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The map label for this gene is moaE [H]

Identifier: 73541677

GI number: 73541677

Start: 2179936

End: 2180436

Strand: Reverse

Name: moaE [H]

Synonym: Reut_A1989

Alternate gene names: 73541677

Gene position: 2180436-2179936 (Counterclockwise)

Preceding gene: 73541678

Following gene: 73541676

Centisome position: 57.28

GC content: 67.27

Gene sequence:

>501_bases
ATGAGCGTCAGGGTACAGAGGGAGGATTTCGACCTCGGCGCCGAAGTCGCGGCGCTACGGAGCGGCCGTCCGGCCGTGGG
CGCGGTGGCAAGCTTCATCGGCACGGTACGCGATATCAGCGAGGGTAGCGCCGTCAGCGCGATGGAGCTCGAGCACTATC
CCGGCATGACCGAGAAGGCGCTCGCCCGCATCGAAGCCGCTGCCTGCGCGCGCTGGGAGCTACTGGGCGTGACGATTATC
CACCGCGTCGGGCCGCTGCTGCCGCTGGACCAGATCGTACTGGTGGCGGTCGCCTCCGCGCATCGCGGCAATGCGTTTGC
GGCGTGCGAATTCATCATGGACTACCTCAAGTCCGAAGCGCCGTTCTGGAAGAAGGAAGAGACGCCGGAAGGTGCGCGCT
GGGTCGACGCCCGCGTGACCGACGAGGCGGCCCTGAAGCGTTGGGGGATTCCGTCCTTCAACGCGAGCGGCACTGAAGCC
GACAGCGACGGCGAGGCCTGA

Upstream 100 bases:

>100_bases
GCGCTGCGCATGGCCGTTGACCACGCCGTGGCACGCGCTGATACGGCGATCACCGAAGGCTGCGAGGTGGCCTTCTTCCC
ACCGGTCACCGGAGGCTGAC

Downstream 100 bases:

>100_bases
TGGGGCCGCTCGGATTCGTTGCGGTCGGCATCGGCGCTGCGGTCGGCGCGTGGCTGCGCTGGGGGTTATCGGTCATGTGG
AACGCCCTGAACCCGGCCTT

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSVRVQREDFDLGAEVAALRSGRPAVGAVASFIGTVRDISEGSAVSAMELEHYPGMTEKALARIEAAACARWELLGVTII
HRVGPLLPLDQIVLVAVASAHRGNAFAACEFIMDYLKSEAPFWKKEETPEGARWVDARVTDEAALKRWGIPSFNASGTEA
DSDGEA

Sequences:

>Translated_166_residues
MSVRVQREDFDLGAEVAALRSGRPAVGAVASFIGTVRDISEGSAVSAMELEHYPGMTEKALARIEAAACARWELLGVTII
HRVGPLLPLDQIVLVAVASAHRGNAFAACEFIMDYLKSEAPFWKKEETPEGARWVDARVTDEAALKRWGIPSFNASGTEA
DSDGEA
>Mature_165_residues
SVRVQREDFDLGAEVAALRSGRPAVGAVASFIGTVRDISEGSAVSAMELEHYPGMTEKALARIEAAACARWELLGVTIIH
RVGPLLPLDQIVLVAVASAHRGNAFAACEFIMDYLKSEAPFWKKEETPEGARWVDARVTDEAALKRWGIPSFNASGTEAD
SDGEA

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=112, Percent_Identity=34.8214285714286, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1787003, Length=141, Percent_Identity=56.7375886524823, Blast_Score=157, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21356259, Length=102, Percent_Identity=34.3137254901961, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17843; Mature: 17712

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVQREDFDLGAEVAALRSGRPAVGAVASFIGTVRDISEGSAVSAMELEHYPGMTEKA
CCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHH
LARIEAAACARWELLGVTIIHRVGPLLPLDQIVLVAVASAHRGNAFAACEFIMDYLKSEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PFWKKEETPEGARWVDARVTDEAALKRWGIPSFNASGTEADSDGEA
CCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVRVQREDFDLGAEVAALRSGRPAVGAVASFIGTVRDISEGSAVSAMELEHYPGMTEKA
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHH
LARIEAAACARWELLGVTIIHRVGPLLPLDQIVLVAVASAHRGNAFAACEFIMDYLKSEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PFWKKEETPEGARWVDARVTDEAALKRWGIPSFNASGTEADSDGEA
CCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]