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The map label for this gene is exaA [H]

Identifier: 73541473

GI number: 73541473

Start: 1946263

End: 1948005

Strand: Reverse

Name: exaA [H]

Synonym: Reut_A1784

Alternate gene names: 73541473

Gene position: 1948005-1946263 (Counterclockwise)

Preceding gene: 73541474

Following gene: 73541472

Centisome position: 51.18

GC content: 64.37

Gene sequence:

>1743_bases
ATGAGGACGTTACGACTAATGATGGCCGTCGCGACCGCCGTGGCCAGTCTGGCCACTCAGGCGGCAGTGACCGATGCCAT
GATCGAGAACGATGCGAAGAGCCCCGGCGACGTGTTGTCATGGGGCATGGGACCGCAAGGGCAGCGCTATTCCGGCCTCA
CGCGCATCAATACCAAAAACGTCGGCAACCTGGTGCCGGCGTGGTCGTTCTCGTTCGGCGGCGAGAAGCAGCGCGGGCAG
GAAGCGCAGCCGCTGATCCACGACGGCAAGATGTTCGTCACGGCGTCGTATTCGCGCATCTACGCGCTCGACCTGAAGAC
CGGCAGCAAATTGTGGAAGTACGAACACCGCCTGCCGGAAGGCATCATGCCGTGCTGCGACGTGGTCAACCGCGGCGCGG
CGCTCTACGACAACCTGGTGATCTTCGGCACGCTCGATGCGCAACTGGTGGCACTGGACCAGAAGACCGGCAAGGTCGTG
TGGAAGGAGAAGCTGGAGGACTATGCAGCAGGCTATTCCTATACGGCGGCGCCGCTGATCGTCAAGGGCATGGTGCTCAC
CGGCATCTCGGGCGGCGAATTCGGTGTGGTCGGCCGCGTCGAGGCCCGCGACGCCAAGACCGGGCAACTGGTGTGGTCGC
GCCCCGTGGTGGAAGGCCATATGGGCTACAAGTACGACAAGGACGGCAACAAGACCGAGAACGGCGTGACCGGCACGGAG
AACGCAAGTTGGCCCGGCGAAACGTGGAAGACCGGCGGTGCCGCCACGTGGCTCGGCGGCACCTATGATCCGGCCACCGG
TCTCGCTTACTTCGGGACCGGCAACCCCGGCCCGTGGAATAGCCATATCCGCAAGGGGGACAACCTCTATTCGGCGTCGA
CGGTGGCCATCGATCCGGCCACCGGCAAGATCGTCTGGCACTACCAGAACACCCCGAACGACGGCTGGGATTTTGACGGC
GTCAATGAGTTCGTGACCTTCGACCTGGACGGCAAGCGCATGGGCGGCAAGGCCGACCGCAACGGCTTCTTCTATGTCAA
CGATGCGACCAACGGCAAACTGGTCAATGCCTTCCCGTTCGTGAAGAAGATCACGTGGGCCACTGGCATCGACCTGAAGA
CCGGTCGGCCCACCTTCAACGACGAGGGTCGCCCGGGCGATCCGGCCAGCGGCGCCGACCCGAAGAAGGGCAAGTCCGTG
TTCGCCGCGCCCGGCTTCCTGGGTGGCAAGAACCAGCAGCCAATGGCCTACAGCCCGCAGACGGGCTTGTTCTACGTGCC
GGCCAACGAATGGGGCATGGATATCTGGAATGAGCCCGTCAGCTACAAGAAGGGCGCCGCCTTCCTGGGTGCCGGATTCA
CCATCCATCCACTGAACGAGGACTACATCGGTTCGCTGCGCGCCATCAACCCCAAGACCGGCAAGATCGTCTGGGAGGTC
AAGAACAACGCGCCGCTGTGGGGCGGTGTGATGACCACCGCCGGCGGGCTGGTGTTCTGGGGCACGCCGGAAGGCTACCT
CAAGGCCGCCGACGCCCGGACCGGCAAGGAGCTGTGGAAGTTCCAGACCGGCAGTGGCGTGGTCGCGCCGCCGGTCACCT
GGGAAGAGAACGGCGAGCAGTATGTCGCCGTGGTGTCGGGCTGGGGCGGTGCGGTGCCGCTGTGGGGCGGGGAAGTCGCC
AAGCGCGTGAATTTCCTGGAGCAGGGCGGTTCGGTGTGGGTGTTCAAGCTGCACAAGGGCTGA

Upstream 100 bases:

>100_bases
GTTTTGGCGGCGATTCGATTGGCATGGGAATTGCCAACTGCGTGTCGGATGCATGGCGCAGTGGTGCGCCGCGGACACCG
AGAACAATGAGGAGATGACA

Downstream 100 bases:

>100_bases
ACGACAGGCAGGTTGATGGCTGGAGACGCTGGCATCCCTGTGCGGATGCCAGCGTTCTCGCAACGCGAAACAGTGGGATA
CGGTATGAAGATCGAATGGA

Product: Pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MRTLRLMMAVATAVASLATQAAVTDAMIENDAKSPGDVLSWGMGPQGQRYSGLTRINTKNVGNLVPAWSFSFGGEKQRGQ
EAQPLIHDGKMFVTASYSRIYALDLKTGSKLWKYEHRLPEGIMPCCDVVNRGAALYDNLVIFGTLDAQLVALDQKTGKVV
WKEKLEDYAAGYSYTAAPLIVKGMVLTGISGGEFGVVGRVEARDAKTGQLVWSRPVVEGHMGYKYDKDGNKTENGVTGTE
NASWPGETWKTGGAATWLGGTYDPATGLAYFGTGNPGPWNSHIRKGDNLYSASTVAIDPATGKIVWHYQNTPNDGWDFDG
VNEFVTFDLDGKRMGGKADRNGFFYVNDATNGKLVNAFPFVKKITWATGIDLKTGRPTFNDEGRPGDPASGADPKKGKSV
FAAPGFLGGKNQQPMAYSPQTGLFYVPANEWGMDIWNEPVSYKKGAAFLGAGFTIHPLNEDYIGSLRAINPKTGKIVWEV
KNNAPLWGGVMTTAGGLVFWGTPEGYLKAADARTGKELWKFQTGSGVVAPPVTWEENGEQYVAVVSGWGGAVPLWGGEVA
KRVNFLEQGGSVWVFKLHKG

Sequences:

>Translated_580_residues
MRTLRLMMAVATAVASLATQAAVTDAMIENDAKSPGDVLSWGMGPQGQRYSGLTRINTKNVGNLVPAWSFSFGGEKQRGQ
EAQPLIHDGKMFVTASYSRIYALDLKTGSKLWKYEHRLPEGIMPCCDVVNRGAALYDNLVIFGTLDAQLVALDQKTGKVV
WKEKLEDYAAGYSYTAAPLIVKGMVLTGISGGEFGVVGRVEARDAKTGQLVWSRPVVEGHMGYKYDKDGNKTENGVTGTE
NASWPGETWKTGGAATWLGGTYDPATGLAYFGTGNPGPWNSHIRKGDNLYSASTVAIDPATGKIVWHYQNTPNDGWDFDG
VNEFVTFDLDGKRMGGKADRNGFFYVNDATNGKLVNAFPFVKKITWATGIDLKTGRPTFNDEGRPGDPASGADPKKGKSV
FAAPGFLGGKNQQPMAYSPQTGLFYVPANEWGMDIWNEPVSYKKGAAFLGAGFTIHPLNEDYIGSLRAINPKTGKIVWEV
KNNAPLWGGVMTTAGGLVFWGTPEGYLKAADARTGKELWKFQTGSGVVAPPVTWEENGEQYVAVVSGWGGAVPLWGGEVA
KRVNFLEQGGSVWVFKLHKG
>Mature_580_residues
MRTLRLMMAVATAVASLATQAAVTDAMIENDAKSPGDVLSWGMGPQGQRYSGLTRINTKNVGNLVPAWSFSFGGEKQRGQ
EAQPLIHDGKMFVTASYSRIYALDLKTGSKLWKYEHRLPEGIMPCCDVVNRGAALYDNLVIFGTLDAQLVALDQKTGKVV
WKEKLEDYAAGYSYTAAPLIVKGMVLTGISGGEFGVVGRVEARDAKTGQLVWSRPVVEGHMGYKYDKDGNKTENGVTGTE
NASWPGETWKTGGAATWLGGTYDPATGLAYFGTGNPGPWNSHIRKGDNLYSASTVAIDPATGKIVWHYQNTPNDGWDFDG
VNEFVTFDLDGKRMGGKADRNGFFYVNDATNGKLVNAFPFVKKITWATGIDLKTGRPTFNDEGRPGDPASGADPKKGKSV
FAAPGFLGGKNQQPMAYSPQTGLFYVPANEWGMDIWNEPVSYKKGAAFLGAGFTIHPLNEDYIGSLRAINPKTGKIVWEV
KNNAPLWGGVMTTAGGLVFWGTPEGYLKAADARTGKELWKFQTGSGVVAPPVTWEENGEQYVAVVSGWGGAVPLWGGEVA
KRVNFLEQGGSVWVFKLHKG

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=397, Percent_Identity=25.1889168765743, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 62605; Mature: 62605

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLRLMMAVATAVASLATQAAVTDAMIENDAKSPGDVLSWGMGPQGQRYSGLTRINTKN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCEEEECCCC
VGNLVPAWSFSFGGEKQRGQEAQPLIHDGKMFVTASYSRIYALDLKTGSKLWKYEHRLPE
CCCCCCCEEECCCCCHHCCCCCCCEEECCEEEEEEECCEEEEEEECCCCHHHHHHHCCCC
GIMPCCDVVNRGAALYDNLVIFGTLDAQLVALDQKTGKVVWKEKLEDYAAGYSYTAAPLI
CHHHHHHHHHCCCHHHCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHH
VKGMVLTGISGGEFGVVGRVEARDAKTGQLVWSRPVVEGHMGYKYDKDGNKTENGVTGTE
HCCEEEECCCCCCEEEEEEEECCCCCCCCEEEECCCEECCCCCEECCCCCCCCCCCCCCC
NASWPGETWKTGGAATWLGGTYDPATGLAYFGTGNPGPWNSHIRKGDNLYSASTVAIDPA
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHCCCCCEEECEEEEECCC
TGKIVWHYQNTPNDGWDFDGVNEFVTFDLDGKRMGGKADRNGFFYVNDATNGKLVNAFPF
CCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEECCHH
VKKITWATGIDLKTGRPTFNDEGRPGDPASGADPKKGKSVFAAPGFLGGKNQQPMAYSPQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEECCC
TGLFYVPANEWGMDIWNEPVSYKKGAAFLGAGFTIHPLNEDYIGSLRAINPKTGKIVWEV
CCEEEEECCCCCCHHCCCCCCCCCCCEEEECCCEEECCCHHHCCCEEECCCCCCEEEEEE
KNNAPLWGGVMTTAGGLVFWGTPEGYLKAADARTGKELWKFQTGSGVVAPPVTWEENGEQ
CCCCCEECCHHHHCCCEEEECCCCHHEEECCCCCCHHHHEEECCCCEECCCCCCCCCCCE
YVAVVSGWGGAVPLWGGEVAKRVNFLEQGGSVWVFKLHKG
EEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MRTLRLMMAVATAVASLATQAAVTDAMIENDAKSPGDVLSWGMGPQGQRYSGLTRINTKN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCEEEECCCC
VGNLVPAWSFSFGGEKQRGQEAQPLIHDGKMFVTASYSRIYALDLKTGSKLWKYEHRLPE
CCCCCCCEEECCCCCHHCCCCCCCEEECCEEEEEEECCEEEEEEECCCCHHHHHHHCCCC
GIMPCCDVVNRGAALYDNLVIFGTLDAQLVALDQKTGKVVWKEKLEDYAAGYSYTAAPLI
CHHHHHHHHHCCCHHHCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHH
VKGMVLTGISGGEFGVVGRVEARDAKTGQLVWSRPVVEGHMGYKYDKDGNKTENGVTGTE
HCCEEEECCCCCCEEEEEEEECCCCCCCCEEEECCCEECCCCCEECCCCCCCCCCCCCCC
NASWPGETWKTGGAATWLGGTYDPATGLAYFGTGNPGPWNSHIRKGDNLYSASTVAIDPA
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHCCCCCEEECEEEEECCC
TGKIVWHYQNTPNDGWDFDGVNEFVTFDLDGKRMGGKADRNGFFYVNDATNGKLVNAFPF
CCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEECCHH
VKKITWATGIDLKTGRPTFNDEGRPGDPASGADPKKGKSVFAAPGFLGGKNQQPMAYSPQ
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEECCC
TGLFYVPANEWGMDIWNEPVSYKKGAAFLGAGFTIHPLNEDYIGSLRAINPKTGKIVWEV
CCEEEEECCCCCCHHCCCCCCCCCCCEEEECCCEEECCCHHHCCCEEECCCCCCEEEEEE
KNNAPLWGGVMTTAGGLVFWGTPEGYLKAADARTGKELWKFQTGSGVVAPPVTWEENGEQ
CCCCCEECCHHHHCCCEEEECCCCHHEEECCCCCCHHHHEEECCCCEECCCCCCCCCCCE
YVAVVSGWGGAVPLWGGEVAKRVNFLEQGGSVWVFKLHKG
EEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]