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The map label for this gene is hitA [H]

Identifier: 73542785

GI number: 73542785

Start: 3411860

End: 3412216

Strand: Reverse

Name: hitA [H]

Synonym: Reut_A3101

Alternate gene names: 73542785

Gene position: 3412216-3411860 (Counterclockwise)

Preceding gene: 73542786

Following gene: 73542784

Centisome position: 89.64

GC content: 59.66

Gene sequence:

>357_bases
ATGAATTCCCAGGATAATTGCATCTTCTGCAAGATTGTGGCTGGCCAGATCCCGTCGCGGAAAGTCTATGAAGACGACGA
CATGATGGCTTTCCACGATATCCACCCGAAGGCCCCGGTACATTTCCTTCTGATCCCCAAGTCACATGTCGACTCGCTGG
CAGAGTGCGGTCCAGCCGAAGGGGAGGTGCTTGCTAGAATGATGCTGAAGGTGCCAGAACTGGCGCGCGCGGCAGGCTGT
GGCAACGGCTTCCGGACGGTGATCAATACCGGCCCGGATGGCGGCCAGGAGGTCTACCACTTGCACGTGCATGTGCTCGG
CGGGCCGCGCCACCAATGGAAGGTGCCGCTGCCCTGA

Upstream 100 bases:

>100_bases
GCTTTACCTCAACGACAGCAAGCCAATGTATCCGGAGCAGTCCTTCTAGCCGGGATATGGCGGCGCGCTGGTGTGCGCCC
GACATCGCAACGAAAACTTC

Downstream 100 bases:

>100_bases
ACAGGCAACCCTTGGCATGAGGAGCCGGACCGCGCGTGCGGTCCGGACGCTGCGCCGGCAACCGTCGCCCGGCGCGGCCA
AATTCGGACGGAACAACGGG

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MNSQDNCIFCKIVAGQIPSRKVYEDDDMMAFHDIHPKAPVHFLLIPKSHVDSLAECGPAEGEVLARMMLKVPELARAAGC
GNGFRTVINTGPDGGQEVYHLHVHVLGGPRHQWKVPLP

Sequences:

>Translated_118_residues
MNSQDNCIFCKIVAGQIPSRKVYEDDDMMAFHDIHPKAPVHFLLIPKSHVDSLAECGPAEGEVLARMMLKVPELARAAGC
GNGFRTVINTGPDGGQEVYHLHVHVLGGPRHQWKVPLP
>Mature_118_residues
MNSQDNCIFCKIVAGQIPSRKVYEDDDMMAFHDIHPKAPVHFLLIPKSHVDSLAECGPAEGEVLARMMLKVPELARAAGC
GNGFRTVINTGPDGGQEVYHLHVHVLGGPRHQWKVPLP

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=108, Percent_Identity=43.5185185185185, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI14211923, Length=107, Percent_Identity=42.0560747663551, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1787346, Length=105, Percent_Identity=40.9523809523809, Blast_Score=84, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17506713, Length=109, Percent_Identity=42.2018348623853, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574010, Length=111, Percent_Identity=41.4414414414414, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24581222, Length=111, Percent_Identity=41.4414414414414, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 12961; Mature: 12961

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQDNCIFCKIVAGQIPSRKVYEDDDMMAFHDIHPKAPVHFLLIPKSHVDSLAECGPAE
CCCCCCEEEEEEEECCCCCCCEECCCCEEEEECCCCCCCEEEEEECHHHHHHHHHCCCCC
GEVLARMMLKVPELARAAGCGNGFRTVINTGPDGGQEVYHLHVHVLGGPRHQWKVPLP
HHHHHHHHHHCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCEECCCC
>Mature Secondary Structure
MNSQDNCIFCKIVAGQIPSRKVYEDDDMMAFHDIHPKAPVHFLLIPKSHVDSLAECGPAE
CCCCCCEEEEEEEECCCCCCCEECCCCEEEEECCCCCCCEEEEEECHHHHHHHHHCCCCC
GEVLARMMLKVPELARAAGCGNGFRTVINTGPDGGQEVYHLHVHVLGGPRHQWKVPLP
HHHHHHHHHHCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA