Click here to switch to the map view.

The map label for this gene is bepR [H]

Identifier: 73541206

GI number: 73541206

Start: 1635366

End: 1635992

Strand: Direct

Name: bepR [H]

Synonym: Reut_A1515

Alternate gene names: 73541206

Gene position: 1635366-1635992 (Clockwise)

Preceding gene: 73541205

Following gene: 73541207

Centisome position: 42.96

GC content: 69.38

Gene sequence:

>627_bases
ATGGGCCGCCGCCGCCGCGAGGATGCGGCCATGACGCGCGAACGGGTCCTTGCCAGCGCCTGGCAGGTCATCCGGGAGCG
CGGCGCGCACTGCGTCACGCTGGAAGAGGTCGCACGCACCATTGGCATGACGCGCGGCGCCATCTACGGGCATTTCCGGT
CCCGGGCCGAACTGTTTCGCGCCTTGCTGACCGATGCCGAGGCCGAGATCTCGCTGCGGCTCGCGCGTTGTGATGCGGAC
GCGCCGGGGCAGCTCGAGCGCTTGCTTGCAGCGCTGCTCGATGGCGATGCGCTGGCGCCGCATGCGAACTTGCTGTCTGC
GGTGGTACAGCACCGCTGCACGGAAGACTGTGAGCTCTGCCCGCTGCGTGCGCACGTGCTGCAGCGCGCTGAATATGCAT
GCGAGCGGCTGCGGTCATGGCTGCCCGATCCGCAGCGCGCAAACCTGCTGCTGGCCCACCTGTGGGGCTTGCTGAGCGCG
CAGTCGCTATGGCTGGTGCCATCGAGCCTGGCGCATTGCGTCGCACCGTTGGCGCGGCTGTACGCAGGCGCCGATCTTCG
GCTGGCATCTCTGCCATGTGCATCCGTCGCCACTGCCGGGAGGGCGGCGGTGCGGGATACCCCCTAG

Upstream 100 bases:

>100_bases
GTGACGGACGTCATGACCTTCGGCGCCGATGGTCGCATCCGCAGCATGCGGGCCTACTGGGGGCCCGACGATCTTCACTT
CGTATAAGGCGCGCGCAGCC

Downstream 100 bases:

>100_bases
TCTGCTTGGACGAATCGGACACCCACGCCACTGACTACGATCGACTCACAAGCCATGCAAAAAGGCGGACGGGAGACAGC
GATGAAGCGGACTCGGTGGT

Product: regulatory protein, TetR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MGRRRREDAAMTRERVLASAWQVIRERGAHCVTLEEVARTIGMTRGAIYGHFRSRAELFRALLTDAEAEISLRLARCDAD
APGQLERLLAALLDGDALAPHANLLSAVVQHRCTEDCELCPLRAHVLQRAEYACERLRSWLPDPQRANLLLAHLWGLLSA
QSLWLVPSSLAHCVAPLARLYAGADLRLASLPCASVATAGRAAVRDTP

Sequences:

>Translated_208_residues
MGRRRREDAAMTRERVLASAWQVIRERGAHCVTLEEVARTIGMTRGAIYGHFRSRAELFRALLTDAEAEISLRLARCDAD
APGQLERLLAALLDGDALAPHANLLSAVVQHRCTEDCELCPLRAHVLQRAEYACERLRSWLPDPQRANLLLAHLWGLLSA
QSLWLVPSSLAHCVAPLARLYAGADLRLASLPCASVATAGRAAVRDTP
>Mature_207_residues
GRRRREDAAMTRERVLASAWQVIRERGAHCVTLEEVARTIGMTRGAIYGHFRSRAELFRALLTDAEAEISLRLARCDADA
PGQLERLLAALLDGDALAPHANLLSAVVQHRCTEDCELCPLRAHVLQRAEYACERLRSWLPDPQRANLLLAHLWGLLSAQ
SLWLVPSSLAHCVAPLARLYAGADLRLASLPCASVATAGRAAVRDTP

Specific function: Represses expression of bepDE [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786669, Length=117, Percent_Identity=29.0598290598291, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22845; Mature: 22713

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRRREDAAMTRERVLASAWQVIRERGAHCVTLEEVARTIGMTRGAIYGHFRSRAELFR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLTDAEAEISLRLARCDADAPGQLERLLAALLDGDALAPHANLLSAVVQHRCTEDCELC
HHHHCCHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHH
PLRAHVLQRAEYACERLRSWLPDPQRANLLLAHLWGLLSAQSLWLVPSSLAHCVAPLARL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGADLRLASLPCASVATAGRAAVRDTP
HCCCCCEEHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GRRRREDAAMTRERVLASAWQVIRERGAHCVTLEEVARTIGMTRGAIYGHFRSRAELFR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLTDAEAEISLRLARCDADAPGQLERLLAALLDGDALAPHANLLSAVVQHRCTEDCELC
HHHHCCHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHH
PLRAHVLQRAEYACERLRSWLPDPQRANLLLAHLWGLLSAQSLWLVPSSLAHCVAPLARL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGADLRLASLPCASVATAGRAAVRDTP
HCCCCCEEHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]