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The map label for this gene is qmcA [H]

Identifier: 73541551

GI number: 73541551

Start: 2037298

End: 2038227

Strand: Reverse

Name: qmcA [H]

Synonym: Reut_A1862

Alternate gene names: 73541551

Gene position: 2038227-2037298 (Counterclockwise)

Preceding gene: 73541552

Following gene: 73541549

Centisome position: 53.55

GC content: 61.51

Gene sequence:

>930_bases
ATGGAAGTCTTTCAGCTTGGCCTGTTGCCGCTGATTATCCTGATTGCCGCGATCGTGCTGATTGCGAAGGGCATCAAGAT
CGTGCCGCAGCAGCACGCTTGGGTGCTCGAGCGTCTGGGGCGCTATCACGCGACGCTGACTCCGGGGCTGTCGATCGTGG
TGCCGTTCATCGATCGCGTCGCCTACAAGCACATCCTGAAGGAAATCCCGCTCGACGTGCCCAGCCAGGTCTGCATCACG
AAGGACAATACGCAGCTGCAGGTCGATGGTGTGCTGTACTTCCAGGTCACGGATCCGATGAAGGCCTCGTATGGGTCGAG
CAACTTTGTCGTGGCCATCACCCAGCTGTCGCAAACCACGCTGCGCTCGGTCATCGGCAAGCTGGAGCTCGACAAGACGT
TCGAGGAGCGGGAGTTCATCAATCACAGCGTGGTCAACGCGCTCGACGAGGCGGCTTCGAACTGGGGCGTGAAGGTACTG
CGCTATGAGATCAAGGATCTGACGCCGCCGAAGGAAATCCTGCACGCGATGCAGGCCCAGATCACCGCGGAGCGCGAAAA
GCGCGCGCTGATCGCAGCATCGGAAGGCAAGCGCCAGGAGCAGATCAACCTGGCGTCGGGCGCGCGTGAAGCGGCCATTC
AGAAATCGGAAGGTGAGAAGCAGGCCGCTATCAACAAGGCGCAGGGCGAGGCCGCGGCCATCCTGGCGGTGGCGGAGGCC
AACGCGCAGGCGATCCAGAAGATCGGTCAGGCCATTCGCGTGGATGGCGGCATGGAAGCCGTGAACCTCAAGGTGGCCGA
GGAATACGTCACGGCGTTCGGTAATCTCGCCAAACAGGGCAACACGCTGATCGTGCCGGGCGACCTCGGCGAGATGAGCA
GCATGATTGCCTCGGCGCTGCAGATTGTGAAAGGCCAGAAGGCCGTCTGA

Upstream 100 bases:

>100_bases
TGATTGTCCTGCCGCGCTGATTGCCATTGTTGCTGCGCGCCGTTGCGCGGCATTGTTGTCCGTTGTCGTCCGTTTTGGTC
AACTGTCCGGAGGGTCTTAC

Downstream 100 bases:

>100_bases
GAACGTAGCGAAACTGCGGGGCCCGAGCGCGTTACTCCTTGCTGCCGCCCTTCATGATGCGTGACTTCTCGCGCTGCCAG
TCGCGTTGCTTCTCGGTTTC

Product: SPFH domain-containing protein/band 7 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MEVFQLGLLPLIILIAAIVLIAKGIKIVPQQHAWVLERLGRYHATLTPGLSIVVPFIDRVAYKHILKEIPLDVPSQVCIT
KDNTQLQVDGVLYFQVTDPMKASYGSSNFVVAITQLSQTTLRSVIGKLELDKTFEEREFINHSVVNALDEAASNWGVKVL
RYEIKDLTPPKEILHAMQAQITAEREKRALIAASEGKRQEQINLASGAREAAIQKSEGEKQAAINKAQGEAAAILAVAEA
NAQAIQKIGQAIRVDGGMEAVNLKVAEEYVTAFGNLAKQGNTLIVPGDLGEMSSMIASALQIVKGQKAV

Sequences:

>Translated_309_residues
MEVFQLGLLPLIILIAAIVLIAKGIKIVPQQHAWVLERLGRYHATLTPGLSIVVPFIDRVAYKHILKEIPLDVPSQVCIT
KDNTQLQVDGVLYFQVTDPMKASYGSSNFVVAITQLSQTTLRSVIGKLELDKTFEEREFINHSVVNALDEAASNWGVKVL
RYEIKDLTPPKEILHAMQAQITAEREKRALIAASEGKRQEQINLASGAREAAIQKSEGEKQAAINKAQGEAAAILAVAEA
NAQAIQKIGQAIRVDGGMEAVNLKVAEEYVTAFGNLAKQGNTLIVPGDLGEMSSMIASALQIVKGQKAV
>Mature_309_residues
MEVFQLGLLPLIILIAAIVLIAKGIKIVPQQHAWVLERLGRYHATLTPGLSIVVPFIDRVAYKHILKEIPLDVPSQVCIT
KDNTQLQVDGVLYFQVTDPMKASYGSSNFVVAITQLSQTTLRSVIGKLELDKTFEEREFINHSVVNALDEAASNWGVKVL
RYEIKDLTPPKEILHAMQAQITAEREKRALIAASEGKRQEQINLASGAREAAIQKSEGEKQAAINKAQGEAAAILAVAEA
NAQAIQKIGQAIRVDGGMEAVNLKVAEEYVTAFGNLAKQGNTLIVPGDLGEMSSMIASALQIVKGQKAV

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=276, Percent_Identity=50.3623188405797, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI221316744, Length=200, Percent_Identity=35.5, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI21686995, Length=208, Percent_Identity=35.0961538461538, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI38016911, Length=210, Percent_Identity=34.7619047619048, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7657615, Length=187, Percent_Identity=25.668449197861, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786697, Length=293, Percent_Identity=41.9795221843003, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1790616, Length=214, Percent_Identity=25.7009345794392, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32564147, Length=281, Percent_Identity=47.6868327402135, Blast_Score=278, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI17569493, Length=222, Percent_Identity=34.6846846846847, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193209764, Length=222, Percent_Identity=34.6846846846847, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17569497, Length=204, Percent_Identity=32.3529411764706, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193210507, Length=192, Percent_Identity=32.2916666666667, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17570161, Length=192, Percent_Identity=32.2916666666667, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71987612, Length=163, Percent_Identity=33.1288343558282, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25153583, Length=163, Percent_Identity=33.1288343558282, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71989955, Length=155, Percent_Identity=34.8387096774194, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71989948, Length=155, Percent_Identity=34.8387096774194, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987621, Length=166, Percent_Identity=32.5301204819277, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17569499, Length=187, Percent_Identity=34.2245989304813, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32566490, Length=170, Percent_Identity=32.3529411764706, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17570459, Length=187, Percent_Identity=33.1550802139037, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45550506, Length=278, Percent_Identity=49.2805755395683, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI45556022, Length=162, Percent_Identity=35.8024691358025, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI18860517, Length=204, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573263, Length=199, Percent_Identity=28.643216080402, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI62484448, Length=172, Percent_Identity=33.1395348837209, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356845, Length=195, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI62484274, Length=172, Percent_Identity=33.1395348837209, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281365664, Length=172, Percent_Identity=33.1395348837209, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281361631, Length=198, Percent_Identity=26.2626262626263, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281361633, Length=198, Percent_Identity=26.2626262626263, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24657857, Length=172, Percent_Identity=33.1395348837209, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33509; Mature: 33509

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVFQLGLLPLIILIAAIVLIAKGIKIVPQQHAWVLERLGRYHATLTPGLSIVVPFIDRV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AYKHILKEIPLDVPSQVCITKDNTQLQVDGVLYFQVTDPMKASYGSSNFVVAITQLSQTT
HHHHHHHHCCCCCCCCEEEECCCCEEEEEEEEEEEECCCHHHCCCCCCEEEEEEHHHHHH
LRSVIGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRYEIKDLTPPKEILHAMQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHH
ITAEREKRALIAASEGKRQEQINLASGAREAAIQKSEGEKQAAINKAQGEAAAILAVAEA
HHHHHHHHEEEEECCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEHHC
NAQAIQKIGQAIRVDGGMEAVNLKVAEEYVTAFGNLAKQGNTLIVPGDLGEMSSMIASAL
CHHHHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
QIVKGQKAV
HHHCCCCCC
>Mature Secondary Structure
MEVFQLGLLPLIILIAAIVLIAKGIKIVPQQHAWVLERLGRYHATLTPGLSIVVPFIDRV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AYKHILKEIPLDVPSQVCITKDNTQLQVDGVLYFQVTDPMKASYGSSNFVVAITQLSQTT
HHHHHHHHCCCCCCCCEEEECCCCEEEEEEEEEEEECCCHHHCCCCCCEEEEEEHHHHHH
LRSVIGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRYEIKDLTPPKEILHAMQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHH
ITAEREKRALIAASEGKRQEQINLASGAREAAIQKSEGEKQAAINKAQGEAAAILAVAEA
HHHHHHHHEEEEECCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEHHC
NAQAIQKIGQAIRVDGGMEAVNLKVAEEYVTAFGNLAKQGNTLIVPGDLGEMSSMIASAL
CHHHHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
QIVKGQKAV
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]