRLSQKPVRITAAFGTLT
VVIMYLVAQMVGAGKLIELLFGTSYESAVVVVGLLMVLYVLFGGMLATTWVQIIKAVLLLGGVTFMAFMVLAYFDYSPEA
MFAGAAKVHDKGLAILSPGGLVSNPIDAISLGVGMMFGTAGLPHILMRFFTVADAREARKSVLYATGFIGYFYVLILVVG
FGAIVMVGSDPAYRDAAGKLIGGSNMVAVHLAHAIGGDLFLGFISAVAFATILAVVAGLALSGASAVSHDLYANVFRKGQ
ANEKDEIRVSKAATLVIGLLAMVLGVLFEKQNIAFLSGLVLAIAASVNFPVLFLSMFWKGLTTKGAVAGSLAGLASAVAL
LVLGPTVWVGLLHHDKPIFPYANPALFSMTLAFVSAWLVSVLDNSAQAAAERRRFGAQFVRSMTGIGAAGASQH
>Mature_554_residues
MKPTLRKLPLLIMSLASGAALAAPAIQGEVTRRPLNWSAIVMFMLFVLFTLGITRWAARRTKSASDFYAAGGGLTGFQNG
LAIAGDMVSAASFLGISAMMFDKGYDGLIYALGVVAGWPIILFIVAERLRNLGRYTFADVVSYRLSQKPVRITAAFGTLT
VVIMYLVAQMVGAGKLIELLFGTSYESAVVVVGLLMVLYVLFGGMLATTWVQIIKAVLLLGGVTFMAFMVLAYFDYSPEA
MFAGAAKVHDKGLAILSPGGLVSNPIDAISLGVGMMFGTAGLPHILMRFFTVADAREARKSVLYATGFIGYFYVLILVVG
FGAIVMVGSDPAYRDAAGKLIGGSNMVAVHLAHAIGGDLFLGFISAVAFATILAVVAGLALSGASAVSHDLYANVFRKGQ
ANEKDEIRVSKAATLVIGLLAMVLGVLFEKQNIAFLSGLVLAIAASVNFPVLFLSMFWKGLTTKGAVAGSLAGLASAVAL
LVLGPTVWVGLLHHDKPIFPYANPALFSMTLAFVSAWLVSVLDNSAQAAAERRRFGAQFVRSMTGIGAAGASQH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=452, Percent_Identity=22.1238938053097, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1790503, Length=536, Percent_Identity=67.5373134328358, Blast_Score=742, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=463, Percent_Identity=26.9978401727862, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082237, Length=437, Percent_Identity=20.3661327231121, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58315; Mature: 58315

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA