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The map label for this gene is tsr [H]

Identifier: 73537566

GI number: 73537566

Start: 323947

End: 325488

Strand: Direct

Name: tsr [H]

Synonym: Reut_B3731

Alternate gene names: 73537566

Gene position: 323947-325488 (Clockwise)

Preceding gene: 73537564

Following gene: 73537570

Centisome position: 11.88

GC content: 65.89

Gene sequence:

>1542_bases
ATGAAGAATTTCGGAATCGGGGTACGCCTCGGCATTGGCTTTGGCGTGGTGTTGGTGCTTTGCGCGTTGATGTCCGCATT
CGGCATCATGCGCCTGCAGCAGGTGGCGGAGCGCACGCATGACATGATGCAGCAGCCGCTGACGAAGGAGCGCCTGGTCA
GCGACTGGTATCGCCTGATGCATACCAGCGTGCGCCGTACCACGGCGGTGGCCAAGAGCGCGGATCCGTCGCTGGGCGCG
TTCTTCGCGAAGGAAACCAAGGCGTCGCTCGAAGGCATTGCGGCGCTGCGCGACAAGATGCAGCCGATGCTGACATCCGA
GGCCGAGAAGGCCGCGTTCGCGAAGATCCTGCAGGTGCGTGAGCCGTACAACGCCTCGCGCGACAAGATCACCAAGCTCA
AGCAGGAAGGGCTGACCGAGGAAGCCAACGCGGTACTCGAGAAAGAGTTCGTGCCCGCCGGCGATGCCTACCTGGCCGAG
ATCCAGAAGCTGCTCGACATCCAGCGCACCAGCATCGACGCGACGGCTGCCGAGATCAACACCATCTACGTCAATGCGCG
CAACAGCCTGATTCTGCTGGGCGTGCTGGTGCTGGCCATCGGCGTTGGTTTCGCCGTGTGGCTGACGCGCGGCATCATCC
GCCCGCTGGGCCATGCCGTCGATATCGCGCGCACCGTGGCGTCGGGCGACCTGACCAGCGACATCCGCGTAGATAGCCAG
GACGAGACTGGCCAGCTGCTGCACGCACTGTCGGAGATGAATACCAACATCCTGCACATCGTGCGCGACGTGCGCACCGG
CACCGAGGCCATTGCCTCCGGCACCAGCCAGATCGCCGTGGGCAACACCGACCTGTCGCAGCGTACGGAAGAGCAGGCGT
CGTCGCTGCAGCAGACCGCGGCCAGCATGGAAGAGCTGACCAGCATCGTGCGCCAGAACGCCGACAACGCGAAGCAGGCC
AGCGCGCTGGCCGTGAACGCGTCGGAGATCGCGGCCAAGGGCGGCGACGTGGCCGACAAGGTCGCCGAGACCATGGAAGA
GATCAACGGCGCGTCGAAGAAGGTGGTCGACATCATCGCCGTGATCGAAGGCATCGCGTTCCAGACCAACATCCTGGCGC
TGAACGCCGCGGTGGAAGCCGCGCGCGCGGGCGAGCAGGGCCGCGGCTTTGCGGTGGTGGCGGGCGAGGTGCGCAGCCTG
GCCCAGCGCAGCGCTACCGCTGCCAAGGAAATCAAGGCGCTGATCGGCGACTCGGTCGACCGCGTGGAGAAGGGCTCGAC
CCTCGTGGCGCAATCGGGCCAGACCATGCTGGAGATCGTGGAAGCGGTCAGGCGCGTGACGGACATCATGGGCGAGATCA
GCGCGGCGTCGGCGGAGCAGAGCGCCGGCATCGAGCAGGTCAACCAGGCCGTGACGCAGATGGATTCGGTCACGCAGCAG
AACGCCGCGCTGGTGGAAGAGGCGGCTGCGGCGGCCGGCTCGCTGGAGGAGCAGGCGCAGCGGTTGAAGCAGGCGGTGGC
TACGTTTCGTATTGCGGCCTGA

Upstream 100 bases:

>100_bases
GCCACAGTCCCTGTCCAGGTCGGCGGGCCACGAGAGCGAAAGGCGGCGTCCGCGCGCCAGCACTTCGCCGTATCGAAGTC
CAGATCAGGTAGAAGAAATA

Downstream 100 bases:

>100_bases
CGCTGCATCGATAGCCTGAAAGAACAAGGCCCGGCGTCTGCCGGGCCTCTTATTTAGCGCGCCTTCAGAAACTCCCCGAC
TTCCAGCAACACCAGCTCGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKNFGIGVRLGIGFGVVLVLCALMSAFGIMRLQQVAERTHDMMQQPLTKERLVSDWYRLMHTSVRRTTAVAKSADPSLGA
FFAKETKASLEGIAALRDKMQPMLTSEAEKAAFAKILQVREPYNASRDKITKLKQEGLTEEANAVLEKEFVPAGDAYLAE
IQKLLDIQRTSIDATAAEINTIYVNARNSLILLGVLVLAIGVGFAVWLTRGIIRPLGHAVDIARTVASGDLTSDIRVDSQ
DETGQLLHALSEMNTNILHIVRDVRTGTEAIASGTSQIAVGNTDLSQRTEEQASSLQQTAASMEELTSIVRQNADNAKQA
SALAVNASEIAAKGGDVADKVAETMEEINGASKKVVDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSL
AQRSATAAKEIKALIGDSVDRVEKGSTLVAQSGQTMLEIVEAVRRVTDIMGEISAASAEQSAGIEQVNQAVTQMDSVTQQ
NAALVEEAAAAAGSLEEQAQRLKQAVATFRIAA

Sequences:

>Translated_513_residues
MKNFGIGVRLGIGFGVVLVLCALMSAFGIMRLQQVAERTHDMMQQPLTKERLVSDWYRLMHTSVRRTTAVAKSADPSLGA
FFAKETKASLEGIAALRDKMQPMLTSEAEKAAFAKILQVREPYNASRDKITKLKQEGLTEEANAVLEKEFVPAGDAYLAE
IQKLLDIQRTSIDATAAEINTIYVNARNSLILLGVLVLAIGVGFAVWLTRGIIRPLGHAVDIARTVASGDLTSDIRVDSQ
DETGQLLHALSEMNTNILHIVRDVRTGTEAIASGTSQIAVGNTDLSQRTEEQASSLQQTAASMEELTSIVRQNADNAKQA
SALAVNASEIAAKGGDVADKVAETMEEINGASKKVVDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSL
AQRSATAAKEIKALIGDSVDRVEKGSTLVAQSGQTMLEIVEAVRRVTDIMGEISAASAEQSAGIEQVNQAVTQMDSVTQQ
NAALVEEAAAAAGSLEEQAQRLKQAVATFRIAA
>Mature_513_residues
MKNFGIGVRLGIGFGVVLVLCALMSAFGIMRLQQVAERTHDMMQQPLTKERLVSDWYRLMHTSVRRTTAVAKSADPSLGA
FFAKETKASLEGIAALRDKMQPMLTSEAEKAAFAKILQVREPYNASRDKITKLKQEGLTEEANAVLEKEFVPAGDAYLAE
IQKLLDIQRTSIDATAAEINTIYVNARNSLILLGVLVLAIGVGFAVWLTRGIIRPLGHAVDIARTVASGDLTSDIRVDSQ
DETGQLLHALSEMNTNILHIVRDVRTGTEAIASGTSQIAVGNTDLSQRTEEQASSLQQTAASMEELTSIVRQNADNAKQA
SALAVNASEIAAKGGDVADKVAETMEEINGASKKVVDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSL
AQRSATAAKEIKALIGDSVDRVEKGSTLVAQSGQTMLEIVEAVRRVTDIMGEISAASAEQSAGIEQVNQAVTQMDSVTQQ
NAALVEEAAAAAGSLEEQAQRLKQAVATFRIAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=386, Percent_Identity=56.2176165803109, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1788195, Length=309, Percent_Identity=61.8122977346278, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1787690, Length=507, Percent_Identity=44.1814595660749, Blast_Score=321, Evalue=8e-89,
Organism=Escherichia coli, GI1788194, Length=321, Percent_Identity=56.0747663551402, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1789453, Length=322, Percent_Identity=39.1304347826087, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 54552; Mature: 54552

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFGIGVRLGIGFGVVLVLCALMSAFGIMRLQQVAERTHDMMQQPLTKERLVSDWYRLM
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HTSVRRTTAVAKSADPSLGAFFAKETKASLEGIAALRDKMQPMLTSEAEKAAFAKILQVR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EPYNASRDKITKLKQEGLTEEANAVLEKEFVPAGDAYLAEIQKLLDIQRTSIDATAAEIN
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHEE
TIYVNARNSLILLGVLVLAIGVGFAVWLTRGIIRPLGHAVDIARTVASGDLTSDIRVDSQ
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DETGQLLHALSEMNTNILHIVRDVRTGTEAIASGTSQIAVGNTDLSQRTEEQASSLQQTA
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHH
ASMEELTSIVRQNADNAKQASALAVNASEIAAKGGDVADKVAETMEEINGASKKVVDIIA
HHHHHHHHHHHCCCCCHHHHHHHEECHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHH
VIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSATAAKEIKALIGDSVD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHH
RVEKGSTLVAQSGQTMLEIVEAVRRVTDIMGEISAASAEQSAGIEQVNQAVTQMDSVTQQ
HHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
NAALVEEAAAAAGSLEEQAQRLKQAVATFRIAA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNFGIGVRLGIGFGVVLVLCALMSAFGIMRLQQVAERTHDMMQQPLTKERLVSDWYRLM
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HTSVRRTTAVAKSADPSLGAFFAKETKASLEGIAALRDKMQPMLTSEAEKAAFAKILQVR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EPYNASRDKITKLKQEGLTEEANAVLEKEFVPAGDAYLAEIQKLLDIQRTSIDATAAEIN
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHEE
TIYVNARNSLILLGVLVLAIGVGFAVWLTRGIIRPLGHAVDIARTVASGDLTSDIRVDSQ
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DETGQLLHALSEMNTNILHIVRDVRTGTEAIASGTSQIAVGNTDLSQRTEEQASSLQQTA
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHH
ASMEELTSIVRQNADNAKQASALAVNASEIAAKGGDVADKVAETMEEINGASKKVVDIIA
HHHHHHHHHHHCCCCCHHHHHHHEECHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHH
VIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSATAAKEIKALIGDSVD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHH
RVEKGSTLVAQSGQTMLEIVEAVRRVTDIMGEISAASAEQSAGIEQVNQAVTQMDSVTQQ
HHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHH
NAALVEEAAAAAGSLEEQAQRLKQAVATFRIAA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]