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The map label for this gene is uvrY [H]

Identifier: 73541474

GI number: 73541474

Start: 1948204

End: 1948824

Strand: Reverse

Name: uvrY [H]

Synonym: Reut_A1785

Alternate gene names: 73541474

Gene position: 1948824-1948204 (Counterclockwise)

Preceding gene: 73541475

Following gene: 73541473

Centisome position: 51.2

GC content: 65.38

Gene sequence:

>621_bases
ATGAAAACGATCGACGTAGTGATCACCGATGATCACGCAGTGGTGCGCACCGGCTACCGTCGCCTGCTGGAACTGGACGA
GGGGATGCGTGTGGTGGCGGAGTTCGGCGATGCCGATACTGCCTACGACTGGCTGGTCCGCAATCGGGCTGACGTGCTGA
TCCTTGACCTGTCCATGCCCGGCCGCGGCGGCCTGGAGATGCTCCAGCGGCTGCGTATACGCGTTCCCGCGCTGCACACG
CTGGTGTTCAGCATGCACGACAGCGCCGCCATCGTGATGCAGGCGATGCGCGCCGGGGCGGTTGGCTATCTGACCAAGAA
CAGCGCGCCGGAGGCGCTGGTGGACGCTGTACGCAGGGTGGCGGGCGGCCTGCGGGTGCTGTCCGATGACATCGCCGGCC
TGCTCGACACGGGTGGGCAGCCGCCCCACCTTGCGTTGTCGCCGCGGGAGTTCGACCTGTTCCGTCAGTTCGCGCGTGGC
ACCGCGCTTGAGGACGTCGCTGCGCGCTTCTGCCTCAGTACCAAGACCGTGGCCAACTACCAGACGCTCATCCGCAAGAA
GATGGGACTGGCCAACCGCATCGAGATGCATCGCTATGCGGTGGAGCATGGTTTCGGTTGA

Upstream 100 bases:

>100_bases
CGCAGATCCCGCCAATCCCGCCAATCCCGCCAATCCCGCCAATCCCGCCAATCCCGCCGGTCCCGCCGGTCCCGCAAATT
CACCAGGGGAGCCAGCCAGC

Downstream 100 bases:

>100_bases
CCGGCCAGGCTGTTGGCGGTTGCTCAGTTCTGGAGCAGATGCAACGCAGTGTTGCGCGCTGACACGGTCGCACAGCGCTT
TGCGGCCGCAGCCGGCCGGT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKTIDVVITDDHAVVRTGYRRLLELDEGMRVVAEFGDADTAYDWLVRNRADVLILDLSMPGRGGLEMLQRLRIRVPALHT
LVFSMHDSAAIVMQAMRAGAVGYLTKNSAPEALVDAVRRVAGGLRVLSDDIAGLLDTGGQPPHLALSPREFDLFRQFARG
TALEDVAARFCLSTKTVANYQTLIRKKMGLANRIEMHRYAVEHGFG

Sequences:

>Translated_206_residues
MKTIDVVITDDHAVVRTGYRRLLELDEGMRVVAEFGDADTAYDWLVRNRADVLILDLSMPGRGGLEMLQRLRIRVPALHT
LVFSMHDSAAIVMQAMRAGAVGYLTKNSAPEALVDAVRRVAGGLRVLSDDIAGLLDTGGQPPHLALSPREFDLFRQFARG
TALEDVAARFCLSTKTVANYQTLIRKKMGLANRIEMHRYAVEHGFG
>Mature_206_residues
MKTIDVVITDDHAVVRTGYRRLLELDEGMRVVAEFGDADTAYDWLVRNRADVLILDLSMPGRGGLEMLQRLRIRVPALHT
LVFSMHDSAAIVMQAMRAGAVGYLTKNSAPEALVDAVRRVAGGLRVLSDDIAGLLDTGGQPPHLALSPREFDLFRQFARG
TALEDVAARFCLSTKTVANYQTLIRKKMGLANRIEMHRYAVEHGFG

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=32.2115384615385, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790102, Length=195, Percent_Identity=40, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=35.0515463917526, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=30.3921568627451, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=25, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787473, Length=179, Percent_Identity=30.7262569832402, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=22.8155339805825, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22777; Mature: 22777

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIDVVITDDHAVVRTGYRRLLELDEGMRVVAEFGDADTAYDWLVRNRADVLILDLSMP
CCEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCC
GRGGLEMLQRLRIRVPALHTLVFSMHDSAAIVMQAMRAGAVGYLTKNSAPEALVDAVRRV
CCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
AGGLRVLSDDIAGLLDTGGQPPHLALSPREFDLFRQFARGTALEDVAARFCLSTKTVANY
HHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QTLIRKKMGLANRIEMHRYAVEHGFG
HHHHHHHHCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTIDVVITDDHAVVRTGYRRLLELDEGMRVVAEFGDADTAYDWLVRNRADVLILDLSMP
CCEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCC
GRGGLEMLQRLRIRVPALHTLVFSMHDSAAIVMQAMRAGAVGYLTKNSAPEALVDAVRRV
CCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
AGGLRVLSDDIAGLLDTGGQPPHLALSPREFDLFRQFARGTALEDVAARFCLSTKTVANY
HHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QTLIRKKMGLANRIEMHRYAVEHGFG
HHHHHHHHCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]