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The map label for this gene is yciR [C]

Identifier: 73541425

GI number: 73541425

Start: 1876363

End: 1878354

Strand: Reverse

Name: yciR [C]

Synonym: Reut_A1736

Alternate gene names: 73541425

Gene position: 1878354-1876363 (Counterclockwise)

Preceding gene: 73541426

Following gene: 73541424

Centisome position: 49.35

GC content: 61.5

Gene sequence:

>1992_bases
GTGCGTTGTGAATGTCAATACCGTGACGGGTTTTGCAGCGCGATTCCGCGAGGCCGTAATAGAATTGGATTCCCGTCAAT
TCACACTCATGGCGGCCAGTCGTGTTTTCGGACCATTAATGCTGTCCTCTTTACCGGCTTTTCATGCGTTAACGCCGACC
CCCGGGGATCGGCACGGTGCAGTCGTCAAACAGGCCAGGCCAACAACCACATGACGTCGTTTACGTATGATGCTGTGCAC
GCAGGCAATGCGCCGGGACCGGTCCGTTCCGGCAGCGTTGCCACAGCGACGACGCTTGCCGGTAACCGGGATGCCTGGGC
GCTGCTGGAAGCCTGGGGTGGGTTGGCACTGCATGTCAGCGAGACCGGGAATATTCTCCAGGCCACCAGTGCTTCCGCGG
ATTTGCTGGCTTTCCCGCGCGAATATCTGCTGGATGCGTCGATCAAGGACATTATTGCCTTCGACGAACGCGAGCGCGCC
GCCCATCTGCTGCAGGCCTGTTTTCGCGATGGCGTGTCCAGACAAGCCGATATCCGTTTTGCCAACGCCATAAACGGCAC
GCGCTGGATCGACCTGCGCATTTGCCGGCATGTCACTGCAGAGGGCAGAGCTTCGCTGCTGCTGTTTGGTGCCGACGTTA
CCAAATGGGCCCAGAAGCTCCATCAATTGACGGAACAGTCGCTGACCGATCCACTGACCGGTGTAGGAAACCGGGCGCTG
ATCCGCAACCGGGTGGAAGCGTATTTCACCGGCGATGCCTCGCAGCGCGGCCGCTTTGCCATTGCGCTGATGGATCTTGA
TGGATTCAAGAAGATCAATGATTCGCTCGGCCATGAGATCGGCGACATCCTGCTCAAGGAGTTGAGCCAGCGCCTGGTGG
CAACCGTGCGCTCTCGCGACACCGTTGCGCGCCTTGGCGGCGATGAATTCGTGATCCTGCTTGACGACGTCAGTTCGGAA
GAGGCCGCGGTGGGGATGCTCGAGCAGATCATGCGTGTCTGCAGGCAGCCGTTCCATCTGGCCGGCTGCCAGGTCCGTGT
GACGACCAGCATCGGGCTGGCGTTTGCGTCGGGCGTGCGCGAGACCGATGCACAGCTGCTGCGGCGGGCCGACCGCGCCA
TGTACGAGGCCAAGGCCCAGGGCAACAACCGCTATTGCCTGTATTCGTCGGAACTCGACCATCGCCTGAACGAGCAATTC
CGCATCGAGCAGGACCTGTTCGAGGCGGTCCTCAACGGCGAACTGTTCCTGCATTACCAGCCGATTTTCAGGGTCGGTCC
GGACACGGTCTGCGCGGTCGAGGCGCTGATGCGGTGGGAACATCCGGCCGGATCCATCTCGCCCGAGGTGTTCGTGCCGC
TGGCCGAAAGTAACGGCCTGATCAATCATCTCGGCGCCTGGGCCATCCGCTGCGCGTGCGCGCAACTGGCTGCCTGGAAG
GCCAACGGTGTCGCACTCGGTTATGTGTCTGTCAACGTGTCGCCGGTGCAGTTCAGGCATCCGGGCTTTATCGACAGCGT
ACGCACTGCCATCCGCGATACCGGGATCGACCCGCACCGGCTGGTGCTGGAGATCACCGAAGGCGCGCTGATGACCGACC
CCAAGGCTGCCGGGGACCTGCTGACCGAACTCGGAGCACTCGGAATCCGTTTCGCAGTCGATGACTTTGGCACGGGCTAT
TCGAGCTTGTCTTATCTGCGCCGTTTCCCCTTGTCCGCCCTGAAAATCGATCGCAGCTTTGTCGCCGATATGGTCGATTC
TCCGCACGCCCGGACCATCGTTTCGGCGGTGCTGTCGCTCGCACGTGAACTCGGGCTCGTGGCGATTGCGGAAGGCGTCG
AGACCGAAGCGCAATGCGATCTGCTGGCCGCACAGCGCTGTGAGTTGGCACAAGGCTGGCGCTTTGCCAAGGCAATGGCG
CCCAATGATTTCGAGGATGCTGTCCGCACGGGCAGGTTCCGGCTTGACGCCGCGGACGCATTGGCTGGCTGA

Upstream 100 bases:

>100_bases
GACGTACCGAAATCTTTACCCTTGTCCGCGGCGCGCGATATCCACGTGCTTCCATAGATCAAGGGTTTTGTCTACCCCAC
ACCTTAGTGAAACGGGAAGA

Downstream 100 bases:

>100_bases
TTGAGACTATGTCAAAGAAACAGTTCCTCGATCAGCTTTGGGCCAGGATGGCCCAGAAAGGCGATTTCCCGACGCTCCAG
TATTGCATCGACAACGTCTT

Product: diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MRCECQYRDGFCSAIPRGRNRIGFPSIHTHGGQSCFRTINAVLFTGFSCVNADPRGSARCSRQTGQANNHMTSFTYDAVH
AGNAPGPVRSGSVATATTLAGNRDAWALLEAWGGLALHVSETGNILQATSASADLLAFPREYLLDASIKDIIAFDERERA
AHLLQACFRDGVSRQADIRFANAINGTRWIDLRICRHVTAEGRASLLLFGADVTKWAQKLHQLTEQSLTDPLTGVGNRAL
IRNRVEAYFTGDASQRGRFAIALMDLDGFKKINDSLGHEIGDILLKELSQRLVATVRSRDTVARLGGDEFVILLDDVSSE
EAAVGMLEQIMRVCRQPFHLAGCQVRVTTSIGLAFASGVRETDAQLLRRADRAMYEAKAQGNNRYCLYSSELDHRLNEQF
RIEQDLFEAVLNGELFLHYQPIFRVGPDTVCAVEALMRWEHPAGSISPEVFVPLAESNGLINHLGAWAIRCACAQLAAWK
ANGVALGYVSVNVSPVQFRHPGFIDSVRTAIRDTGIDPHRLVLEITEGALMTDPKAAGDLLTELGALGIRFAVDDFGTGY
SSLSYLRRFPLSALKIDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETEAQCDLLAAQRCELAQGWRFAKAMA
PNDFEDAVRTGRFRLDAADALAG

Sequences:

>Translated_663_residues
MRCECQYRDGFCSAIPRGRNRIGFPSIHTHGGQSCFRTINAVLFTGFSCVNADPRGSARCSRQTGQANNHMTSFTYDAVH
AGNAPGPVRSGSVATATTLAGNRDAWALLEAWGGLALHVSETGNILQATSASADLLAFPREYLLDASIKDIIAFDERERA
AHLLQACFRDGVSRQADIRFANAINGTRWIDLRICRHVTAEGRASLLLFGADVTKWAQKLHQLTEQSLTDPLTGVGNRAL
IRNRVEAYFTGDASQRGRFAIALMDLDGFKKINDSLGHEIGDILLKELSQRLVATVRSRDTVARLGGDEFVILLDDVSSE
EAAVGMLEQIMRVCRQPFHLAGCQVRVTTSIGLAFASGVRETDAQLLRRADRAMYEAKAQGNNRYCLYSSELDHRLNEQF
RIEQDLFEAVLNGELFLHYQPIFRVGPDTVCAVEALMRWEHPAGSISPEVFVPLAESNGLINHLGAWAIRCACAQLAAWK
ANGVALGYVSVNVSPVQFRHPGFIDSVRTAIRDTGIDPHRLVLEITEGALMTDPKAAGDLLTELGALGIRFAVDDFGTGY
SSLSYLRRFPLSALKIDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETEAQCDLLAAQRCELAQGWRFAKAMA
PNDFEDAVRTGRFRLDAADALAG
>Mature_663_residues
MRCECQYRDGFCSAIPRGRNRIGFPSIHTHGGQSCFRTINAVLFTGFSCVNADPRGSARCSRQTGQANNHMTSFTYDAVH
AGNAPGPVRSGSVATATTLAGNRDAWALLEAWGGLALHVSETGNILQATSASADLLAFPREYLLDASIKDIIAFDERERA
AHLLQACFRDGVSRQADIRFANAINGTRWIDLRICRHVTAEGRASLLLFGADVTKWAQKLHQLTEQSLTDPLTGVGNRAL
IRNRVEAYFTGDASQRGRFAIALMDLDGFKKINDSLGHEIGDILLKELSQRLVATVRSRDTVARLGGDEFVILLDDVSSE
EAAVGMLEQIMRVCRQPFHLAGCQVRVTTSIGLAFASGVRETDAQLLRRADRAMYEAKAQGNNRYCLYSSELDHRLNEQF
RIEQDLFEAVLNGELFLHYQPIFRVGPDTVCAVEALMRWEHPAGSISPEVFVPLAESNGLINHLGAWAIRCACAQLAAWK
ANGVALGYVSVNVSPVQFRHPGFIDSVRTAIRDTGIDPHRLVLEITEGALMTDPKAAGDLLTELGALGIRFAVDDFGTGY
SSLSYLRRFPLSALKIDRSFVADMVDSPHARTIVSAVLSLARELGLVAIAEGVETEAQCDLLAAQRCELAQGWRFAKAMA
PNDFEDAVRTGRFRLDAADALAG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=441, Percent_Identity=32.8798185941043, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI87081921, Length=426, Percent_Identity=31.2206572769953, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI226510982, Length=427, Percent_Identity=29.03981264637, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1790496, Length=243, Percent_Identity=35.3909465020576, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=32.5, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI87081845, Length=266, Percent_Identity=35.3383458646617, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=35.0210970464135, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788502, Length=256, Percent_Identity=31.640625, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787055, Length=257, Percent_Identity=33.4630350194552, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081980, Length=232, Percent_Identity=31.8965517241379, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788381, Length=202, Percent_Identity=34.1584158415842, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1788849, Length=246, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788956, Length=175, Percent_Identity=36, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=34.1772151898734, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082096, Length=414, Percent_Identity=23.4299516908213, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787816, Length=186, Percent_Identity=32.258064516129, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=31.5508021390374, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081977, Length=196, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI145693134, Length=136, Percent_Identity=38.2352941176471, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=34.3915343915344, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788085, Length=210, Percent_Identity=27.6190476190476, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=30.9090909090909, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=33.75, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=167, Percent_Identity=29.3413173652695, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787056, Length=177, Percent_Identity=27.683615819209, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787410, Length=166, Percent_Identity=27.1084337349398, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 72412; Mature: 72412

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCECQYRDGFCSAIPRGRNRIGFPSIHTHGGQSCFRTINAVLFTGFSCVNADPRGSARC
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCHH
SRQTGQANNHMTSFTYDAVHAGNAPGPVRSGSVATATTLAGNRDAWALLEAWGGLALHVS
HHCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCEEEEEE
ETGNILQATSASADLLAFPREYLLDASIKDIIAFDERERAAHLLQACFRDGVSRQADIRF
CCCCEEEECCCCCHHHHCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEE
ANAINGTRWIDLRICRHVTAEGRASLLLFGADVTKWAQKLHQLTEQSLTDPLTGVGNRAL
ECCCCCCEEEEHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHCCCCHHH
IRNRVEAYFTGDASQRGRFAIALMDLDGFKKINDSLGHEIGDILLKELSQRLVATVRSRD
HHHCHHEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TVARLGGDEFVILLDDVSSEEAAVGMLEQIMRVCRQPFHLAGCQVRVTTSIGLAFASGVR
HHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEEEHHHHHHHCCCC
ETDAQLLRRADRAMYEAKAQGNNRYCLYSSELDHRLNEQFRIEQDLFEAVLNGELFLHYQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
PIFRVGPDTVCAVEALMRWEHPAGSISPEVFVPLAESNGLINHLGAWAIRCACAQLAAWK
CHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
ANGVALGYVSVNVSPVQFRHPGFIDSVRTAIRDTGIDPHRLVLEITEGALMTDPKAAGDL
CCCEEEEEEEEECCEEEECCCCHHHHHHHHHHHCCCCHHHEEEEEECCCEECCCHHHHHH
LTELGALGIRFAVDDFGTGYSSLSYLRRFPLSALKIDRSFVADMVDSPHARTIVSAVLSL
HHHHHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARELGLVAIAEGVETEAQCDLLAAQRCELAQGWRFAKAMAPNDFEDAVRTGRFRLDAADA
HHHCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCEEEEHHHH
LAG
CCC
>Mature Secondary Structure
MRCECQYRDGFCSAIPRGRNRIGFPSIHTHGGQSCFRTINAVLFTGFSCVNADPRGSARC
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCHH
SRQTGQANNHMTSFTYDAVHAGNAPGPVRSGSVATATTLAGNRDAWALLEAWGGLALHVS
HHCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCEEEEEE
ETGNILQATSASADLLAFPREYLLDASIKDIIAFDERERAAHLLQACFRDGVSRQADIRF
CCCCEEEECCCCCHHHHCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEE
ANAINGTRWIDLRICRHVTAEGRASLLLFGADVTKWAQKLHQLTEQSLTDPLTGVGNRAL
ECCCCCCEEEEHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHCCCCHHH
IRNRVEAYFTGDASQRGRFAIALMDLDGFKKINDSLGHEIGDILLKELSQRLVATVRSRD
HHHCHHEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TVARLGGDEFVILLDDVSSEEAAVGMLEQIMRVCRQPFHLAGCQVRVTTSIGLAFASGVR
HHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEEEHHHHHHHCCCC
ETDAQLLRRADRAMYEAKAQGNNRYCLYSSELDHRLNEQFRIEQDLFEAVLNGELFLHYQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
PIFRVGPDTVCAVEALMRWEHPAGSISPEVFVPLAESNGLINHLGAWAIRCACAQLAAWK
CHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
ANGVALGYVSVNVSPVQFRHPGFIDSVRTAIRDTGIDPHRLVLEITEGALMTDPKAAGDL
CCCEEEEEEEEECCEEEECCCCHHHHHHHHHHHCCCCHHHEEEEEECCCEECCCHHHHHH
LTELGALGIRFAVDDFGTGYSSLSYLRRFPLSALKIDRSFVADMVDSPHARTIVSAVLSL
HHHHHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARELGLVAIAEGVETEAQCDLLAAQRCELAQGWRFAKAMAPNDFEDAVRTGRFRLDAADA
HHHCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCEEEEHHHH
LAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]