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The map label for this gene is iorA [H]

Identifier: 73541432

GI number: 73541432

Start: 1886076

End: 1886540

Strand: Reverse

Name: iorA [H]

Synonym: Reut_A1743

Alternate gene names: 73541432

Gene position: 1886540-1886076 (Counterclockwise)

Preceding gene: 73541433

Following gene: 73541430

Centisome position: 49.56

GC content: 64.95

Gene sequence:

>465_bases
ATGGCGACCCTGAACGTGAACGACAAGGCCGTCAGCGTTGACGCGGAGCCGGATATGCCGTTGCTATGGATCCTGCGCTG
CGACCTTGCGTTGACAGGAACAAAGTTCGGCTGCGGCGTGGGCATTTGCGGCGCCTGCACGCTGCATGTGGATGGCAAGC
CCGAACTCGCATGCCAGCTGCCGATGTCGAAGTTGCGGCCGGGCGCGAAGATCACGACCATCGAGGGCATGCGGAGCAAG
GAACTCGACGCTGTCCGTGCGGCCTGGCTCGATCTCGATGTGGTCCAGTGCGGCTACTGCCAGAGCGCGCAGATCATGGC
CGCATGCGCGCTGCTCAAGGCCAGGCCGAAGCCTACCGACGCTGACATCGACGCGGCGATGGGCAATATTGTCTGCCGCT
GCGGCACGTATCCACGGATCCGCGCTGCGATCCATCAGGCGGCCGGGCAAGCGCCGCACGGCTGA

Upstream 100 bases:

>100_bases
CACCGCCGATCGCACCGGCCGTGGCCAATGCGCTGTATACGCTGACCGGCCAGCGCTTGCGTTCGTTGCCGCTCAAGCTG
ATCTAGTGAAGGAGACCACC

Downstream 100 bases:

>100_bases
TGTCCCGGGCGGTACCGGGACATCAGAGCGCTCAACCAGGAGCGGATTGGGTGGTTCCAGTCTGGCCGGGCTTGCGCAGC
ATCTTGTCGACTTCGCCGGC

Product: ferredoxin:(2Fe-2S)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MATLNVNDKAVSVDAEPDMPLLWILRCDLALTGTKFGCGVGICGACTLHVDGKPELACQLPMSKLRPGAKITTIEGMRSK
ELDAVRAAWLDLDVVQCGYCQSAQIMAACALLKARPKPTDADIDAAMGNIVCRCGTYPRIRAAIHQAAGQAPHG

Sequences:

>Translated_154_residues
MATLNVNDKAVSVDAEPDMPLLWILRCDLALTGTKFGCGVGICGACTLHVDGKPELACQLPMSKLRPGAKITTIEGMRSK
ELDAVRAAWLDLDVVQCGYCQSAQIMAACALLKARPKPTDADIDAAMGNIVCRCGTYPRIRAAIHQAAGQAPHG
>Mature_153_residues
ATLNVNDKAVSVDAEPDMPLLWILRCDLALTGTKFGCGVGICGACTLHVDGKPELACQLPMSKLRPGAKITTIEGMRSKE
LDAVRAAWLDLDVVQCGYCQSAQIMAACALLKARPKPTDADIDAAMGNIVCRCGTYPRIRAAIHQAAGQAPHG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=40.8536585365854, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI1789232, Length=139, Percent_Identity=37.410071942446, Blast_Score=72, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540638, Length=155, Percent_Identity=36.1290322580645, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566215, Length=160, Percent_Identity=30, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17737937, Length=145, Percent_Identity=35.1724137931034, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16278; Mature: 16147

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
10.4 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
9.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLNVNDKAVSVDAEPDMPLLWILRCDLALTGTKFGCGVGICGACTLHVDGKPELACQL
CEEECCCCCEEEECCCCCCCEEEEEEECEEEECCCCCCCCCCCEEEEEEECCCCCEEEEC
PMSKLRPGAKITTIEGMRSKELDAVRAAWLDLDVVQCGYCQSAQIMAACALLKARPKPTD
CHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCCCC
ADIDAAMGNIVCRCGTYPRIRAAIHQAAGQAPHG
CCHHHHHHHEEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ATLNVNDKAVSVDAEPDMPLLWILRCDLALTGTKFGCGVGICGACTLHVDGKPELACQL
EEECCCCCEEEECCCCCCCEEEEEEECEEEECCCCCCCCCCCEEEEEEECCCCCEEEEC
PMSKLRPGAKITTIEGMRSKELDAVRAAWLDLDVVQCGYCQSAQIMAACALLKARPKPTD
CHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCCCC
ADIDAAMGNIVCRCGTYPRIRAAIHQAAGQAPHG
CCHHHHHHHEEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]