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The map label for this gene is mlaC [H]

Identifier: 73542802

GI number: 73542802

Start: 3424415

End: 3425044

Strand: Reverse

Name: mlaC [H]

Synonym: Reut_A3118

Alternate gene names: 73542802

Gene position: 3425044-3424415 (Counterclockwise)

Preceding gene: 73542803

Following gene: 73542801

Centisome position: 89.98

GC content: 63.02

Gene sequence:

>630_bases
ATGATCAAGCGACTGTTGCTCCCCCTCCTCGCTGTAGCTGCCTTTACCGGTGCCGCCCATGCGCAGGTTTCGGCGCAGGA
TGCCGCCAGCCCCGAAGCGCTGGTCAAGGCCGTGGTCAACGATGTGATGACCAGCGTCAAGAGCGACAAGGACATGCAGG
CCGGGAATATCGGCAAGATCTCCGCCCTGGTCGAGCAGAAGATCCTGCCGAACGCGAACTTCCAGAAGACGACGCAGATC
GCCATGGGCCGCAACTGGTCGAAGGCCACGCCCGAACAGCAGAAGGTCATCACCGACGAGTTCAAGACGCTGCTGATCCG
CACCTACGCGGGCGCGATCGCGCAGATTCGCGACCAGACCGTGCAGTACAAGCCGTACCGCGGTTCGCCGGACGACACCG
ATGCGACTATCCGCACCCAGGTGATCAACAAGGGCGAGCCGATCCAGCTCGACTACCGTCTCGAGAAGACGGCGCAGGGC
TGGAAGGTCTATGACATCAACGTGCTGGGCGCGTGGCTGACCGAGGCCTACAAGGGCAGCTTCAACACCATCGTCGGCCA
GCAGGGCGTGGACGGCGTGATCAAGACGCTGCAGGACCGCAACCGCCAGCTGGCCAACGCCAAGAGCTGA

Upstream 100 bases:

>100_bases
ACGGACTATGTTCCAATGTGCGCAACGCCTGGGGATTGCGGGCTTCGTAAAGCCGGACCTGCCCCGGGCGGCGAATGAAT
CTGACTGAGAAGGAAATTCC

Downstream 100 bases:

>100_bases
CGTCGCGCTGCCGCTGCCGCTGCCGCTGCCGCGCTGCATTGCAGCACGCAGCGGCAATCTGCTCTACAATCGCTGTACGC
ATGCAAGCTCCCGCCTTTGT

Product: toluene tolerance

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIKRLLLPLLAVAAFTGAAHAQVSAQDAASPEALVKAVVNDVMTSVKSDKDMQAGNIGKISALVEQKILPNANFQKTTQI
AMGRNWSKATPEQQKVITDEFKTLLIRTYAGAIAQIRDQTVQYKPYRGSPDDTDATIRTQVINKGEPIQLDYRLEKTAQG
WKVYDINVLGAWLTEAYKGSFNTIVGQQGVDGVIKTLQDRNRQLANAKS

Sequences:

>Translated_209_residues
MIKRLLLPLLAVAAFTGAAHAQVSAQDAASPEALVKAVVNDVMTSVKSDKDMQAGNIGKISALVEQKILPNANFQKTTQI
AMGRNWSKATPEQQKVITDEFKTLLIRTYAGAIAQIRDQTVQYKPYRGSPDDTDATIRTQVINKGEPIQLDYRLEKTAQG
WKVYDINVLGAWLTEAYKGSFNTIVGQQGVDGVIKTLQDRNRQLANAKS
>Mature_209_residues
MIKRLLLPLLAVAAFTGAAHAQVSAQDAASPEALVKAVVNDVMTSVKSDKDMQAGNIGKISALVEQKILPNANFQKTTQI
AMGRNWSKATPEQQKVITDEFKTLLIRTYAGAIAQIRDQTVQYKPYRGSPDDTDATIRTQVINKGEPIQLDYRLEKTAQG
WKVYDINVLGAWLTEAYKGSFNTIVGQQGVDGVIKTLQDRNRQLANAKS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=207, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 22932; Mature: 22932

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRLLLPLLAVAAFTGAAHAQVSAQDAASPEALVKAVVNDVMTSVKSDKDMQAGNIGKI
CHHHHHHHHHHHHHHCCCHHCEECCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
SALVEQKILPNANFQKTTQIAMGRNWSKATPEQQKVITDEFKTLLIRTYAGAIAQIRDQT
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQYKPYRGSPDDTDATIRTQVINKGEPIQLDYRLEKTAQGWKVYDINVLGAWLTEAYKGS
EEECCCCCCCCCCCHHHHHEECCCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHCCC
FNTIVGQQGVDGVIKTLQDRNRQLANAKS
HHHHHCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKRLLLPLLAVAAFTGAAHAQVSAQDAASPEALVKAVVNDVMTSVKSDKDMQAGNIGKI
CHHHHHHHHHHHHHHCCCHHCEECCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
SALVEQKILPNANFQKTTQIAMGRNWSKATPEQQKVITDEFKTLLIRTYAGAIAQIRDQT
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQYKPYRGSPDDTDATIRTQVINKGEPIQLDYRLEKTAQGWKVYDINVLGAWLTEAYKGS
EEECCCCCCCCCCCHHHHHEECCCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHCCC
FNTIVGQQGVDGVIKTLQDRNRQLANAKS
HHHHHCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]