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The map label for this gene is betA [H]

Identifier: 73541435

GI number: 73541435

Start: 1889209

End: 1891134

Strand: Reverse

Name: betA [H]

Synonym: Reut_A1746

Alternate gene names: 73541435

Gene position: 1891134-1889209 (Counterclockwise)

Preceding gene: 73541436

Following gene: 73541434

Centisome position: 49.68

GC content: 65.06

Gene sequence:

>1926_bases
ATGTCTGGGGAAGATGAAACAGAATGGGACTACGTAGTCGTAGGTTCCGGCGCGGGCGGCGGTACGCTGGCCGCGCGCCT
GGCAGAGGCGGGCATGCGCGTGTGCGTGCTCGAAGCCGGCTGCGATGCGCGCGCGCATGAGATGTCGTGCATGCCTGAAG
ACTATGACGTGCCCGGCTTTCACGCCTGTGCAAGCGAGAATCCGGCCATGGCATGGAATTTCTTCGTGCGCCACTACACG
GACGACGCGCAACAGCATCGCGATCCCAAATGCGGTCCCGCGGGCGTGCTGTACCCGCGCGCGGGGACGCTTGGCGGTTG
CACTGCGCACAACGCGCTGATCTTCCTGTATCCGCACGATGCGGACTGGGACCACATTGCCGACGTGACCGGCGATCCGT
CATGGACGGCGACTCGCATGCGGAGCTATGCGAAGCGGATCGAGCAATGCCGCCATCGACCGCTTTGGAATCTCGCGCGA
CGGTTCGGCATCGATCCCACGCTGCATGGCTGGGATGGCTGGCTGCATACTGAGCGCGCGATGCCGCTGGAAGCGCTCGC
CGACGACGCACTGGTCCGCGTCATCATCGGTTCGATGGAACTTGCCGCGCGCAGTGTGCCAAGGCGCGTGCGCGCGTGGC
TACGGCTGATTCGCTGGCAAGGTGATCCGAACTCGCGGCTGTGGGGCCGACGCTGTTTTCACGGGGTGTGCTATACGCCG
CTGACCACGCAGCGGCACGCGCGCCACGGTACGCGCGAACGTCTGCTCGATGTGGCCGAGCGGTATCCGGACAGGCTCCG
GATCGAACTCGATGCGCTGGCCACGCGCGTGCTGTTCGACGCGCAGGGCAATGCGTGCGGCGTGGAGTATCTGAAGGGCA
GGCATCTCTATCAAGCCCATGTCAAACCGAGCGATGGGGACGGTGAGCGTTGCCAGGTCCGCGCGCGGCGTGAGGTGATC
CTTGCGGGCGGCGCGTTCAATACCCCGCAACTGTTGATGCTGTCCGGGATCGGCCCGGCCGAGCACCTGCAGGAACATGG
CATTCCGGTGCGCGTGGATCTGACCGGAGTCGGCCGCAATCTGCAGGATCGCTACGAGATTGGCGTCGTGAACCGTATGT
CGCGCTCTTGGGAGGTGCTGCAGGGTGCGAAATTCGTGCGTGACGACGCGCCGTACCAGAGCTGGTTCGATTCGCGCGAC
GGCGTCTACACCACGAATGGCGTGGCAACGGCGGTGATCCGCCGATCGGGCCGGCGCATGCCTGTACCGGACATCTTCTG
CATGGCGCTGCTCGAACGTTTTGTCGGCTACTACCCGGGCTACTCGAAGGTCTTCGCGCAGAACGACAATGTGCTGACGT
GGGCGATCTTGAAGGCGCACACGCGCAACCGTGCCGGCGTGGTGTCGCTGCGCTCGGCCGACCCGCGCGATATGCCCGAC
ATCGATTTCCGCTATTTCGACGGCGCGGATGACCCGCACGGCGATGACATGCGCGCGCTGATCGGCGCTATCCGCTTCGT
ACGCGGGCTGGCGCAACCGCTGGCAGAGCAGGGCTTGATCGCCAACGAAGAACTGCCGGGCGTGGATGTCCAGAGCGACG
AAGCACTGGCCGCCTATATTCGCGACAACGCCTGGGGCCATCACGCATCATGCTCGTGCCCGATTGGCGCGCGCGCAACA
GGCGGCGTGCTCGACAGCAACTTCTGCGTGCATGGCACGCGCCGCCTGCGCGTTGTTGATGCCTCGGCCTTTCCGCGCAT
TCCGGGCTTCTTTCCGGTCAGCGCGATCTACATGATGGCCGAGAAGGCCGCCGACGTACTGCTGGCCACGGCGCAGGCCA
CGCCACCCTTGCCGTTCCCGATAGGAGACCGCCATGGCCTACGACGTGCACAAGCTCCTGCAAATGCAGCAGGCCGAACT
GGATGA

Upstream 100 bases:

>100_bases
TTCGGCAAGGAACCCGTGTTGAGCGACGATGACAAGCGGGCCTTGATCGCCTTCCTGAAGACGTTCTGACGATGCAATGC
CGGCGGCGTAGCGGGGGGCT

Downstream 100 bases:

>100_bases
TCTATTTCGCAACAGCGCCGCTGGAGATATCCCGAACGGCGAGGCAAAGGGCACGGCCATCATCTCGCCGGGCACGACAT
TCAGCGAAAGCATCTCGCGC

Product: glucose-methanol-choline oxidoreductase:GMC oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MSGEDETEWDYVVVGSGAGGGTLAARLAEAGMRVCVLEAGCDARAHEMSCMPEDYDVPGFHACASENPAMAWNFFVRHYT
DDAQQHRDPKCGPAGVLYPRAGTLGGCTAHNALIFLYPHDADWDHIADVTGDPSWTATRMRSYAKRIEQCRHRPLWNLAR
RFGIDPTLHGWDGWLHTERAMPLEALADDALVRVIIGSMELAARSVPRRVRAWLRLIRWQGDPNSRLWGRRCFHGVCYTP
LTTQRHARHGTRERLLDVAERYPDRLRIELDALATRVLFDAQGNACGVEYLKGRHLYQAHVKPSDGDGERCQVRARREVI
LAGGAFNTPQLLMLSGIGPAEHLQEHGIPVRVDLTGVGRNLQDRYEIGVVNRMSRSWEVLQGAKFVRDDAPYQSWFDSRD
GVYTTNGVATAVIRRSGRRMPVPDIFCMALLERFVGYYPGYSKVFAQNDNVLTWAILKAHTRNRAGVVSLRSADPRDMPD
IDFRYFDGADDPHGDDMRALIGAIRFVRGLAQPLAEQGLIANEELPGVDVQSDEALAAYIRDNAWGHHASCSCPIGARAT
GGVLDSNFCVHGTRRLRVVDASAFPRIPGFFPVSAIYMMAEKAADVLLATAQATPPLPFPIGDRHGLRRAQAPANAAGRT
G

Sequences:

>Translated_641_residues
MSGEDETEWDYVVVGSGAGGGTLAARLAEAGMRVCVLEAGCDARAHEMSCMPEDYDVPGFHACASENPAMAWNFFVRHYT
DDAQQHRDPKCGPAGVLYPRAGTLGGCTAHNALIFLYPHDADWDHIADVTGDPSWTATRMRSYAKRIEQCRHRPLWNLAR
RFGIDPTLHGWDGWLHTERAMPLEALADDALVRVIIGSMELAARSVPRRVRAWLRLIRWQGDPNSRLWGRRCFHGVCYTP
LTTQRHARHGTRERLLDVAERYPDRLRIELDALATRVLFDAQGNACGVEYLKGRHLYQAHVKPSDGDGERCQVRARREVI
LAGGAFNTPQLLMLSGIGPAEHLQEHGIPVRVDLTGVGRNLQDRYEIGVVNRMSRSWEVLQGAKFVRDDAPYQSWFDSRD
GVYTTNGVATAVIRRSGRRMPVPDIFCMALLERFVGYYPGYSKVFAQNDNVLTWAILKAHTRNRAGVVSLRSADPRDMPD
IDFRYFDGADDPHGDDMRALIGAIRFVRGLAQPLAEQGLIANEELPGVDVQSDEALAAYIRDNAWGHHASCSCPIGARAT
GGVLDSNFCVHGTRRLRVVDASAFPRIPGFFPVSAIYMMAEKAADVLLATAQATPPLPFPIGDRHGLRRAQAPANAAGRT
G
>Mature_640_residues
SGEDETEWDYVVVGSGAGGGTLAARLAEAGMRVCVLEAGCDARAHEMSCMPEDYDVPGFHACASENPAMAWNFFVRHYTD
DAQQHRDPKCGPAGVLYPRAGTLGGCTAHNALIFLYPHDADWDHIADVTGDPSWTATRMRSYAKRIEQCRHRPLWNLARR
FGIDPTLHGWDGWLHTERAMPLEALADDALVRVIIGSMELAARSVPRRVRAWLRLIRWQGDPNSRLWGRRCFHGVCYTPL
TTQRHARHGTRERLLDVAERYPDRLRIELDALATRVLFDAQGNACGVEYLKGRHLYQAHVKPSDGDGERCQVRARREVIL
AGGAFNTPQLLMLSGIGPAEHLQEHGIPVRVDLTGVGRNLQDRYEIGVVNRMSRSWEVLQGAKFVRDDAPYQSWFDSRDG
VYTTNGVATAVIRRSGRRMPVPDIFCMALLERFVGYYPGYSKVFAQNDNVLTWAILKAHTRNRAGVVSLRSADPRDMPDI
DFRYFDGADDPHGDDMRALIGAIRFVRGLAQPLAEQGLIANEELPGVDVQSDEALAAYIRDNAWGHHASCSCPIGARATG
GVLDSNFCVHGTRRLRVVDASAFPRIPGFFPVSAIYMMAEKAADVLLATAQATPPLPFPIGDRHGLRRAQAPANAAGRTG

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=348, Percent_Identity=33.0459770114943, Blast_Score=142, Evalue=9e-34,
Organism=Escherichia coli, GI1786503, Length=606, Percent_Identity=25.5775577557756, Blast_Score=130, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17532301, Length=634, Percent_Identity=26.3406940063091, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI45549471, Length=637, Percent_Identity=28.414442700157, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI45551458, Length=637, Percent_Identity=28.414442700157, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24642055, Length=659, Percent_Identity=26.7071320182094, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24642042, Length=633, Percent_Identity=27.4881516587678, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24642059, Length=637, Percent_Identity=27.6295133437991, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24650267, Length=633, Percent_Identity=26.3823064770932, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24642051, Length=638, Percent_Identity=24.6081504702194, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24642039, Length=636, Percent_Identity=26.8867924528302, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24642037, Length=643, Percent_Identity=26.2830482115086, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI18859995, Length=634, Percent_Identity=27.1293375394322, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18859993, Length=638, Percent_Identity=25.8620689655172, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24642048, Length=637, Percent_Identity=24.4897959183673, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17137792, Length=396, Percent_Identity=27.2727272727273, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24645930, Length=394, Percent_Identity=26.1421319796954, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 71021; Mature: 70890

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEDETEWDYVVVGSGAGGGTLAARLAEAGMRVCVLEAGCDARAHEMSCMPEDYDVPGF
CCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHCCCCCCCCCCCCC
HACASENPAMAWNFFVRHYTDDAQQHRDPKCGPAGVLYPRAGTLGGCTAHNALIFLYPHD
CHHCCCCCCEEHHHHHHHHCCHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECC
ADWDHIADVTGDPSWTATRMRSYAKRIEQCRHRPLWNLARRFGIDPTLHGWDGWLHTERA
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCC
MPLEALADDALVRVIIGSMELAARSVPRRVRAWLRLIRWQGDPNSRLWGRRCFHGVCYTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
LTTQRHARHGTRERLLDVAERYPDRLRIELDALATRVLFDAQGNACGVEYLKGRHLYQAH
CCCHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHHHHEEECCCCCCCHHHHCCCCEEEEE
VKPSDGDGERCQVRARREVILAGGAFNTPQLLMLSGIGPAEHLQEHGIPVRVDLTGVGRN
CCCCCCCCCHHHEEECEEEEEECCCCCCCCEEEEECCCHHHHHHHCCCEEEEEEEECCCC
LQDRYEIGVVNRMSRSWEVLQGAKFVRDDAPYQSWFDSRDGVYTTNGVATAVIRRSGRRM
CHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCCCCEEECCHHHHHHHHHCCCCC
PVPDIFCMALLERFVGYYPGYSKVFAQNDNVLTWAILKAHTRNRAGVVSLRSADPRDMPD
CCHHHHHHHHHHHHHHHCCCHHHEEECCCCEEEEEEEEHHCCCCCCEEEECCCCCCCCCC
IDFRYFDGADDPHGDDMRALIGAIRFVRGLAQPLAEQGLIANEELPGVDVQSDEALAAYI
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
RDNAWGHHASCSCPIGARATGGVLDSNFCVHGTRRLRVVDASAFPRIPGFFPVSAIYMMA
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHH
EKAADVLLATAQATPPLPFPIGDRHGLRRAQAPANAAGRTG
HHHHHHEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
SGEDETEWDYVVVGSGAGGGTLAARLAEAGMRVCVLEAGCDARAHEMSCMPEDYDVPGF
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHCCCCCCCCCCCCC
HACASENPAMAWNFFVRHYTDDAQQHRDPKCGPAGVLYPRAGTLGGCTAHNALIFLYPHD
CHHCCCCCCEEHHHHHHHHCCHHHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECC
ADWDHIADVTGDPSWTATRMRSYAKRIEQCRHRPLWNLARRFGIDPTLHGWDGWLHTERA
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEECCCC
MPLEALADDALVRVIIGSMELAARSVPRRVRAWLRLIRWQGDPNSRLWGRRCFHGVCYTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
LTTQRHARHGTRERLLDVAERYPDRLRIELDALATRVLFDAQGNACGVEYLKGRHLYQAH
CCCHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHHHHEEECCCCCCCHHHHCCCCEEEEE
VKPSDGDGERCQVRARREVILAGGAFNTPQLLMLSGIGPAEHLQEHGIPVRVDLTGVGRN
CCCCCCCCCHHHEEECEEEEEECCCCCCCCEEEEECCCHHHHHHHCCCEEEEEEEECCCC
LQDRYEIGVVNRMSRSWEVLQGAKFVRDDAPYQSWFDSRDGVYTTNGVATAVIRRSGRRM
CHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCCCCEEECCHHHHHHHHHCCCCC
PVPDIFCMALLERFVGYYPGYSKVFAQNDNVLTWAILKAHTRNRAGVVSLRSADPRDMPD
CCHHHHHHHHHHHHHHHCCCHHHEEECCCCEEEEEEEEHHCCCCCCEEEECCCCCCCCCC
IDFRYFDGADDPHGDDMRALIGAIRFVRGLAQPLAEQGLIANEELPGVDVQSDEALAAYI
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
RDNAWGHHASCSCPIGARATGGVLDSNFCVHGTRRLRVVDASAFPRIPGFFPVSAIYMMA
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHH
EKAADVLLATAQATPPLPFPIGDRHGLRRAQAPANAAGRTG
HHHHHHEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA