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The map label for this gene is opuBB [H]

Identifier: 73541145

GI number: 73541145

Start: 1565833

End: 1567314

Strand: Direct

Name: opuBB [H]

Synonym: Reut_A1451

Alternate gene names: 73541145

Gene position: 1565833-1567314 (Clockwise)

Preceding gene: 73541140

Following gene: 73541146

Centisome position: 41.14

GC content: 68.35

Gene sequence:

>1482_bases
ATGGCCGCGTGCTTCGCCGGCATGCTGATTGCGCTTGCGTCTGCATGCCAGGCTCAGGGCGGCGACAGCCTCCGCGTCGG
TTCCAAGCGCTTTACCGAGTCCTACATCCTTGGGGAATTGCTGACGCAAGCTGCCGGCAATGCGCGTCATCACGCGGGGC
TGGGCAATTCCGCGATCGTGTTCGAAGCGTTAAGGTCGGGCAGCATTGACCTCTATCCCGACTACACCGGCACGCTCGCG
AGCGAGATCCTGAAGCTGCCGCCGGGCGCGACGCTGGCACAGATCAACGATGCGCTGCGGCCGATGGGGCTCGGCGCGGG
CATCGCGCTGGGATTCGAGAACACCTATGCGCTGGCTGTGCAGGAAACGCGTGCCCCTGGCTTGCGCCGGCTGAGCGATC
TGGCGCGGCAGTCGCAGTTGCGCATGGGCCTGTCGCATGAGTTCCTGGGGCGTGCCGATGGATGGCCGGGACTGGCCAGG
CGTTATGGGCTCCCGCAGAAGCCGGTCGGACTCGACCACGGTGTAGCCTACGAAGCGTTGGCAGCCGGGCAGGTCGATGT
GATCGACATCTATTCGACGGACGCCAAGATCCGCAAATACCAGTTGCGCGTGCTAGAGGATGATTTGCACTTCTTTCCGC
GCTATGACGCCGTGGTCGTTTACCGGCTGGACGTGCCGCGCCGGTTTCCGGCGGCTTGGCAGGCGCTGCAGGCGCTGGCC
GGACGCATCAGCGCGGCGGACATGGTGGCGATGAACGCGGCGGCCGAAATCGACGGCCAGTCGTTCGCGGCGATCGCGCG
AGACTTCCTGTCCGGCCATGCGGCGAAGGCGCCAGCACGCGCCGGCCTGATGCAGGCGCTGCTTGATACCGACACGCTGC
GCCTGACACGCCGCCACGTTGCGCTGGTGGTTGGCGCCGTGGGCGCGGCCACTCTCGCGGGCGTGCCGCTCGGCATCGTG
TCGGCGCGGCGTCGGCGGCTGGGGCAGGGTGTGCTCGGCGTGGTCAGCATGCTGCAGACGGTGCCGTCGCTGGCGCTGCT
GGCCATGCTGATTCCGTTGCTCGGCCGCATCGGCGTCTGGCCGGCGATGGTGGCACTGTTCCTCTACGCATTGCTGCCGA
TCGTGCGCAATACCTGCACGGGGCTGCAGCAGGTTTCCGTCAGCATGCGGGACGCGGCGCGTGCGCTGGGCCTGCGCGAT
CTGCAGGTGCTGCGTTACGTCGAACTGCCGCTGGCGCTGCCGGTGGTACTGGCCGGCGTGAAGACCGCGGCGATCATCAG
CGTGGGGACCGCGACCATCGCGGCGTTCGTCGGCGCCGGGGGCTACGGCGAGCGCATTGCCACCGGGCTAGCGCTCAACG
ACACGGTGATGCTGCTGGCCGGCGCCATACCCGCCGCCGTGCTGGCCCTGGCGGTCCAGGCCGGATTCGAGTTGCTGGAA
TGGGCGCTGCGCCGGAAGCGGCACGCCGGGCCCCCCATCTGA

Upstream 100 bases:

>100_bases
CCCGCCTATGATGTAGAGATGCCGGATGCACATCGGCCAACCACGCCCCGCCGGAGCCGACGCTTTGTCCTTATTCAGCC
GCAGAGGTGTGTTTCCCGGC

Downstream 100 bases:

>100_bases
TATGCAAGAATTCACGATATCTGCTGCTGTCATGTCCGCAGGCTGGCGCCGATAATCGGCGCCAGGGACTGGCAGCGCAA
GGGCGGCTGCCTCCCCGAGA

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MAACFAGMLIALASACQAQGGDSLRVGSKRFTESYILGELLTQAAGNARHHAGLGNSAIVFEALRSGSIDLYPDYTGTLA
SEILKLPPGATLAQINDALRPMGLGAGIALGFENTYALAVQETRAPGLRRLSDLARQSQLRMGLSHEFLGRADGWPGLAR
RYGLPQKPVGLDHGVAYEALAAGQVDVIDIYSTDAKIRKYQLRVLEDDLHFFPRYDAVVVYRLDVPRRFPAAWQALQALA
GRISAADMVAMNAAAEIDGQSFAAIARDFLSGHAAKAPARAGLMQALLDTDTLRLTRRHVALVVGAVGAATLAGVPLGIV
SARRRRLGQGVLGVVSMLQTVPSLALLAMLIPLLGRIGVWPAMVALFLYALLPIVRNTCTGLQQVSVSMRDAARALGLRD
LQVLRYVELPLALPVVLAGVKTAAIISVGTATIAAFVGAGGYGERIATGLALNDTVMLLAGAIPAAVLALAVQAGFELLE
WALRRKRHAGPPI

Sequences:

>Translated_493_residues
MAACFAGMLIALASACQAQGGDSLRVGSKRFTESYILGELLTQAAGNARHHAGLGNSAIVFEALRSGSIDLYPDYTGTLA
SEILKLPPGATLAQINDALRPMGLGAGIALGFENTYALAVQETRAPGLRRLSDLARQSQLRMGLSHEFLGRADGWPGLAR
RYGLPQKPVGLDHGVAYEALAAGQVDVIDIYSTDAKIRKYQLRVLEDDLHFFPRYDAVVVYRLDVPRRFPAAWQALQALA
GRISAADMVAMNAAAEIDGQSFAAIARDFLSGHAAKAPARAGLMQALLDTDTLRLTRRHVALVVGAVGAATLAGVPLGIV
SARRRRLGQGVLGVVSMLQTVPSLALLAMLIPLLGRIGVWPAMVALFLYALLPIVRNTCTGLQQVSVSMRDAARALGLRD
LQVLRYVELPLALPVVLAGVKTAAIISVGTATIAAFVGAGGYGERIATGLALNDTVMLLAGAIPAAVLALAVQAGFELLE
WALRRKRHAGPPI
>Mature_492_residues
AACFAGMLIALASACQAQGGDSLRVGSKRFTESYILGELLTQAAGNARHHAGLGNSAIVFEALRSGSIDLYPDYTGTLAS
EILKLPPGATLAQINDALRPMGLGAGIALGFENTYALAVQETRAPGLRRLSDLARQSQLRMGLSHEFLGRADGWPGLARR
YGLPQKPVGLDHGVAYEALAAGQVDVIDIYSTDAKIRKYQLRVLEDDLHFFPRYDAVVVYRLDVPRRFPAAWQALQALAG
RISAADMVAMNAAAEIDGQSFAAIARDFLSGHAAKAPARAGLMQALLDTDTLRLTRRHVALVVGAVGAATLAGVPLGIVS
ARRRRLGQGVLGVVSMLQTVPSLALLAMLIPLLGRIGVWPAMVALFLYALLPIVRNTCTGLQQVSVSMRDAARALGLRDL
QVLRYVELPLALPVVLAGVKTAAIISVGTATIAAFVGAGGYGERIATGLALNDTVMLLAGAIPAAVLALAVQAGFELLEW
ALRRKRHAGPPI

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=206, Percent_Identity=39.3203883495146, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788449, Length=151, Percent_Identity=43.046357615894, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789033, Length=157, Percent_Identity=32.484076433121, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 51980; Mature: 51849

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAACFAGMLIALASACQAQGGDSLRVGSKRFTESYILGELLTQAAGNARHHAGLGNSAIV
CHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHH
FEALRSGSIDLYPDYTGTLASEILKLPPGATLAQINDALRPMGLGAGIALGFENTYALAV
HHHHHCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
QETRAPGLRRLSDLARQSQLRMGLSHEFLGRADGWPGLARRYGLPQKPVGLDHGVAYEAL
ECCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHH
AAGQVDVIDIYSTDAKIRKYQLRVLEDDLHFFPRYDAVVVYRLDVPRRFPAAWQALQALA
HCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHH
GRISAADMVAMNAAAEIDGQSFAAIARDFLSGHAAKAPARAGLMQALLDTDTLRLTRRHV
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALVVGAVGAATLAGVPLGIVSARRRRLGQGVLGVVSMLQTVPSLALLAMLIPLLGRIGVW
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
PAMVALFLYALLPIVRNTCTGLQQVSVSMRDAARALGLRDLQVLRYVELPLALPVVLAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
KTAAIISVGTATIAAFVGAGGYGERIATGLALNDTVMLLAGAIPAAVLALAVQAGFELLE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WALRRKRHAGPPI
HHHHHHHCCCCCC
>Mature Secondary Structure 
AACFAGMLIALASACQAQGGDSLRVGSKRFTESYILGELLTQAAGNARHHAGLGNSAIV
HHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHH
FEALRSGSIDLYPDYTGTLASEILKLPPGATLAQINDALRPMGLGAGIALGFENTYALAV
HHHHHCCCEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
QETRAPGLRRLSDLARQSQLRMGLSHEFLGRADGWPGLARRYGLPQKPVGLDHGVAYEAL
ECCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHH
AAGQVDVIDIYSTDAKIRKYQLRVLEDDLHFFPRYDAVVVYRLDVPRRFPAAWQALQALA
HCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHH
GRISAADMVAMNAAAEIDGQSFAAIARDFLSGHAAKAPARAGLMQALLDTDTLRLTRRHV
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALVVGAVGAATLAGVPLGIVSARRRRLGQGVLGVVSMLQTVPSLALLAMLIPLLGRIGVW
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
PAMVALFLYALLPIVRNTCTGLQQVSVSMRDAARALGLRDLQVLRYVELPLALPVVLAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
KTAAIISVGTATIAAFVGAGGYGERIATGLALNDTVMLLAGAIPAAVLALAVQAGFELLE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WALRRKRHAGPPI
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]