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The map label for this gene is paaG [C]

Identifier: 73541250

GI number: 73541250

Start: 1680671

End: 1681558

Strand: Direct

Name: paaG [C]

Synonym: Reut_A1560

Alternate gene names: 73541250

Gene position: 1680671-1681558 (Clockwise)

Preceding gene: 73541249

Following gene: 73541251

Centisome position: 44.15

GC content: 64.41

Gene sequence:

>888_bases
ATGACAACGCCAGCCATCGAGCCCATCGCACTCGGCCCGAATGCCGAAGTGCTCTACCACGTGGCGGACGGCATTGCCAC
CGTCACCATGAACCGTCCGCAGTACCACAACGCGCAGAACTCGAAGATGACGTATGCGCTGGACGAGGCCTATCGCCGCG
CCGCGTCGGATGACGCGGTCAAGGTGATCGTGCTGCGCGGTGCAGGCAAGCATTTTTCCGCCGGCCACGATATCGGCACG
CCTGGGCGCGACATCAACGAATCGTTCGATCGCACGTCGCTCTGGTATGACCACGTCAACAAGCCTGGCGGCGAGTTCCT
CTATGCACGCGAGCAGGAGGTGTATCTGGGCATGTGCCGTCGCTGGCGCGAACTGCCCAAGCCGACCATTGCGATGGTGC
ACGGTGCCTGCATTGCCGGCGGGCTGATGCTCGCCTGGGTGTGCGACCTGATCGTGGCGTCCGATGACGCATTCTTTGCC
GACCCGGTCGTGCGCATGGGCATTCCCGGCGTGGAGTACTTCGCGCATCCCTATGAACTGCACCCGCGCATCGCCAAGGA
ATTCCTGTTCCTGGGCGAGCGCATGAGCGCGGAACGCGCCGAGCGCATGGGCATGGTCAACCGCGTGGTGCCGCGCGATG
CGCTGGAGGACGCCGTCTACGGCATGGCCGCGAAGGTCGCGCAGATGCCGAGGCTCGGGCTGACCCTGACCAAGCAGGCG
GTCAACCATGTGGAAGACCTGCAAGGCAAGCGCACAGCAATGGACGCTGTCTTCGCTTGGCACCACTTCGCGCATGCACA
CAACGAACTGATCAGCGGCGACAAGCTCGGCGGCTACGACGCGCGCGCCATGGCGGCATCGCAACGAACCGGGGAGGGCA
AGGCATGA

Upstream 100 bases:

>100_bases
CCCACGCCGGAAGAGCTGCGCCTCATCGCGCAGCTCGACCCGCACAACCTGCGCGCGACCATCGTGCGCGGCAACCCTTC
CGGACGCGCGTGAGGCAACC

Downstream 100 bases:

>100_bases
GCGCGTCCGGCCTGCATACGGTGCTGTGCGACCTGCTTGGCTGCCGCTATCCCATTGTCCAGACGGCAATGGGTTGGGTG
GCCGATGCGAAGCTGGTTGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTTPAIEPIALGPNAEVLYHVADGIATVTMNRPQYHNAQNSKMTYALDEAYRRAASDDAVKVIVLRGAGKHFSAGHDIGT
PGRDINESFDRTSLWYDHVNKPGGEFLYAREQEVYLGMCRRWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFA
DPVVRMGIPGVEYFAHPYELHPRIAKEFLFLGERMSAERAERMGMVNRVVPRDALEDAVYGMAAKVAQMPRLGLTLTKQA
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELISGDKLGGYDARAMAASQRTGEGKA

Sequences:

>Translated_295_residues
MTTPAIEPIALGPNAEVLYHVADGIATVTMNRPQYHNAQNSKMTYALDEAYRRAASDDAVKVIVLRGAGKHFSAGHDIGT
PGRDINESFDRTSLWYDHVNKPGGEFLYAREQEVYLGMCRRWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFA
DPVVRMGIPGVEYFAHPYELHPRIAKEFLFLGERMSAERAERMGMVNRVVPRDALEDAVYGMAAKVAQMPRLGLTLTKQA
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELISGDKLGGYDARAMAASQRTGEGKA
>Mature_294_residues
TTPAIEPIALGPNAEVLYHVADGIATVTMNRPQYHNAQNSKMTYALDEAYRRAASDDAVKVIVLRGAGKHFSAGHDIGTP
GRDINESFDRTSLWYDHVNKPGGEFLYAREQEVYLGMCRRWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFAD
PVVRMGIPGVEYFAHPYELHPRIAKEFLFLGERMSAERAERMGMVNRVVPRDALEDAVYGMAAKVAQMPRLGLTLTKQAV
NHVEDLQGKRTAMDAVFAWHHFAHAHNELISGDKLGGYDARAMAASQRTGEGKA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=226, Percent_Identity=28.7610619469027, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI260275230, Length=226, Percent_Identity=28.7610619469027, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI31542718, Length=225, Percent_Identity=31.1111111111111, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI260274832, Length=226, Percent_Identity=28.7610619469027, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=28.2258064516129, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI70995211, Length=191, Percent_Identity=31.413612565445, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1787660, Length=242, Percent_Identity=30.9917355371901, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788597, Length=232, Percent_Identity=33.1896551724138, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787659, Length=238, Percent_Identity=26.0504201680672, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI221142681, Length=233, Percent_Identity=32.1888412017167, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87082183, Length=215, Percent_Identity=27.4418604651163, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=224, Percent_Identity=28.125, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=276, Percent_Identity=24.2753623188406, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=253, Percent_Identity=25.296442687747, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357171, Length=240, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24653139, Length=242, Percent_Identity=29.7520661157025, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24650670, Length=233, Percent_Identity=30.9012875536481, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19920382, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654903, Length=244, Percent_Identity=21.7213114754098, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 32581; Mature: 32449

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPAIEPIALGPNAEVLYHVADGIATVTMNRPQYHNAQNSKMTYALDEAYRRAASDDAV
CCCCCCCCEEECCCCCEEEEECCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHCCCCCE
KVIVLRGAGKHFSAGHDIGTPGRDINESFDRTSLWYDHVNKPGGEFLYAREQEVYLGMCR
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHH
RWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFADPVVRMGIPGVEYFAHPYEL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCHHHHCCCHHC
HPRIAKEFLFLGERMSAERAERMGMVNRVVPRDALEDAVYGMAAKVAQMPRLGLTLTKQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELISGDKLGGYDARAMAASQRTGEGKA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTPAIEPIALGPNAEVLYHVADGIATVTMNRPQYHNAQNSKMTYALDEAYRRAASDDAV
CCCCCCCEEECCCCCEEEEECCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHCCCCCE
KVIVLRGAGKHFSAGHDIGTPGRDINESFDRTSLWYDHVNKPGGEFLYAREQEVYLGMCR
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHH
RWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFADPVVRMGIPGVEYFAHPYEL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCHHHHCCCHHC
HPRIAKEFLFLGERMSAERAERMGMVNRVVPRDALEDAVYGMAAKVAQMPRLGLTLTKQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELISGDKLGGYDARAMAASQRTGEGKA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA