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The map label for this gene is 73537347

Identifier: 73537347

GI number: 73537347

Start: 52375

End: 53547

Strand: Direct

Name: 73537347

Synonym: Reut_B3512

Alternate gene names: NA

Gene position: 52375-53547 (Clockwise)

Preceding gene: 73537346

Following gene: 73537353

Centisome position: 1.92

GC content: 66.41

Gene sequence:

>1173_bases
ATGAGTCTGTCTTCTTTGCGCGGCAGCGTCGCCATCGTCGGCGTGGGCCAGGCAGGCCTGGGCGAAGCCCATGGCAAGAC
TGAAATGGAAATCCTCGTGGAGGCCGCCAAGGCCGCCGTGAAGGATGCGGGCATGTCGATGCGCGACATCGATGGCATCG
CCACCGCGAGCGTCGGCGCCACCATGTGGGTGATGCCGGTGGCCGAGTACCTCGGCATCAAGCCGAAGTTCGTCGACAGC
ACCATGATCGGCGGCTCGAGCTTCGTCTCGCACATGCTGCCCGCCATGATGGCGCTCGAAGCCGGCCTGTGCGACGCGGT
GCTGGTCTGCTACGGCAGCAACCAGCGCACCTCGACGGTGGGCCGTGCCGGCATCAGCAAAGTGCGCGCCGTGCTCGACC
CGCAGCCGTACGAGAATCCGTACCAGCCGCTGAGCCCGATCACGTCCTATGCACTGGCTGCCGCACGCCACATGCATCAG
TACGGCACCACGCGCGAACACCTGGCTGAAGTGGCCGTGGCCGCGCGCAAATGGGCGCAGCTCAATCCGGAAGCGCAGAT
GCGCGATCCGCTTTCTATCGAAGACGTGCTCAACGCGCGCATGGTGTCGGACCCGCTGTCCGTGCGTGACTGCTGCCTCG
TGACCGACGGTGCCGGCGCCTACGTGATGGTCCGCGCCGACCGCGCCAAGGACATGGCGAAGCCGCCGGTCTACGTGCTC
GGCAACGCGACAGCAACGTGGCACCGCCAGATCTCGTGCATGCCCGACGTCACCGTCACGGCAGCTAAGGAATCCGGCGA
GCGCGCCTTCGCGATGGCCGGCCTCAAGCCGTCGGATGTCGATGTGGCCGAGTTGTACGACGCGTTCACGATCAACACGC
TGCTGTTCCTCGAAGACCTTGGCTTCTGCCCGAAGGGCGAGGGCGGTCACTTCGTCAGTGGCGGTGGCATCGCCCCGGGC
GGCCGCCTGCCGGTGAACACCAACGGTGGCGGTCTGTCTTGCGTGCATCCGGGCATGTACGGCATGTTCATCACGATAGA
AGCCGTGCGCCAGCTGCGTGGCGAATGCGGTGACCGCCAGGTCAAGGACGCGGAAGTTGCCGTGGTCCACGGCAACGGCG
GCACGCTGTCGAGCCAGGCAACGGCGATCCTGGGGACGGCCGCCACGCTGTAA

Upstream 100 bases:

>100_bases
CTGTGCGCATCGGCATGCGCGTCAAGGCGCGCGTGGCGCCTGGCAAGGCAGAAGGCGAGCCCGCTCTCGTCGTGTTCGAT
CCGGTGGAGGGCTAAGCAAA

Downstream 100 bases:

>100_bases
GGCGATCCGGGTTTAAAGGGAAGAAGGCGCAACGGCGGGGAAGTCCAATCGGATTTCCCCGCCGTTGTGTTTTTGGCGGA
TGCGGTGGCGCCGGCTGTCA

Product: thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSLSSLRGSVAIVGVGQAGLGEAHGKTEMEILVEAAKAAVKDAGMSMRDIDGIATASVGATMWVMPVAEYLGIKPKFVDS
TMIGGSSFVSHMLPAMMALEAGLCDAVLVCYGSNQRTSTVGRAGISKVRAVLDPQPYENPYQPLSPITSYALAAARHMHQ
YGTTREHLAEVAVAARKWAQLNPEAQMRDPLSIEDVLNARMVSDPLSVRDCCLVTDGAGAYVMVRADRAKDMAKPPVYVL
GNATATWHRQISCMPDVTVTAAKESGERAFAMAGLKPSDVDVAELYDAFTINTLLFLEDLGFCPKGEGGHFVSGGGIAPG
GRLPVNTNGGGLSCVHPGMYGMFITIEAVRQLRGECGDRQVKDAEVAVVHGNGGTLSSQATAILGTAATL

Sequences:

>Translated_390_residues
MSLSSLRGSVAIVGVGQAGLGEAHGKTEMEILVEAAKAAVKDAGMSMRDIDGIATASVGATMWVMPVAEYLGIKPKFVDS
TMIGGSSFVSHMLPAMMALEAGLCDAVLVCYGSNQRTSTVGRAGISKVRAVLDPQPYENPYQPLSPITSYALAAARHMHQ
YGTTREHLAEVAVAARKWAQLNPEAQMRDPLSIEDVLNARMVSDPLSVRDCCLVTDGAGAYVMVRADRAKDMAKPPVYVL
GNATATWHRQISCMPDVTVTAAKESGERAFAMAGLKPSDVDVAELYDAFTINTLLFLEDLGFCPKGEGGHFVSGGGIAPG
GRLPVNTNGGGLSCVHPGMYGMFITIEAVRQLRGECGDRQVKDAEVAVVHGNGGTLSSQATAILGTAATL
>Mature_389_residues
SLSSLRGSVAIVGVGQAGLGEAHGKTEMEILVEAAKAAVKDAGMSMRDIDGIATASVGATMWVMPVAEYLGIKPKFVDST
MIGGSSFVSHMLPAMMALEAGLCDAVLVCYGSNQRTSTVGRAGISKVRAVLDPQPYENPYQPLSPITSYALAAARHMHQY
GTTREHLAEVAVAARKWAQLNPEAQMRDPLSIEDVLNARMVSDPLSVRDCCLVTDGAGAYVMVRADRAKDMAKPPVYVLG
NATATWHRQISCMPDVTVTAAKESGERAFAMAGLKPSDVDVAELYDAFTINTLLFLEDLGFCPKGEGGHFVSGGGIAPGG
RLPVNTNGGGLSCVHPGMYGMFITIEAVRQLRGECGDRQVKDAEVAVVHGNGGTLSSQATAILGTAATL

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344767, Length=239, Percent_Identity=33.8912133891213, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI302344760, Length=239, Percent_Identity=33.8912133891213, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI19923233, Length=239, Percent_Identity=33.8912133891213, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI302344762, Length=239, Percent_Identity=33.8912133891213, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI55956775, Length=202, Percent_Identity=31.6831683168317, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17537653, Length=236, Percent_Identity=33.4745762711864, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI19921506, Length=232, Percent_Identity=33.6206896551724, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24585051, Length=232, Percent_Identity=33.1896551724138, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40904; Mature: 40773

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSLRGSVAIVGVGQAGLGEAHGKTEMEILVEAAKAAVKDAGMSMRDIDGIATASVGA
CCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCH
TMWVMPVAEYLGIKPKFVDSTMIGGSSFVSHMLPAMMALEAGLCDAVLVCYGSNQRTSTV
HHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
GRAGISKVRAVLDPQPYENPYQPLSPITSYALAAARHMHQYGTTREHLAEVAVAARKWAQ
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LNPEAQMRDPLSIEDVLNARMVSDPLSVRDCCLVTDGAGAYVMVRADRAKDMAKPPVYVL
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCEEEE
GNATATWHRQISCMPDVTVTAAKESGERAFAMAGLKPSDVDVAELYDAFTINTLLFLEDL
ECCCEEEHEEEECCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
GFCPKGEGGHFVSGGGIAPGGRLPVNTNGGGLSCVHPGMYGMFITIEAVRQLRGECGDRQ
CCCCCCCCCEEECCCCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCC
VKDAEVAVVHGNGGTLSSQATAILGTAATL
CCCCEEEEEECCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
SLSSLRGSVAIVGVGQAGLGEAHGKTEMEILVEAAKAAVKDAGMSMRDIDGIATASVGA
CCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCH
TMWVMPVAEYLGIKPKFVDSTMIGGSSFVSHMLPAMMALEAGLCDAVLVCYGSNQRTSTV
HHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
GRAGISKVRAVLDPQPYENPYQPLSPITSYALAAARHMHQYGTTREHLAEVAVAARKWAQ
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LNPEAQMRDPLSIEDVLNARMVSDPLSVRDCCLVTDGAGAYVMVRADRAKDMAKPPVYVL
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCEEEE
GNATATWHRQISCMPDVTVTAAKESGERAFAMAGLKPSDVDVAELYDAFTINTLLFLEDL
ECCCEEEHEEEECCCCCEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
GFCPKGEGGHFVSGGGIAPGGRLPVNTNGGGLSCVHPGMYGMFITIEAVRQLRGECGDRQ
CCCCCCCCCEEECCCCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCC
VKDAEVAVVHGNGGTLSSQATAILGTAATL
CCCCEEEEEECCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]