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The map label for this gene is paaG [C]

Identifier: 73541593

GI number: 73541593

Start: 2088538

End: 2089356

Strand: Reverse

Name: paaG [C]

Synonym: Reut_A1904

Alternate gene names: 73541593

Gene position: 2089356-2088538 (Counterclockwise)

Preceding gene: 73541594

Following gene: 73541591

Centisome position: 54.89

GC content: 64.35

Gene sequence:

>819_bases
ATGTATCAGCAGATTTCAGTGACCCGCTCGGGCCGGAACGAGCACGTCGCCATCGTGACCATGAACCGGCCGGACAAACT
CAATGCGCTGACCAAGGTCATGGAGGCCGAACTGCGCGAAGCCATGGAGGCCGCGGACCGCGACGACACCATCCGCGTCG
TGGTGCTGACCGGTGCCGGCAAGGGCTTCTGTGCCGGCATGGACATCAACGAACTTGAGGTCCTGCCCCCTGGCGACATC
CGTGCTGCCCAGTGGATGCGGCCGTACGACATGAACCGCCGCGCCGACTACCAGACCCGCTACGGCTACTTTCCGGCGAT
GCGCAAGCCAGTGATTGCTGCCATCAACGGCGCGGCTGCCGGCCTTGGAATGGTGTTCGCGCTATACAGCGATATGCGCT
TCGCCAGCGACAAGGCGGCCTTCAGCACCGCCTTTGCACGGCGCGGCCTGATTGCCGAGCATGGGATCTCCTGGCTGCTG
CCGCGTGTGGTGGGGCCGGGGCATGCGGCAGACCTGCTGTACTCCGCGCGCAAGGTACCGGCGGATGAAGCCTTGCGCAT
GGGGCTGGTGGATCGCGTGTGCGAGGCCGATGACCTGATGGCGCATACGCTGGCCTATGCCGACGACCTGGCCGAAAACG
TCTCTCCGCGTTCCATCGGCGTGATGAAGCGCCAGCTCTGGGCGCAGCCGTTCCAGACGCTGGCAGAAGCCACCCAGATG
GCCAATGCGGAAATGTTCGACAGCATCCAGAGCGAGGACTTTACCGAAGGCGTGGCGCATTTCATCGAACGCCGTCCGGC
TCGGTTCAGCGGGAGATGA

Upstream 100 bases:

>100_bases
TCCGGCGTTGGCCGCGAAGGCGGTGTCTATGGGCTCGAAGAGTTCCTGGAACCGCGCGCCATCCAGTTTCCCCGCTAAGT
CAAACTTCAGGATATCCAGC

Downstream 100 bases:

>100_bases
TGGCTGGGGAAGCGACGGGGCTTTTCGGTCTTGCTGTCAAGCCTGCGTCGACGCCATCATCAAGGTCTTGGGCTCCAGGT
ACGCACTGATGCCCCATTTC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MYQQISVTRSGRNEHVAIVTMNRPDKLNALTKVMEAELREAMEAADRDDTIRVVVLTGAGKGFCAGMDINELEVLPPGDI
RAAQWMRPYDMNRRADYQTRYGYFPAMRKPVIAAINGAAAGLGMVFALYSDMRFASDKAAFSTAFARRGLIAEHGISWLL
PRVVGPGHAADLLYSARKVPADEALRMGLVDRVCEADDLMAHTLAYADDLAENVSPRSIGVMKRQLWAQPFQTLAEATQM
ANAEMFDSIQSEDFTEGVAHFIERRPARFSGR

Sequences:

>Translated_272_residues
MYQQISVTRSGRNEHVAIVTMNRPDKLNALTKVMEAELREAMEAADRDDTIRVVVLTGAGKGFCAGMDINELEVLPPGDI
RAAQWMRPYDMNRRADYQTRYGYFPAMRKPVIAAINGAAAGLGMVFALYSDMRFASDKAAFSTAFARRGLIAEHGISWLL
PRVVGPGHAADLLYSARKVPADEALRMGLVDRVCEADDLMAHTLAYADDLAENVSPRSIGVMKRQLWAQPFQTLAEATQM
ANAEMFDSIQSEDFTEGVAHFIERRPARFSGR
>Mature_272_residues
MYQQISVTRSGRNEHVAIVTMNRPDKLNALTKVMEAELREAMEAADRDDTIRVVVLTGAGKGFCAGMDINELEVLPPGDI
RAAQWMRPYDMNRRADYQTRYGYFPAMRKPVIAAINGAAAGLGMVFALYSDMRFASDKAAFSTAFARRGLIAEHGISWLL
PRVVGPGHAADLLYSARKVPADEALRMGLVDRVCEADDLMAHTLAYADDLAENVSPRSIGVMKRQLWAQPFQTLAEATQM
ANAEMFDSIQSEDFTEGVAHFIERRPARFSGR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=268, Percent_Identity=29.1044776119403, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI70995211, Length=273, Percent_Identity=31.1355311355311, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI260274832, Length=254, Percent_Identity=27.9527559055118, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI45643119, Length=254, Percent_Identity=27.9527559055118, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260275230, Length=254, Percent_Identity=27.9527559055118, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI68989263, Length=219, Percent_Identity=29.6803652968037, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31542718, Length=252, Percent_Identity=26.984126984127, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI116235487, Length=171, Percent_Identity=32.1637426900585, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI221136756, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221136753, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221307494, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757968, Length=177, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI49355787, Length=177, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=28.1368821292776, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=34.2307692307692, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787659, Length=266, Percent_Identity=30.0751879699248, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI221142681, Length=283, Percent_Identity=30.0353356890459, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082183, Length=285, Percent_Identity=29.8245614035088, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=29.296875, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788682, Length=217, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790281, Length=203, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=266, Percent_Identity=31.9548872180451, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17554946, Length=270, Percent_Identity=25.9259259259259, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17535521, Length=260, Percent_Identity=27.6923076923077, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534483, Length=211, Percent_Identity=32.7014218009479, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=182, Percent_Identity=32.4175824175824, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=209, Percent_Identity=32.0574162679426, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=222, Percent_Identity=31.5315315315315, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=186, Percent_Identity=36.0215053763441, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=273, Percent_Identity=28.2051282051282, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20129971, Length=269, Percent_Identity=29.368029739777, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24653477, Length=269, Percent_Identity=29.368029739777, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24653139, Length=268, Percent_Identity=28.7313432835821, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24654903, Length=264, Percent_Identity=24.2424242424242, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=29.7619047619048, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357171, Length=251, Percent_Identity=27.4900398406374, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650670, Length=204, Percent_Identity=28.4313725490196, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19922422, Length=260, Percent_Identity=28.4615384615385, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30151; Mature: 30151

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQQISVTRSGRNEHVAIVTMNRPDKLNALTKVMEAELREAMEAADRDDTIRVVVLTGAG
CCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
KGFCAGMDINELEVLPPGDIRAAQWMRPYDMNRRADYQTRYGYFPAMRKPVIAAINGAAA
CCEEECCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCHHCCCCHHHHCCHHHHHCCHHH
GLGMVFALYSDMRFASDKAAFSTAFARRGLIAEHGISWLLPRVVGPGHAADLLYSARKVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHCCCCHHHHHHHHHHCCC
ADEALRMGLVDRVCEADDLMAHTLAYADDLAENVSPRSIGVMKRQLWAQPFQTLAEATQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ANAEMFDSIQSEDFTEGVAHFIERRPARFSGR
HCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYQQISVTRSGRNEHVAIVTMNRPDKLNALTKVMEAELREAMEAADRDDTIRVVVLTGAG
CCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
KGFCAGMDINELEVLPPGDIRAAQWMRPYDMNRRADYQTRYGYFPAMRKPVIAAINGAAA
CCEEECCCCCCEECCCCCCCCHHHHCCCCCCCCCCCCCHHCCCCHHHHCCHHHHHCCHHH
GLGMVFALYSDMRFASDKAAFSTAFARRGLIAEHGISWLLPRVVGPGHAADLLYSARKVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHCCCCHHHHHHHHHHCCC
ADEALRMGLVDRVCEADDLMAHTLAYADDLAENVSPRSIGVMKRQLWAQPFQTLAEATQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ANAEMFDSIQSEDFTEGVAHFIERRPARFSGR
HCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA