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The map label for this gene is stc [H]

Identifier: 73541152

GI number: 73541152

Start: 1573742

End: 1575649

Strand: Direct

Name: stc [H]

Synonym: Reut_A1458

Alternate gene names: 73541152

Gene position: 1573742-1575649 (Clockwise)

Preceding gene: 73541148

Following gene: 73541153

Centisome position: 41.34

GC content: 67.3

Gene sequence:

>1908_bases
ATGCCACTTGCACCCGCTGCCCTTGCACGCGACGCCTCGGCGGCGCGGCAGAATTTCCTCGAAGGAAAGGATTTGCCCGC
CGGCATGGTGCCCGACCCGATCGTGCGTTCGTGGCAGCGCGCTGTGCAGGCCGGCGTGCGGCCCGAGCAGCGCCTGCTGT
TCTCGGATGTCGTCACACGCAGCCAGTGGCGGCGTGCCGAAGAAGAGAACCAGGCGCTCATCACGATGGCCGCTACCGAT
ATGGATATCCTTGCCGGCGCATTTCCGTCGCAGCATTGGATCGTGCTGTGCACGAATGCGCAAGGCACGATCGTGGCGTC
GCACGGTCGGCTCGGCGCGGGCCCTACGGAGCCGTCGCCATTGCAGCATGGACGGATGCTGTCGGAGGAAGGCATTGGCA
CCAATGCGCCCGGTTGCGTGCTGGAAGAGCGCGGCGGCCCTGGTATCGAGATTCGCCGGGGCGAGCACTATCTGCATGAA
CTCGTCGACGTGGTCTGCGCGGCAGCGCCTATCTTCGATTGCCATGAGCAGCTGATTGGCGTGCTCGATGTGACTGGCTT
CGGCGTGGACCTGCCGCGCTACACGCTGTCGCGAGTACAGGCGGCTGCCATGTCGATCGGCAACCGAACGTTCGAACGGC
TGCCCGGCTGCCGCGTGGTGCGCCTGCATCATGACTACCGCATGTTGCAGACGCCGGTAGAGGGCGTGATCGCCGTATCG
GAGGACGGCGTGGTGGTCGCAGCGAACCGCGCGGCGCGGCAGATGCTGCATCTGTCCGATGCGGCTCTTGGGGTCACCGA
AATCGGCAGCCTGCTGGTTGGCGGCCTGCGTGGCCTTGGCGGTTCCGCGCCTGCGATGGTCCATACCCACGGAGGCGAGC
GTCTGCACGTCGTGGCGGCGCATCCGGCGGGCACGCGGACGGCGTCCTACCCAGGCAGTACGCCACAAGCTGCTGGCGCG
CCGCAGGTCATCGCGGATGGGGCGCTCGGCCGCGTCTTTGGCAAGGCCATCATGGCGGTGCGCGAACAGGTGCCGCTGAT
CCTGCTCGGCGAGACCGGCACGGGCAAGAGCATGCTGGCGCGCATGCTGCACGAGGCGAGCCGGCCCGATGGCAAATTCA
TTTCGCTGAACTGTTCGGCAATTCCGGAAGGCCTGGTGGAGGCAGAGCTGTTCGGCTATGCCGATGGCGCCTTCACCGGC
AGCCGCCGGGGCGGCTGCGCGGGCAAGATCGAGCAGGCCAACCACGGCACGCTGTTTCTGGACGAGATCGGCGACATGCC
GCTCGCGTTGCAGACGCGCCTGCTCAGCGTGCTGCAGGAGCGCAGCGTCACGCGCGTGGGCGGCGCTGCGTCCATTGCGG
TCGATATCTCCGTGGTCTGCGCCACGCACCGCAATCTGCAGGAACTCGTGCGCGAGGGCGTATTTCGCGAGGACCTGTTC
TTCCGCCTCAACGGCATGTCGGTACGCATTCCCGCGCTGCGCGAACGTACCGACCTGCCGGAACTGATCGACAGCACGCT
GTCAGCGTTATCGCGCGGCCGCCGCAAGGTGCTCGACGCCGACGTGGTGGCGTTGCTGATGTCCCATGCATGGCCGGGCA
ACGTGCGCGAACTCCATCAGGTGTTGCGCGCGGCCGTCGCGCTTTCCGGCGAAGATGTGCAGATCCGCCGCGAACATCTC
GATGAAAGCTGGCTCGAATCAGCCGTCGATACGGCCGTCGCCACGGCGCCAGGGACGGCCACGCCGACGCCCCGCTCGCC
GACACGGCTGGCCGACGTTGAGAGCCGCATGATCGAGCGCACGCTCGCCGAACTGGGCGGCAACCGCTCGCAGGCGGCCA
AGGCGCTGGGTATCTCGCGCGCGACCTTGTACCGGAAGCTGGCCCAGGACAGGGACAAGGGCCGCTAG

Upstream 100 bases:

>100_bases
CGCCAGTGGCGGCGCGGCGCGAAGACCGACCGGTCTCACGCGAAGGCCGGCATCCCGCTGTCGTGCCCGCTGCGCACGCT
GGCCAACGGAGACAAACGCA

Downstream 100 bases:

>100_bases
TTTTCCGCTGCCTCAATCTGCGCCGACTGTCTCGGGCGGACTGACTCAAGCTGAGACAGTCCGCCGCGCATCCTCCCGCA
TATCCCCCTCGAAAAGGGCC

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MPLAPAALARDASAARQNFLEGKDLPAGMVPDPIVRSWQRAVQAGVRPEQRLLFSDVVTRSQWRRAEEENQALITMAATD
MDILAGAFPSQHWIVLCTNAQGTIVASHGRLGAGPTEPSPLQHGRMLSEEGIGTNAPGCVLEERGGPGIEIRRGEHYLHE
LVDVVCAAAPIFDCHEQLIGVLDVTGFGVDLPRYTLSRVQAAAMSIGNRTFERLPGCRVVRLHHDYRMLQTPVEGVIAVS
EDGVVVAANRAARQMLHLSDAALGVTEIGSLLVGGLRGLGGSAPAMVHTHGGERLHVVAAHPAGTRTASYPGSTPQAAGA
PQVIADGALGRVFGKAIMAVREQVPLILLGETGTGKSMLARMLHEASRPDGKFISLNCSAIPEGLVEAELFGYADGAFTG
SRRGGCAGKIEQANHGTLFLDEIGDMPLALQTRLLSVLQERSVTRVGGAASIAVDISVVCATHRNLQELVREGVFREDLF
FRLNGMSVRIPALRERTDLPELIDSTLSALSRGRRKVLDADVVALLMSHAWPGNVRELHQVLRAAVALSGEDVQIRREHL
DESWLESAVDTAVATAPGTATPTPRSPTRLADVESRMIERTLAELGGNRSQAAKALGISRATLYRKLAQDRDKGR

Sequences:

>Translated_635_residues
MPLAPAALARDASAARQNFLEGKDLPAGMVPDPIVRSWQRAVQAGVRPEQRLLFSDVVTRSQWRRAEEENQALITMAATD
MDILAGAFPSQHWIVLCTNAQGTIVASHGRLGAGPTEPSPLQHGRMLSEEGIGTNAPGCVLEERGGPGIEIRRGEHYLHE
LVDVVCAAAPIFDCHEQLIGVLDVTGFGVDLPRYTLSRVQAAAMSIGNRTFERLPGCRVVRLHHDYRMLQTPVEGVIAVS
EDGVVVAANRAARQMLHLSDAALGVTEIGSLLVGGLRGLGGSAPAMVHTHGGERLHVVAAHPAGTRTASYPGSTPQAAGA
PQVIADGALGRVFGKAIMAVREQVPLILLGETGTGKSMLARMLHEASRPDGKFISLNCSAIPEGLVEAELFGYADGAFTG
SRRGGCAGKIEQANHGTLFLDEIGDMPLALQTRLLSVLQERSVTRVGGAASIAVDISVVCATHRNLQELVREGVFREDLF
FRLNGMSVRIPALRERTDLPELIDSTLSALSRGRRKVLDADVVALLMSHAWPGNVRELHQVLRAAVALSGEDVQIRREHL
DESWLESAVDTAVATAPGTATPTPRSPTRLADVESRMIERTLAELGGNRSQAAKALGISRATLYRKLAQDRDKGR
>Mature_634_residues
PLAPAALARDASAARQNFLEGKDLPAGMVPDPIVRSWQRAVQAGVRPEQRLLFSDVVTRSQWRRAEEENQALITMAATDM
DILAGAFPSQHWIVLCTNAQGTIVASHGRLGAGPTEPSPLQHGRMLSEEGIGTNAPGCVLEERGGPGIEIRRGEHYLHEL
VDVVCAAAPIFDCHEQLIGVLDVTGFGVDLPRYTLSRVQAAAMSIGNRTFERLPGCRVVRLHHDYRMLQTPVEGVIAVSE
DGVVVAANRAARQMLHLSDAALGVTEIGSLLVGGLRGLGGSAPAMVHTHGGERLHVVAAHPAGTRTASYPGSTPQAAGAP
QVIADGALGRVFGKAIMAVREQVPLILLGETGTGKSMLARMLHEASRPDGKFISLNCSAIPEGLVEAELFGYADGAFTGS
RRGGCAGKIEQANHGTLFLDEIGDMPLALQTRLLSVLQERSVTRVGGAASIAVDISVVCATHRNLQELVREGVFREDLFF
RLNGMSVRIPALRERTDLPELIDSTLSALSRGRRKVLDADVVALLMSHAWPGNVRELHQVLRAAVALSGEDVQIRREHLD
ESWLESAVDTAVATAPGTATPTPRSPTRLADVESRMIERTLAELGGNRSQAAKALGISRATLYRKLAQDRDKGR

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=293, Percent_Identity=43.3447098976109, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1786524, Length=335, Percent_Identity=40.5970149253731, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789233, Length=354, Percent_Identity=37.2881355932203, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1790437, Length=312, Percent_Identity=37.5, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1790299, Length=351, Percent_Identity=39.8860398860399, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1788905, Length=306, Percent_Identity=37.9084967320261, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=37.3417721518987, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI1789087, Length=329, Percent_Identity=35.258358662614, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87082152, Length=290, Percent_Identity=39.6551724137931, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1787583, Length=296, Percent_Identity=37.1621621621622, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87081872, Length=312, Percent_Identity=33.974358974359, Blast_Score=159, Evalue=7e-40,
Organism=Escherichia coli, GI87081858, Length=549, Percent_Identity=27.3224043715847, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789828, Length=217, Percent_Identity=33.6405529953917, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 67916; Mature: 67784

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLAPAALARDASAARQNFLEGKDLPAGMVPDPIVRSWQRAVQAGVRPEQRLLFSDVVTR
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SQWRRAEEENQALITMAATDMDILAGAFPSQHWIVLCTNAQGTIVASHGRLGAGPTEPSP
HHHHHHHCCCCEEEEEEECCHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCC
LQHGRMLSEEGIGTNAPGCVLEERGGPGIEIRRGEHYLHELVDVVCAAAPIFDCHEQLIG
CHHCCCHHHCCCCCCCCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHH
VLDVTGFGVDLPRYTLSRVQAAAMSIGNRTFERLPGCRVVRLHHDYRMLQTPVEGVIAVS
HHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECHHHHHHCCCCCEEEEC
EDGVVVAANRAARQMLHLSDAALGVTEIGSLLVGGLRGLGGSAPAMVHTHGGERLHVVAA
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEE
HPAGTRTASYPGSTPQAAGAPQVIADGALGRVFGKAIMAVREQVPLILLGETGTGKSMLA
CCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
RMLHEASRPDGKFISLNCSAIPEGLVEAELFGYADGAFTGSRRGGCAGKIEQANHGTLFL
HHHHHHCCCCCCEEEEECHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEH
DEIGDMPLALQTRLLSVLQERSVTRVGGAASIAVDISVVCATHRNLQELVREGVFREDLF
HHHCCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEEHHHHHHHHHHHCCCHHHHHH
FRLNGMSVRIPALRERTDLPELIDSTLSALSRGRRKVLDADVVALLMSHAWPGNVRELHQ
EEECCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VLRAAVALSGEDVQIRREHLDESWLESAVDTAVATAPGTATPTPRSPTRLADVESRMIER
HHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
TLAELGGNRSQAAKALGISRATLYRKLAQDRDKGR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLAPAALARDASAARQNFLEGKDLPAGMVPDPIVRSWQRAVQAGVRPEQRLLFSDVVTR
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SQWRRAEEENQALITMAATDMDILAGAFPSQHWIVLCTNAQGTIVASHGRLGAGPTEPSP
HHHHHHHCCCCEEEEEEECCHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCC
LQHGRMLSEEGIGTNAPGCVLEERGGPGIEIRRGEHYLHELVDVVCAAAPIFDCHEQLIG
CHHCCCHHHCCCCCCCCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHH
VLDVTGFGVDLPRYTLSRVQAAAMSIGNRTFERLPGCRVVRLHHDYRMLQTPVEGVIAVS
HHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECHHHHHHCCCCCEEEEC
EDGVVVAANRAARQMLHLSDAALGVTEIGSLLVGGLRGLGGSAPAMVHTHGGERLHVVAA
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEE
HPAGTRTASYPGSTPQAAGAPQVIADGALGRVFGKAIMAVREQVPLILLGETGTGKSMLA
CCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
RMLHEASRPDGKFISLNCSAIPEGLVEAELFGYADGAFTGSRRGGCAGKIEQANHGTLFL
HHHHHHCCCCCCEEEEECHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEH
DEIGDMPLALQTRLLSVLQERSVTRVGGAASIAVDISVVCATHRNLQELVREGVFREDLF
HHHCCCCHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEEHHHHHHHHHHHCCCHHHHHH
FRLNGMSVRIPALRERTDLPELIDSTLSALSRGRRKVLDADVVALLMSHAWPGNVRELHQ
EEECCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VLRAAVALSGEDVQIRREHLDESWLESAVDTAVATAPGTATPTPRSPTRLADVESRMIER
HHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
TLAELGGNRSQAAKALGISRATLYRKLAQDRDKGR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA