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The map label for this gene is catR [H]

Identifier: 73541377

GI number: 73541377

Start: 1822311

End: 1823192

Strand: Reverse

Name: catR [H]

Synonym: Reut_A1688

Alternate gene names: 73541377

Gene position: 1823192-1822311 (Counterclockwise)

Preceding gene: 73541387

Following gene: 73541366

Centisome position: 47.9

GC content: 64.85

Gene sequence:

>882_bases
ATGGAACTCCGACACCTGCGATATTTCCAGGTTGTGGCCCAGGAACTCAATGTCACGCGTGCCGCAGAGCGGCTGCATAT
GGCGCAACCGCCGCTTTCACGCCAGATCCGGCAGTTGGAGGATGAAGTCGGCGTGACCTTGTTCGATCGCGTGGGACGCG
GACTGCGGCTGACGGAGGCGGGCCGTTTCCTGCTGGAACAAACCACGCAACTGACGCAGCGGCTTGAGGAAACCATCGAA
AGCACCCGCCGCATCGGCCGGCAGGACAAGCGCTGGTTCGGCATCGGCTTCGTGCCGTCGGTGCTGTATGGGGTGTTGCC
GGAACTGATTCGCGAACTGCGCGGCTCGGAACAGCAGGTAGAAGTCGGGCTGGCCGAGATGATTACCGTCGAGCAGGTCG
AGGCACTGAAATCCGGCCGCATCGACCTGGGCTTCGGCCGCATTGCGATCAATGACCCTGCCATCCGCCAGGAGGTGGTA
ATGGCAGAACCGCTGGTGGCAGCGCTGCCGGCAAGCCAGCCGGTACCGGCGCTGGACGCGCTGACGCCGCAGGGGCTGGC
CACGCGCCCGTTCATTCTCTACCCGGCGCGGCCACGGCCGAGCTATGCCGACCACCTGCTGTCGCTGTTCCGCGCGCAGG
GTCTGCAACTGCGTGTGGCGCAGGAAGCCAACGAACTGCAGACCGCGCTGGGGCTGGTGGCAGCCGGCGTCGGCATTACG
CTGGTGCCGGCGTCGATACAACGCCTGCATCGCGATGATGTCCGCTACTGCCCGATCGATGCGCCGGGGTTCGTGTCCCC
TGTCATCATGAGCTATCGGGTTGGTGACAGCTCTCAGTTCCTGGCCCAGGCGGTAGCCTGGGTCATGCGTCAAGGGCAGT
AG

Upstream 100 bases:

>100_bases
CCTTTGCGCTGCGGAGAAGGATTGTCGACGAAGTATGAATCTTGACGCGAGTCACGTCCAAGACCGATGATGTCTCAATC
AATACCCTACAGGTATGCCA

Downstream 100 bases:

>100_bases
GGATTGACTGGTCCAGAATCGGGGGAATCAGGCCTGTGAGCGGCGCTGGCGCACCAGGCGGTTCGCTACGCTGATCACAG
CCTGCACTGACGCTTCCACG

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: CatBC operon transcriptional activator [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MELRHLRYFQVVAQELNVTRAAERLHMAQPPLSRQIRQLEDEVGVTLFDRVGRGLRLTEAGRFLLEQTTQLTQRLEETIE
STRRIGRQDKRWFGIGFVPSVLYGVLPELIRELRGSEQQVEVGLAEMITVEQVEALKSGRIDLGFGRIAINDPAIRQEVV
MAEPLVAALPASQPVPALDALTPQGLATRPFILYPARPRPSYADHLLSLFRAQGLQLRVAQEANELQTALGLVAAGVGIT
LVPASIQRLHRDDVRYCPIDAPGFVSPVIMSYRVGDSSQFLAQAVAWVMRQGQ

Sequences:

>Translated_293_residues
MELRHLRYFQVVAQELNVTRAAERLHMAQPPLSRQIRQLEDEVGVTLFDRVGRGLRLTEAGRFLLEQTTQLTQRLEETIE
STRRIGRQDKRWFGIGFVPSVLYGVLPELIRELRGSEQQVEVGLAEMITVEQVEALKSGRIDLGFGRIAINDPAIRQEVV
MAEPLVAALPASQPVPALDALTPQGLATRPFILYPARPRPSYADHLLSLFRAQGLQLRVAQEANELQTALGLVAAGVGIT
LVPASIQRLHRDDVRYCPIDAPGFVSPVIMSYRVGDSSQFLAQAVAWVMRQGQ
>Mature_293_residues
MELRHLRYFQVVAQELNVTRAAERLHMAQPPLSRQIRQLEDEVGVTLFDRVGRGLRLTEAGRFLLEQTTQLTQRLEETIE
STRRIGRQDKRWFGIGFVPSVLYGVLPELIRELRGSEQQVEVGLAEMITVEQVEALKSGRIDLGFGRIAINDPAIRQEVV
MAEPLVAALPASQPVPALDALTPQGLATRPFILYPARPRPSYADHLLSLFRAQGLQLRVAQEANELQTALGLVAAGVGIT
LVPASIQRLHRDDVRYCPIDAPGFVSPVIMSYRVGDSSQFLAQAVAWVMRQGQ

Specific function: Positive regulator of the catBC operon that degrades catechol to acetyl-CoA. CatR binds in trans to the catR-catBC promoter-control region in the presence or absence of inducer but only activates the catBC operon in the presence of the inducer, cis-cis-mu

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=288, Percent_Identity=33.6805555555556, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787879, Length=273, Percent_Identity=32.6007326007326, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI2367136, Length=260, Percent_Identity=30, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790399, Length=277, Percent_Identity=28.5198555956679, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI145693105, Length=270, Percent_Identity=26.2962962962963, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=27.8225806451613, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=27.3092369477912, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787806, Length=253, Percent_Identity=28.0632411067194, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081904, Length=221, Percent_Identity=27.1493212669683, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=24.7933884297521, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789506, Length=246, Percent_Identity=21.9512195121951, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=23.6, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082132, Length=244, Percent_Identity=24.5901639344262, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082184, Length=146, Percent_Identity=29.4520547945205, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=244, Percent_Identity=25, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788481, Length=193, Percent_Identity=28.4974093264249, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32632; Mature: 32632

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLRYFQVVAQELNVTRAAERLHMAQPPLSRQIRQLEDEVGVTLFDRVGRGLRLTEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHCCCCCEEHHH
GRFLLEQTTQLTQRLEETIESTRRIGRQDKRWFGIGFVPSVLYGVLPELIRELRGSEQQV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHH
EVGLAEMITVEQVEALKSGRIDLGFGRIAINDPAIRQEVVMAEPLVAALPASQPVPALDA
HHHHHHHHHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHC
LTPQGLATRPFILYPARPRPSYADHLLSLFRAQGLQLRVAQEANELQTALGLVAAGVGIT
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCE
LVPASIQRLHRDDVRYCPIDAPGFVSPVIMSYRVGDSSQFLAQAVAWVMRQGQ
EEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELRHLRYFQVVAQELNVTRAAERLHMAQPPLSRQIRQLEDEVGVTLFDRVGRGLRLTEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHCCCCCEEHHH
GRFLLEQTTQLTQRLEETIESTRRIGRQDKRWFGIGFVPSVLYGVLPELIRELRGSEQQV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHH
EVGLAEMITVEQVEALKSGRIDLGFGRIAINDPAIRQEVVMAEPLVAALPASQPVPALDA
HHHHHHHHHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHC
LTPQGLATRPFILYPARPRPSYADHLLSLFRAQGLQLRVAQEANELQTALGLVAAGVGIT
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCE
LVPASIQRLHRDDVRYCPIDAPGFVSPVIMSYRVGDSSQFLAQAVAWVMRQGQ
EEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1688844 [H]