Click here to switch to the map view.

The map label for this gene is xylR [H]

Identifier: 73541387

GI number: 73541387

Start: 1832996

End: 1834618

Strand: Reverse

Name: xylR [H]

Synonym: Reut_A1698

Alternate gene names: 73541387

Gene position: 1834618-1832996 (Counterclockwise)

Preceding gene: 73541396

Following gene: 73541377

Centisome position: 48.2

GC content: 65.74

Gene sequence:

>1623_bases
ATGACCGCGCCCCCCAAGCAGCCGCCGTTCGACCTGGCTTCGCTGCTGACGATCGACCCCAAGGCCGCACAGATCCGGCT
GGGCGATTCCCGCATGGTGCTGATGCACACGGAGGCCCTGAGCTACTTGCGCAAGGAAATCCTCGACACGCTTGGCCTGG
AGCGCGGCAAGGGCCTGCTGATCCGCATGGGCTACGCGCAAGGCATGCGCGATGCCGAGATGGTCAAGCGCGAGCGCAAG
GAAGAACTCGAGCATTCGCCGAACGACGCCTTCCTGCTGGGCCCGCAGCTCCACATGCTCGAAGGTGTGACGCGGGTCGA
CCCCGTGCGCCTGGAGATCAACCGCGACACCGGCCACTTCTACGGCGAATTCCTCTGGCAGGATTCATGGGAAGGCGAAG
CGCCCTTCAACGAGTCGCTGAGCCGGGAGGAAGGCGGCTGCTGGGTGCAGCTCGGCTATGCGTCCGGCTACAGCAGCACG
TTCATGGACCGCCTCGTCATCTACAAGGAAACCGAATGCCAGCGGCGGCTCGACGCACTGTGCCGCATCGTCGGCAAGCC
GGCCGAGGAGTGGAACGATCCCGACTACCTGAAGTACTTCGAGCCCGATTCCGTCATCAGCGATCTGCTCACCCTGCAGC
AGGAAGTCAGCACGCTGCGCGAAACGCTGTGCGGCGCCAACCAGGGCAACCTGATCGGCCAGTCCCCTGCTTTCCGCGAA
GCGTTTGGTCTGCTGTCCGCCGCTGCTGACAGCCACATCACCGTGCTGCTGACCGGCGAAACCGGCGCCGGCAAGGAGAT
GTTCGCGCGCTGGCTGCATGACCACGGCCCGCGCAGCGAGCAACCGTTCATCGCCGTGAACTGCGCGGCGATCCCGCACG
AGCTGATCGAGTCCGAGCTGTTCGGCGTGGAGAAAGGCGCGTACACCGGCGCGCAGCAGTCGCGCCCCGGCCGCTTCGAG
CGCGCGCACGGCGGCACGCTGTTCCTCGACGAGATCGGCGACCTGCCGCTCTCGGCGCAGGTCAAGCTGCTGCGGGTGCT
GCAGAATGCAGAGGTCGAGCGGCTGGGCGGTGTCGAGACACGCAAGATCGATGTGCGGCTGATTGCAGCCACCAACGTCA
ACCTGGCGCAGGCGATCCGGCAGGGGCAGTTCCGCGCGGACCTGTTCTACCGTATCAGCACGTATCCTGTCGCCATCCCT
GCCCTGCGCGAGCGCCGCGACGATATTCCGGAGCTCGCGCAAGCCTTCATCCAGCGCTTCAACGCGCGCTACCAGAAGCA
GGTACGCGGACTGAGCCAGCGGGCGCGTGATGCGCTGATGCAGTACCAGTGGCCCGGCAATATCCGCGAACTCGAAAACA
TGATCGAGCGCGGCGTGCTGCTGGCGCCCGCTGCCGGCCTGATCGATACGTCCCACTTGTTCGCGAGCCAGCAGGCCGCT
GTCGAGGCGCCCGAAGATGCCGATGCGCTGATCCAGAAATTGCTGGATCAGCAGGTGTCGTTGCCGCAGATCGAGGCGCG
GCTGATGCAGCTTGCGATCGACACGACGCGCGGCAACCTGTCGTCGGCGGCGCGTATGCTGGGCATCACGCGGCCGCAGC
TCGCGTATCGGCTGAAGAAGTAG

Upstream 100 bases:

>100_bases
GTTTGCGTAGGCCCCGAACGCGCGTGTTAGGCTACGGAAAACCGAGGCCAGGACGCTCCCCTCCGGATCGATTCGCGCCC
GCAGGCATTCTGGAGATGAG

Downstream 100 bases:

>100_bases
TGGCGGAGCTGTTTGCCTATTCGTAATCGAACGTGAACGTCGCTGCGCTGGTCACCGTACCGGCCGTCACAGGCAAGCCG
TTGTTCAGCCTGGTGTAGCG

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MTAPPKQPPFDLASLLTIDPKAAQIRLGDSRMVLMHTEALSYLRKEILDTLGLERGKGLLIRMGYAQGMRDAEMVKRERK
EELEHSPNDAFLLGPQLHMLEGVTRVDPVRLEINRDTGHFYGEFLWQDSWEGEAPFNESLSREEGGCWVQLGYASGYSST
FMDRLVIYKETECQRRLDALCRIVGKPAEEWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
AFGLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRSEQPFIAVNCAAIPHELIESELFGVEKGAYTGAQQSRPGRFE
RAHGGTLFLDEIGDLPLSAQVKLLRVLQNAEVERLGGVETRKIDVRLIAATNVNLAQAIRQGQFRADLFYRISTYPVAIP
ALRERRDDIPELAQAFIQRFNARYQKQVRGLSQRARDALMQYQWPGNIRELENMIERGVLLAPAAGLIDTSHLFASQQAA
VEAPEDADALIQKLLDQQVSLPQIEARLMQLAIDTTRGNLSSAARMLGITRPQLAYRLKK

Sequences:

>Translated_540_residues
MTAPPKQPPFDLASLLTIDPKAAQIRLGDSRMVLMHTEALSYLRKEILDTLGLERGKGLLIRMGYAQGMRDAEMVKRERK
EELEHSPNDAFLLGPQLHMLEGVTRVDPVRLEINRDTGHFYGEFLWQDSWEGEAPFNESLSREEGGCWVQLGYASGYSST
FMDRLVIYKETECQRRLDALCRIVGKPAEEWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
AFGLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRSEQPFIAVNCAAIPHELIESELFGVEKGAYTGAQQSRPGRFE
RAHGGTLFLDEIGDLPLSAQVKLLRVLQNAEVERLGGVETRKIDVRLIAATNVNLAQAIRQGQFRADLFYRISTYPVAIP
ALRERRDDIPELAQAFIQRFNARYQKQVRGLSQRARDALMQYQWPGNIRELENMIERGVLLAPAAGLIDTSHLFASQQAA
VEAPEDADALIQKLLDQQVSLPQIEARLMQLAIDTTRGNLSSAARMLGITRPQLAYRLKK
>Mature_539_residues
TAPPKQPPFDLASLLTIDPKAAQIRLGDSRMVLMHTEALSYLRKEILDTLGLERGKGLLIRMGYAQGMRDAEMVKRERKE
ELEHSPNDAFLLGPQLHMLEGVTRVDPVRLEINRDTGHFYGEFLWQDSWEGEAPFNESLSREEGGCWVQLGYASGYSSTF
MDRLVIYKETECQRRLDALCRIVGKPAEEWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFREA
FGLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRSEQPFIAVNCAAIPHELIESELFGVEKGAYTGAQQSRPGRFER
AHGGTLFLDEIGDLPLSAQVKLLRVLQNAEVERLGGVETRKIDVRLIAATNVNLAQAIRQGQFRADLFYRISTYPVAIPA
LRERRDDIPELAQAFIQRFNARYQKQVRGLSQRARDALMQYQWPGNIRELENMIERGVLLAPAAGLIDTSHLFASQQAAV
EAPEDADALIQKLLDQQVSLPQIEARLMQLAIDTTRGNLSSAARMLGITRPQLAYRLKK

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=315, Percent_Identity=44.4444444444444, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1788550, Length=334, Percent_Identity=41.6167664670659, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI87082117, Length=253, Percent_Identity=51.3833992094862, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790299, Length=366, Percent_Identity=40.4371584699454, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1788905, Length=298, Percent_Identity=42.2818791946309, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1789087, Length=262, Percent_Identity=45.0381679389313, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=40.6832298136646, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI87081872, Length=326, Percent_Identity=41.1042944785276, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1786524, Length=324, Percent_Identity=40.4320987654321, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1789233, Length=244, Percent_Identity=44.2622950819672, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787583, Length=314, Percent_Identity=32.8025477707006, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI87081858, Length=362, Percent_Identity=30.1104972375691, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789828, Length=226, Percent_Identity=35.8407079646018, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 60554; Mature: 60423

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPPKQPPFDLASLLTIDPKAAQIRLGDSRMVLMHTEALSYLRKEILDTLGLERGKGLL
CCCCCCCCCCCHHHHEEECCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCEE
IRMGYAQGMRDAEMVKRERKEELEHSPNDAFLLGPQLHMLEGVTRVDPVRLEINRDTGHF
EEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCCCCEEEEEECCCCCH
YGEFLWQDSWEGEAPFNESLSREEGGCWVQLGYASGYSSTFMDRLVIYKETECQRRLDAL
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHEECHHHHHHHHHH
CRIVGKPAEEWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
HHHHCCCHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AFGLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRSEQPFIAVNCAAIPHELIESEL
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHCCHHHHHHHH
FGVEKGAYTGAQQSRPGRFERAHGGTLFLDEIGDLPLSAQVKLLRVLQNAEVERLGGVET
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCE
RKIDVRLIAATNVNLAQAIRQGQFRADLFYRISTYPVAIPALRERRDDIPELAQAFIQRF
EEEEEEEEEECCCHHHHHHHCCCCCEEHEEEEECCCEEHHHHHHHCCCHHHHHHHHHHHH
NARYQKQVRGLSQRARDALMQYQWPGNIRELENMIERGVLLAPAAGLIDTSHLFASQQAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
VEAPEDADALIQKLLDQQVSLPQIEARLMQLAIDTTRGNLSSAARMLGITRPQLAYRLKK
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
TAPPKQPPFDLASLLTIDPKAAQIRLGDSRMVLMHTEALSYLRKEILDTLGLERGKGLL
CCCCCCCCCCHHHHEEECCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCEE
IRMGYAQGMRDAEMVKRERKEELEHSPNDAFLLGPQLHMLEGVTRVDPVRLEINRDTGHF
EEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCCCCEEEEEECCCCCH
YGEFLWQDSWEGEAPFNESLSREEGGCWVQLGYASGYSSTFMDRLVIYKETECQRRLDAL
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHEECHHHHHHHHHH
CRIVGKPAEEWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
HHHHCCCHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AFGLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRSEQPFIAVNCAAIPHELIESEL
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHCCHHHHHHHH
FGVEKGAYTGAQQSRPGRFERAHGGTLFLDEIGDLPLSAQVKLLRVLQNAEVERLGGVET
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCE
RKIDVRLIAATNVNLAQAIRQGQFRADLFYRISTYPVAIPALRERRDDIPELAQAFIQRF
EEEEEEEEEECCCHHHHHHHCCCCCEEHEEEEECCCEEHHHHHHHCCCHHHHHHHHHHHH
NARYQKQVRGLSQRARDALMQYQWPGNIRELENMIERGVLLAPAAGLIDTSHLFASQQAA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
VEAPEDADALIQKLLDQQVSLPQIEARLMQLAIDTTRGNLSSAARMLGITRPQLAYRLKK
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]