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The map label for this gene is trxB [H]

Identifier: 73542286

GI number: 73542286

Start: 2853865

End: 2854830

Strand: Direct

Name: trxB [H]

Synonym: Reut_A2601

Alternate gene names: 73542286

Gene position: 2853865-2854830 (Clockwise)

Preceding gene: 73542281

Following gene: 73542287

Centisome position: 74.97

GC content: 65.32

Gene sequence:

>966_bases
ATGGCAAAACACGCAAAAGTGCTGATTCTCGGATCCGGTCCCGCCGGCTACACCGCCGCTGTCTACGCAGCCCGCGCCAA
CCTGGAACCGGTGCTGATCACCGGCCTGGCGCAAGGCGGCCAGCTGATGACCACCACGGATGTCGAGAACTGGCCGGGCG
ACGCCAAGGGCGTGCAGGGTCCGGAACTGATGCAGCGCCTGCTGGCCCATGCAGAAGAATTCAAGACGGAAATCATCTTC
GATCACATCCACACGGCCAAGCTCGTCGATGAAAGCGGCAATCCGGCCCGCCCGTTCCGGCTGATCGGCGATGCCGGCGA
GTACACCTGTGATGCCCTGATCATCGCCACCGGCGCGTCGGCGCAGTACCTGGGCCTGCCGTCCGAAGAATCGTTCATGG
GCCGCGGCGTGTCGGCCTGCGCCACCTGCGACGGCTTCTTCTACAAGAACCAGGAAGTCGCCGTGGTCGGCGGCGGCAAT
ACCGCTGTGGAAGAAGCACTGTACCTGTCCCATATCGCCAGCAAGGTCACCGTGATCCACCGCCGGGACAGCTTCCGCGC
CGAGCCGATCCTGGTCGACCGCCTGCTGCAGCGCGAGAAGGAAGGCCGTGTCGAGATCCGTTACGACAGCGTGCTCGACG
AAGTGCTTGGCGACGACTCCGGCGTGACCGGCCTGCGCATCCGCGGTGCGAAGTCGGGCGAGACCCAGGACCTCAAGCTG
GCCGGCGTGTTCATCGCGATCGGCCACAAGCCCAATACCGACCTGTTTGTCGGCCAGCTCGCCATGGAAAATGGCTACCT
GGTGACGAAGTCGGGCCTGTCCGGCGACGCCACCGCTACCAGCGTCCCGGGCGTGTTCGCCGCCGGCGACGTGCAGGACC
ACGTCTACCGCCAGGCCATCACCAGCGCCGGCACAGGCTGCATGGCCGCACTGGACGCCCAGCGCTACATTGAAGCGCTG
AAGTAA

Upstream 100 bases:

>100_bases
CCATTGGAATTTGCAACAGTGGGCAAATCGCGCTCCTCTTATAATGTCGGTTTCGAGCAATGCCGGTGCGCAGCAAGACG
CACCGCCACAGGAACGCATC

Downstream 100 bases:

>100_bases
GCCCTCCGCGGCCCGGCCGACCGGCCGGGCCCGCCCCTCCCGATATAATTGGCGCCGAGCCCCCGGAGAATTTTCCATGA
CGCACGGCGCCAAACCCGAC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAKHAKVLILGSGPAGYTAAVYAARANLEPVLITGLAQGGQLMTTTDVENWPGDAKGVQGPELMQRLLAHAEEFKTEIIF
DHIHTAKLVDESGNPARPFRLIGDAGEYTCDALIIATGASAQYLGLPSEESFMGRGVSACATCDGFFYKNQEVAVVGGGN
TAVEEALYLSHIASKVTVIHRRDSFRAEPILVDRLLQREKEGRVEIRYDSVLDEVLGDDSGVTGLRIRGAKSGETQDLKL
AGVFIAIGHKPNTDLFVGQLAMENGYLVTKSGLSGDATATSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRYIEAL
K

Sequences:

>Translated_321_residues
MAKHAKVLILGSGPAGYTAAVYAARANLEPVLITGLAQGGQLMTTTDVENWPGDAKGVQGPELMQRLLAHAEEFKTEIIF
DHIHTAKLVDESGNPARPFRLIGDAGEYTCDALIIATGASAQYLGLPSEESFMGRGVSACATCDGFFYKNQEVAVVGGGN
TAVEEALYLSHIASKVTVIHRRDSFRAEPILVDRLLQREKEGRVEIRYDSVLDEVLGDDSGVTGLRIRGAKSGETQDLKL
AGVFIAIGHKPNTDLFVGQLAMENGYLVTKSGLSGDATATSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRYIEAL
K
>Mature_320_residues
AKHAKVLILGSGPAGYTAAVYAARANLEPVLITGLAQGGQLMTTTDVENWPGDAKGVQGPELMQRLLAHAEEFKTEIIFD
HIHTAKLVDESGNPARPFRLIGDAGEYTCDALIIATGASAQYLGLPSEESFMGRGVSACATCDGFFYKNQEVAVVGGGNT
AVEEALYLSHIASKVTVIHRRDSFRAEPILVDRLLQREKEGRVEIRYDSVLDEVLGDDSGVTGLRIRGAKSGETQDLKLA
GVFIAIGHKPNTDLFVGQLAMENGYLVTKSGLSGDATATSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRYIEALK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=67.0846394984326, Blast_Score=450, Evalue=1e-128,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=34.2948717948718, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=330, Percent_Identity=46.3636363636364, Blast_Score=279, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6321898, Length=328, Percent_Identity=47.2560975609756, Blast_Score=276, Evalue=4e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34085; Mature: 33954

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHAKVLILGSGPAGYTAAVYAARANLEPVLITGLAQGGQLMTTTDVENWPGDAKGVQG
CCCCEEEEEEECCCCCCCEEEEEHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCC
PELMQRLLAHAEEFKTEIIFDHIHTAKLVDESGNPARPFRLIGDAGEYTCDALIIATGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCEEEEEEEEECCC
AQYLGLPSEESFMGRGVSACATCDGFFYKNQEVAVVGGGNTAVEEALYLSHIASKVTVIH
CEEECCCCCHHHHCCCCHHHEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEE
RRDSFRAEPILVDRLLQREKEGRVEIRYDSVLDEVLGDDSGVTGLRIRGAKSGETQDLKL
ECCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEE
AGVFIAIGHKPNTDLFVGQLAMENGYLVTKSGLSGDATATSVPGVFAAGDVQDHVYRQAI
EEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHH
TSAGTGCMAALDAQRYIEALK
HHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKHAKVLILGSGPAGYTAAVYAARANLEPVLITGLAQGGQLMTTTDVENWPGDAKGVQG
CCCEEEEEEECCCCCCCEEEEEHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCC
PELMQRLLAHAEEFKTEIIFDHIHTAKLVDESGNPARPFRLIGDAGEYTCDALIIATGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCEEEEEEEEECCC
AQYLGLPSEESFMGRGVSACATCDGFFYKNQEVAVVGGGNTAVEEALYLSHIASKVTVIH
CEEECCCCCHHHHCCCCHHHEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEE
RRDSFRAEPILVDRLLQREKEGRVEIRYDSVLDEVLGDDSGVTGLRIRGAKSGETQDLKL
ECCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEE
AGVFIAIGHKPNTDLFVGQLAMENGYLVTKSGLSGDATATSVPGVFAAGDVQDHVYRQAI
EEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHH
TSAGTGCMAALDAQRYIEALK
HHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]