BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is pldh-t [H]

Identifier: 73537406

GI number: 73537406

Start: 127208

End: 127978

Strand: Direct

Name: pldh-t [H]

Synonym: Reut_B3571

Alternate gene names: 73537406

Gene position: 127208-127978 (Clockwise)

Preceding gene: 73537405

Following gene: 73537407

Centisome position: 4.67

GC content: 69.78

Gene sequence:

>771_bases
ATGCCTGAGGCCAACAACAACGGCCTGCTGGCCGGGCGCAAGGTGCTGGTCACCGGCGCCGCACGCGGACTGGGCCTGGC
CTTCGTCAAGTCGCTCACTGAAGCCGGCGCCGCAGTGGCCATGGCCGACATCCTGGCCGATCGCCTGCAGCAGGAAGCCG
ACGCACTGCGCGCTCGCGGCTTCAAGGTGGTGGCCGTGCCGGTGGACCTGTCCGACCCGGCTTCCGTGCAGGCCTGTGCC
GATGCCGCCATCAAGGGCCTCGGCGGTCTGGATGGCCTGGTCAACAACGCAGCCGTGACCGATTCCGGCGGCCGTGACGC
CAGCGCCATCGACGTCGCCACCTGGGACCGCGTGATGAACGTCAACGTGCGCGGCACCTGGCTGATGACCACGGCCTGCC
TGCCGGCCCTGAAGGCCAGCGGCCGCGGCGCCGTGATCAACCTGGCTTCCGACACGCCGCTGTGGGGCGCGCCGAACCTG
CTGGCCTATGTGGCGAGCAAGAGCGCCATCATCGGCATGACGCGCTCGCTGGCGCGCGAACTGGGCCGCGACCAGATCAC
CGTCAACGCGGTGGCGCCGGGCCTGACGCTGGTGGAAGCCACCGAATACGTGCCGCAGCACCGGCACGACCTGTATCGCG
AGCAGCGCGCCATCCAGCGCGAGCAACTGCCCGACGATGTCTGCGGCGCGGTGCTGTTCGCACTGTCCGACCTCGCCCGT
TTCGTGACCGGCCAGACGCTGGCGGTCAACGGCGGCTTTGTCATGCACTGA

Upstream 100 bases:

>100_bases
GGCATCACGCGCGTGCGCCGTCTGCTGAAGCGCCGCGCCGAGCAGGAGATTGCCGATGAGCCGGTCGCCATGCTCAAGGC
TGCCGGCGGGGTGGCGAACC

Downstream 100 bases:

>100_bases
TCCACTGATCTAACGATCTACTGAAACAGAAGGAATCCAAATGAGCGATCTGTCTCAACCAGCCAATATCAAGCGTTCGT
GGGAACAACCGGACGGCGCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: tPLDH [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MPEANNNGLLAGRKVLVTGAARGLGLAFVKSLTEAGAAVAMADILADRLQQEADALRARGFKVVAVPVDLSDPASVQACA
DAAIKGLGGLDGLVNNAAVTDSGGRDASAIDVATWDRVMNVNVRGTWLMTTACLPALKASGRGAVINLASDTPLWGAPNL
LAYVASKSAIIGMTRSLARELGRDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAIQREQLPDDVCGAVLFALSDLAR
FVTGQTLAVNGGFVMH

Sequences:

>Translated_256_residues
MPEANNNGLLAGRKVLVTGAARGLGLAFVKSLTEAGAAVAMADILADRLQQEADALRARGFKVVAVPVDLSDPASVQACA
DAAIKGLGGLDGLVNNAAVTDSGGRDASAIDVATWDRVMNVNVRGTWLMTTACLPALKASGRGAVINLASDTPLWGAPNL
LAYVASKSAIIGMTRSLARELGRDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAIQREQLPDDVCGAVLFALSDLAR
FVTGQTLAVNGGFVMH
>Mature_255_residues
PEANNNGLLAGRKVLVTGAARGLGLAFVKSLTEAGAAVAMADILADRLQQEADALRARGFKVVAVPVDLSDPASVQACAD
AAIKGLGGLDGLVNNAAVTDSGGRDASAIDVATWDRVMNVNVRGTWLMTTACLPALKASGRGAVINLASDTPLWGAPNLL
AYVASKSAIIGMTRSLARELGRDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAIQREQLPDDVCGAVLFALSDLARF
VTGQTLAVNGGFVMH

Specific function: Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Oxidizes pyridoxal to 4-pyridoxolactone, but does not have activity toward pyridoxal 5'-phosphate, pyridoxine, pyridoxamine, pyridoxamine 5'-phosphat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=31.5789473684211, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=30.3501945525292, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.0395256916996, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.156862745098, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=32.9317269076305, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI40254986, Length=200, Percent_Identity=33, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=27.1255060728745, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI33667109, Length=204, Percent_Identity=30.8823529411765, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=28.0334728033473, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=30.8510638297872, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=26.7441860465116, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI142976729, Length=178, Percent_Identity=30.3370786516854, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=30.4123711340206, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=26.8, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=28.1385281385281, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=26.4550264550265, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI302344755, Length=111, Percent_Identity=36.9369369369369, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=32.6771653543307, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.8185328185328, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=30.241935483871, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=31.7647058823529, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=31.3492063492063, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=27.843137254902, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=31.7460317460317, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=28.515625, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788459, Length=209, Percent_Identity=29.6650717703349, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=32.1138211382114, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787891, Length=246, Percent_Identity=28.4552845528455, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786701, Length=205, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787820, Length=238, Percent_Identity=26.890756302521, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.5625, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=28.5140562248996, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788891, Length=193, Percent_Identity=33.6787564766839, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=28.5140562248996, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=33.4661354581673, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=30.952380952381, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=28.6259541984733, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982365, Length=200, Percent_Identity=33, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=29.8804780876494, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=32.2834645669291, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=29.0196078431373, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.8625954198473, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=25, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.6515151515151, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=25.9398496240602, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=25.830258302583, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17558628, Length=202, Percent_Identity=31.6831683168317, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=26.8939393939394, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=27.4590163934426, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=25.9541984732824, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=186, Percent_Identity=28.494623655914, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=190, Percent_Identity=34.2105263157895, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=173, Percent_Identity=28.3236994219653, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=184, Percent_Identity=28.804347826087, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=30.0970873786408, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=24.5136186770428, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=27.4131274131274, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=24.2307692307692, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=254, Percent_Identity=25.5905511811024, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=170, Percent_Identity=27.6470588235294, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=23.1939163498099, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=25.187969924812, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=26.0700389105058, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=221, Percent_Identity=26.6968325791855, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=30, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=256, Percent_Identity=27.34375, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=24.3137254901961, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=29.0836653386454, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.1587301587302, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=29.9595141700405, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=30.5220883534137, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357673, Length=199, Percent_Identity=31.1557788944724, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=31.1023622047244, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=28.2868525896414, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=35.2631578947368, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=31.1740890688259, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=31.0880829015544, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=29.5336787564767, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=232, Percent_Identity=29.7413793103448, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364892, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI161076933, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584748, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221331218, Length=218, Percent_Identity=32.5688073394495, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665243, Length=218, Percent_Identity=32.5688073394495, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=25.3807106598985, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=25.3807106598985, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.107 [H]

Molecular weight: Translated: 26683; Mature: 26552

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEANNNGLLAGRKVLVTGAARGLGLAFVKSLTEAGAAVAMADILADRLQQEADALRARG
CCCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FKVVAVPVDLSDPASVQACADAAIKGLGGLDGLVNNAAVTDSGGRDASAIDVATWDRVMN
EEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCEEEHHHHHHEEE
VNVRGTWLMTTACLPALKASGRGAVINLASDTPLWGAPNLLAYVASKSAIIGMTRSLARE
CCCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHH
LGRDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAIQREQLPDDVCGAVLFALSDLAR
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FVTGQTLAVNGGFVMH
HHCCCEEEECCCEEEC
>Mature Secondary Structure 
PEANNNGLLAGRKVLVTGAARGLGLAFVKSLTEAGAAVAMADILADRLQQEADALRARG
CCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FKVVAVPVDLSDPASVQACADAAIKGLGGLDGLVNNAAVTDSGGRDASAIDVATWDRVMN
EEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCEEEHHHHHHEEE
VNVRGTWLMTTACLPALKASGRGAVINLASDTPLWGAPNLLAYVASKSAIIGMTRSLARE
CCCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHH
LGRDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAIQREQLPDDVCGAVLFALSDLAR
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FVTGQTLAVNGGFVMH
HHCCCEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]