BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is hbdH1 [H]

Identifier: 73537564

GI number: 73537564

Start: 322324

End: 323100

Strand: Direct

Name: hbdH1 [H]

Synonym: Reut_B3729

Alternate gene names: 73537564

Gene position: 322324-323100 (Clockwise)

Preceding gene: 73537563

Following gene: 73537566

Centisome position: 11.82

GC content: 65.64

Gene sequence:

>777_bases
ATGAATACCCTGAACGGAAAGACCGCGCTCGTGACCGGTTCCACGAGCGGCATTGGCCTGGGCGTCGCCCGGGCACTGGC
CGAGGCGGGCGCCAATATCGTGCTCAACGGCTTCGGCGACGTCGATGCCGCGCTTGACACCATTGGCGCTACGGGCGCAC
AGGTCGTGCACCACCCGGCCGACATGCGCAAGGCCGACGAGATCGGCGCAATGATCGCCATGGCCAACGAGCGTTTCGGC
GCGCTGGATATCCTCGTCAACAACGCTGGCATCCAGCACGTATCGCCGATCGAAAGCTTCGATGCGCAGAAGTGGGACGA
CATCATCGCCATCAACCTGAGCTCGGGCTTTCACACCACGCGTCACGTGCTGCCCGGCATGCGGGCGCGCAACTGGGGCC
GCATCATCAATATCGCTTCGGTGCACGGGCTGGTCGGCTCGGCCGGAAAGTCGGCCTATGTGGCTGCCAAGCATGGACTC
GTCGGATTGACCAAGGTCACCGCGCTGGAGACGGCGGGCACCCGCGTGACCTGCAACGCGATCTGCCCGGGGTTCGTGCT
GACGCCGCTGGTGCAGAAGCAGATCGACGATCTCGCCGCTCGCGAGGGGATTGCTATCGATGCGGCTCGCGCGCGCCTGC
TCGGCGAGAAGCAGCCCTCGGGCCAGTTCGTCACGCCCGAGCAATTGGGCGGGCTGGCGCTGATGTTGTGTTCGCCGCTG
GCGGCCGAAGTACGAGGTGCCACATGGGTGGCTGACGGAGGTTGGACGGCGCAGTAA

Upstream 100 bases:

>100_bases
TGGCGGTGTTCTTCGTCATCCTGGTCTACTACATGACCGGCCTGGTCTGACCGTTCCGAACGTTTCCAACGTTTCCCGCA
ATTCCTGAATCCGCATTGCC

Downstream 100 bases:

>100_bases
TCGCCCCCGGCCGGAAACGACTTCCACACCACATCCATGTCCACAAACGCGAAAAGCCGGCGGACACAGCCGGCTTTTCG
CTGACCTGAACGGTCGCCCT

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNTLNGKTALVTGSTSGIGLGVARALAEAGANIVLNGFGDVDAALDTIGATGAQVVHHPADMRKADEIGAMIAMANERFG
ALDILVNNAGIQHVSPIESFDAQKWDDIIAINLSSGFHTTRHVLPGMRARNWGRIINIASVHGLVGSAGKSAYVAAKHGL
VGLTKVTALETAGTRVTCNAICPGFVLTPLVQKQIDDLAAREGIAIDAARARLLGEKQPSGQFVTPEQLGGLALMLCSPL
AAEVRGATWVADGGWTAQ

Sequences:

>Translated_258_residues
MNTLNGKTALVTGSTSGIGLGVARALAEAGANIVLNGFGDVDAALDTIGATGAQVVHHPADMRKADEIGAMIAMANERFG
ALDILVNNAGIQHVSPIESFDAQKWDDIIAINLSSGFHTTRHVLPGMRARNWGRIINIASVHGLVGSAGKSAYVAAKHGL
VGLTKVTALETAGTRVTCNAICPGFVLTPLVQKQIDDLAAREGIAIDAARARLLGEKQPSGQFVTPEQLGGLALMLCSPL
AAEVRGATWVADGGWTAQ
>Mature_258_residues
MNTLNGKTALVTGSTSGIGLGVARALAEAGANIVLNGFGDVDAALDTIGATGAQVVHHPADMRKADEIGAMIAMANERFG
ALDILVNNAGIQHVSPIESFDAQKWDDIIAINLSSGFHTTRHVLPGMRARNWGRIINIASVHGLVGSAGKSAYVAAKHGL
VGLTKVTALETAGTRVTCNAICPGFVLTPLVQKQIDDLAAREGIAIDAARARLLGEKQPSGQFVTPEQLGGLALMLCSPL
AAEVRGATWVADGGWTAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=32.421875, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=32.4607329842932, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66933014, Length=263, Percent_Identity=30.7984790874525, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=26.8199233716475, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=35.1758793969849, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=29.3436293436293, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=28.6792452830189, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=32.967032967033, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI33667109, Length=262, Percent_Identity=30.5343511450382, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI59889578, Length=181, Percent_Identity=33.1491712707182, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4758504, Length=207, Percent_Identity=31.4009661835749, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI142976729, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI20149619, Length=209, Percent_Identity=29.6650717703349, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=33.5260115606936, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=26.8, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=26.5625, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI109715829, Length=207, Percent_Identity=28.5024154589372, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=31.6666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=198, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254986, Length=242, Percent_Identity=26.0330578512397, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=28.1914893617021, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=27.979274611399, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=35.7692307692308, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=33.852140077821, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=33.8582677165354, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=34.6456692913386, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=31.1023622047244, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=30.3501945525292, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=29.7297297297297, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=29.296875, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367175, Length=190, Percent_Identity=30, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786701, Length=229, Percent_Identity=28.3842794759825, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=31.4606741573034, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=30.6201550387597, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=264, Percent_Identity=29.5454545454545, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=33.1578947368421, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=237, Percent_Identity=29.535864978903, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=33.1578947368421, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=28.6259541984733, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=209, Percent_Identity=34.4497607655502, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=26.171875, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=186, Percent_Identity=31.7204301075269, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555612, Length=234, Percent_Identity=31.1965811965812, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=27.007299270073, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=187, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=27.6119402985075, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=28.125, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=281, Percent_Identity=27.7580071174377, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=166, Percent_Identity=28.9156626506024, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=25.5474452554745, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=28.1954887218045, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=26.3940520446097, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=27.3722627737226, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=26.1029411764706, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=26.5682656826568, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=26.1818181818182, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=24.3542435424354, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=218, Percent_Identity=27.9816513761468, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=212, Percent_Identity=32.0754716981132, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=29.6482412060301, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=188, Percent_Identity=26.063829787234, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=213, Percent_Identity=25.8215962441315, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355319, Length=267, Percent_Identity=30.3370786516854, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=35.2631578947368, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=28.125, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=34.0425531914894, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=33.1578947368421, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=31.6326530612245, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357041, Length=197, Percent_Identity=29.9492385786802, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=30.5389221556886, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364892, Length=165, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=26.9035532994924, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=32.3383084577114, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=30.2564102564103, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=29.7979797979798, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581726, Length=194, Percent_Identity=27.319587628866, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=33.5078534031414, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=33.5078534031414, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640442, Length=193, Percent_Identity=32.1243523316062, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21357673, Length=246, Percent_Identity=26.0162601626016, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356301, Length=204, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=28.1853281853282, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26633; Mature: 26633

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLNGKTALVTGSTSGIGLGVARALAEAGANIVLNGFGDVDAALDTIGATGAQVVHHPA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHCCCH
DMRKADEIGAMIAMANERFGALDILVNNAGIQHVSPIESFDAQKWDDIIAINLSSGFHTT
HHHHHHHHHHEEEECCCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEECCCCCHH
RHVLPGMRARNWGRIINIASVHGLVGSAGKSAYVAAKHGLVGLTKVTALETAGTRVTCNA
HHHCCCCCCCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCEEHHHHEEEECCCCEEEECC
ICPGFVLTPLVQKQIDDLAAREGIAIDAARARLLGEKQPSGQFVTPEQLGGLALMLCSPL
CCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCEECHHHHCCCHHHHHCHH
AAEVRGATWVADGGWTAQ
HHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MNTLNGKTALVTGSTSGIGLGVARALAEAGANIVLNGFGDVDAALDTIGATGAQVVHHPA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHCCCH
DMRKADEIGAMIAMANERFGALDILVNNAGIQHVSPIESFDAQKWDDIIAINLSSGFHTT
HHHHHHHHHHEEEECCCCCCEEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEECCCCCHH
RHVLPGMRARNWGRIINIASVHGLVGSAGKSAYVAAKHGLVGLTKVTALETAGTRVTCNA
HHHCCCCCCCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCEEHHHHEEEECCCCEEEECC
ICPGFVLTPLVQKQIDDLAAREGIAIDAARARLLGEKQPSGQFVTPEQLGGLALMLCSPL
CCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCEECHHHHCCCHHHHHCHH
AAEVRGATWVADGGWTAQ
HHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA