Click here to switch to the map view.

The map label for this gene is cyoC [H]

Identifier: 73537470

GI number: 73537470

Start: 207938

End: 208633

Strand: Direct

Name: cyoC [H]

Synonym: Reut_B3635

Alternate gene names: 73537470

Gene position: 207938-208633 (Clockwise)

Preceding gene: 73537469

Following gene: 73537471

Centisome position: 7.63

GC content: 62.64

Gene sequence:

>696_bases
ATGTCATCGAACGTCTCGACACAGCCCGACGCGCCAGGTGCCGTGGCCACGGGCCTGCGCGGCCTGGTGGCGGACTGGTC
GTCGGACCAGCGCGCCTTCAAGGTGTCGTGGGGCAAGGCGATGATGTGGATCTTCCTGCTGTCCGACACCTTCGTGTTCA
GCTGCTTCCTCACGGGCTACATGACGGTGCGCATGGCGACCACGGTGCCGTGGCCCAACCCCAGCGAGGTCTTTGGCCTG
CGTATCGGCGGGCACGACGTGCCGCTGCTGCTGATCGCAATCATGACGTTCGTGCTGATCACCAGCAGCGGCACTATGGC
CATGGCGGTCAACTTCGCGTACCGGCGGCAGCGGCGGCAATGCGCGCTGCTGATGCTGGTGACCGCGCTGTTCGGCGCTA
CCTTTGTCTGCATGCAGGCCTTCGAATGGACCAAGCTGATCGTCGAGGAAGGCGTGCGCCCCTGGGGCAACCCGATGGGC
GCGCCGCAGTTCGGTTCCACCTTCTTCATGATCACCGGCTTTCATGGACTGCATGTGAGCTGCGGTGTGATCTACCTGCT
GATCGTGGCAACCAAGGTGCTGCGTGGCCGGTATGAAGTCACCGGCAATTACCAGATCGTCGAGATCGCGGGCCTGTACT
GGCACTTCGTGGACCTGGTCTGGGTGTTCATCTTTGCATTGTTCTACCTCTGGTGA

Upstream 100 bases:

>100_bases
CGTGTGGGTGGTGCTGCTGGCCGCGCTGGGCTGGCTCACGCCCGAGATCGTGCGCTATATCTGCGGTACCGCGTAGCTCC
CGGTGCCGAGGAGGATTCTC

Downstream 100 bases:

>100_bases
GGCTTGCCATGGCTTCGACTCCGACTTCCGCCGCCCCGGCTCCCGCACACGGCCACGAAGACACCGCGCACACCGGCCAG
CAGCATCCAATCGGCCTCTA

Product: cytochrome-C oxidase subunit III oxidoreductase protein

Products: Ubiquinone-8; H2O. [C]

Alternate protein names: Cytochrome o ubiquinol oxidase subunit III; Ubiquinol oxidase chain C [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSSNVSTQPDAPGAVATGLRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFVFSCFLTGYMTVRMATTVPWPNPSEVFGL
RIGGHDVPLLLIAIMTFVLITSSGTMAMAVNFAYRRQRRQCALLMLVTALFGATFVCMQAFEWTKLIVEEGVRPWGNPMG
APQFGSTFFMITGFHGLHVSCGVIYLLIVATKVLRGRYEVTGNYQIVEIAGLYWHFVDLVWVFIFALFYLW

Sequences:

>Translated_231_residues
MSSNVSTQPDAPGAVATGLRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFVFSCFLTGYMTVRMATTVPWPNPSEVFGL
RIGGHDVPLLLIAIMTFVLITSSGTMAMAVNFAYRRQRRQCALLMLVTALFGATFVCMQAFEWTKLIVEEGVRPWGNPMG
APQFGSTFFMITGFHGLHVSCGVIYLLIVATKVLRGRYEVTGNYQIVEIAGLYWHFVDLVWVFIFALFYLW
>Mature_230_residues
SSNVSTQPDAPGAVATGLRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFVFSCFLTGYMTVRMATTVPWPNPSEVFGLR
IGGHDVPLLLIAIMTFVLITSSGTMAMAVNFAYRRQRRQCALLMLVTALFGATFVCMQAFEWTKLIVEEGVRPWGNPMGA
PQFGSTFFMITGFHGLHVSCGVIYLLIVATKVLRGRYEVTGNYQIVEIAGLYWHFVDLVWVFIFALFYLW

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration [H]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=146, Percent_Identity=32.8767123287671, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786633, Length=190, Percent_Identity=33.1578947368421, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833
- InterPro:   IPR014206 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: 1.10.3.- [C]

Molecular weight: Translated: 25888; Mature: 25757

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNVSTQPDAPGAVATGLRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFVFSCFLTGY
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
MTVRMATTVPWPNPSEVFGLRIGGHDVPLLLIAIMTFVLITSSGTMAMAVNFAYRRQRRQ
HHHEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
CALLMLVTALFGATFVCMQAFEWTKLIVEEGVRPWGNPMGAPQFGSTFFMITGFHGLHVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHH
CGVIYLLIVATKVLRGRYEVTGNYQIVEIAGLYWHFVDLVWVFIFALFYLW
HHHHHHHHHHHHHHCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SSNVSTQPDAPGAVATGLRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFVFSCFLTGY
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
MTVRMATTVPWPNPSEVFGLRIGGHDVPLLLIAIMTFVLITSSGTMAMAVNFAYRRQRRQ
HHHEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHH
CALLMLVTALFGATFVCMQAFEWTKLIVEEGVRPWGNPMGAPQFGSTFFMITGFHGLHVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHH
CGVIYLLIVATKVLRGRYEVTGNYQIVEIAGLYWHFVDLVWVFIFALFYLW
HHHHHHHHHHHHHHCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ubiquinol-8; O(2) [C]

Specific reaction: Ubiquinol-8 + O(2) = Ubiquinone-8 + H2O. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]