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The map label for this gene is cbl [H]

Identifier: 73541655

GI number: 73541655

Start: 2153666

End: 2154613

Strand: Reverse

Name: cbl [H]

Synonym: Reut_A1967

Alternate gene names: 73541655

Gene position: 2154613-2153666 (Counterclockwise)

Preceding gene: 73541656

Following gene: 73541654

Centisome position: 56.6

GC content: 66.67

Gene sequence:

>948_bases
ATGAATTTTCAGCAACTCCGATCGATCCGCGAGGCGGTACGCCGCCAGTTCAACCTGACCGAAGTCGCCAACGCGCTGTA
CACCTCGCAGCCGGGCGTGTCGCGCCAGATCCGCGAACTCGAAGAAGAACTCGGCGTGGAGATTTTCGAGCGCTATGGCA
AGCGCCTGACCGGGCTGACCGAGCCGGGCCGCGAGATCGTGCGCATTGTCGAGCGCCTGCTGCTCGAGGCCGAGAACCTG
CGCCAGGCCGGGGACGAATTTGCGGGCCGCCATACCGGCCGCCTGACGGTGGCCACGACGCACACGCAGGCACGCTATGC
GTTGCCGAAGGTGGTGCAGTCGTTCCGTCGCGAGTATCCGCACGTCACGCTCGCGCTGCAGGAGGCGTCGCCCACGCACA
TCGTCGAACTGCTGCTGACGGGGCAGGCCGACATCGGCATCGCAACCGAGGCGCTTGCCACCGAGGCCGGGCTGACCTCG
TTTGACGCCTACACATGGCAGCACGTGCTGGTGGTCTCGCCCGATCATCCCCTGACGCTCGTGCCGGAGCCGACGCTGGA
AGACCTGGCCGGTTTCCCGCTGATCACGTATGACGCCGGCTTCACGGGCCGCCGCAAGATCGACGGCGCCTTCGCCGAGG
CCGGCCTGCAGCCCGAAATCGTGCTGACGGCGCTGGATGCGGACGTCATCAAGACCTATGCGGAGCTCGAACTGGGCGTG
GGCATCATCGCTTCGATGGCCTACGACGAGCGCAAGGACTCGGGCCTGGTGCGGATTTCGGCCGACCATCTGTTCGATTC
GAACACCACAAGCGTGGCGCTGCGGCGCGGCGCGTACCTGCGCGACTACGCCCACGCCTTCATCAACATGTTCGCGCCGC
ACCTGTCACGCGACACGGTCTCCAGCGCGCTGGGCGAAAGCGACACGCGGCAGGCCTTGGCCGCGTGA

Upstream 100 bases:

>100_bases
CGGTGCGTCCGCGCCAGCTGCGTGTCTTCACCCAGCACACACAACAACAATCGAACGCGCGCGCCAACGGCGCGACGTCA
AGCCGGCAAGGGGCAGTGCG

Downstream 100 bases:

>100_bases
TTGCGCGCTGGCTACCCGGCCGGCCTTGCATTGCTGCCACGTCCTGGCTGCCCCCATCTGTGCAGGCAGCGGCGCATGCC
GCTGTCCATCCCGTCCCCGC

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNFQQLRSIREAVRRQFNLTEVANALYTSQPGVSRQIRELEEELGVEIFERYGKRLTGLTEPGREIVRIVERLLLEAENL
RQAGDEFAGRHTGRLTVATTHTQARYALPKVVQSFRREYPHVTLALQEASPTHIVELLLTGQADIGIATEALATEAGLTS
FDAYTWQHVLVVSPDHPLTLVPEPTLEDLAGFPLITYDAGFTGRRKIDGAFAEAGLQPEIVLTALDADVIKTYAELELGV
GIIASMAYDERKDSGLVRISADHLFDSNTTSVALRRGAYLRDYAHAFINMFAPHLSRDTVSSALGESDTRQALAA

Sequences:

>Translated_315_residues
MNFQQLRSIREAVRRQFNLTEVANALYTSQPGVSRQIRELEEELGVEIFERYGKRLTGLTEPGREIVRIVERLLLEAENL
RQAGDEFAGRHTGRLTVATTHTQARYALPKVVQSFRREYPHVTLALQEASPTHIVELLLTGQADIGIATEALATEAGLTS
FDAYTWQHVLVVSPDHPLTLVPEPTLEDLAGFPLITYDAGFTGRRKIDGAFAEAGLQPEIVLTALDADVIKTYAELELGV
GIIASMAYDERKDSGLVRISADHLFDSNTTSVALRRGAYLRDYAHAFINMFAPHLSRDTVSSALGESDTRQALAA
>Mature_315_residues
MNFQQLRSIREAVRRQFNLTEVANALYTSQPGVSRQIRELEEELGVEIFERYGKRLTGLTEPGREIVRIVERLLLEAENL
RQAGDEFAGRHTGRLTVATTHTQARYALPKVVQSFRREYPHVTLALQEASPTHIVELLLTGQADIGIATEALATEAGLTS
FDAYTWQHVLVVSPDHPLTLVPEPTLEDLAGFPLITYDAGFTGRRKIDGAFAEAGLQPEIVLTALDADVIKTYAELELGV
GIIASMAYDERKDSGLVRISADHLFDSNTTSVALRRGAYLRDYAHAFINMFAPHLSRDTVSSALGESDTRQALAA

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=307, Percent_Identity=51.1400651465798, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1787530, Length=305, Percent_Identity=49.1803278688525, Blast_Score=304, Evalue=5e-84,
Organism=Escherichia coli, GI157672245, Length=283, Percent_Identity=31.8021201413428, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789204, Length=249, Percent_Identity=26.9076305220884, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790399, Length=282, Percent_Identity=24.822695035461, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788887, Length=290, Percent_Identity=27.2413793103448, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=24.2105263157895, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790208, Length=230, Percent_Identity=28.695652173913, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI2367136, Length=257, Percent_Identity=24.124513618677, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082132, Length=269, Percent_Identity=24.1635687732342, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=236, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081904, Length=222, Percent_Identity=29.2792792792793, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34818; Mature: 34818

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRSIREAVRRQFNLTEVANALYTSQPGVSRQIRELEEELGVEIFERYGKRLTGLT
CCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCC
EPGREIVRIVERLLLEAENLRQAGDEFAGRHTGRLTVATTHTQARYALPKVVQSFRREYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
HVTLALQEASPTHIVELLLTGQADIGIATEALATEAGLTSFDAYTWQHVLVVSPDHPLTL
CEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEE
VPEPTLEDLAGFPLITYDAGFTGRRKIDGAFAEAGLQPEIVLTALDADVIKTYAELELGV
CCCCCHHHHCCCCEEEECCCCCCCHHHCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
GIIASMAYDERKDSGLVRISADHLFDSNTTSVALRRGAYLRDYAHAFINMFAPHLSRDTV
HHHHHHHHHCCCCCCEEEEEHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHH
SSALGESDTRQALAA
HHHHCCCHHHHHHCC
>Mature Secondary Structure
MNFQQLRSIREAVRRQFNLTEVANALYTSQPGVSRQIRELEEELGVEIFERYGKRLTGLT
CCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCC
EPGREIVRIVERLLLEAENLRQAGDEFAGRHTGRLTVATTHTQARYALPKVVQSFRREYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
HVTLALQEASPTHIVELLLTGQADIGIATEALATEAGLTSFDAYTWQHVLVVSPDHPLTL
CEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEE
VPEPTLEDLAGFPLITYDAGFTGRRKIDGAFAEAGLQPEIVLTALDADVIKTYAELELGV
CCCCCHHHHCCCCEEEECCCCCCCHHHCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
GIIASMAYDERKDSGLVRISADHLFDSNTTSVALRRGAYLRDYAHAFINMFAPHLSRDTV
HHHHHHHHHCCCCCCEEEEEHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHH
SSALGESDTRQALAA
HHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]