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The map label for this gene is cheA [H]

Identifier: 73541646

GI number: 73541646

Start: 2143096

End: 2145480

Strand: Reverse

Name: cheA [H]

Synonym: Reut_A1958

Alternate gene names: 73541646

Gene position: 2145480-2143096 (Counterclockwise)

Preceding gene: 73541648

Following gene: 73541645

Centisome position: 56.36

GC content: 63.61

Gene sequence:

>2385_bases
ATGAGTATTCGTCATCGCATTACGCTGTTGATCATGCTGGCGTTCCTGTCGCTGGCCGGTATTGGCGGCTACGCCGTCTA
TCAGACGCGGGGCAGCGCCGCACAGGTCAAGGAAGTGACGGAAGGCGTCGTGCCGAGCGCGCTGGCGTCTGCCGATGTCG
TCGCACTCGTCAAGGATGTGCAGCTTGCGACGATGGCGCTCGTGTATGCGCCCGACGCCGCGCTGGTGGCGCAAAGCCAG
GCCGAACTGAAGGACCATCAGGCGGCGTTAAGCATGGCGCTCGCATCCCAGGCGGAGCACGCCCATACGCAGGCTCAGCG
CGGACTGGTGGAGCAGGCCAGGGAAAGCTTCGGCAATTACGCCGAGGCCATCCGCGAGACCGCGGAAATGAAAGCCGCTG
GCCGCGATGAACTCGCGCAGGCCTTTCTGTTTGCCAACGTGGCGCGCTATCGCGACGAAATGGAAAAGATCGTCCAGACG
CTTCGCGTGGAAAAAAACCGCGAGAAAGACGAGGCCATCACCGCACTGAACGGGCTGATGAGTACGACTACCACGGCGAT
CGGCGTGGTGAGCGGCATCGCAGTGCTGCTACTGGTTGGTGTCGGCATGGTGCTGTATCGCCAGATCGCTCGCCCGCTGA
CGCGCATGCAGGCAATGATGAGCGAGATTGCGGACAGCCAGGATTTTTCGCGGCGCGTACCGGTCGGCAGCGCGGACGAA
ATCGGCCGTTCGATCATCGCGTTCAACAGCATGATCGAGAGGATCCAGGAGAACGCGGGCCTGCTGCGCCAGAAGACTAC
CGACATGCAGGCTATCCTGCAGAACATGCAGCAGGGCATCCTGACCGTGGTGCCGGGCGCCGTTGTTCATCCCGAGTACT
CGAAGTTTCTCGAACAGATTCTGGAAACGCACGAGATCGAGGGCCGCCATGTCATGGAGCTGATCTTTGCGCACAGCGAT
ATCAGCGCCGAGCTGGCGTCGCAGGTGGATGCTGCGATTGACGCCTGTCTAGGGCAGGACCTGATGAACTTCGACTTCAA
CGAGCATCTGCTCGTGAAGGAAGTCACGCGCCGCATGCCGGACGGGAGCGTGAAAGTGCTGGACCTGAGCTGGTCGCCGA
TCACCGACGAGCACGACAACATCGTGCGGCTGATGCTGTGCCTGCGCGATGTCACGCAACTGCGCAAGCTTGCCGCCGAA
GCGAGCGAACAGAAGCAGGATCTCGAGATCATCGGCGAAATCCTCGCGGTGAACGAGGCATCGTTCAGCCGCTTCATGGA
AAGCGCGGTCGGGTTTGCGCGCGAGAACGAGCGCATCCTGCGCCAGAACGTGCAGGCGGACATCGACGCGGTCAACGCGT
TGTTCCGCAATATGCATACCGTGAAGGGCAATGCGCGCACGCACCAGTTCCGCCATATTGCCGAAGTCGCGCACGAGATC
GAACAGTCTTACGACTCGCTGCGCAGCGCCGCCGCCCAGGGCAACTGGGACAAGGACCGCCTGCTCGACGAACTTGAGCG
CGTGCATGACGCGCTGGGCCGTTATGCAATGATCAGCGAATCGCGGCTCGGGCGCAGCATGCAGGGCGGTGGTTCGGCGG
TGGGCATGCCGTCTGCCGATGAAGAAGCCATCCGCGCGACGCTGGCGCTCGTGGAGCAATCTGATCCGACCAGCCTGCGC
GAACTGGCTGCCATGCGTGATGCCGTGCACCGCAACCTGAGCTGCCTTGGGACAGTCAGCGTCGATCATGCGCTGTCGGG
CGTGATCGACTCCCTGCCGTCGCTGGCCACGGAACTCGGCAAGGCCGCGCCGGCTGTACAGGTCAATGGTGGCGGCCAAC
GCGTAGTGGCGAAGGCCGGCGCCGTGCTCACGGATGTCTTTACCCACCTGTTTCGCAATGCGCTCGACCACGGCATCGAG
CAGCCCGACGTGCGCCGGCTGGAGGGCAAGCCGGCTGCAGGCCGGATCACGGTCGATGTGATCACGGACGAACAGGGCCT
GCGGGTAACGCTAGCCGATGACGGTCGCGGGCTCAGCCTTGGGCGCATCCGCAGCATTGCCATCGCGCGCGGTTGGTTGC
AAGCCAATCAGGCGTGCAGCGATGCGGAGCTTGCGCAGTTCATCTTCCGCGCCGGGTTTTCCACGGCGCAGAACGTGACG
GCTGTTTCGGGTCGCGGTGTCGGCATGGAGGCGGTGCTGGCCTTCCTGCAGCGCGAGGGCGGCAACGTGAGCCTGCACTT
TACCGACGACAGCGAAGGCGCGACGTTCAGGCCCTTCGAAACCATCGTGCGGCTGCCGCAACGCTACATCGTGGACGCCG
CCGGACTTGAGGGCCGGCACCCGCAAGCGGACCGCGCAGCCGTACCGCAGCCGATGGAAGCGTAA

Upstream 100 bases:

>100_bases
TTTGTCACAATAATTTGGCCCTGTTTTCCACCTCTCTTCTGACTTGCGCAATGGCGCAGGATCAGTTCGCAAACACAGCA
TTGGGGCATTGCAGGTAGCT

Downstream 100 bases:

>100_bases
ACGATCTACGTATCAGTATCAGTGCAATGAGCAGACAGACTTTGACAGAGGGATCCGCCGGCCGTGCCGGCACGTGGGCC
GCGCGATGCAAGACATGGTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 793

Protein sequence:

>794_residues
MSIRHRITLLIMLAFLSLAGIGGYAVYQTRGSAAQVKEVTEGVVPSALASADVVALVKDVQLATMALVYAPDAALVAQSQ
AELKDHQAALSMALASQAEHAHTQAQRGLVEQARESFGNYAEAIRETAEMKAAGRDELAQAFLFANVARYRDEMEKIVQT
LRVEKNREKDEAITALNGLMSTTTTAIGVVSGIAVLLLVGVGMVLYRQIARPLTRMQAMMSEIADSQDFSRRVPVGSADE
IGRSIIAFNSMIERIQENAGLLRQKTTDMQAILQNMQQGILTVVPGAVVHPEYSKFLEQILETHEIEGRHVMELIFAHSD
ISAELASQVDAAIDACLGQDLMNFDFNEHLLVKEVTRRMPDGSVKVLDLSWSPITDEHDNIVRLMLCLRDVTQLRKLAAE
ASEQKQDLEIIGEILAVNEASFSRFMESAVGFARENERILRQNVQADIDAVNALFRNMHTVKGNARTHQFRHIAEVAHEI
EQSYDSLRSAAAQGNWDKDRLLDELERVHDALGRYAMISESRLGRSMQGGGSAVGMPSADEEAIRATLALVEQSDPTSLR
ELAAMRDAVHRNLSCLGTVSVDHALSGVIDSLPSLATELGKAAPAVQVNGGGQRVVAKAGAVLTDVFTHLFRNALDHGIE
QPDVRRLEGKPAAGRITVDVITDEQGLRVTLADDGRGLSLGRIRSIAIARGWLQANQACSDAELAQFIFRAGFSTAQNVT
AVSGRGVGMEAVLAFLQREGGNVSLHFTDDSEGATFRPFETIVRLPQRYIVDAAGLEGRHPQADRAAVPQPMEA

Sequences:

>Translated_794_residues
MSIRHRITLLIMLAFLSLAGIGGYAVYQTRGSAAQVKEVTEGVVPSALASADVVALVKDVQLATMALVYAPDAALVAQSQ
AELKDHQAALSMALASQAEHAHTQAQRGLVEQARESFGNYAEAIRETAEMKAAGRDELAQAFLFANVARYRDEMEKIVQT
LRVEKNREKDEAITALNGLMSTTTTAIGVVSGIAVLLLVGVGMVLYRQIARPLTRMQAMMSEIADSQDFSRRVPVGSADE
IGRSIIAFNSMIERIQENAGLLRQKTTDMQAILQNMQQGILTVVPGAVVHPEYSKFLEQILETHEIEGRHVMELIFAHSD
ISAELASQVDAAIDACLGQDLMNFDFNEHLLVKEVTRRMPDGSVKVLDLSWSPITDEHDNIVRLMLCLRDVTQLRKLAAE
ASEQKQDLEIIGEILAVNEASFSRFMESAVGFARENERILRQNVQADIDAVNALFRNMHTVKGNARTHQFRHIAEVAHEI
EQSYDSLRSAAAQGNWDKDRLLDELERVHDALGRYAMISESRLGRSMQGGGSAVGMPSADEEAIRATLALVEQSDPTSLR
ELAAMRDAVHRNLSCLGTVSVDHALSGVIDSLPSLATELGKAAPAVQVNGGGQRVVAKAGAVLTDVFTHLFRNALDHGIE
QPDVRRLEGKPAAGRITVDVITDEQGLRVTLADDGRGLSLGRIRSIAIARGWLQANQACSDAELAQFIFRAGFSTAQNVT
AVSGRGVGMEAVLAFLQREGGNVSLHFTDDSEGATFRPFETIVRLPQRYIVDAAGLEGRHPQADRAAVPQPMEA
>Mature_793_residues
SIRHRITLLIMLAFLSLAGIGGYAVYQTRGSAAQVKEVTEGVVPSALASADVVALVKDVQLATMALVYAPDAALVAQSQA
ELKDHQAALSMALASQAEHAHTQAQRGLVEQARESFGNYAEAIRETAEMKAAGRDELAQAFLFANVARYRDEMEKIVQTL
RVEKNREKDEAITALNGLMSTTTTAIGVVSGIAVLLLVGVGMVLYRQIARPLTRMQAMMSEIADSQDFSRRVPVGSADEI
GRSIIAFNSMIERIQENAGLLRQKTTDMQAILQNMQQGILTVVPGAVVHPEYSKFLEQILETHEIEGRHVMELIFAHSDI
SAELASQVDAAIDACLGQDLMNFDFNEHLLVKEVTRRMPDGSVKVLDLSWSPITDEHDNIVRLMLCLRDVTQLRKLAAEA
SEQKQDLEIIGEILAVNEASFSRFMESAVGFARENERILRQNVQADIDAVNALFRNMHTVKGNARTHQFRHIAEVAHEIE
QSYDSLRSAAAQGNWDKDRLLDELERVHDALGRYAMISESRLGRSMQGGGSAVGMPSADEEAIRATLALVEQSDPTSLRE
LAAMRDAVHRNLSCLGTVSVDHALSGVIDSLPSLATELGKAAPAVQVNGGGQRVVAKAGAVLTDVFTHLFRNALDHGIEQ
PDVRRLEGKPAAGRITVDVITDEQGLRVTLADDGRGLSLGRIRSIAIARGWLQANQACSDAELAQFIFRAGFSTAQNVTA
VSGRGVGMEAVLAFLQREGGNVSLHFTDDSEGATFRPFETIVRLPQRYIVDAAGLEGRHPQADRAAVPQPMEA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=135, Percent_Identity=41.4814814814815, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86355; Mature: 86224

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50885 HAMP ; PS50894 HPT ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRHRITLLIMLAFLSLAGIGGYAVYQTRGSAAQVKEVTEGVVPSALASADVVALVKDV
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QLATMALVYAPDAALVAQSQAELKDHQAALSMALASQAEHAHTQAQRGLVEQARESFGNY
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAIRETAEMKAAGRDELAQAFLFANVARYRDEMEKIVQTLRVEKNREKDEAITALNGLM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
STTTTAIGVVSGIAVLLLVGVGMVLYRQIARPLTRMQAMMSEIADSQDFSRRVPVGSADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHH
IGRSIIAFNSMIERIQENAGLLRQKTTDMQAILQNMQQGILTVVPGAVVHPEYSKFLEQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHH
LETHEIEGRHVMELIFAHSDISAELASQVDAAIDACLGQDLMNFDFNEHLLVKEVTRRMP
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
DGSVKVLDLSWSPITDEHDNIVRLMLCLRDVTQLRKLAAEASEQKQDLEIIGEILAVNEA
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
SFSRFMESAVGFARENERILRQNVQADIDAVNALFRNMHTVKGNARTHQFRHIAEVAHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EQSYDSLRSAAAQGNWDKDRLLDELERVHDALGRYAMISESRLGRSMQGGGSAVGMPSAD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EEAIRATLALVEQSDPTSLRELAAMRDAVHRNLSCLGTVSVDHALSGVIDSLPSLATELG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
KAAPAVQVNGGGQRVVAKAGAVLTDVFTHLFRNALDHGIEQPDVRRLEGKPAAGRITVDV
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEE
ITDEQGLRVTLADDGRGLSLGRIRSIAIARGWLQANQACSDAELAQFIFRAGFSTAQNVT
EECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCE
AVSGRGVGMEAVLAFLQREGGNVSLHFTDDSEGATFRPFETIVRLPQRYIVDAAGLEGRH
ECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCC
PQADRAAVPQPMEA
CCCCCCCCCCCCCC
>Mature Secondary Structure 
SIRHRITLLIMLAFLSLAGIGGYAVYQTRGSAAQVKEVTEGVVPSALASADVVALVKDV
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QLATMALVYAPDAALVAQSQAELKDHQAALSMALASQAEHAHTQAQRGLVEQARESFGNY
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAIRETAEMKAAGRDELAQAFLFANVARYRDEMEKIVQTLRVEKNREKDEAITALNGLM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
STTTTAIGVVSGIAVLLLVGVGMVLYRQIARPLTRMQAMMSEIADSQDFSRRVPVGSADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHH
IGRSIIAFNSMIERIQENAGLLRQKTTDMQAILQNMQQGILTVVPGAVVHPEYSKFLEQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHH
LETHEIEGRHVMELIFAHSDISAELASQVDAAIDACLGQDLMNFDFNEHLLVKEVTRRMP
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
DGSVKVLDLSWSPITDEHDNIVRLMLCLRDVTQLRKLAAEASEQKQDLEIIGEILAVNEA
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
SFSRFMESAVGFARENERILRQNVQADIDAVNALFRNMHTVKGNARTHQFRHIAEVAHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EQSYDSLRSAAAQGNWDKDRLLDELERVHDALGRYAMISESRLGRSMQGGGSAVGMPSAD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EEAIRATLALVEQSDPTSLRELAAMRDAVHRNLSCLGTVSVDHALSGVIDSLPSLATELG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
KAAPAVQVNGGGQRVVAKAGAVLTDVFTHLFRNALDHGIEQPDVRRLEGKPAAGRITVDV
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEE
ITDEQGLRVTLADDGRGLSLGRIRSIAIARGWLQANQACSDAELAQFIFRAGFSTAQNVT
EECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCE
AVSGRGVGMEAVLAFLQREGGNVSLHFTDDSEGATFRPFETIVRLPQRYIVDAAGLEGRH
ECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCC
PQADRAAVPQPMEA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9255518; 9665876 [H]