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The map label for this gene is ubiG

Identifier: 73542265

GI number: 73542265

Start: 2827041

End: 2827790

Strand: Direct

Name: ubiG

Synonym: Reut_A2580

Alternate gene names: 73542265

Gene position: 2827041-2827790 (Clockwise)

Preceding gene: 73542264

Following gene: 73542266

Centisome position: 74.27

GC content: 60.67

Gene sequence:

>750_bases
ATGACGTCGCCTTCGCAAGTCCTGCCGGCCTCCGCTGGCAAACCCACCGGCCCCAATGCCGACCCCAAGGAAATCGACAA
GTTCAGCGAACTGGCCCACCACTGGTGGGACCCGAACAGCGAGTTCAAGCCGCTGCACGACCTGAATCCGCTGCGGCTCG
GTTGGATTGACGGCATTGCCGGACTGGCCGGTAAGAAAGTTGTGGATATCGGCTGCGGTGGCGGCATCCTGTCCGAGAGT
ATGGCGCGCCTTGGCGCAAATGTGCGTGGAATTGACCTCTCGACGAAGGCGCTTCGGGTGGCCGACCTGCACAGCCTCGA
GTCCGGCGTTGCCGTCAACTACGAGGAGATCGCCGCGGAAGCGCTGGCGGCGCGCGAACCGGGCAGCGTGGATGTCGTAA
CTTGCATGGAAATGCTTGAACATGTGCCCGATCCCGAGTCGATCGTCCAGGCGTGCGCGACGCTAGTCCGCCCGGGCGGC
CATGTCTTCGTCTCGACGATCAACCGCAACCTTAAGGCGTATCTGATGGCCGTCGTGGGCGCCGAGTACATCCTTCAAAT
GCTGCCGCGTGGCACGCACGACTACGAGAAATTCATCACGCCATCGGAAATGGCGCGATTTGCCCGCAATGCCGGACTAG
ATCTCGTGGAAATGCGCGGCATGACCTATAACCCGCTGTCGCAGATTTATTCACTGAGCCGTGATACGGACGTCAATTAC
ATGATGGCGTTTCGCCGGGTTGCAGAATGA

Upstream 100 bases:

>100_bases
AGGAAAGCCCAGCGCAAGCTGGGCTTTTTTTTTGGTACAGTGGCCAGACACCCTCCTATCTGCCGGCTCAGGCACTTCGT
CCGTACCGGCACTGCAAACC

Downstream 100 bases:

>100_bases
TGACTGGAATCGACGCCGTGTTTTTCGATCTCGACGGGACGCTCGCCGACACCGCTCCGGATCTTGCCGCAGCTGCCAAC
CGGCTGGTCGTCGAGCATGG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTSPSQVLPASAGKPTGPNADPKEIDKFSELAHHWWDPNSEFKPLHDLNPLRLGWIDGIAGLAGKKVVDIGCGGGILSES
MARLGANVRGIDLSTKALRVADLHSLESGVAVNYEEIAAEALAAREPGSVDVVTCMEMLEHVPDPESIVQACATLVRPGG
HVFVSTINRNLKAYLMAVVGAEYILQMLPRGTHDYEKFITPSEMARFARNAGLDLVEMRGMTYNPLSQIYSLSRDTDVNY
MMAFRRVAE

Sequences:

>Translated_249_residues
MTSPSQVLPASAGKPTGPNADPKEIDKFSELAHHWWDPNSEFKPLHDLNPLRLGWIDGIAGLAGKKVVDIGCGGGILSES
MARLGANVRGIDLSTKALRVADLHSLESGVAVNYEEIAAEALAAREPGSVDVVTCMEMLEHVPDPESIVQACATLVRPGG
HVFVSTINRNLKAYLMAVVGAEYILQMLPRGTHDYEKFITPSEMARFARNAGLDLVEMRGMTYNPLSQIYSLSRDTDVNY
MMAFRRVAE
>Mature_248_residues
TSPSQVLPASAGKPTGPNADPKEIDKFSELAHHWWDPNSEFKPLHDLNPLRLGWIDGIAGLAGKKVVDIGCGGGILSESM
ARLGANVRGIDLSTKALRVADLHSLESGVAVNYEEIAAEALAAREPGSVDVVTCMEMLEHVPDPESIVQACATLVRPGGH
VFVSTINRNLKAYLMAVVGAEYILQMLPRGTHDYEKFITPSEMARFARNAGLDLVEMRGMTYNPLSQIYSLSRDTDVNYM
MAFRRVAE

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=236, Percent_Identity=34.7457627118644, Blast_Score=165, Evalue=3e-41,
Organism=Escherichia coli, GI1788564, Length=229, Percent_Identity=56.3318777292576, Blast_Score=272, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI115533050, Length=234, Percent_Identity=34.1880341880342, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=300, Percent_Identity=31, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281365311, Length=248, Percent_Identity=32.258064516129, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24585589, Length=269, Percent_Identity=30.4832713754647, Blast_Score=131, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_CUPPJ (Q46Y42)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_296785.1
- ProteinModelPortal:   Q46Y42
- SMR:   Q46Y42
- GeneID:   3609604
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2580
- NMPDR:   fig|264198.3.peg.3334
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- BioCyc:   REUT264198:REUT_A2580-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 27108; Mature: 26977

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSQVLPASAGKPTGPNADPKEIDKFSELAHHWWDPNSEFKPLHDLNPLRLGWIDGIA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHH
GLAGKKVVDIGCGGGILSESMARLGANVRGIDLSTKALRVADLHSLESGVAVNYEEIAAE
HHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
ALAAREPGSVDVVTCMEMLEHVPDPESIVQACATLVRPGGHVFVSTINRNLKAYLMAVVG
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
AEYILQMLPRGTHDYEKFITPSEMARFARNAGLDLVEMRGMTYNPLSQIYSLSRDTDVNY
HHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCEEHHCCCCCCHHHHHHHHCCCCCHHH
MMAFRRVAE
HHHHHHHCC
>Mature Secondary Structure 
TSPSQVLPASAGKPTGPNADPKEIDKFSELAHHWWDPNSEFKPLHDLNPLRLGWIDGIA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHH
GLAGKKVVDIGCGGGILSESMARLGANVRGIDLSTKALRVADLHSLESGVAVNYEEIAAE
HHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
ALAAREPGSVDVVTCMEMLEHVPDPESIVQACATLVRPGGHVFVSTINRNLKAYLMAVVG
HHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
AEYILQMLPRGTHDYEKFITPSEMARFARNAGLDLVEMRGMTYNPLSQIYSLSRDTDVNY
HHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCEEHHCCCCCCHHHHHHHHCCCCCHHH
MMAFRRVAE
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA