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The map label for this gene is dppA [H]

Identifier: 73541611

GI number: 73541611

Start: 2107937

End: 2108755

Strand: Reverse

Name: dppA [H]

Synonym: Reut_A1922

Alternate gene names: 73541611

Gene position: 2108755-2107937 (Counterclockwise)

Preceding gene: 73541612

Following gene: 73541610

Centisome position: 55.4

GC content: 65.69

Gene sequence:

>819_bases
ATGAAGCTGCTGATCTCCACCGATATCGAAGGTATTGCCGGCGTTTTTCACGCCGAGCAGACGCGTCCGGGCAATGGCGA
ATATGAGCGAGCCCGTGCATGGATGACCGGCGAAGCCAATGCGGCCGTGCAGGGCGCCTTCGACGCCGGCGCGACCGCGG
TGCTGGTCAACGACTCGCACGGCGGTTTCCGCAATCTGCTGCCGGACCAGATCGATTCACGTGCGCAGCTCGTACTCGGC
AAGCCCCGCTATCTGGGCATGATGGCCGGCGTGGAAACAGGCTGTGACGGCGTGTTCCTGATTGGCTATCACTGCCGCGC
GCAAAGTCGCGGGGTGCTGGCACACACGATCAACAGCAGCGCGTTTGCGCGCGTGTGGTTGAACGAGCAGGAACTGGGCG
AAGCCGGCCTGTACGCCGCGCTGGCCGGTGAGTTCGGTGTGCCGGTGCTGATGGCCAGTGGCGACGATGTCTTTATCGGC
GAGAGCCGCCCGCTGATGCCGTGGGTGCGCTATGTGCAGACCAAGTCGGCGGGCGGCTTCGGCAGCGGCAGCACGCTCGC
GCCGGCGGCGGCGCGCGATGCTGTTCGGAAAGCGGCGTCGCAAGCTGTACGCGACCGGGCCGATGCAACGCCATTCCGAA
TCGACGGCCCCGTGACCTGCCGGCTCCAGACCCAGACAGCCGCCCACGCGGACCTGTTCTGCCAGTGGCCGACGCTGGAG
CGCGTCGATGGCGTCACGTTGTCGTTCTCAGCCGATTCCGTGCAGTCGGCCGTGCGCATGCTGAACTGCCTGTCGGCGAT
GTCGTTCATGCTGAAATAG

Upstream 100 bases:

>100_bases
CCATCCTTCACGCACTCTGGCAGGCGGTGCCCGTCCATGGCCGTAGCGGACACCGCCGTCAGGCGTTGCTCGATGTCATG
CCCGAACTACGCACTCCAAT

Downstream 100 bases:

>100_bases
CGGCATTGGCCGGGTCGCGGCGCGATCGGCGACAATAACGGGTTGGGCGCGGGCTGGTCTGTTGGCCGGCCTCGCTGTCT
TTACCCGAAATACCGCATTA

Product: D-aminopeptidase DppA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKLLISTDIEGIAGVFHAEQTRPGNGEYERARAWMTGEANAAVQGAFDAGATAVLVNDSHGGFRNLLPDQIDSRAQLVLG
KPRYLGMMAGVETGCDGVFLIGYHCRAQSRGVLAHTINSSAFARVWLNEQELGEAGLYAALAGEFGVPVLMASGDDVFIG
ESRPLMPWVRYVQTKSAGGFGSGSTLAPAAARDAVRKAASQAVRDRADATPFRIDGPVTCRLQTQTAAHADLFCQWPTLE
RVDGVTLSFSADSVQSAVRMLNCLSAMSFMLK

Sequences:

>Translated_272_residues
MKLLISTDIEGIAGVFHAEQTRPGNGEYERARAWMTGEANAAVQGAFDAGATAVLVNDSHGGFRNLLPDQIDSRAQLVLG
KPRYLGMMAGVETGCDGVFLIGYHCRAQSRGVLAHTINSSAFARVWLNEQELGEAGLYAALAGEFGVPVLMASGDDVFIG
ESRPLMPWVRYVQTKSAGGFGSGSTLAPAAARDAVRKAASQAVRDRADATPFRIDGPVTCRLQTQTAAHADLFCQWPTLE
RVDGVTLSFSADSVQSAVRMLNCLSAMSFMLK
>Mature_272_residues
MKLLISTDIEGIAGVFHAEQTRPGNGEYERARAWMTGEANAAVQGAFDAGATAVLVNDSHGGFRNLLPDQIDSRAQLVLG
KPRYLGMMAGVETGCDGVFLIGYHCRAQSRGVLAHTINSSAFARVWLNEQELGEAGLYAALAGEFGVPVLMASGDDVFIG
ESRPLMPWVRYVQTKSAGGFGSGSTLAPAAARDAVRKAASQAVRDRADATPFRIDGPVTCRLQTQTAAHADLFCQWPTLE
RVDGVTLSFSADSVQSAVRMLNCLSAMSFMLK

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 28974; Mature: 28974

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLISTDIEGIAGVFHAEQTRPGNGEYERARAWMTGEANAAVQGAFDAGATAVLVNDSH
CEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHEEECCCCCCEEEECCCCCCEEEEEECCC
GGFRNLLPDQIDSRAQLVLGKPRYLGMMAGVETGCDGVFLIGYHCRAQSRGVLAHTINSS
CCHHHCCCHHHCCCEEEEECCCHHHHEECCCCCCCCEEEEEEEEECCCCCCEEEEEECCC
AFARVWLNEQELGEAGLYAALAGEFGVPVLMASGDDVFIGESRPLMPWVRYVQTKSAGGF
EEEEEEECHHHHCCHHHHHHHHCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHCCCCCC
GSGSTLAPAAARDAVRKAASQAVRDRADATPFRIDGPVTCRLQTQTAAHADLFCQWPTLE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCEEEEECCCHH
RVDGVTLSFSADSVQSAVRMLNCLSAMSFMLK
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLISTDIEGIAGVFHAEQTRPGNGEYERARAWMTGEANAAVQGAFDAGATAVLVNDSH
CEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHEEECCCCCCEEEECCCCCCEEEEEECCC
GGFRNLLPDQIDSRAQLVLGKPRYLGMMAGVETGCDGVFLIGYHCRAQSRGVLAHTINSS
CCHHHCCCHHHCCCEEEEECCCHHHHEECCCCCCCCEEEEEEEEECCCCCCEEEEEECCC
AFARVWLNEQELGEAGLYAALAGEFGVPVLMASGDDVFIGESRPLMPWVRYVQTKSAGGF
EEEEEEECHHHHCCHHHHHHHHCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHCCCCCC
GSGSTLAPAAARDAVRKAASQAVRDRADATPFRIDGPVTCRLQTQTAAHADLFCQWPTLE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCEEEEECCCHH
RVDGVTLSFSADSVQSAVRMLNCLSAMSFMLK
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]